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Role of Monoamine Oxidase Activity in Alzheimer’s Disease: An Insight into the Therapeutic Potential of Inhibitors
Open accessAbstract
Despite not being utilized as considerably as other antidepressants in the therapy of depression, the monoamine oxidase inhibitors (MAOIs) proceed to hold a place in neurodegeneration and to have a somewhat broad spectrum in respect of the treatment of neurological and psychiatric conditions. Preclinical and clinical studies on MAOIs have been developing in recent times, especially on account of rousing discoveries manifesting that these drugs possess neuroprotective activities. The altered brain levels of monoamine neurotransmitters due to monoamine oxidase (MAO) are directly associated with various neuropsychiatric conditions like Alzheimer’s disease (AD). Activated MAO induces the amyloid-beta (Aβ) deposition via abnormal cleavage of the amyloid precursor protein (APP). Additionally, activated MAO contributes to the generation of neurofibrillary tangles and cognitive impairment due to neuronal loss. No matter the attention of researchers on the participation of MAOIs in neuroprotection has been on monoamine oxidase-B (MAO-B) inhibitors, there is a developing frame of proof indicating that monoamine oxidase-A (MAO-A) inhibitors may also play a role in neuroprotection. The therapeutic potential of MAOIs alongside the complete understanding of the enzyme’s physiology may lead to the future advancement of these drugs.
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McKhann, G. M., Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, C. R., Kawas, C. H., Klunk, W. E., Koroshetz, W. J., Manly, J. J., Mayeux, R., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.005 · Cited by 18,657
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
Bedard, K., & Krause, K.-H. (2007) · Physiological Reviews · doi:10.1152/physrev.00044.2005 · Cited by 6,989
2016 Alzheimer's disease facts and figures
Alzheimer's Association (2016) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2016.03.001 · Cited by 5,069
Molecular dissection of reactive astrogliosis and glial scar formation
Sofroniew, M. V. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2009.08.002 · Cited by 2,594
A Controlled Trial of Selegiline, Alpha-Tocopherol, or Both as Treatment for Alzheimer's Disease
Sano, M., Ernesto, C., Thomas, R. G., Klauber, M. R., Schafer, K., Grundman, M., Woodbury, P., Growdon, J., Cotman, C. W., Pfeiffer, E., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704243361704 · Cited by 2,380
2015 Alzheimer's disease facts and figures
Alzheimer's Association (2015) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2015.02.003 · Cited by 1,635
The therapeutic potential of monoamine oxidase inhibitors
Youdim, M. B. H., Edmondson, D., & Tipton, K. F. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1883 · Cited by 1,363
Wyss-Coray (2006) · doi:10.1038/nm1484 · Cited by 1,284
Studies on free radicals, antioxidants, and co-factors.
Rahman, K. (2007) · PubMed Central · Cited by 995
The GABAergic deficit hypothesis of major depressive disorder
Luscher, B., Shen, Q., & Sahir, N. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.120 · Cited by 934
Aldehyde Sources, Metabolism, Molecular Toxicity Mechanisms, and Possible Effects on Human Health
O'Brien, P. J., Siraki, A. G., & Shangari, N. (2005) · Critical Reviews in Toxicology · doi:10.1080/10408440591002183 · Cited by 738
Lombardo, I., Ramaswamy, G., Piscitelli, S. C., & Friedhoff, L. (2015) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2015.08.154 · Cited by 656
Rascol, O., Brooks, D., Melamed, E., Oertel, W., Poewe, W., Stocchi, F., & Tolosa, E. (2005) · The Lancet · doi:10.1016/s0140-6736(05)71083-7 · Cited by 641
