Vitamin A Metabolism and Adipose Tissue Biology

Obesity and insulin resistance

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Adipocyte differentiation from the inside out

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Transcriptional regulation of adipogenesis.Preprint

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Adipocytes as regulators of energy balance and glucose homeostasis

Rosen, E. D., & Spiegelman, B. M. (2006) · Nature · doi:10.1038/nature05483 · Cited by 2,170 · cited 1× · see citing works

Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes

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Retinol-Binding Protein 4 and Insulin Resistance in Lean, Obese, and Diabetic Subjects

Graham, T. E., Yang, Q., Blüher, M., Hammarstedt, A., Ciaraldi, T. P., Henry, R. R., Wason, C. J., Oberbach, A., Jansson, P.-A., Smith, U., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa054862 · Cited by 1,319 · see citing works

Gene expression regulation by retinoic acid

Balmer, J. E., & Blomhoff, R. (2002) · Journal of Lipid Research · doi:10.1194/jlr.r100015-jlr200 · Cited by 1,039 · see citing works

Regulation of Lipolysis in Adipocytes

Duncan, R. E., Ahmadian, M., Jaworski, K., Sarkadi-Nagy, E., & Sul, H. S. (2007) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.27.061406.093734 · Cited by 1,021 · see citing works

Peroxisome proliferator-activated receptor (PPAR) gamma: adipose- predominant expression and induction early in adipocyte differentiation

Chawla, A., Schwarz, E. J., Dimaculangan, D. D., & Lazar, M. A. (1994) · Endocrinology · doi:10.1210/endo.135.2.8033830 · Cited by 874 · see citing works

Hepatic stellate cell lipid droplets: A specialized lipid droplet for retinoid storage

Blaner, W. S., O'Byrne, S. M., Wongsiriroj, N., Kluwe, J., D'Ambrosio, D. M., Jiang, H., Schwabe, R. F., Hillman, E. M. C., Piantedosi, R., & Libien, J. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2008.11.001 · Cited by 444 · see citing works

Retinoid-binding proteins: mediators of retinoid action

NOY, N. (2000) · Biochemical Journal · doi:10.1042/bj3480481 · Cited by 422 · see citing works

Retinoid-binding proteins: mediators of retinoid action

Noy, N. (2000) · Biochemical Journal · doi:10.1042/0264-6021:3480481 · Cited by 420 · see citing works

Retinaldehyde represses adipogenesis and diet-induced obesity

Ziouzenkova, O., Orasanu, G., Sharlach, M., Akiyama, T. E., Berger, J. P., Viereck, J. C., Hamilton, J. A., Tang, G., Dolnikowski, G. G., Vogel, S., et al. (2007) · Nature Medicine · doi:10.1038/nm1587 · Cited by 380 · see citing works

Retinol-Binding Protein 4 in Human Obesity

Janke, J., Engeli, S., Boschmann, M., Adams, F., Böhnke, J., Luft, F. C., Sharma, A. M., & Jordan, J. (2006) · Diabetes · doi:10.2337/db06-0616 · Cited by 351 · see citing works

All- <i>trans</i> -Retinoic Acid Represses Obesity and Insulin Resistance by Activating both Peroxisome Proliferation-Activated Receptor β/δ and Retinoic Acid Receptor

Berry, D. C., & Noy, N. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01742-08 · Cited by 345 · see citing works

Cellular retinol‐binding protein I is essential for vitamin A homeostasis

Ghyselinck, N. B., Båvik, C., Sapin, V., Mark, M. P., Bonnier, D., Hindelang, C., Dierich, A., Nilsson, C. B., Håkansson, H., Sauvant, P., et al. (1999) · The EMBO Journal · doi:10.1093/emboj/18.18.4903 · Cited by 319 · see citing works

Retinoids and retinoid-binding protein expression in rat adipocytes.

Tsutsumi, C., Okuno, M., Tannous, L., Piantedosi, R., Allan, M., Goodman, D. S., & Blaner, W. S. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)46017-6 · Cited by 317 · see citing works

Fatty acid metabolism in adipose tissue, muscle and liver in health and disease

Frayn, K. N., Arner, P., & Yki‐Järvinen, H. (2006) · Essays in Biochemistry · doi:10.1042/bse0420089 · Cited by 316 · see citing works

Cellular Retinoid-Binding Proteins

Ong, D. E. (1987) · Archives of Dermatology · doi:10.1001/archderm.1987.01660360140026 · Cited by 308 · see citing works

