Marine cyanobacteria compounds with anticancer properties: A review on the implication of apoptosis

Free radicals and antioxidants in normal physiological functions and human disease

Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T. D., Mazur, M., & Telser, J. (2007) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2006.07.001 · Cited by 14,269 · see citing works

Apoptosis: A Review of Programmed Cell Death

Elmore, S. (2007) · Toxicologic Pathology · doi:10.1080/01926230701320337 · Cited by 13,853 · see citing works

Antioxidants, Oxidative Damage and Oxygen Deprivation Stress: a Review

Blokhina, O. B. (2002) · Annals of Botany · doi:10.1093/aob/mcf118 · Cited by 4,018 · see citing works

Cyanobacteria secondary metabolites—the cyanotoxins

Carmichael, W. W. (1992) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1992.tb01858.x · Cited by 1,457 · see citing works

Targeting proteases: successes, failures and future prospects

Turk, B. (2006) · Nature Reviews Drug Discovery · doi:10.1038/nrd2092 · Cited by 1,366 · see citing works

Cyanobacterial toxins: risk management for health protection

Codd, G. A., Morrison, L. F., & Metcalf, J. S. (2004) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2004.02.016 · Cited by 1,155 · see citing works

The protein structures that shape caspase activity, specificity, activation and inhibition

Fuentes‐Prior, P., & Salvesen, G. S. (2004) · Biochemical Journal · doi:10.1042/bj20041142 · Cited by 877 · see citing works

Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis

Maeno, E., Ishizaki, Y., Kanaseki, T., Hazama, A., & Okada, Y. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.140216197 · Cited by 703 · see citing works

Structure and Biosynthesis of the Jamaicamides, New Mixed Polyketide-Peptide Neurotoxins from the Marine Cyanobacterium Lyngbya majuscula

Edwards, D. J., Márquez, B. L., Nogle, L. M., McPhail, K. L., Goeger, D. E., Roberts, M. A., & Gerwick, W. H. (2004) · Chemistry & Biology · doi:10.1016/j.chembiol.2004.03.030 · Cited by 506 · see citing works

Cathepsin D Triggers Bax Activation, Resulting in Selective Apoptosis-inducing Factor (AIF) Relocation in T Lymphocytes Entering the Early Commitment Phase to Apoptosis

Bidère, N., Lorenzo, H. K., Carmona, S., Laforge, M., Harper, F., Dumont, C., & Senik, A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301911200 · Cited by 435 · see citing works

Structure and Activity of Largazole, a Potent Antiproliferative Agent from the Floridian Marine Cyanobacterium <i>Symploca</i> sp.

Taori, K., Paul, V. J., & Luesch, H. (2008) · Journal of the American Chemical Society · doi:10.1021/ja7110064 · Cited by 428 · see citing works

Isolation of Dolastatin 10 from the Marine Cyanobacterium <i>Symploca</i> Species VP642 and Total Stereochemistry and Biological Evaluation of Its Analogue Symplostatin 1

Luesch, H., Moore, R. E., Paul, V. J., Mooberry, S. L., & Corbett, T. H. (2001) · Journal of Natural Products · doi:10.1021/np010049y · Cited by 378 · see citing works

Total Structure Determination of Apratoxin A, a Potent Novel Cytotoxin from the Marine Cyanobacterium <i>Lyngbya </i><i>m</i><i>ajuscula</i>

Luesch, H., Yoshida, W. Y., Moore, R. E., Paul, V. J., & Corbett, T. H. (2001) · Journal of the American Chemical Society · doi:10.1021/ja010453j · Cited by 373 · see citing works

Cyanobacteria: an emerging source for drug discovery

Singh, R. K., Tiwari, S. P., Rai, A. K., & Mohapatra, T. M. (2011) · The Journal of Antibiotics · doi:10.1038/ja.2011.21 · Cited by 370 · see citing works

Structure of curacin A, a novel antimitotic, antiproliferative and brine shrimp toxic natural product from the marine cyanobacterium Lyngbya majuscula

Gerwick, W. H., Proteau, P. J., Nagle, D. G., Hamel, E., Blokhin, A., & Slate, D. L. (1994) · The Journal of Organic Chemistry · doi:10.1021/jo00085a006 · Cited by 365 · see citing works

Toxins produced in cyanobacterial water blooms - toxicity and risks

Bláha, L., Babica, P., & Maršálek, B. (2009) · Interdisciplinary Toxicology · doi:10.2478/v10102-009-0006-2 · Cited by 316 · see citing works

Dietary flavonoids as proteasome inhibitors and apoptosis inducers in human leukemia cells

Chen, D., Daniel, K. G., Chen, M. S., Kuhn, D. J., Landis‐Piwowar, K. R., & Dou, Q. P. (2005) · Biochemical Pharmacology · doi:10.1016/j.bcp.2005.02.022 · Cited by 306 · see citing works

Apoptosis-based therapies and drug targets

Fischer, U., & Schulze‐Osthoff, K. (2005) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401556 · Cited by 280 · see citing works

The cytoskeleton and cell volume regulation

Pedersen, S. F., Hoffmann, E. K., & Mills, J. W. (2001) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/s1095-6433(01)00429-9 · Cited by 266 · see citing works

Biologically active secondary metabolites from marine cyanobacteria

Nunnery, J. K., Mevers, E. E., & Gerwick, W. H. (2010) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2010.09.019 · Cited by 265 · see citing works

Signaling pathways in mitochondrial dysfunction and aging

Mammucari, C., & Rizzuto, R. (2010) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2010.07.003 · Cited by 239 · see citing works

Coibamide A, a Potent Antiproliferative Cyclic Depsipeptide from the Panamanian Marine Cyanobacterium <i>Leptolyngbya</i> sp.

Medina, R. A., Goeger, D. E., Hills, P., Mooberry, S. L., Huang, N., Romero, L. I., Ortega-Barría, E., Gerwick, W. H., & McPhail, K. L. (2008) · Journal of the American Chemical Society · doi:10.1021/ja801383f · Cited by 231 · see citing works

Apoptosis: why and how does it occur in biology?

Ulukaya, E., Açılan, C., & Yilmaz, Y. N. (2011) · Cell Biochemistry and Function · doi:10.1002/cbf.1774 · Cited by 229 · see citing works

Mitochondrial dysfunction in brain aging: Role of oxidative stress and cardiolipin

Paradies, G., Petrosillo, G., Paradies, V., & Ruggiero, F. M. (2011) · Neurochemistry International · doi:10.1016/j.neuint.2010.12.016 · Cited by 220 · see citing works

Symplocamide A, a Potent Cytotoxin and Chymotrypsin Inhibitor from the Marine Cyanobacterium Symploca sp.

Linington, R. G., Edwards, D. J., Shuman, C. F., McPhail, K. L., Matainaho, T. K., & Gerwick, W. H. (2007) · Journal of Natural Products · doi:10.1021/np070280x · Cited by 190 · see citing works

Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly

Marquez, B. L., Watts, K. S., Yokochi, A., Roberts, M. A., Verdier-Pinard, P., Jimenez, J. I., Hamel, E., Scheuer, P. J., & Gerwick, W. H. (2002) · Journal of Natural Products · doi:10.1021/np0106283 · Cited by 181 · see citing works

Isolation, Structure Determination, and Biological Activity of Lyngbyabellin A from the Marine Cyanobacterium Lyngbya majuscula

Luesch, H., Yoshida, W. Y., Moore, R. E., Paul, V. J., & Mooberry, S. L. (2000) · Journal of Natural Products · doi:10.1021/np990543q · Cited by 166 · see citing works

New apratoxins of marine cyanobacterial origin from guam and palau

Luesch, H. (2002) · Bioorganic & Medicinal Chemistry · doi:10.1016/s0968-0896(02)00014-7 · Cited by 165 · see citing works

Bcl-2 Prevents Caspase-independent Cell Death

Okuno, S.-I., Shimizu, S., Ito, T., Nomura, M., Hamada, E., Tsujimoto, Y., & Matsuda, H. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.51.34272 · Cited by 159 · see citing works

Apratoxin D, a Potent Cytotoxic Cyclodepsipeptide from Papua New Guinea Collections of the Marine Cyanobacteria Lyngbya majuscula and Lyngbya sordida

Gutiérrez, M., Suyama, T. L., Engene, N., Wingerd, J. S., Matainaho, T. K., & Gerwick, W. H. (2008) · Journal of Natural Products · doi:10.1021/np800121a · Cited by 156 · see citing works

Lagunamides A and B: Cytotoxic and Antimalarial Cyclodepsipeptides from the Marine Cyanobacterium Lyngbya majuscula

Tripathi, A., Puddick, J., Prinsep, M. R., Rottmann, M., & Tan, L. T. (2010) · Journal of Natural Products · doi:10.1021/np100442x · Cited by 151 · see citing works

Apratoxin A Reversibly Inhibits the Secretory Pathway by Preventing Cotranslational Translocation

Liu, Y., Law, B. K., & Luesch, H. (2009) · Molecular Pharmacology · doi:10.1124/mol.109.056085 · Cited by 148 · see citing works

Symplostatin 2: A Dolastatin 13 Analogue from the Marine Cyanobacterium Symploca hydnoides

Harrigan, G. G., Luesch, H., Yoshida, W. Y., Moore, R. E., Nagle, D. G., & Paul, V. J. (1999) · Journal of Natural Products · doi:10.1021/np980553b · Cited by 148 · see citing works