Son, S.-Y., Ma, J., Kondou, Y., Yoshimura, M., Yamashita, E., & Tsukihara, T. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0710626105 · Cited by 623
Binda, C., Wang, J., Pisani, L., Caccia, C., Carotti, A., Salvati, P., Edmondson, D. E., & Mattevi, A. (2007) · Journal of Medicinal Chemistry · doi:10.1021/jm070677y · Cited by 607
De Colibus, L., Li, M., Binda, C., Lustig, A., Edmondson, D. E., & Mattevi, A. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505975102 · Cited by 527
Molecular Mechanisms of Acrolein Toxicity: Relevance to Human Disease
Moghe, A., Ghare, S., Lamoreau, B., Mohammad, M., Barve, S., McClain, C., & Joshi-Barve, S. (2015) · Toxicological Sciences · doi:10.1093/toxsci/kfu233 · Cited by 511
Carter, S. F., Schöll, M., Almkvist, O., Wall, A., Engler, H., Långström, B., & Nordberg, A. (2012) · Journal of Nuclear Medicine · doi:10.2967/jnumed.110.087031 · Cited by 442
Inflammatory process in Alzheimer's Disease
Meraz-Ríos, M. A., Toral-Rios, D., Franco-Bocanegra, D., Villeda-Hernández, J., & Campos-Peña, V. (2013) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2013.00059 · Cited by 427
(2005) · Archives of Neurology · doi:10.1001/archneur.62.2.241 · Cited by 418
Saura, J., Luque, J. M., Cesura, A. M., Prada, M. D., Chan-Palay, V., Huber, G., Löffler, J., & Richards, J. G. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90311-5 · Cited by 382
The importance of norepinephrine in depression
Briley, M., & Chantal, M. (2011) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s19619 · Cited by 373
Oxidative Stress and Cardiovascular Risk: Obesity, Diabetes, Smoking, and Pollution
Niemann, B., Rohrbach, S., Miller, M. R., Newby, D. E., Fuster, V., & Kovacic, J. C. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.05.043 · Cited by 353
Marchitti, S. A., Deitrich, R. A., & Vasiliou, V. (2007) · Pharmacological Reviews · doi:10.1124/pr.59.2.1 · Cited by 280
Monoamine Oxidase-B Inhibition in Alzheimer's Disease
Riederer, P. (2004) · NeuroToxicology · doi:10.1016/s0161-813x(03)00106-2 · Cited by 254
Cohen, S. M., Tsien, R. W., Goff, D. C., & Halassa, M. M. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2014.12.026 · Cited by 232
Schedin-Weiss, S., Inoue, M., Hromadkova, L., Teranishi, Y., Yamamoto, N. G., Wiehager, B., Bogdanovic, N., Winblad, B., Sandebring-Matton, A., Frykman, S., et al. (2017) · Alzheimer's Research & Therapy · doi:10.1186/s13195-017-0279-1 · Cited by 230
Oxidation of amines by flavoproteins
Fitzpatrick, P. F. (2010) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2009.07.019 · Cited by 219
Park, J.-H., Ju, Y. H., Choi, J. W., Song, H. J., Jang, B. K., Woo, J., Chun, H., Kim, H. J., Shin, S. J., Yarishkin, O., et al. (2019) · Science Advances · doi:10.1126/sciadv.aav0316 · Cited by 216
Monoamine oxidase inhibitors: Promising therapeutic agents for Alzheimer’s disease (Review)
CAI, Z. (2014) · Molecular Medicine Reports · doi:10.3892/mmr.2014.2040 · Cited by 212
Gulyás, B., Pavlova, E., Kása, P., Gulya, K., Bakota, L., Várszegi, S., Keller, É., Horváth, M. C., Nag, S., Hermecz, I., et al. (2011) · Neurochemistry International · doi:10.1016/j.neuint.2010.10.013 · Cited by 202
Monoamine oxidase-B inhibitors in the treatment of Alzheimers disease
Thomas, T. (2000) · Neurobiology of Aging · doi:10.1016/s0197-4580(00)00100-7 · Cited by 201
Demougeot, C., Garnier, P., Mossiat, C., Bertrand, N., Giroud, M., Beley, A., & Marie, C. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00285.x · Cited by 194
Balu, D. T., Hoshaw, B. A., Malberg, J. E., Rosenzweig-Lipson, S., Schechter, L. E., & Lucki, I. (2008) · Brain Research · doi:10.1016/j.brainres.2008.03.023 · Cited by 194
Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease
Bradley, M. A., Markesbery, W. R., & Lovell, M. A. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.02.016 · Cited by 193
Dwivedi, Y., Rizavi, H. S., & Pandey, G. N. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.12.058 · Cited by 192
Nutraceuticals in Neurological Disorders
Makkar, R., Behl, T., Bungau, S., Zengin, G., Mehta, V., Kumar, A., Uddin, M. S., Ashraf, G. M., Abdel-Daim, M. M., Arora, S., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21124424 · Cited by 181
Self-citationPrivileged scaffolds as MAO inhibitors: Retrospect and prospects
Tripathi, A. C., Upadhyay, S., Paliwal, S., & Saraf, S. K. (2018) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2018.01.003 · Cited by 170
Parkinson Study Group (1996) · Annals of Neurology · doi:10.1002/ana.410390106 · Cited by 170
Hydrogen Peroxide Produced by Mitochondrial Monoamine Oxidase Catalysis: Biological Implications
Edmondson, D. (2014) · Current Pharmaceutical Design · doi:10.2174/13816128113190990406 · Cited by 168
Selegiline for Alzheimer's disease
Birks, J., & Flicker, L. (2003) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000442 · Cited by 162
on behalf of the CAN-BIND Investigator Team, Lam, R. W. M., Milev, R. V., Rotzinger, S., Andreazza, A. C., Blier, P., Brenner, C. A., Daskalakis, Z. J., Dharsee, M., Downar, J. H., et al. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0785-x · Cited by 155
Weinreb, O., Amit, T., Bar‐Am, O., & Youdim, M. B. H. (2012) · Current Drug Targets · doi:10.2174/138945012799499794 · Cited by 154
Foerster, B. R., Pomper, M. G., Callaghan, B. C., Petrou, M., Edden, R. A. E., Mohamed, M. A., Welsh, R. C., Carlos, R. C., Barker, P. B., & Feldman, E. L. (2013) · JAMA Neurology · doi:10.1001/jamaneurol.2013.234 · Cited by 150
Elhelaly, A. E., Albasher, G. I., Alfarraj, S. A., Almeer, R., Bahbah, E. I., Fouda, M. M. A., BUNGAU, S. G., Aleya, L., & Abdel‐Daim, M. M. (2019) · Environmental Science and Pollution Research · doi:10.1007/s11356-019-06660-3 · Cited by 146
Self-citationWang, L., Esteban, G., Ojima, M., Bautista‐Aguilera, Ó. M., Inokuchi, T., Moraleda, I., Iriepa, I., Samadi, A., Youdim, M. B. H., Romero, A., et al. (2014) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2014.04.078 · Cited by 143
Kumar, B., Sheetal, S., Mantha, A. K., & Kumar, V. (2016) · RSC Advances · doi:10.1039/c6ra00302h · Cited by 139
Origins of Serum Semicarbazide-Sensitive Amine Oxidase
Stolen, C., Yegutkin, G. G., Kurkijärvi, R., Bono, P., Alitalo, K. K., & Jalkanen, S. (2004) · Circulation Research · doi:10.1161/01.res.0000134630.68877.2f · Cited by 138
Donepezil Use in Alzheimer Disease
Barner, E. L., & Gray, S. L. (1998) · Annals of Pharmacotherapy · doi:10.1345/aph.17150 · Cited by 137
Novaroli, L., Reist, M., Favre, E., Carotti, A., Catto, M., & Carrupt, P. (2005) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2005.06.043 · Cited by 135
Rasagiline alone and in combination with riluzole prolongs survival in an ALS mouse model
Waibel, S., Reuter, A., Malessa, S., Blaugrund, E., & Ludolph, A. C. (2004) · Journal of Neurology · doi:10.1007/s00415-004-0481-5 · Cited by 134
Chen, K., Maley, J., & Yu, P. H. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04181.x · Cited by 131
Conventional and new antidepressant drugs in the elderly
Gareri, P., Falconi, U., Fazio, P. D., & Sarro, G. D. (2000) · Progress in Neurobiology · doi:10.1016/s0301-0082(99)00050-7 · Cited by 125
Ramsay, R. R. (2012) · Current Topics in Medicinal Chemistry · doi:10.2174/156802612805219978 · Cited by 121
Early and persistent alterations in prefrontal cortex MAO A and B in Alzheimer's disease
Kennedy, B. P., Ziegler, M. G., Alford, M. F., Hansen, L. A., Thal, L. J., & Masliah, E. (2003) · Journal of Neural Transmission · doi:10.1007/s00702-003-0828-6 · Cited by 116