Retinoic Acid Blocks Adipogenesis by Inhibiting C/EBPβ-Mediated Transcription

Schwarz, E. J., Reginato, M. J., Shao, D., Krakow, S. L., & Lazar, M. A. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.3.1552 · Cited by 302 · see citing works

Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT)

O'Byrne, S. M., Wongsiriroj, N., Libien, J., Vogel, S., Goldberg, I. J., Baehr, W., Palczewski, K., & Blaner, W. S. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m507924200 · Cited by 296 · see citing works

Control of Adipose Triglyceride Lipase Action by Serine 517 of Perilipin A Globally Regulates Protein Kinase A-stimulated Lipolysis in Adipocytes

Miyoshi, H., Perfield, J. W., Souza, S. C., Shen, W., Zhang, H., Stancheva, Z. S., Kraemer, F. B., Obin, M. S., & Greenberg, A. S. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m605770200 · Cited by 293 · see citing works

The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters

Yen, C. E., Monetti, M., Burri, B. J., & Farese, R. V. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m500036-jlr200 · Cited by 280 · see citing works

Identification, Expression, and Substrate Specificity of a Mammalian β-Carotene 15,15′-Dioxygenase

Redmond, T. M., Gentleman, S., Duncan, T. E., Yu, S., Wiggert, B. O., Gantt, E., & Cunningham, F. X. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009030200 · Cited by 279 · see citing works

Peroxisome Proliferator Activated Receptor γ, CCAAT/ Enhancer-binding Protein α, and Cell Cycle Status Regulate the Commitment to Adipocyte Differentiation

Shao, D., & Lazar, M. A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.34.21473 · Cited by 272 · see citing works

CMO1 Deficiency Abolishes Vitamin A Production from β-Carotene and Alters Lipid Metabolism in Mice

Hessel, S., Eichinger, A., Isken, A., Amengual, J., Hunzelmann, S., Hoeller, U., Elste, V., Hunziker, W., Goralczyk, R., Oberhauser, V., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m706763200 · Cited by 259 · see citing works

Remodeling of White Adipose Tissue after Retinoic Acid Administration in Mice

Mercader, J., Ribot, J., Murano, I., Felipe, F., Cinti, S., Bonet, M. L., & Palou, A. (2006) · Endocrinology · doi:10.1210/en.2006-0760 · Cited by 244 · see citing works

Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid

Duester, G., Mic, F. A., & Molotkov, A. (2003) · Chemico-Biological Interactions · doi:10.1016/s0009-2797(02)00204-1 · Cited by 243 · see citing works

Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism

Parés, X., Farrés, J., Kedishvili, N., & Duester, G. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8591-3 · Cited by 242 · see citing works

Plasma Delivery of Retinoic Acid to Tissues in the Rat

Kurlandsky, S. B., Gamble, M. V., Ramakrishnan, R., & Blaner, W. S. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.30.17850 · Cited by 242 · see citing works

Elevated Retinol-Binding Protein 4 Levels Are Associated with Metabolic Syndrome in Chinese People

Qi, Q., Yu, Z., Ye, X., Zhao, F., Huang, P., Hu, F. B., Franco, O. H., Wang, J., Li, H., Liu, Y., et al. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1219 · Cited by 209 · see citing works

Retinoid metabolism and nuclear receptor responses: New insights into coordinated regulation of the PPAR–RXR complex

Ziouzenkova, O., & Plutzky, J. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.11.081 · Cited by 202 · see citing works

Cellular metabolism and activation of retinoids: roles of cellular retinoid‐binding proteins 2

Eoss, A. C. (1993) · The FASEB Journal · doi:10.1096/fasebj.7.2.8440409 · Cited by 183 · see citing works

Shortcomings in methodology complicate measurements of serum retinol binding protein (RBP4) in insulin-resistant human subjects

Graham, T. E., Wason, C. J., Blüher, M., & Kahn, B. B. (2007) · Diabetologia · doi:10.1007/s00125-006-0557-0 · Cited by 181 · see citing works

Distinct Stages in Adipogenesis Revealed by Retinoid Inhibition of Differentiation after Induction of PPARγ

Xue, J.-C., Schwarz, E. J., Chawla, A., & Lazar, M. A. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.4.1567 · Cited by 181 · see citing works

Disruption of the lecithin:retinol acyltransferase gene makes mice more susceptible to Vitamin A deficiency

Liu, L., & Gudas, L. J. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m509643200 · Cited by 181 · see citing works

