Fabrications and Applications of Stimulus-Responsive Polymer Films and Patterns on Surfaces: A Review
Open accessAbstract
In the past two decades, we have witnessed significant progress in developing high performance stimuli-responsive polymeric materials. This review focuses on recent developments in the preparation and application of patterned stimuli-responsive polymers, including thermoresponsive layers, pH/ionic-responsive hydrogels, photo-responsive film, magnetically-responsive composites, electroactive composites, and solvent-responsive composites. Many important new applications for stimuli-responsive polymers lie in the field of nano- and micro-fabrication, where stimuli-responsive polymers are being established as important manipulation tools. Some techniques have been developed to selectively position organic molecules and then to obtain well-defined patterned substrates at the micrometer or submicrometer scale. Methods for patterning of stimuli-responsive hydrogels, including photolithography, electron beam lithography, scanning probe writing, and printing techniques (microcontact printing, ink-jet printing) were surveyed. We also surveyed the applications of nanostructured stimuli-responsive hydrogels, such as biotechnology (biological interfaces and purification of biomacromoles), switchable wettability, sensors (optical sensors, biosensors, chemical sensors), and actuators.
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The chemical configuration of stimuli-responsive nanomicelles may be changed intensely reacting to pH, temperature, light, ultrasound, and enzyme deprivation.
“Moreover, the chemical configuration of stimuli-responsive nanomicelles may be changed intensely reacting to pH, temperature, light, ultrasound, and enzyme deprivation (Figure 6) [131,132].”
From Recent Advances in Nanomicelles Delivery Systems. (2020) · cites this paper as [131]
The Application of Nanostructured Stimuli-Responsive Hydrogels section identifies polymeric micelles as a stimuli-responsive system, and the Biotechnology section discusses polymers responsive to pH, temperature, enzymes, and light. The cited paper does not establish that nanomicelles undergo intense changes in chemical configuration in response to all the listed stimuli; its mention of ultrasound concerns a fabrication method, not a micelle stimulus, and it does not describe enzyme deprivation. (LLM, conf=0.85)
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- Authors
- Chen, J.-K., & Chang, C.-J.
- Affiliations
- National Taiwan University of Science and Technology (TW)
- Feng Chia University (TW)
- Corresponding author
- Chang, Chi-Jung
- Venue
- Materials
- Publisher
- MDPI AG
- Published
- 2014-01-28
- Volume
- 7
- Issue
- 2
- Pages
- 805-875
- ISSN
- 1996-1944 (ISSN-L)
- PMC
- PMC5453090
- OpenAlex
- W2138602189
- Cited by
- 193
- References
- 301
- Citations by year
- 2026: 5 · 2025: 14 · 2024: 6 · 2023: 7 · 2022: 16 · 2021: 16 · 2020: 20 · 2019: 16 · 2018: 26 · 2017: 18 · 2016: 23 · 2015: 18 · 2014: 7 · 2013: 1
- FWCI
- 6.01
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Materials (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- National Science Council
- Topics
- Physical Sciences › Engineering › Mechanical Engineering › Advanced Materials and Mechanics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Physical Sciences › Engineering › Biomedical Engineering › Nanofabrication and Lithography Techniques
- Keywords
- stimuli-responsive polymers, thermosensitive hydrogel, pH-responsive hydrogels, electroactive composites, photolithography, electron beam lithography, microcontact printing, inkjet printing, switchable wettability, biosensors, chemical sensors, actuators, biointerfaces
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