Bisebromoamide, a Potent Cytotoxic Peptide from the Marine Cyanobacterium Lyngbya sp.: Isolation, Stereostructure, and Biological Activity

Teruya, T., Sasaki, H., Fukazawa, H., & Suenaga, K. (2009) · Organic Letters · doi:10.1021/ol9020546 · Cited by 141 · see citing works

Isolation of Swinholide A and Related Glycosylated Derivatives from Two Field Collections of Marine Cyanobacteria

Andrianasolo, E. H., Gross, H., Goeger, D. E., Musafija-Girt, M., McPhail, K. L., Leal, R. M., Mooberry, S. L., & Gerwick, W. H. (2005) · Organic Letters · doi:10.1021/ol050188x · Cited by 139 · see citing works

Filamentous tropical marine cyanobacteria: a rich source of natural products for anticancer drug discovery

Tan, L. T. (2010) · Journal of Applied Phycology · doi:10.1007/s10811-010-9506-x · Cited by 135 · see citing works

Symplostatin 1: A Dolastatin 10 Analogue from the Marine Cyanobacterium Symploca hydnoides

Harrigan, G. G., Luesch, H., Yoshida, W. Y., Moore, R. E., Nagle, D. G., Paul, V. J., Mooberry, S. L., Corbett, T. H., & Valeriote, F. A. (1998) · Journal of Natural Products · doi:10.1021/np980321c · Cited by 133 · see citing works

Aurilides B and C, Cancer Cell Toxins from a Papua New Guinea Collection of the Marine Cyanobacterium Lyngbya majuscula

Han, B., Gross, H., Goeger, D. E., Mooberry, S. L., & Gerwick, W. H. (2006) · Journal of Natural Products · doi:10.1021/np0503911 · Cited by 133 · see citing works

Apratoxin E, a Cytotoxic Peptolide from a Guamanian Collection of the Marine Cyanobacterium Lyngbya bouillonii

Matthew, S., Schupp, P. J., & Luesch, H. (2008) · Journal of Natural Products · doi:10.1021/np700717s · Cited by 132 · see citing works

Lyngbyastatins 5–7, Potent Elastase Inhibitors from Floridian Marine Cyanobacteria, Lyngbya spp.

Taori, K., Matthew, S., Rocca, J. R., Paul, V. J., & Luesch, H. (2007) · Journal of Natural Products · doi:10.1021/np0702436 · Cited by 132 · see citing works

Marine Natural Product Aurilide Activates the OPA1-Mediated Apoptosis by Binding to Prohibitin

Sato, S., Murata, A., Orihara, T., Shirakawa, T., Suenaga, K., Kigoshi, H., & Uesugi, M. (2011) · Chemistry & Biology · doi:10.1016/j.chembiol.2010.10.017 · Cited by 125 · see citing works

Structure and zymogen activation of caspases

Donepudi, M., & Grütter, M. G. (2002) · Biophysical Chemistry · doi:10.1016/s0301-4622(02)00151-5 · Cited by 123 · see citing works

Apoptotic cell death induced by intracellular proteolysis.

Williams, M. S., & Henkart, P. A. (1994) · The Journal of Immunology · doi:10.4049/jimmunol.153.9.4247 · Cited by 122 · see citing works

The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria

Jones, A. C., Monroe, E. A., Eisman, E. B., Gerwick, L. G., Sherman, D. H., & Gerwick, W. H. (2010) · Natural Product Reports · doi:10.1039/c000535e · Cited by 120 · see citing works

The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8

Wrasidlo, W., Mielgo, A., Torres, V. A., Barbero, S., Stoletov, K. V., Suyama, T. L., Klemke, R. L., Gerwick, W. H., Carson, D. A., & Stupack, D. G. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712198105 · Cited by 118 · see citing works

Antimicrobial and Cytotoxic Assessment of Marine Cyanobacteria - Synechocystis and Synechococcus

Martins, R., Ramos, M., Herfindal, L., Sousa, J., Skærven, K., & Vasconcelos, V. (2008) · Marine Drugs · doi:10.3390/md6010001 · Cited by 117 · see citing works

Lagunamide C, a cytotoxic cyclodepsipeptide from the marine cyanobacterium Lyngbya majuscula

Tripathi, A., Puddick, J., Prinsep, M. R., Rottmann, M., Chan, K. P., Chen, D. Y.-K., & Tan, L. T. (2011) · Phytochemistry · doi:10.1016/j.phytochem.2011.08.019 · Cited by 115 · see citing works

Evolved Diversification of a Modular Natural Product Pathway: Apratoxins F and G, Two Cytotoxic Cyclic Depsipeptides from a Palmyra Collection of Lyngbya bouillonii

Tidgewell, K. J., Engene, N., Byrum, T., Media, J. E., Doi, T., Valeriote, F. A., & Gerwick, W. H. (2010) · ChemBioChem · doi:10.1002/cbic.201000070 · Cited by 114 · see citing works

Upstream Regulatory Role for XIAP in Receptor-Mediated Apoptosis

Wilkinson, J. C., Cepero, E., Boise, L., & Duckett, C. S. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.16.7003-7014.2004 · Cited by 114 · see citing works

Cytotoxic Veraguamides, Alkynyl Bromide-Containing Cyclic Depsipeptides from the Marine Cyanobacterium cf. Oscillatoria margaritifera

Mevers, E. E., Liu, W.-T., Engene, N., Mohimani, H., Byrum, T., Pevzner, P. A., Dorrestein, P. C., Spadafora, C., & Gerwick, W. H. (2011) · Journal of Natural Products · doi:10.1021/np200077f · Cited by 110 · see citing works

Grassystatins A−C from Marine Cyanobacteria, Potent Cathepsin E Inhibitors That Reduce Antigen Presentation

Kwan, J. C., Eksioglu, E. A., Liu, C., Paul, V. J., & Luesch, H. (2009) · Journal of Medicinal Chemistry · doi:10.1021/jm9009394 · Cited by 109 · see citing works

Pitipeptolides A and B, New Cyclodepsipeptides from the Marine Cyanobacterium Lyngbya majuscula

Luesch, H., Pangilinan, R., Yoshida, W. Y., Moore, R. E., & Paul, V. J. (2001) · Journal of Natural Products · doi:10.1021/np000456u · Cited by 108 · see citing works

Antimicrobial and cytotoxic assessment of marine cyanobacteria - Synechocystis and Synechococcus.

Martins, R. F., Ramos, M. F., Herfindal, L., Sousa, J. A., Skærven, K., & Vasconcelos, V. M. (2008) · PubMed Central · Cited by 108 · see citing works

Biselyngbyaside, a Macrolide Glycoside from the Marine Cyanobacterium Lyngbya sp.

Teruya, T., Sasaki, H., Kitamura, K., Nakayama, T., & Suenaga, K. (2009) · Organic Letters · doi:10.1021/ol900579k · Cited by 106 · see citing works

Lyngbyastatin 4, a Dolastatin 13 Analogue with Elastase and Chymotrypsin Inhibitory Activity from the Marine Cyanobacterium Lyngbya confervoides

Matthew, S., Ross, C., Rocca, J. R., Paul, V. J., & Luesch, H. (2007) · Journal of Natural Products · doi:10.1021/np060471k · Cited by 106 · see citing works

Antillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels

Li, W. I., Berman, F. W., Okino, T., Yokokawa, F., Shioiri, T., Gerwick, W. H., & Murray, T. F. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.121085898 · Cited by 106 · see citing works

Role of apoptotic and necrotic cell death under physiologic conditions

Han, S. I., Kim, Y.-S., & Kim, T. (2008) · BMB Reports · doi:10.5483/bmbrep.2008.41.1.001 · Cited by 105 · see citing works

Hoiamide A, a Sodium Channel Activator of Unusual Architecture from a Consortium of Two Papua New Guinea Cyanobacteria

Pereira, A. R., Cao, Z., Murray, T. F., & Gerwick, W. H. (2009) · Chemistry & Biology · doi:10.1016/j.chembiol.2009.06.012 · Cited by 105 · see citing works

The Hoiamides, Structurally Intriguing Neurotoxic Lipopeptides from Papua New Guinea Marine Cyanobacteria

Choi, H., Pereira, A. R., Cao, Z., Shuman, C. F., Engene, N., Byrum, T., Matainaho, T. K., Murray, T. F., Mangoni, A., & Gerwick, W. H. (2010) · Journal of Natural Products · doi:10.1021/np100468n · Cited by 104 · see citing works

Calothrixins, a New Class of Human DNA Topoisomerase I Poisons

Khan, Q. A., Lu, J., & Hecht, S. M. (2009) · Journal of Natural Products · doi:10.1021/np8007232 · Cited by 104 · see citing works

New Lipopeptides from the Caribbean Cyanobacterium Lyngbya majuscula

Jiménez, J. I., & Scheuer, P. J. (2001) · Journal of Natural Products · doi:10.1021/np000462q · Cited by 103 · see citing works

Isolation, Structure Determination, and Biological Activity of Dolastatin 12 and Lyngbyastatin 1 from Lyngbya majuscula/Schizothrix calcicola Cyanobacterial Assemblages

Harrigan, G. G., Yoshida, W. Y., Moore, R. E., Nagle, D. G., Park, P. U., Biggs, J. S., Paul, V. J., Mooberry, S. L., Corbett, T. H., & Valeriote, F. A. (1998) · Journal of Natural Products · doi:10.1021/np9801211 · Cited by 103 · see citing works

Total synthesis of the cyclodepsipeptide apratoxin A and its analogues and assessment of their biological activities

Ma, D., Zou, B., Cai, G., Hu, X., & Liu, J. O. (2006) · Chemistry – A European Journal · doi:10.1002/chem.200600599 · Cited by 99 · see citing works

Lyngbyabellin B, a Toxic and Antifungal Secondary Metabolite from the Marine Cyanobacterium Lyngbya majuscula

Milligan, K. E., Márquez, B. L., Williamson, R. T., & Gerwick, W. H. (2000) · Journal of Natural Products · doi:10.1021/np000133y · Cited by 98 · see citing works

Largamides A−H, Unusual Cyclic Peptides from the Marine Cyanobacterium Oscillatoria sp.