Retinol-binding protein 4 is associated with components of the metabolic syndrome, but not with insulin resistance, in men with type 2 diabetes or coronary artery disease

von Eynatten, M., Lepper, P. M., Liu, D., Lang, K., Baumann, M., Nawroth, P. P., Bierhaus, A., Dugi, K. A., Heemann, U. W., Allolio, B., et al. (2007) · Diabetologia · doi:10.1007/s00125-007-0743-8 · Cited by 171 · see citing works

Changes of Adiposity in Response to Vitamin A Status Correlate with Changes of PPARγ2 Expression

Ribot, J., Felipe, F., Bonet, M. L., & Palou, A. (2001) · Obesity Research · doi:10.1038/oby.2001.65 · Cited by 153 · see citing works

Expression and Characterization of a Murine Enzyme Able to Cleave β-Carotene

Paik, J., During, A., Harrison, E. H., Mendelsohn, C. L., Lai, K., & Blaner, W. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m010086200 · Cited by 150 · see citing works

β,β-Carotene Decreases Peroxisome Proliferator Receptor γ Activity and Reduces Lipid Storage Capacity of Adipocytes in a β,β-Carotene Oxygenase 1-dependent Manner

Lobo, G. P., Amengual, J., Li, H. N. M., Golczak, M., Bonet, M. L., Palczewski, K., & Lintig, J. V. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.132571 · Cited by 149 · see citing works

Serum Retinol-Binding Protein 4 Concentration and Its Ratio to Serum Retinol Are Associated with Obesity and Metabolic Syndrome Components in Children

Herter‐Aeberli, I., Biebinger, R., Lehmann, R., l’Allemand, D., Spinas, G. A., & Zimmermann, M. B. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0468 · Cited by 149 · see citing works

Circulating Retinol-Binding Protein-4, Insulin Sensitivity, Insulin Secretion, and Insulin Disposition Index in Obese and Nonobese Subjects

Broch, M., Vendrell, J. J., Ricart, W., Richart, C., & Fernández‐Real, J. M. (2007) · Diabetes Care · doi:10.2337/dc06-2034 · Cited by 149 · see citing works

Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids.

Gallego, O., Belyaeva, O., Porté, S., Ruiz, F., Stetsenko, A., Shabrova, E., Kostereva, N., Farrés, J., Parés, X., & Kedishvili, N. (2006) · Biochemical Journal · doi:10.1042/bj20051988 · Cited by 130 · see citing works

Characterization of a New Member of the Fatty Acid-binding Protein Family That Binds All-trans-retinol

Vogel, S., Mendelsohn, C. L., Mertz, J. R., Piantedosi, R., Waldburger, C. D., Gottesman, M. E., & Blaner, W. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m005118200 · Cited by 127 · see citing works

The Molecular Basis of Retinoid Absorption

Wongsiriroj, N., Piantedosi, R., Palczewski, K., Goldberg, I. J., Johnston, T. P., Li, E., & Blaner, W. S. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m800777200 · Cited by 126 · see citing works

Modulation of Resistin Expression by Retinoic Acid and Vitamin A Status

Felipe, F., Bonet, M. L., Ribot, J., & Palou, A. (2004) · Diabetes · doi:10.2337/diabetes.53.4.882 · Cited by 123 · see citing works

Evidence That Kidney Function but Not Type 2 Diabetes Determines Retinol-Binding Protein 4 Serum Levels

Henze, A., Frey, S. K., Raila, J., Tepel, M., Scholze, A., Pfeiffer, A. F. H., Weickert, M. O., Spranger, J., & Schweigert�, F. J. (2008) · Diabetes · doi:10.2337/db08-0866 · Cited by 109 · see citing works

Acyl coenzyme A dependent retinol esterification by acyl coenzyme A:diacylglycerol acyltransferase 1

Orland, M. D., Anwar, K., Cromley, D., Chu, C.-H., Chen, L., Billheimer, J. T., Hussain, M. M., & Cheng, D. (2005) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2005.09.003 · Cited by 97 · see citing works

Retinol saturase promotes adipogenesis and is downregulated in obesity

Schupp, M., Lefterova, M. I., Janke, J., Leitner, K., Cristancho, A. G., Mullican, S. E., Qatanani, M., Szwergold, N. R., Steger, D. J., Curtin, J. C., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0812065106 · Cited by 96 · see citing works

Lipoprotein lipase expression level influences tissue clearance of chylomicron retinyl ester

van Bennekum, A. M., Kako, Y., Weinstock, P. H., Harrison, E. H., Deckelbaum, R. J., Goldberg, I. J., & Blaner, W. S. (1999) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32461-5 · Cited by 93 · see citing works