Monoamine Oxidase and Mitochondrial Respiration
Cohen, G., & Kesler, N. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0732310.x · Cited by 115
Avila-Muñoz, E., & Arias, C. (2014) · Ageing Research Reviews · doi:10.1016/j.arr.2014.07.004 · Cited by 114
Kim, D., Baik, S. H., Kang, S., Cho, S. W., Bae, J., Cha, M.-Y., Sailor, M. J., Mook‐Jung, I., & Ahn, K. H. (2016) · ACS Central Science · doi:10.1021/acscentsci.6b00309 · Cited by 112
Lipids' peroxidation markers in Alzheimer's disease and vascular dementia
Gustaw‐Rothenberg, K., Kowalczuk, K., & Stryjecka‐Zimmer, M. (2009) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/j.1447-0594.2009.00571.x · Cited by 109
Albasher, G. I., Abdel‐Daim, M. M., Almeer, R., Ibrahim, K. A., Hamza, R. Z., BUNGAU, S. G., & Aleya, L. (2019) · Environmental Science and Pollution Research · doi:10.1007/s11356-019-07344-8 · Cited by 105
Self-citationEmilsson, L., Saetre, P., Balciuniene, J., Castensson, A., Cairns, N. J., & JAZIN, E. E. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(02)00307-5 · Cited by 102
Vascular adhesion protein-1: Role in human pathology and application as a biomarker
Pannecoeck, R., Serruys, D., Benmeridja, L., Delanghe, J., van Geel, N., Speeckaert, R., & Speeckaert, M. M. (2015) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408363.2015.1050714 · Cited by 99
The discovery of antidepressants: A winding path
Pletscher, A. (1991) · Cellular and Molecular Life Sciences · doi:10.1007/bf02041242 · Cited by 99
Selegiline: a molecule with innovative potential
Tábi, T., Vécsei, L., Youdim, M. B. H., Riederer, P. F., & Szökő, É. (2019) · Journal of Neural Transmission · doi:10.1007/s00702-019-02082-0 · Cited by 99
Potential Role of Acrolein in Neurodegeneration and in Alzheimers Disease
Nam, D. T., Arseneault, M., Murthy, V., & Ramassamy, C. (2010) · Current Molecular Pharmacology · doi:10.2174/1874-470211003020066 · Cited by 97
Lipid peroxidation products and their role in neurodegenerative diseases
Taso, O. S., Philippou, Α., Moustogiannis, A., Zevolis, E., & Koutsilieris, M. (2019) · Annals of Research Hospitals · doi:10.21037/arh.2018.12.02 · Cited by 97
Jossan, S. S., Gillberg, P., Gottfries, C. G., Karlsson, I., & Oreland, L. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90098-9 · Cited by 95
Cochet, M., Donneger, R., Cassier, E., Gaven, F., Lichtenthaler, S., Marin, P., Bockaert, J., Dumuis, A., & Claeysen, S. (2013) · ACS Chemical Neuroscience · doi:10.1021/cn300095t · Cited by 92
Alleviation of Drugs and Chemicals Toxicity: Biomedical Value of Antioxidants
Abdel‐Daim, M. M., Abo‐EL‐Sooud, K., Aleya, L., BUNGAU, S. G., Najda, A., & Saluja, R. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/6276438 · Cited by 92
Self-citationMa, Q., Manaenko, A., Khatibi, N. H., Chen, W., Zhang, J. H., & Tang, J. (2010) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2010.167 · Cited by 91
Borroni, E., Bohrmann, B., Grueninger, F., Prinssen, E. P. M., Navé, S., Loetscher, H., Chinta, S. J., Rajagopalan, S., Rane, A., Siddiqui, A., et al. (2017) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.117.241653 · Cited by 90
Acrolein induces Alzheimer's disease-like pathologies in vitro and in vivo
Huang, Y., Jin, M.-H., Pi, R., Zhang, J., Ouyang, Y., Chao, X., Chen, M.-H., Liu, P., Yu, J., Ramassamy, C., et al. (2013) · Toxicology Letters · doi:10.1016/j.toxlet.2012.12.023 · Cited by 89
Unzeta, M., Solé, M., Boada, M., & Hernández‐Guillamón, M. (2007) · Journal of Neural Transmission · doi:10.1007/s00702-007-0701-0 · Cited by 88
Stumm, R. K., Culmsee, C., Schäfer, M. K.-H., Krieglstein, J., & Weihe, E. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-03-00798.2001 · Cited by 85
Does phenylethylamine act as an endogenous amphetamine in some patients?