Plaza, A., & Bewley, C. A. (2006) · The Journal of Organic Chemistry · doi:10.1021/jo061044e · Cited by 92 · see citing works

Pitipeptolides C–F, antimycobacterial cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula from Guam

Montaser, R., Paul, V. J., & Luesch, H. (2011) · Phytochemistry · doi:10.1016/j.phytochem.2011.07.014 · Cited by 91 · see citing works

Palmyramide A, a Cyclic Depsipeptide from a Palmyra Atoll Collection of the Marine CyanobacteriumLyngbya majuscula

Taniguchi, M., Nunnery, J. K., Engene, N., Esquenazi, E., Byrum, T., Dorrestein, P. C., & Gerwick, W. H. (2009) · Journal of Natural Products · doi:10.1021/np900428h · Cited by 90 · see citing works

A review of pharmacological and toxicological potentials of marine cyanobacterial metabolites

Nagarajan, M., Veerabadhran, M., & Sundararaman, M. (2011) · Journal of Applied Toxicology · doi:10.1002/jat.1717 · Cited by 90 · see citing works

The Wewakpeptins, Cyclic Depsipeptides from a Papua New Guinea Collection of the Marine Cyanobacterium Lyngbya semiplena

Han, B., Goeger, D. E., Maier, C. S., & Gerwick, W. H. (2005) · The Journal of Organic Chemistry · doi:10.1021/jo0478858 · Cited by 89 · see citing works

Malevamide D: Isolation and Structure Determination of an Isodolastatin H Analogue from the Marine CyanobacteriumSymplocahydnoides

Horgen, F. D., Kazmierski, E. B., Westenburg, H. E., Yoshida, W. Y., & Scheuer, P. J. (2002) · Journal of Natural Products · doi:10.1021/np010560r · Cited by 88 · see citing works

Growth Inhibition of Human Lymphoma Cell Lines by the Marine Products, Dolastatins 10 and 15

Beckwith, M., Urba, W. J., & Longo, D. L. (1993) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/85.6.483 · Cited by 87 · see citing works

In vitro pharmacology of cryptophycin 52 (LY355703) in human tumor cell lines

Wagner, M. M. F., Paul, D. C., Shih, C., Jordan, M. A., Wilson, L., & Williams, D. C. (1999) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s002800050871 · Cited by 87 · see citing works

The molecular pharmacology of symplostatin 1: A new antimitotic dolastatin 10 analog

Mooberry, S. L., Leal, R. M., Tinley, T. L., Luesch, H., Moore, R. E., & Corbett, T. H. (2003) · International Journal of Cancer · doi:10.1002/ijc.10982 · Cited by 87 · see citing works

Isolation and structure of five lyngbyabellin derivatives from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula

Han, B., McPhail, K. L., Gross, H., Goeger, D. E., Mooberry, S. L., & Gerwick, W. H. (2005) · Tetrahedron · doi:10.1016/j.tet.2005.09.036 · Cited by 87 · see citing works

Isolation of Homodolastatin 16, a New Cyclic Depsipeptide from a Kenyan Collection of Lyngbya majuscula

Davies‐Coleman, M. T., Dzeha, T. M., Gray, C. A., Hess, S. Y., Pannell, L. K., Hendricks, D. T., & Arendse, C. E. (2003) · Journal of Natural Products · doi:10.1021/np030014t · Cited by 86 · see citing works

Activity of dolastatin 10 against small-cell lung cancer in vitro and in vivo: Induction of apoptosis and bcl-2 modification

Kalemkerian, G. P., Ou, X., Adil, M. R., Rosati, R., Khoulani, M. M., Madan, S. K., & Pettit, G. R. (1999) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s002800050931 · Cited by 84 · see citing works

Cathepsin E: A mini review

Zaidi, N., & Kalbacher, H. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.12.163 · Cited by 84 · see citing works

Symplostatin 3, a New Dolastatin 10 Analogue from the Marine Cyanobacterium Symploca sp. VP452

Luesch, H., Yoshida, W. Y., Moore, R. E., Paul, V. J., Mooberry, S. L., & Corbett, T. H. (2001) · Journal of Natural Products · doi:10.1021/np010317s · Cited by 84 · see citing works

Belamide A, a new antimitotic tetrapeptide from a Panamanian marine cyanobacterium

Simmons, T. L., McPhail, K. L., Ortega‐Barría, E., Mooberry, S. L., & Gerwick, W. H. (2006) · Tetrahedron Letters · doi:10.1016/j.tetlet.2006.03.082 · Cited by 84 · see citing works

Isolation and Structure Determination of Nostocyclopeptides A1 and A2 from the Terrestrial Cyanobacterium Nostoc sp. ATCC53789

Golakoti, T., Yoshida, W. Y., Chaganty, S., & Moore, R. E. (2000) · Journal of Natural Products · doi:10.1021/np000316k · Cited by 83 · see citing works

Total Synthesis and Biological Evaluation of Largazole and Derivatives with Promising Selectivity for Cancers Cells

Zeng, X., Yin, B., Hu, Z., Liao, C., Liu, J., Li, S., Li, Z., Nicklaus, M. C., Zhou, G., & Jiang, S. (2010) · Organic Letters · doi:10.1021/ol100308a · Cited by 83 · see citing works

Changes in Elemental Content During Apoptotic Cell Death Studied by Electron Probe X-Ray Microanalysis

Fernández-Segura, E., Cañizares, F. J., Cubero, M. A., Warley, A., & Campos, A. (1999) · Experimental Cell Research · doi:10.1006/excr.1999.4657 · Cited by 83 · see citing works

Human cancer cell (Jurkat) killing by the cyanobacterial metabolite calothrixin A

Chen, X., Smith, G. D., & Waring, P. (2003) · Journal of Applied Phycology · doi:10.1023/a:1025134106985 · Cited by 82 · see citing works

Antioxidant potential of C-phycocyanin isolated from cyanobacterial species Lyngbya, Phormidium and Spirulina spp.

Patel, A. B., Mishra, S., & Ghosh, P. K. (2006) · PubMed · Cited by 82 · see citing works

Lyngbyaloside B, a New Glycoside Macrolide from a Palauan Marine Cyanobacterium,Lyngbyasp.

Luesch, H., Yoshida, W. Y., Harrigan, G. G., Doom, J. P., Moore, R. E., & Paul, V. J. (2002) · Journal of Natural Products · doi:10.1021/np0202879 · Cited by 82 · see citing works

Total synthesis and biological evaluation of (+)-kalkitoxin, a cytotoxic metabolite of the cyanobacterium Lyngbya majusculaElectronic supplementary information (ESI) available: 1H NMR spectrum of synthetic (+)-kalkitoxin in C6D6. See http://www.rsc.org/suppdata/ob/b4/b404205k/

White, J. D., Xu, Q., Lee, C.-S., & Valeriote, F. A. (2004) · Organic & Biomolecular Chemistry · doi:10.1039/b404205k · Cited by 82 · see citing works

Lyngbyastatins 8–10, Elastase Inhibitors with Cyclic Depsipeptide Scaffolds Isolated from the Marine Cyanobacterium Lyngbya semiplena

Kwan, J. C., Taori, K., Paul, V. J., & Luesch, H. (2009) · Marine Drugs · doi:10.3390/md7040528 · Cited by 81 · see citing works

Palmyrolide A, an Unusually Stabilized Neuroactive Macrolide from Palmyra Atoll Cyanobacteria

Pereira, A. R., Cao, Z., Engene, N., Soria-Mercado, I. E., Murray, T. F., & Gerwick, W. H. (2010) · Organic Letters · doi:10.1021/ol101752n · Cited by 81 · see citing works

Isolation and Structure Determination of Obyanamide, a Novel Cytotoxic Cyclic Depsipeptide from the Marine Cyanobacterium Lyngbya confervoides

Williams, P. G., Yoshida, W. Y., Moore, R. E., & Paul, V. J. (2001) · Journal of Natural Products · doi:10.1021/np0102253 · Cited by 81 · see citing works

Pompanopeptins A and B, new cyclic peptides from the marine cyanobacterium Lyngbya confervoides

Matthew, S., Ross, C., Paul, V. J., & Luesch, H. (2008) · Tetrahedron · doi:10.1016/j.tet.2008.02.035 · Cited by 80 · see citing works

Malyngamide 2, an Oxidized Lipopeptide with Nitric Oxide Inhibiting Activity from a Papua New Guinea Marine Cyanobacterium

Malloy, K. L., Villa, F. A., Engene, N., Matainaho, T. K., Gerwick, L. G., & Gerwick, W. H. (2010) · Journal of Natural Products · doi:10.1021/np1005407 · Cited by 78 · see citing works

Molassamide, a Depsipeptide Serine Protease Inhibitor from the Marine Cyanobacterium <i>Dichothrix utahensis</i>

Gunasekera, S. P., Miller, M. W., Kwan, J. C., Luesch, H., & Paul, V. J. (2010) · Journal of Natural Products · doi:10.1021/np900603f · Cited by 75 · see citing works

Kempopeptins A and B, Serine Protease Inhibitors with Different Selectivity Profiles from a Marine Cyanobacterium, Lyngbya sp.

