Probiotics in Food Systems: Significance and Emerging Strategies Towards Improved Viability and Delivery of Enhanced Beneficial Value

Terpou, Antonia; Papadaki, Aikaterini; Lappa, Iliada; Kachrimanidou, Vasiliki; Bosnea, Loulouda; Kopsahelis, Nikolaos

doi:10.3390/nu11071591

Cited by 779Probiotics and Fermented FoodsMicroencapsulation and Drying ProcessesProteins in Food Systems

Probiotics in Food Systems: Significance and Emerging Strategies Towards Improved Viability and Delivery of Enhanced Beneficial Value

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Terpou, Antonia, Papadaki, Aikaterini, Lappa, Iliada, Kachrimanidou, Vasiliki, Bosnea, Loulouda, Kopsahelis, Nikolaos·2019·Nutrients

DOI 10.3390/nu11071591PMC PMC6683253

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Abstract

Preserving the efficacy of probiotic bacteria exhibits paramount challenges that need to be addressed during the development of functional food products. Several factors have been claimed to be responsible for reducing the viability of probiotics including matrix acidity, level of oxygen in products, presence of other lactic acid bacteria, and sensitivity to metabolites produced by other competing bacteria. Several approaches are undertaken to improve and sustain microbial cell viability, like strain selection, immobilization technologies, synbiotics development etc. Among them, cell immobilization in various carriers, including composite carrier matrix systems has recently attracted interest targeting to protect probiotics from different types of environmental stress (e.g., pH and heat treatments). Likewise, to successfully deliver the probiotics in the large intestine, cells must survive food processing and storage, and withstand the stress conditions encountered in the upper gastrointestinal tract. Hence, the appropriate selection of probiotics and their effective delivery remains a technological challenge with special focus on sustaining the viability of the probiotic culture in the formulated product. Development of synbiotic combinations exhibits another approach of functional food to stimulate the growth of probiotics. The aim of the current review is to summarize the strategies and the novel techniques adopted to enhance the viability of probiotics.

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Authors: Terpou, A., Papadaki, A., Lappa, I., Kachrimanidou, V., Bosnea, L., & Kopsahelis, N.
Affiliations: Food Biotechnology Group, Department of Chemistry, University of Patras, GR-26500 Patras, Greece
Ionian University (GR)
Hellenic Agricultural Organization DEMETER, Institute of Technology of Agricultural Products, Dairy Department, Katsikas, 45221 Ioannina, Greece
Corresponding author: Bosnea, Loulouda
Kopsahelis, Nikolaos
ORCID: Terpou, Antonia
Papadaki, Aikaterini
Lappa, Iliada
Kachrimanidou, Vasiliki
Bosnea, Loulouda
Kopsahelis, Nikolaos
Venue: Nutrients
Publisher: MDPI AG
Published: 2019-07-13
Volume: 11
Issue: 7
Pages: 1591
ISSN: 2072-6643 (ISSN-L)
DOI: 10.3390/nu11071591
PMC: PMC6683253
OpenAlex: W2960816097
Cited by: 779
References: 269
Citations by year: 2026: 96 · 2025: 121 · 2024: 137 · 2023: 103 · 2022: 136 · 2021: 121 · 2020: 57 · 2019: 6 · 2018: 1 · 2017: 1
FWCI: 7.22
Type: journal article
Language: en
Open access: gold
dx.doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (vor)
Locations: Nutrients (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Life Sciences › Agricultural and Biological Sciences › Food Science › Microencapsulation and Drying Processes
Life Sciences › Agricultural and Biological Sciences › Food Science › Proteins in Food Systems
Keywords: probiotics, probiotic viability, probiotic delivery, functional foods, cell immobilization, synbiotics, lactic acid bacteria, strain selection, gastrointestinal stress
MeSH terms: Bacteria, Food Analysis, Food Handling, Humans, Probiotics, Microbial Viability, Prebiotics

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Probiotics in Food Systems: Significance and Emerging Strategies Towards Improved Viability and Delivery of Enhanced Beneficial Value

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