Janssen, P. A. J., Leysen, J. E., Megens, A. A. H. P., & Awouters, F. H. L. (1999) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145799001522 · Cited by 84
Burke, W. J., Li, S. W., Schmitt, C. A., Xia, P., Chung, H. D., & Gillespie, K. N. (1999) · Brain Research · doi:10.1016/s0006-8993(98)01211-6 · Cited by 83
Potter, L. E., Paylor, J. W., Suh, J. S., Tenorio, G., Caliaperumal, J., Colbourne, F., Baker, G. B., Winship, I. R., & Kerr, B. J. (2016) · Journal of Neuroinflammation · doi:10.1186/s12974-016-0609-4 · Cited by 82
Linking lipid peroxidation and neuropsychiatric disorders: focus on 4-hydroxy-2-nonenal
Romano, A., Serviddio, G., Calcagnini, S., Villani, R., Giudetti, A. M., Cassano, T., & Gaetani, S. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.12.046 · Cited by 79
Streit (2010) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2010.00022 · Cited by 76
Singh, I. N., Gilmer, L. K., Miller, D. M., Cebak, J. E., Wang, J. A., & Hall, E. D. (2013) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2012.211 · Cited by 76
Altered GABAergic Signaling in Brain Disease at Various Stages of Life
Kim, Y. S., & Yoon, B. (2017) · Experimental Neurobiology · doi:10.5607/en.2017.26.3.122 · Cited by 76
Methylglyoxal Induces Tau Hyperphosphorylation via Promoting AGEs Formation
Li, X., Xie, J., Jiang, X., Lv, B.-L., Cheng, X., Du, L., Zhang, J. Y., Wang, J., & Zhou, X. (2012) · NeuroMolecular Medicine · doi:10.1007/s12017-012-8191-0 · Cited by 74
Weinstock, M., Gorodetsky, E. K., Poltyrev, T., Gross, A., Sagi, Y., & Youdim, M. B. H. (2003) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(03)00053-8 · Cited by 72
Zheng, H., Amit, T., Bar‐Am, O., Fridkin, M., Youdim, M. B. H., & Mandel, S. A. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-120013 · Cited by 63
Discovery of monoamine oxidase inhibitors by medicinal chemistry approaches
Hong, R.-Y., & Li, X. (2018) · MedChemComm · doi:10.1039/c8md00446c · Cited by 63
A “cure” for Parkinson's disease: Can neuroprotection be proven with current trial designs?