Taori, K., Paul, V. J., & Luesch, H. (2008) · Journal of Natural Products · doi:10.1021/np8002172 · Cited by 74 · see citing works

The Isolation and Structure Elucidation of Tasiamide B, a 4-Amino-3-hydroxy-5-phenylpentanoic Acid Containing Peptide from the Marine Cyanobacterium Symploca sp.

Williams, P. G., Yoshida, W. Y., Moore, R. E., & Paul, V. J. (2003) · Journal of Natural Products · doi:10.1021/np030114z · Cited by 74 · see citing works

Cell-Morphology Profiling of a Natural Product Library Identifies Bisebromoamide and Miuraenamide A as Actin Filament Stabilizers

Sumiya, E., Shimogawa, H., Sasaki, H., Tsutsumi, M., Yoshita, K., Ojika, M., Suenaga, K., & Uesugi, M. (2011) · ACS Chemical Biology · doi:10.1021/cb1003459 · Cited by 72 · see citing works

Caylobolide A, a Unique 36-Membered Macrolactone from a Bahamian Lyngbya majuscula

MacMillan, J. B., & Molinski, T. F. (2002) · Organic Letters · doi:10.1021/ol025759p · Cited by 71 · see citing works

The Structure of Palau'amide, a Potent Cytotoxin from a Species of the Marine Cyanobacterium Lyngbya

Williams, P. G., Yoshida, W. Y., Quon, M. K., Moore, R. E., & Paul, V. J. (2003) · Journal of Natural Products · doi:10.1021/np034001r · Cited by 70 · see citing works

The neurotoxic lipopeptide kalkitoxin interacts with voltage-sensitive sodium channels in cerebellar granule neurons

LePage, K. T., Goeger, D. E., Yokokawa, F., Asano, T., Shioiri, T., Gerwick, W. H., & Murray, T. F. (2005) · Toxicology Letters · doi:10.1016/j.toxlet.2005.03.007 · Cited by 70 · see citing works

Bax:Bcl-2 ratio modulation by bryostatin 1 and novel antitubulin agents is important for susceptibility to drug induced apoptosis in the human early pre-B acute lymphoblastic leukemia cell line, Reh

Wall, N. R., Mohammad, R. M., & Al-Katib, A. M. (1999) · Leukemia Research · doi:10.1016/s0145-2126(99)00108-3 · Cited by 69 · see citing works

Structure–activity delineation of quinones related to the biologically active Calothrixin B

Bernardo, P. H., Chai, C. L. L., Guen, M. L., Smith, G. D., & Waring, P. (2006) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2006.09.090 · Cited by 69 · see citing works

Antillatoxin B, a Neurotoxic Lipopeptide from the Marine Cyanobacterium Lyngbya majuscula

Nogle, L. M., Okino, T., & Gerwick, W. H. (2001) · Journal of Natural Products · doi:10.1021/np010107f · Cited by 68 · see citing works

Alotamide A, a Novel Neuropharmacological Agent from the Marine Cyanobacterium Lyngbya bouillonii

Soria-Mercado, I. E., Pereira, A. R., Cao, Z., Murray, T. F., & Gerwick, W. H. (2009) · Organic Letters · doi:10.1021/ol901438b · Cited by 67 · see citing works

Localization of the Antimitotic Peptide and Depsipeptide Binding Site on β-Tubulin

Mitra, A., & Sept, D. (2004) · Biochemistry · doi:10.1021/bi0487387 · Cited by 67 · see citing works

Pitiprolamide, a Proline-Rich Dolastatin 16 Analogue from the Marine Cyanobacterium Lyngbya majuscula from Guam

Montaser, R., Abboud, K. A., Paul, V. J., & Luesch, H. (2010) · Journal of Natural Products · doi:10.1021/np1006839 · Cited by 66 · see citing works

Ulongapeptin, a Cytotoxic Cyclic Depsipeptide from a Palauan Marine Cyanobacterium Lyngbya sp.

Williams, P. G., Yoshida, W. Y., Quon, M. K., Moore, R. E., & Paul, V. J. (2003) · Journal of Natural Products · doi:10.1021/np030050s · Cited by 66 · see citing works

Caylobolide B, a Macrolactone from Symplostatin 1-Producing Marine Cyanobacteria Phormidium spp. from Florida

Salvador, L. A., Paul, V. J., & Luesch, H. (2010) · Journal of Natural Products · doi:10.1021/np100467d · Cited by 66 · see citing works

UV-B overexposure induces programmed cell death in a BY-2 tobacco cell line

Lytvyn, D. I., Yemets, A. I., & Blume, Y. B. (2009) · Environmental and Experimental Botany · doi:10.1016/j.envexpbot.2009.11.004 · Cited by 66 · see citing works

Biselyngbyaside, isolated from marine cyanobacteria, inhibits osteoclastogenesis and induces apoptosis in mature osteoclasts

Yonezawa, T., Mase, N., Sasaki, H., Teruya, T., Hasegawa, S., Cha, B., Yagasaki, K., Suenaga, K., Nagai, K., & Woo, J. (2012) · Journal of Cellular Biochemistry · doi:10.1002/jcb.23213 · Cited by 65 · see citing works

Tasipeptins A and B: New Cytotoxic Depsipeptides from the Marine CyanobacteriumSymplocasp.

Williams, P. G., Yoshida, W. Y., Moore, R. E., & Paul, V. J. (2003) · Journal of Natural Products · doi:10.1021/np020582t · Cited by 65 · see citing works

Isomalyngamide A, A-1 and their analogs suppress cancer cell migration in vitro

Chang, T. T., More, S. V., Lu, I.-H., Hsu, J., Chen, T.-J., Jen, Y. C., Lu, C., & Li, W. (2011) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2011.05.049 · Cited by 63 · see citing works

Carotenoids provide the major antioxidant defence in the globally significant N 2 ‐fixing marine cyanobacterium Trichodesmium

Kelman, D., Ben‐Amotz, A., & Berman‐Frank, I. (2009) · Environmental Microbiology · doi:10.1111/j.1462-2920.2009.01913.x · Cited by 63 · see citing works

Marine benthic cyanobacteria contain apoptosis-inducing activity synergizing with daunorubicin to kill leukemia cells, but not cardiomyocytes

Oftedal, L., Selheim, F., Wahlsten, M., Sivonen, K., Døskeland, S. O., & Herfindal, L. (2010) · Marine Drugs · doi:10.3390/md8102659 · Cited by 62 · see citing works

Characterization of apoptosis induced by marine natural products in non small cell lung cancer A549 cells

Catassi, A., Cesario, A., Arzani, D., Menichini, P., Alama, A., Bruzzo, C., Imperatori, A. S., Rotolo, N., Granone, P. L., & Russo, P. (2006) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-006-6264-7 · Cited by 60 · see citing works

Cathepsin D protects human neuroblastoma cells from doxorubicin-induced cell death

Sagulenko, V., Muth, D., Sagulenko, E., Paffhausen, T., Schwab, M., & Westermann, F. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn147 · Cited by 58 · see citing works

Malyngolide Dimer, a Bioactive Symmetric Cyclodepside from the Panamanian Marine Cyanobacterium Lyngbya majuscula

Gutiérrez, M., Tidgewell, K. J., Capson, T. L., Engene, N., Almanza, A., Schemies, J., Jung, M., & Gerwick, W. H. (2010) · Journal of Natural Products · doi:10.1021/np9005184 · Cited by 58 · see citing works

Apoptosis-based anticancer drugs

Zhang, J. Y. (2002) · Nature Reviews Drug Discovery · doi:10.1038/nrd742 · Cited by 55 · see citing works

Total Synthesis and Cytotoxicity Studies of a Cyclic Depsipeptide with Proposed Structure of Palau'amide

Zou, B., Long, K., & Ma, D. (2005) · Organic Letters · doi:10.1021/ol051685g · Cited by 54 · see citing works

Antineoplastic Agents. 536. New Sources of Naturally Occurring Cancer Cell Growth Inhibitors from Marine Organisms, Terrestrial Plants, and Microorganisms,

Pettit, G. R., Hogan, F., Xu, J., Tan, R., Nogawa, T., Cichacz, Z. A., Pettit, R. K., Du, J., Ye, Q.-H., Cragg, G. M. L., et al. (2008) · Journal of Natural Products · doi:10.1021/np700738k · Cited by 54 · see citing works

Tasiamide, a Cytotoxic Peptide from the Marine CyanobacteriumSymplocasp.