Altered vitamin A homeostasis and increased size and adiposity in the rdhl‐null mouse

Zhang, M., Hu, P., Krois, C. R., Kane, M. A., & Napoli, J. L. (2007) · The FASEB Journal · doi:10.1096/fj.06-7964com · Cited by 91 · see citing works

Biosynthesis, Absorption, Metabolism and Transport of Retinoids

Vogel, S., Gamble, M. V., & Blaner, W. S. (1999) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-58483-1_2 · Cited by 90 · see citing works

Effects of retinoic acid administration and dietary vitamin A supplementation on leptin expression in mice: lack of correlation with changes of adipose tissue mass and food intake

Felipe, F., Mercader, J., Ribot, J., Palou, A., & Bonet, M. L. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2004.11.014 · Cited by 80 · see citing works

Serum Levels of Adipokine Retinol-Binding Protein-4 in Relation to Renal Function

Ziegelmeier, M., Bachmann, A., Seeger, J., Lössner, U., Kratzsch, J., Blüher, M., Stümvoll, M., & Faßhauer, M. (2007) · Diabetes Care · doi:10.2337/dc07-0275 · Cited by 80 · see citing works

Fatty acyl CoA-dependent and -independent retinol esterification by rat liver and lactating mammary gland microsomes

Randolph, R. K., Winkler, K. E., & Ross, A. C. (1991) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(91)90227-a · Cited by 74 · see citing works

Cellular retinol-binding protein type III is a PPARγ target gene and plays a role in lipid metabolism

Zizola, C. F., Schwartz, G. J., & Vogel, S. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90464.2008 · Cited by 60 · see citing works

Effect of retinoic acid on differentiation of cultured pig preadipocytes.

Suryawan, A., & Hu, C. Y. (1997) · Journal of Animal Science · doi:10.2527/1997.751112x · Cited by 59 · see citing works

Cellular Retinol-Binding Protein Type I (CRBP-I) Regulates Adipogenesis

Zizola, C. F., Frey, S. K., Jitngarmkusol, S., Kadereit, B., Yan, N., & Vogel, S. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00014-10 · Cited by 56 · see citing works

Repression of Cellular Retinoic Acid-binding Protein II during Adipocyte Differentiation

Berry, D. C., Soltanian, H. T., & Noy, N. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.110635 · Cited by 55 · see citing works

Cellular Retinol-binding Protein Type III Is Needed for Retinoid Incorporation into Milk*

Piantedosi, R., Ghyselinck, N., Blaner, W., & Vogel, S. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m503906200 · Cited by 53 · see citing works

A Gene Knockout Corroborates the Integral Function of Cellular Retinol-binding Protein in Retinoid Metabolism

Napoli, J. L. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.2000.tb01870.x · Cited by 51 · see citing works

Vitamin A regulates obesity in WNIN/Ob obese rat; independent of stearoyl-CoA desaturase-1

Jeyakumar, S. M., Vajreswari, A., & Giridharan, N. V. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.03.073 · Cited by 48 · see citing works

Contribution of cellular retinol‐binding protein type 1 to retinol metabolism during mouse development

Matt, N., Schmidt, C. K., Dupé, V., Dennefeld, C., Nau, H., Chambon, P., Mark, M. P., & Ghyselinck, N. B. (2005) · Developmental Dynamics · doi:10.1002/dvdy.20313 · Cited by 45 · see citing works

Homeostasis of retinol in lecithin: Retinol acyltransferase gene knockout mice fed a high retinol diet

Liu, L., Tang, X.-H., & Gudas, L. J. (2008) · Biochemical Pharmacology · doi:10.1016/j.bcp.2008.03.012 · Cited by 35 · see citing works

Plasma retinol-binding protein is not a marker of insulin resistance in overweight subjects: A three year longitudinal study

Lewis, J. G., Shand, B. I., Frampton, C. M., Elder, P. A., & Scott, R. S. (2008) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2008.06.002 · Cited by 32 · see citing works

Regulation of adipocyte differentiation by PEGylated all-trans retinoic acid: reduced cytotoxicity and attenuated lipid accumulation

Moon, H. S., Guo, D., Song, H. H., Kim, I., Jin, H. Z., KIM, Y., CHUNG, C., Choi, Y., Lee, H. K., & Cho, C. S. (2006) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2006.06.004 · Cited by 30 · see citing works

CRBP‐III:lacZ expression pattern reveals a novel heterogeneity of vascular endothelial cells