Clarke, C. E. (2004) · Movement Disorders · doi:10.1002/mds.20057 · Cited by 59
Mück‐Šeler, D., Presečki, P., Mimica, N., Mustapić, M., Pivac, N., Perhoč, A. B., Erjavec, G. N., & Folnegović-Šmalc, V. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.07.004 · Cited by 58
Poltyrev, T., Gorodetsky, E. K., Bejar, C., Schorer-Apelbaum, D., & Weinstock, M. (2005) · Psychopharmacology · doi:10.1007/s00213-005-2229-z · Cited by 56
Sinem, F., Konukoğlu, D., Gokhan, E., Melda, B., Orhan, Y., & Filiz, M. (2010) · Current Alzheimer Research · doi:10.2174/156720510791383822 · Cited by 54
On the formation and nature of the imidazoline I2 binding site on human monoamine oxidase-B
McDonald, G. R., Olivieri, A., Ramsay, R. R., & Holt, A. (2010) · Pharmacological Research · doi:10.1016/j.phrs.2010.09.001 · Cited by 53
Anti-epileptic drugs as possible neuroprotectants in cerebral ischemia
Leker, R. R., & Neufeld, M. Y. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(03)00170-x · Cited by 52
Weinreb, O., Mandel, S. A., Bar‐Am, O., & Amit, T. (2011) · Journal of Neural Transmission · doi:10.1007/s00702-011-0597-6 · Cited by 51
Dhull, D. K., Jindal, A., Dhull, R. K., Aggarwal, S., Bhateja, D., & Padi, S. S. V. (2011) · Journal of Molecular Neuroscience · doi:10.1007/s12031-011-9583-6 · Cited by 50
Quartey, M. O., Nyarko, J. N. K., Pennington, P. R., Heistad, R. M., Klassen, P. C., Baker, G. B., & Mousseau, D. D. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00419 · Cited by 49
Jarnicki, A., Schilter, H. C., Liu, G., Wheeldon, K., Essilfie, A., Foot, J. S., Yow, T. T., Jarolimek, W., & Hansbro, P. M. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13573 · Cited by 48
Pharmacotherapy of social anxiety disorder
Schneier, F. R. (2011) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2011.534983 · Cited by 41
Biogenic aldehyde-mediated mechanisms of toxicity in neurodegenerative disease
Cagle, B. S., Crawford, R. A., & Doorn, J. A. (2018) · Current Opinion in Toxicology · doi:10.1016/j.cotox.2018.12.002 · Cited by 41
Kumagae, Y., Matsui, Y., & Iwata, N. (1991) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.55.121 · Cited by 40
Benefit of inhibiting SSAO in relapsing experimental autoimmune encephalomyelitis
O’Rourke, A. M., Wang, E. Y., Salter–Cid, L., Huang, L. Y., Miller, A., Podar, E. M., Gao, H., Jones, D. S., & Linnik, M. D. (2007) · Journal of Neural Transmission · doi:10.1007/s00702-007-0699-3 · Cited by 39
Antioxidant Effect of Phenelzine on MPP+-Induced Cell Viability Loss in Differentiated PC12 Cells
Lee, C. S., Han, E. S., & Lee, W. B. (2003) · Neurochemical Research · doi:10.1023/a:1026119708124 · Cited by 33
Horváth, Á. I., Menghis, A., Botz, B., Borbély, É., Kemény, Á., Tékus, V., Csepregi, J. Z., Mócsai, A., Juhász, T., Zákány, R., et al. (2017) · Scientific Reports · doi:10.1038/srep39863 · Cited by 33
Baker, G. B., Matveychuk, D., MacKenzie, E. M., Holt, A., Wang, Y., & Kar, S. (2019) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2019.03.003 · Cited by 33
An Intensified Acrolein Exposure Can Affect Memory and Cognition in Rat
Khoramjouy, M., Naderi, N., Kobarfard, F., Heidarli, E., & Faizi, M. (2020) · Neurotoxicity Research · doi:10.1007/s12640-020-00278-x · Cited by 33
García-Fuster, M. J., & García-Sevilla, J. A. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4342-6 · Cited by 32
Li, R., Sahu, S. S., & Schachner, M. (2018) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2018.05.013 · Cited by 30
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Chan‐Palay, V., Höchli, M., Savaskan, E., & Hungerecker, G. (1993) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000107290 · Cited by 25
Gal, S., Abassi, Z. A., & Youdim, M. B. H. (2009) · Neurotoxicity Research · doi:10.1007/s12640-009-9128-8 · Cited by 24
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Danilova, R. A., Moskvityna, T. A., Obukhova, M. F., Belopolskaya, M. V., & Ашмарин, И. П. (1999) · Neurochemical Research · doi:10.1023/a:1020764504462 · Cited by 8
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Metadata
- Authors
- Behl, T., Kaur, D., Sehgal, A., Singh, S., Sharma, N., Zengin, G., Andronie-Cioara, F. L., Toma, M. M., Bungau, S., & Bumbu, A. G.
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2021-06-18
- Volume
- 26
- Issue
- 12
- Pages
- 3724
- ISSN
- 1420-3049 (ISSN-L)
- OpenAlex
- W3174212201
- Cited by
- 317
- References
- 119
- FWCI
- 25.85
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.