Williams, P. G., Yoshida, W. Y., Moore, R. E., & Paul, V. J. (2002) · Journal of Natural Products · doi:10.1021/np020184q · Cited by 49 · see citing works

Depsipeptides from a Guamanian marine cyanobacterium, Lyngbya bouillonii, with selective inhibition of serine proteases

Rubio, B. K., Parrish, S. M., Yoshida, W. Y., Schupp, P. J., Schils, T., & Williams, P. G. (2010) · Tetrahedron Letters · doi:10.1016/j.tetlet.2010.10.062 · Cited by 46 · see citing works

Tiglicamides A–C, cyclodepsipeptides from the marine cyanobacterium Lyngbya confervoides

Matthew, S., Paul, V. J., & Luesch, H. (2009) · Phytochemistry · doi:10.1016/j.phytochem.2009.09.010 · Cited by 45 · see citing works

Chemical Deterrence of a Marine Cyanobacterium against Sympatric and Non-sympatric Consumers

Capper, A., Cruz‐Rivera, E., Paul, V. J., & Tibbetts, I. R. (2005) · Hydrobiologia · doi:10.1007/s10750-005-1129-x · Cited by 45 · see citing works

A natural peptide, dolastatin 15, induces G2/M cell cycle arrest and apoptosis of human multiple myeloma cells

Sato, M., Sagawa, M., Nakazato, T., Ikeda, Y., & Kizaki, M. (2007) · International Journal of Oncology · doi:10.3892/ijo.30.6.1453 · Cited by 45 · see citing works

Two cytotoxic stereoisomers of malyngamide C, 8-epi-malyngamide C and 8-O-acetyl-8-epi-malyngamide C, from the marine cyanobacterium Lyngbya majuscula

Gross, H., McPhail, K. L., Goeger, D. E., Valeriote, F. A., & Gerwick, W. H. (2010) · Phytochemistry · doi:10.1016/j.phytochem.2010.07.001 · Cited by 41 · see citing works

Non-caspase proteases: triggers or amplifiers of apoptosis?

Schrader, K., Huai, J., Joeckel, L. T., Oberle, C., & Borner, C. (2010) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-010-0287-9 · Cited by 41 · see citing works

Hydrogen peroxide‐induced apoptosis in human gastric carcinoma MGC803 cells

Mao, Y., Song, G., Cai, Q., Liu, M., Luo, H., Shi, M., Ouyang, G., & Bao, S. (2006) · Cell Biology International · doi:10.1016/j.cellbi.2005.12.008 · Cited by 39 · see citing works

The novel antimicrotubule agent cryptophycin 52 (LY355703) induces apoptosis via multiple pathways in human prostate cancer cells.

Drew, L., Fine, R. L., Tamara, N., Douglas, G. P., & Petrylak, D. P. (2002) · PubMed · Cited by 39 · see citing works

Largamides A–C, Tiglic Acid-Containing Cyclodepsipeptides with Elastase-Inhibitory Activity from the Marine CyanobacteriumLyngbya confervoides

Matthew, S., Paul, V. J., & Luesch, H. (2009) · Planta Medica · doi:10.1055/s-0029-1185332 · Cited by 38 · see citing works

Inhibition of Human Leukocyte Elastase by Brunsvicamides A–C: Cyanobacterial Cyclic Peptides

Sisay, M. T., Hautmann, S., Mehner, C., König, G. M., Bajorath, J., & Gütschow, M. (2009) · ChemMedChem · doi:10.1002/cmdc.200900139 · Cited by 36 · see citing works

Phylogeny-Guided Isolation of Ethyl Tumonoate A from the Marine Cyanobacterium cf. Oscillatoria margaritifera

Engene, N., Choi, H., Esquenazi, E., Byrum, T., Villa, F. A., Cao, Z., Murray, T. F., Dorrestein, P. C., Gerwick, L. G., & Gerwick, W. H. (2011) · Journal of Natural Products · doi:10.1021/np200236c · Cited by 35 · see citing works

Isolation and Structure Determination of Malevamide E, a Dolastatin 14 Analogue, from the Marine Cyanobacterium Symploca laete-viridis

Adams, B., Pörzgen, P., Pittman, E. I., Yoshida, W. Y., Westenburg, H. E., & Horgen, F. D. (2008) · Journal of Natural Products · doi:10.1021/np070346o · Cited by 31 · see citing works

Antillatoxin is a sodium channel activator that displays unique efficacy in heterologously expressed rNav1.2, rNav1.4 and rNav1.5 alpha subunits

Cao, Z., Gerwick, W. H., & Murray, T. F. (2010) · BMC Neuroscience · doi:10.1186/1471-2202-11-154 · Cited by 31 · see citing works

Synthesis and evaluation of hermitamides A and B as human voltage-gated sodium channel blockers

Oliveira, E. O. D., Graf, K. M., Patel, M. K., Baheti, A. R., Kong, H., MacArthur, L. H., Dakshanamurthy, S., Wang, K., Brown, M. L., & Paige, M. A. (2011) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2011.05.043 · Cited by 25 · see citing works

Dolastatin 15 induces apoptosis and BCL-2 phosphorylation in small cell lung cancer cell lines.

Ali, M. A., Rosati, R., Pettit, G. R., & Kalemkerian, G. P. (1998) · PubMed · Cited by 23 · see citing works

Treatment of the P815 murine mastocytoma with cisplatin or etoposide up-regulates cell-surface Fas (CD95) expression and increases sensitivity to anti-Fas antibody-mediated cytotoxicity and to lysis by anti-CD3-activated killer-T cells

Williams, B. A., Makrigiannis, A. P., Blay, J., & Hoskin, D. W. (1997) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19971104)73:3 · Cited by 22 · see citing works

CHEMICAL ECOLOGY OF MARINE CYANOBACTERIAL SECONDARY METABOLITES: A MINI-REVIEW

Tan, L. T., & Goh, B. P. L. (2011) · Cited by 13 · see citing works

Leuprorelin acetate blood levels and dialysance after the administration of sustained-release leuprorelin acetate in a dialysis case complicated by prostate cancer

Saruki, K., Sekihara, T., Mashimo, M., Matsuo, H., & Sekiguchi, H. (1998) · The Prostate · doi:10.1002/(sici)1097-0045(19980215)34:3 · Cited by 11 · see citing works

[Nitrogen-fixing cyanobacteria: producents of hydrogen].

Tsygankov, A. A. (2007) · PubMed · Cited by 8 · see citing works

Autophagy as a target for anticancer therapy and its modulation by phytochemicals

Kim, M., Suh, D. H., Seoung, J., Kim, H. S., Chung, H. H., & Song, Y. S. (2020) · Journal of Food and Drug Analysis · doi:10.38212/2224-6614.2121 · Cited by 7 · see citing works

Marine Natural Products: A Source of Novel Anticancer Drugs

Khalifa, S. A. M., Elias, N., Farag, M. A., Chen, L., Saeed, A., Hegazy, M.-E. F., Moustafa, M. S., Abd El-Wahed, A., Al-Mousawi, S. M., Musharraf, S. G., et al. (2019) · Marine Drugs · doi:10.3390/md17090491 · Cited by 555 · see citing works

Marine natural products

Blunt, J. W., Copp, B. R., Keyzers, R. A., Munro, M. H. G., & Prinsep, M. R. (2014) · Natural Product Reports · doi:10.1039/c3np70117d · Cited by 488 · see citing works

Cyanobacteria and Cyanotoxins: From Impacts on Aquatic Ecosystems and Human Health to Anticarcinogenic Effects

Zanchett, G., & Oliveira-Filho, E. C. (2013) · Toxins · doi:10.3390/toxins5101896 · Cited by 327 · see citing works

Antimicrobial Compounds from Eukaryotic Microalgae against Human Pathogens and Diseases in Aquaculture

Falaise, C., François, C., Travers, M., Morga, B., Haure, J., Tremblay, R., Turcotte, F., Pasetto, P., Gastineau, R., Hardivillier, Y., et al. (2016) · Marine Drugs · doi:10.3390/md14090159 · Cited by 253 · see citing works

Tiny Microbes with a Big Impact: The Role of Cyanobacteria and Their Metabolites in Shaping Our Future

Mazard, S., Penesyan, A., Ostrowski, M. D., Paulsen, I. T., & Egan, S. (2016) · Marine Drugs · doi:10.3390/md14050097 · Cited by 154 · see citing works

Selected Methods of Extracting Carotenoids, Characterization, and Health Concerns: A Review

Adadi, P., Barakova, N. V., & Krivoshapkina, E. F. (2018) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.8b01407 · Cited by 123 · see citing works

Marine Cyanobacteria and Microalgae Metabolites—A Rich Source of Potential Anticancer Drugs

Mondal, A., Bose, S., Banerjee, S., Patra, J. K., Malik, J., Mandal, S. K., Kilpatrick, K. L., Das, G., Kerry, R. G., Fimognari, C., et al. (2020) · Marine Drugs · doi:10.3390/md18090476 · Cited by 119 · see citing works

Extraction, purification and characterization of phycoerythrin from Michrochaete and its biological activities

Hemlata, H., Afreen, S., & Fatma, T. (2017) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2017.11.012 · Cited by 109 · see citing works

New Drugs from the Sea: Pro-Apoptotic Activity of Sponges and Algae Derived Compounds

