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Bioactives from Agri-Food Wastes: Present Insights and Future Challenges
Open accessAbstract
Sustainable utilization of agri-food wastes and by-products for producing value-added products (for cosmetic, pharmaceutical or food industrial applications) provides an opportunity for earning additional income for the dependent industrial sector. Besides, effective valorisation of wastes/by-products can efficiently help in reducing environmental stress by decreasing unwarranted pollution. The major focus of this review is to provide comprehensive information on valorisation of agri-food wastes and by-products with focus laid on bioactive compounds and bioactivity. The review covers the bioactives identified from wastes and by-products of plants (fruits, exotic fruits, vegetables and seeds), animals (dairy and meat) and marine (fish, shellfish seaweeds) resources. Further, insights on the present status and future challenges of sustainably utilizing agri-food wastes/by-products for value addition will be highlighted.
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![Figure 1 Graphical extract indicating valorisation of food waste based on the concept of biorefinery (reproduced from [7] with permission from Elsevier License number; 4681870689768; dt. Oct 04, 2019)](/paper-figures/2eb26dfa03ae4af690a0f595e850bf6f/bioactives-from-agri-food-wastes-present-insights-and-future-challenges-figure-1.jpg)
![Figure 2 An integrated biorefinery model for fruit processing waste (FPW). As per the authors, this model is based on ‘fractionation strategy’ to improve the cost-efficiency of FPW valorization. Recovery of lipids from fruit kernels can be followed by extraction of proteins and polyphenols. Peels and pomace can be used for the recovery of soluble dietary fibers like pectin and polyphenols in one step extraction followed by alcoholic precipitation (reproduced from [8] with permission from Elsevier License number 4681860844753; dt. Oct 04, 2019).](/paper-figures/6dda866959e34520a8d126b515683103/bioactives-from-agri-food-wastes-present-insights-and-future-challenges-figure-2.jpg)

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“Unfortunately, residues end up most often in landfills, significantly contributing to global pollution levels by producing significant amounts of methane, which consequently leads to greenhouse gas emissions [52,53,58,64,65].”
From Use of Waste from the Food Industry and Applications of the Fermentation Process to Create Sustainable Cosmetic Products: A Review (2024) · cites this paper as [65]
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“As a result of biotechnological transformations of waste from the food industry, various products such as biofuels, biomass, biofertilizers, biosorbents, and value-added components can be produced via anaerobic digestion, fermentation, and composting technologies [64,65,72].”
From Use of Waste from the Food Industry and Applications of the Fermentation Process to Create Sustainable Cosmetic Products: A Review (2024) · cites this paper as [65]
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“In the non-edible parts of fruits (peels or twigs), the content of bioactive compounds, such as polyphenols, is often higher than in the edible parts (pulp) [65,73].”
From Use of Waste from the Food Industry and Applications of the Fermentation Process to Create Sustainable Cosmetic Products: A Review (2024) · cites this paper as [65]
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“Bioactive compounds isolated from animal-based waste include mainly peptides.”
From Use of Waste from the Food Industry and Applications of the Fermentation Process to Create Sustainable Cosmetic Products: A Review (2024) · cites this paper as [65]
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“In the marine sector, bioactives could be obtained from fish and shellfish processing, as well as from seaweeds [65,142,143].”
From Use of Waste from the Food Industry and Applications of the Fermentation Process to Create Sustainable Cosmetic Products: A Review (2024) · cites this paper as [65]
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Self-citation
Metadata
- Authors
- Ben-Othman, S., Jõudu, I., & Bhat, R.
- Affiliations
- ERA Chair for Food (By-) Products Valorisation Technologies of the Estonian University of Life Sciences (VALORTECH), Estonian University of Life Sciences, Fr.R.Kreutzwaldi 56/5, 51006 Tartu, Estonia
- Estonian University of Life Sciences (EE)
- Corresponding author
- Bhat, Rajeev
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2020-01-24
- Volume
- 25
- Issue
- 3
- Pages
- 510
- ISSN
- 1420-3049 (ISSN-L)
- PMC
- PMC7037811
- OpenAlex
- W3002753355
- Cited by
- 482
- References
- 175
- Citations by year
- 2026: 47 · 2025: 84 · 2024: 92 · 2023: 93 · 2022: 80 · 2021: 58 · 2020: 28
- FWCI
- 5.63
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Molecules (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- EMU DSpace (submittedVersion, cc-by)
- Funders
- Horizon 2020 (810630)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
- Life Sciences › Agricultural and Biological Sciences › Food Science › Protein Hydrolysis and Bioactive Peptides
- Keywords
- bioactive compounds, biological activity, value-added products, waste by-products, fruit waste, vegetable waste, dairy by-products, meat by-products, seaweed, sustainable waste utilization, pollution reduction
- MeSH terms
- Fruit, Refuse Disposal, Vegetables, Waste Products
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