Ercolano, G., Cicco, P. D., & Ianaro, A. (2019) · Marine Drugs · doi:10.3390/md17010031 · Cited by 102 · see citing works

Bioactive substances of cyanobacteria and microalgae: Sources, metabolism, and anticancer mechanism insights

Bouyahya, A., Bakrim, S., Chamkhi, I., Taha, D., Omari, N. E., Mneyiy, N. E., Hachlafi, N. E., El‐Shazly, M., Khalid, A., Abdalla, A. N., et al. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115989 · Cited by 96 · see citing works

Cyanobacteria: Applications in Biotechnology

Kumar, J., Singh, D., Tyagi, M. B., & Kumar, A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814667-5.00016-7 · Cited by 85 · see citing works

Anticancer, Antiviral, Antibacterial, and Antifungal Properties in Microalgae

Dewi, I. C., Falaise, C., Hellio, C., Bourgougnon, N., & Mouget, J. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811405-6.00012-8 · Cited by 80 · see citing works

Carotenoids from Cyanobacteria: A Biotechnological Approach for the Topical Treatment of Psoriasis

Lopes, G., Clarinha, D., & Vasconcelos, V. M. (2020) · Microorganisms · doi:10.3390/microorganisms8020302 · Cited by 79 · see citing works

The anticancer effect of Huaier (Review)

Song, X., Li, Y., Zhang, H., & Yang, Q. (2015) · Oncology Reports · doi:10.3892/or.2015.3950 · Cited by 78 · see citing works

Cyanobacteria and Microalgae in the Production of Valuable Bioactive Compounds

Martínez-Francés, E., & Escudero‐Oñate, C. (2018) · InTech eBooks · doi:10.5772/intechopen.74043 · Cited by 72 · see citing works

Cyanobacteria as Natural Therapeutics and Pharmaceutical Potential: Role in Antitumor Activity and as Nanovectors

Qamar, H., Hussain, K., Soni, A., Khan, A., Hussain, T., & Chénais, B. (2021) · Molecules · doi:10.3390/molecules26010247 · Cited by 69 · see citing works

Hypotensive, hypoglycaemic and hypolipidaemic effects of bioactive compounds from microalgae and marine micro‐organisms

Zhao, C., Wu, Y., Yang, C., Liu, B., & Huang, Y. (2015) · International Journal of Food Science & Technology · doi:10.1111/ijfs.12860 · Cited by 69 · see citing works

Marine Cyanobacteria: A Source of Lead Compounds and their Clinically-Relevant Molecular Targets

Tan, L. T., & Phyo, M. Y. (2020) · Molecules · doi:10.3390/molecules25092197 · Cited by 65 · see citing works

Baltic cyanobacteria – a source of biologically active compounds

Mazur‐Marzec, H., Błaszczyk, A., Felczykowska, A., Hohlfeld, N., Kobos, J., Toruńska-Sitarz, A., Devi, P., Montalvão, S. I. G. H. M., D’Souza, L., Tammela, P., et al. (2015) · European Journal of Phycology · doi:10.1080/09670262.2015.1062563 · Cited by 64 · see citing works

Marine Peptides as Anticancer Agents: A Remedy to Mankind by Nature

Negi, B., Kumar, D., & Rawat, D. S. (2016) · Current Protein and Peptide Science · doi:10.2174/1389203717666160724200849 · Cited by 64 · see citing works

Alkynyl-Containing Peptides of Marine Origin: A Review

Chai, Q.-Y., Yang, Z., Lin, H., & Han, B. (2016) · Marine Drugs · doi:10.3390/md14110216 · Cited by 63 · see citing works

Assessment of the antioxidant and anticancer potential of different isolated strains of cyanobacteria and microalgae from soil and agriculture drain water

Senousy, H. H., Ellatif, S. A. A., & Ali, S. (2020) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-08332-z · Cited by 62 · see citing works

The Chemistry of Hapalindoles, Fischerindoles, Ambiguines, and Welwitindolinones

Bhat, V., Dave, A. H., MacKay, J. A., & Rawal, V. H. (2013) · The Alkaloids. Chemistry and biology/The alkaloids. Chemistry and biology · doi:10.1016/b978-0-12-411565-1.00002-0 · Cited by 56 · see citing works

Apoptosis as a Mechanism of the Cancer Chemopreventive Activity of Glucosinolates: a Review

Arumugam, A., & Razis, A. F. A. (2018) · Europe PMC (PubMed Central) · doi:10.22034/apjcp.2018.19.6.1439 · Cited by 56 · see citing works

Marine Cyanobacteria as Sources of Lead Anticancer Compounds: A Review of Families of Metabolites with Cytotoxic, Antiproliferative, and Antineoplastic Effects

Robles-Bañuelos, B., Durán-Riveroll, L. M., Rangel‐López, E., Pérez-López, H. I., & González‐Maya, L. (2022) · Molecules · doi:10.3390/molecules27154814 · Cited by 54 · see citing works

Cyanopeptolins with Trypsin and Chymotrypsin Inhibitory Activity from the Cyanobacterium Nostoc edaphicum CCNP1411

Mazur‐Marzec, H., Fidor, A., Cegłowska, M., Wieczerzak, E., Kropidłowska, M., Goua, M., Macaskill, J. S., & Edwards, C. (2018) · Marine Drugs · doi:10.3390/md16070220 · Cited by 53 · see citing works

Characterization of Drug-like Chemical Space for Cytotoxic Marine Metabolites Using Multivariate Methods

Jagannathan, R. (2019) · ACS Omega · doi:10.1021/acsomega.8b01764 · Cited by 53 · see citing works

Bioactive Compounds of <i>Arthrospira</i> spp. (Spirulina) with Potential Anticancer Activities: A Systematic Review

Silva, M. R. O. B. D., M. da Silva, G., Silva, A. L. F. D., Lima, L. R. A. D., Bezerra, R. P., & Marques, D. D. A. V. (2021) · ACS Chemical Biology · doi:10.1021/acschembio.1c00568 · Cited by 51 · see citing works

UV-induced DNA damage and repair: A cyanobacterial perspective

Pathak, J., Rajneesh, Singh, P. R., Häder, D. P., & Sinha, R. P. (2019) · Plant Gene · doi:10.1016/j.plgene.2019.100194 · Cited by 48 · see citing works

Dereplication of Natural Products with Antimicrobial and Anticancer Activity from Brazilian Cyanobacteria

Shishido, T. K., Popin, R. V., Jokela, J., Wahlsten, M., Fiore, M. F., Fewer, D. P., Herfindal, L., & Sivonen, K. (2019) · Toxins · doi:10.3390/toxins12010012 · Cited by 48 · see citing works

A comprehensive review of the therapeutic potential of cyanobacterial marine bioactives: Unveiling the hidden treasures of the sea

Nawaz, T., Gu, L., Fahad, S., Saud, S., Jiang, Z.-Y., Hassan, S., Harrison, M. T., Liu, K., Khan, M. A., Liu, H., et al. (2023) · Food and Energy Security · doi:10.1002/fes3.495 · Cited by 47 · see citing works

Investigation of the Anti-Prostate Cancer Properties of Marine-Derived Compounds

Fan, M., Nath, A., Tang, Y., Choi, Y., Debnath, T., Choi, E., & Kim, E. (2018) · Marine Drugs · doi:10.3390/md16050160 · Cited by 43 · see citing works

Anticancer compounds from cyanobacterium Lyngbya species: a review

Swain, S. S., Padhy, R. N., & Singh, P. K. (2015) · Antonie van Leeuwenhoek · doi:10.1007/s10482-015-0487-2 · Cited by 42 · see citing works

Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells

Freitas, S., Martins, R., Costa, M., Leão, P., Vitorino, R., Vasconcelos, V., & Urbatzka, R. (2016) · Marine Drugs · doi:10.3390/md14090158 · Cited by 37 · see citing works

Freshwater Cyanobacterial Toxins, Cyanopeptides and Neurodegenerative Diseases

Nugumanova, G., Ponomarev, E. D., Askarova, S., Fasler‐Kan, E., & Barteneva, N. S. (2023) · Toxins · doi:10.3390/toxins15030233 · Cited by 37 · see citing works

Total synthesis of calothrixins A and B via oxidative radical reaction of cyclohexenone with aminophenanthridinedione

Xu, S., Nguyen, T. H. P., Pomilio, I., Vitale, M. C., & Velu, S. E. (2014) · Tetrahedron · doi:10.1016/j.tet.2014.06.021 · Cited by 37 · see citing works

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Zhang, S., Han, L., Shi, Y., Li, X., Zhang, X., Hou, H., Lin, H., & Liu, K. (2018) · Marine Drugs · doi:10.3390/md16120473 · Cited by 37 · see citing works

Total Synthesis, Stereochemical Reassignment, and Biological Evaluation of (−)‐Lyngbyaloside B

Fuwa, H., Okuaki, Y., Yamagata, N., & Sasaki, M. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201409629 · Cited by 37 · see citing works

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Lefranc, F., Koutsaviti, A., Ioannou, E., Kornienko, A., Roussis, V., Robert Kiss, A., & Newman, D. J. (2018) · Natural Product Reports · doi:10.1039/c8np00057c · Cited by 36 · see citing works

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Humisto, A., Jokela, J., Teigen, K., Wahlsten, M., Permi, P., Sivonen, K., & Herfindal, L. (2019) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2019.03.010 · Cited by 36 · see citing works

Total Synthesis and Conformational Analysis of Apratoxin C

Masuda, Y., Suzuki, J., Onda, Y., Fujino, Y., Yoshida, M., & Doi, T. (2014) · The Journal of Organic Chemistry · doi:10.1021/jo501130b · Cited by 33 · see citing works

Microalgae in Human Health and Medicine

Basheer, S., Huo, S., Zhu, F., Qian, J., Xu, L., Cui, F., & Zou, B. (2020) · Springer eBooks · doi:10.1007/978-981-15-0169-2_5 · Cited by 33 · see citing works

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Wang, W., Yu, W., Li, G., Huang, H., Song, X., Chen, Y., & Chen, Y. (2023) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2023.215178 · Cited by 33 · see citing works

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Das, S., & Goswami, R. K. (2014) · The Journal of Organic Chemistry · doi:10.1021/jo5019798 · Cited by 33 · see citing works

Microalgae in Human Health

Nazih, H., & Bard, J. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811405-6.00010-4 · Cited by 32 · see citing works

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Konstantinou, D., Mavrogonatou, E., Zervou, S., Giannogonas, P., & Gkelis, S. (2020) · Toxins · doi:10.3390/toxins12020073 · Cited by 32 · see citing works

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Ejaz, S., Nadeem, H., Paracha, R. Z., Sarwar, S., & Ejaz, S. (2019) · BMC Chemistry · doi:10.1186/s13065-019-0631-6 · Cited by 30 · see citing works

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Rauf, A., Khalil, A. A., Khan, M., Anwar, S., Alamri, A., Alqarni, A. M., Alghamdi, A., Alshammari, F., Rengasamy, K. R. R., & Wan, C. C. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1910482 · Cited by 29 · see citing works

Fresh Water Cyanobacteria Geitlerinema sp. CCC728 and Arthrospira sp. CCC729 as an Anticancer Drug Resource

Srivastava, A., Tiwari, R., Srivastava, V. K., Singh, T. B., & Asthana, R. K. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136838 · Cited by 27 · see citing works

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Mogany, T., Swalaha, F. M., Allam, M., Mtshali, P. S., Ismail, A., Kumari, S., & Bux, F. (2018) · Microbiological Research · doi:10.1016/j.micres.2018.04.001 · Cited by 25 · see citing works

Untitled work

(2013) · Cited by 22 · see citing works

Bioactive metabolites produced by Spirulina subsalsa from the Baltic Sea

Szubert, K., Wiglusz, M., & Mazur‐Marzec, H. (2017) · Oceanologia · doi:10.1016/j.oceano.2017.11.003 · Cited by 21 · see citing works

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Blank, C. E., & Hinman, N. W. (2016) · Algal Research · doi:10.1016/j.algal.2016.02.014 · Cited by 21 · see citing works

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Barboza, G. F. D. O., Gorlach‐Lira, K., Sassi, C. F. D. C., & Sassi, R. (2017) · Revista de Biología Tropical · doi:10.15517/rbt.v65i3.29437 · Cited by 21 · see citing works

Kurahamide, a Cyclic Depsipeptide Analog of Dolastatin 13 from a Marine Cyanobacterial Assemblage of Lyngbya sp.

Iwasaki, A., Sumimoto, S., Ohno, O., Suda, S., & Suenaga, K. (2014) · Bulletin of the Chemical Society of Japan · doi:10.1246/bcsj.20140008 · Cited by 21 · see citing works

Flow cytometry as a valuable tool to study cyanobacteria:A mini-review

Poniedziałek, B., Falfushynska, H., & Rzymski, P. (2017) · Limnological Review · doi:10.1515/limre-2017-0009 · Cited by 19 · see citing works

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Semary, N. A. H. E., & Fouda, M. S. (2015) · Asian Pacific Journal of Tropical Biomedicine · doi:10.1016/j.apjtb.2015.09.004 · Cited by 18 · see citing works

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Freitas, S., Martins, R. F., Campos, A. M. O., Azevedo, J., Osório, H., Costa, M., Barros, P., Vasconcelos, V. M., & Urbatzka, R. (2016) · Toxicon · doi:10.1016/j.toxicon.2016.05.016 · Cited by 18 · see citing works

Divergent Synthesis of Revised Apratoxin E, 30-epi-Apratoxin E, and 30S/30R-Oxoapratoxin E

Mao, Z., Si, C., Liu, Y.-W., Dong, H., Wei, B., & Lin, G. (2017) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.7b01598 · Cited by 17 · see citing works

Anticancer potential and cytotoxic effect of some freshwater cyanobacteria

Karan, T., & Aydın, A. O. (2019) · Tropical Journal of Pharmaceutical Research · doi:10.4314/tjpr.v17i11.11 · Cited by 17 · see citing works

Marine natural products

Hill, R. A. (2013) · Annual Reports Section B (Organic Chemistry) · doi:10.1039/c3oc90008h · Cited by 17 · see citing works

Biotechnological potential of Neolyngbya (Cyanobacteria), a new marine benthic filamentous genus from Brazil

Caires, T. A., da Silva, A. M. S., Vasconcelos, V. M., Affe, H. M. D. J., Neta, L. C. D. S., Boness, H. V. M., Sant’Anna, C. L., & Nunes, J. M. C. (2018) · Algal Research · doi:10.1016/j.algal.2018.10.001 · Cited by 17 · see citing works

Marine-derived pipeline anticancer natural products: a review of their pharmacotherapeutic potential and molecular mechanisms

Ali‐Seyed, M., & Ayesha, S. (2021) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-021-00350-z · Cited by 16 · see citing works

Hydrobiological Aspects of Fatty Acids: Unique, Rare, and Unusual Fatty Acids Incorporated into Linear and Cyclic Lipopeptides and Their Biological Activity

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Phycocyanin attenuates skeletal muscle damage and fatigue via modulation of Nrf2 and IRS-1/AKT/mTOR pathway in exercise-induced oxidative stress in rats

Puengpan, S., Phetrungnapha, A., Sattayakawee, S., & Tunsophon, S. (2024) · PLoS ONE · doi:10.1371/journal.pone.0310138 · Cited by 16 · see citing works

Total Synthesis of Kanamienamide

Reddy, D. P., Zhang, N., Yu, Z., Wang, Z., & He, Y. (2017) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.7b01984 · Cited by 16 · see citing works

Tolyporphins L–R: Unusual Tetrapyrroles from a Brasilonema sp. of Cyanobacterium

Gurr, J. R., Dai, J., Philbin, C. S., Sartain, H. T., O’Donnell, T. J., Yoshida, W. Y., Rheingold, A. L., & Williams, P. G. (2019) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.9b01928 · Cited by 16 · see citing works

Characterization and Biotechnological Potential of Two Native Marine Microalgae Isolated from the Tunisian Coast

Mohamed, J. B., Elleuch, J., Drira, M., Esteban, M. Á., Michaud, P., Abdelkafi, S., & Fendri, I. (2021) · Applied Sciences · doi:10.3390/app11115295 · Cited by 15 · see citing works

Identification, Heterologous Expression, and Characterization of the Tolypodiol Biosynthetic Gene Cluster through an Integrated Approach

Back, D., O’Donnell, T. J., Axt, K. K., Gurr, J. R., Vanegas, J. M., Williams, P. G., & Philmus, B. J. (2023) · ACS Chemical Biology · doi:10.1021/acschembio.3c00225 · Cited by 15 · see citing works

Cyanobacteria derived compounds: Emerging drugs for cancer management

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Total Synthesis, Stereochemical Reassignment, and Biological Evaluation of (−)‐Lyngbyaloside B

Fuwa, H., Okuaki, Y., Yamagata, N., & Sasaki, M. (2014) · Angewandte Chemie · doi:10.1002/ange.201409629 · Cited by 13 · see citing works

Diversity of intertidal marine sponges from the western coast of Portugal (North-east Atlantic)

Regueiras, A., Alex, A., Costa, M., Pereira, S., & Vasconcelos, V. M. (2019) · Journal of the Marine Biological Association of the United Kingdom · doi:10.1017/s0025315419000420 · Cited by 12 · see citing works

A rapid and low-cost method for genomic DNA extraction from the cyanobacterium Synechocystis

Harrison, D. J. A., & Thompson, E. P. (2020) · Biology Methods and Protocols · doi:10.1093/biomethods/bpaa011 · Cited by 12 · see citing works

Pseudanabaena galeata CCNP1313—Biological Activity and Peptides Production

Cegłowska, M., Szubert, K., Grygier, B., Lenart, M., Plewka, J., Milewska, A., Lis, K., Szczepański, A., Chykunova, Y., Barreto-Durán, E., et al. (2022) · Toxins · doi:10.3390/toxins14050330 · Cited by 12 · see citing works

Correlation analysis for alterations of intestinal flora in hepatocellular carcinoma patients: combinatorial detection of Coriobacterium, Atopobium, Coprococcus and Veillonella dispar may be a new method for HCC diagnosis

Xu, W., Jiang, Y., Tao, J., Liu, Y., Xia, Y., Chen, C., & Jiang, X. (2023) · Journal of Medical Microbiology · doi:10.1099/jmm.0.001713 · Cited by 12 · see citing works

First evidence of Halomicronema metazoicum (Cyanobacteria) free-living on Posidonia oceanica leaves

Ruocco, N., Mutalipassi, M., Pollio, A., Costantini, S., Costantini, M., & Zupo, V. (2018) · PLoS ONE · doi:10.1371/journal.pone.0204954 · Cited by 12 · see citing works

Microalgal Systematics

Sexton, J. P., & Lomas, M. W. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811405-6.00004-9 · Cited by 12 · see citing works

Can marine‐derived fungus Neosartorya siamensis KUFA 0017 extract and its secondary metabolites enhance antitumor activity of doxorubicin? An in vitro survey unveils interactions against lung cancer cells

Ramos, A. A., Castro‐Carvalho, B., Prata‐Sena, M., Malhão, F., Buttachon, S., Dethoup, T., Kijjoa, A., & Rocha, E. (2019) · Environmental Toxicology · doi:10.1002/tox.22886 · Cited by 11 · see citing works

Enhancement of Anticancer, Antibacterial, and Acetylcholinesterase Inhibition Activities from Oscillatoria sancta under Starvation Conditions

Touliabah, H. E.-S., & Refaay, D. A. (2023) · Water · doi:10.3390/w15040664 · Cited by 11 · see citing works

Occurrence of aetokthonotoxin producer in natural samples – A PCR protocol for easy detection

Štenclová, L., Wilde, S. B., Schwark, M., Cullen, J. L., McWhorter, S. A., Niedermeyer, T. H. J., Henderson, W. M., & Mareš, J. (2023) · Harmful Algae · doi:10.1016/j.hal.2023.102425 · Cited by 11 · see citing works

Toward the total synthesis of a lagunamide B analogue

Pal, S., & Chakraborty, T. K. (2014) · Tetrahedron Letters · doi:10.1016/j.tetlet.2014.04.079 · Cited by 11 · see citing works

Bacterial diversity of the outflows of a Polichnitos (Lesvos, Greece) hot spring, laboratory studies of a Cyanobacterium sp. strain and potential medical applications

Mizerakis, P., Stathopoulou, P. M., Tsiamis, G., Baeshen, M. N., Mahyoub, J. A., Elazzazy, A. M., Bellou, S., Sakoulogeorga, E., Triantaphyllidou, I., Mazioti, T., et al. (2017) · Annals of Microbiology · doi:10.1007/s13213-017-1293-z · Cited by 11 · see citing works

Total Synthesis of the Highly N-Methylated Peptides Carmabin A and Dragomabin

Ye, B., Jiang, P., Zhang, T., Sun, Y., Hao, X., Cui, Y., Wang, L., & Chen, Y. (2018) · Marine Drugs · doi:10.3390/md16090338 · Cited by 10 · see citing works

Prophyletic origin of algae as potential repository of anticancer compounds

Tripathi, R., Shalini, R., & Singh, R. K. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-821710-8.00007-2 · Cited by 10 · see citing works

Cyanobacterial peptides with respect to anticancer activity: Structural and functional perspective

Ahmad, I. Z., Parvez, S., & Tabassum, H. (2020) · Studies in natural products chemistry · doi:10.1016/b978-0-12-819483-6.00010-2 · Cited by 10 · see citing works

Depsipeptides Targeting Tumor Cells: Milestones from In Vitro to Clinical Trials

Trinidad-Calderón, P. A., Varela-Chinchilla, C. D., & García‐Lara, S. (2023) · Molecules · doi:10.3390/molecules28020670 · Cited by 9 · see citing works

Imminent Angiotensin-converting Enzyme Inhibitor from Microbial Source for Cancer Therapy

Ebrahimi, L., Ai, J., Alizadeh, A. A., & Shariaty, M. (2017) · International Journal of Preventive Medicine · doi:10.4103/ijpvm.ijpvm_324_16 · Cited by 9 · see citing works

Trends in Cyanobacteria: a contribution to systematics and biodiversity studies

Hentschke, G. S., & Gama, W. A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821491-6.00001-6 · Cited by 9 · see citing works

Biomedical potential of cyanobacteria and algae

Ughy, B., Nagy, C. I., & Kós, P. B. (2015) · Repository of the Academy's Library (Library of the Hungarian Academy of Sciences) · Cited by 9 · see citing works

Total synthesis and stereochemical determination of yoshinone A

Shinomiya, S., Iwasaki, A., Ohno, O., & Suenaga, K. (2016) · Phytochemistry · doi:10.1016/j.phytochem.2016.10.005 · Cited by 9 · see citing works

Omega-7 producing alkaliphilic diatom Fistulifera sp. (Bacillario-phyceae) from Lake Okeechobee, Florida

Berthold, D. E., Rosa, N. D. L., Engene, N., Jayachandran, K., Gantar, M., Laughinghouse, H. D., & Shetty, K. G. (2020) · ALGAE · doi:10.4490/algae.2020.35.12.16 · Cited by 9 · see citing works

Marine Cyanobacteria Compounds with Anticancer Properties: Implication of Apoptosis

Martins, M. D. R., & Costa, M. (2014) · Springer eBooks · doi:10.1007/978-3-319-07145-9_29 · Cited by 9 · see citing works

Screening of cyanobacterial extracts for apoptotic inducers: a combined approach of caspase-3/7 homogeneous assay and time-lapse microscopy

Voráčová, K., Paichlová, J., Vicková, K., & Hrouzek, P. (2017) · Journal of Applied Phycology · doi:10.1007/s10811-017-1122-6 · Cited by 8 · see citing works

A new active peptide from Neptunea arthritica cumingii exerts protective effects against gentamicin-induced sensory-hair cell injury in zebrafish

Zhang, S., Gao, Y., He, Q., Zhang, Y. L., Han, L., Jin, M., Liu, T., Liu, K., & Sun, C. (2019) · Drug and Chemical Toxicology · doi:10.1080/01480545.2019.1665680 · Cited by 7 · see citing works

Biological Activity and Stability of Aeruginosamides from Cyanobacteria

Cegłowska, M., Kwiecień, P., Szubert, K., Brzuzan, P., Florczyk, M., Edwards, C., Kosakowska, A., & Mazur‐Marzec, H. (2022) · Marine Drugs · doi:10.3390/md20020093 · Cited by 7 · see citing works

Marine Cyanobacteria

Le, P. U., Vo, T., & Kim, S. (2020) · Wiley eBooks · doi:10.1002/9781119143802.ch97 · Cited by 7 · see citing works

Cyanobacteria as a Source of Bioactive Compounds with Anticancer, Antibacterial, Antifungal, and Antiviral Activities: A Review

(2023) · Microbial Bioactives · doi:10.25163/microbbioacts.617330 · Cited by 6 · see citing works

Phytotoxic, cytogenotoxic, and insecticidal activities of compounds from extracts of freshwater Lyngbya sp

da Silva, R. M. G., AMÂNCIO, I. F. N., de Andrade, A. R., dos Santos, V. H. M., Santiago, P. S., Granero, F. O., Figueiredo, C. C. M., & Silva, L. P. (2022) · Journal of Toxicology and Environmental Health · doi:10.1080/15287394.2022.2102100 · Cited by 6 · see citing works

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Srivastava, A., & Raghuwanshi, R. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-821710-8.00010-2 · Cited by 6 · see citing works

Synthetic studies towards lagunamide C: Polyketide assembly investigations

Fatino, A., Weese, C., Valdez, S., Jiménez-Somarribas, A., & Rafferty, R. J. (2018) · Tetrahedron Letters · doi:10.1016/j.tetlet.2017.12.083 · Cited by 6 · see citing works

Marine Cyanobacteria Compounds with Anticancer Properties: Implication of Apoptosis

Martins, M. D. R., & Costa, M. (2014) · Springer eBooks · doi:10.1007/978-3-319-07145-9_29 · Cited by 9 · see citing works

Cyanobacteria derived compounds: Emerging drugs for cancer management

Shahid, A., Khurshid, M., Aslam, B., Muzammil, S., Mehwish, H. M., Rajoka, M. S. R., Hayat, H. F., Sarfraz, M. H., Razzaq, M. K., Nisar, M. A., et al. (2021) · Journal of Basic Microbiology · doi:10.1002/jobm.202100459 · Cited by 15 · see citing works

Anticancer Drug Development from Cyanobacteria

Mandal, S., & Rath, J. (2014) · SpringerBriefs in pharmaceutical science & drug development · doi:10.1007/978-3-319-12009-6_4 · Cited by 4 · see citing works

Insights into the potential of picoplanktonic marine cyanobacteria strains for cancer therapies – Cytotoxic mechanisms against the RKO colon cancer cell line

Freitas, S., Martins, R. F., Campos, A. M. O., Azevedo, J., Osório, H., Costa, M., Barros, P., Vasconcelos, V. M., & Urbatzka, R. (2016) · Toxicon · doi:10.1016/j.toxicon.2016.05.016 · Cited by 18 · see citing works

Exploring Bioactive Properties of Marine Cyanobacteria Isolated from the Portuguese Coast: High Potential as a Source of Anticancer Compounds

Costa, M., Garcia, M. P., Costa‐Rodrigues, J., Costa, M., Ribeiro, M., Fernandes, M. H., Barros, P., Barreiro, A., Vasconcelos, V. M., & Martins, R. F. (2013) · Marine Drugs · doi:10.3390/md12010098 · Cited by 77 · see citing works