Caprioli, A., Zhu, H., & Sato, T. N. (2004) · genesis · doi:10.1002/gene.20075 · Cited by 27 · see citing works

An ELISA for plasma retinol-binding protein using monoclonal and polyclonal antibodies: Plasma variation in normal and insulin resistant subjects

Lewis, J. G., Shand, B. I., Frampton, C. M., & Elder, P. A. (2007) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2007.03.021 · Cited by 16 · see citing works

Radiation inactivation analysis of acyl-CoA:retinol acyltransferase and lecithin:retinol acyltransferase in rat liver

Ross, A., & Kempner, E. S. (1993) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37707-5 · Cited by 13 · see citing works

Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch

Cohen, P., Levy, J. D., Zhang, Y., Frontini, A., Kolodin, D., Svensson, K. J., Lo, J. C., Zeng, X., Ye, L., Khandekar, M. J., et al. (2014) · Cell · doi:10.1016/j.cell.2013.12.021 · Cited by 878 · see citing works

Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity

Bonet, M. L., Canas, J. A., Ribot, J., & Palou, A. (2015) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2015.02.022 · Cited by 223 · see citing works

Mechanistic aspects of carotenoid health benefits – where are we now?

Bohn, T., Bonet, M. L., Borel, P., Keijer, J., Landrier, J., Milisav, I., Ribot, J., Riso, P., Winklhofer-Roob, B., Sharoni, Y., et al. (2021) · Nutrition Research Reviews · doi:10.1017/s0954422421000147 · Cited by 151 · see citing works

Nutrient deficiencies after gastric bypass surgery.

Saltzman, E., & Karl, J. (2013) · Annual review of nutrition · doi:10.1146/annurev-nutr-071812-161225 · Cited by 151 · see citing works

Detecting tissue-specific early warning signals for complex diseases based on dynamical network biomarkers: study of type 2 diabetes by cross-tissue analysis

Li, M., Zeng, T., Liu, R., & Chen, L. (2013) · Briefings in Bioinformatics · doi:10.1093/bib/bbt027 · Cited by 142 · see citing works

Pseudotumor Cerebri Pathophysiology

McGeeney, B. E., & Friedman, D. I. (2014) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12291 · Cited by 122 · see citing works

The Role of Vitamin A in Retinal Diseases

Sajovic, J., Meglič, A., Glavač, D., Markelj, Š., Hawlina, M., & Fakin, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031014 · Cited by 109 · see citing works

Serum amyloid A delivers retinol to intestinal myeloid cells to promote adaptive immunity

Bang, Y., Hu, Z., Li, Y., Gattu, S., Ruhn, K. A., Raj, P., Herz, J., & Hooper, L. V. (2021) · Science · doi:10.1126/science.abf9232 · Cited by 93 · see citing works

Can metabolically healthy obesity be explained by diet, genetics, and inflammation?

Navarro, E., Funtikova, A. N., Fitó, M., & Schröder, H. (2014) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201400521 · Cited by 91 · see citing works

Carotenoids in Adipose Tissue Biology and Obesity

Bonet, M. L., Canas, J. A., Ribot, J., & Palou, A. (2016) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-319-39126-7_15 · Cited by 78 · see citing works

Obesity and Insulin Resistance Are Inversely Associated with Serum and Adipose Tissue Carotenoid Concentrations in Adults

Harari, A., Coster, A. C. F., Jenkins, A. B., Xu, A., Greenfield, J. R., Harats, D., Shaish, A., & Samocha‐Bonet, D. (2019) · Journal of Nutrition · doi:10.1093/jn/nxz184 · Cited by 75 · see citing works

Prenatally Acquired Vitamin A Deficiency Alters Innate Immune Responses to Human Rotavirus in a Gnotobiotic Pig Model

Vlasova, A. N., Chattha, K. S., Kandasamy, S., Siegismund, C. S., & Saif, L. J. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1203575 · Cited by 64 · see citing works

Prioritizing Environmental Chemicals for Obesity and Diabetes Outcomes Research: A Screening Approach Using ToxCast™ High-Throughput Data

Auerbach, S. S., Filer, D. L., Reif, D. M., Walker, V. R., Holloway, A. C., Schlezinger, J. J., Srinivasan, S., Svoboda, D. L., Judson, R., Bucher, J. R., et al. (2016) · Environmental Health Perspectives · doi:10.1289/ehp.1510456 · Cited by 60 · see citing works

Role of vitamin A in type 2 diabetes mellitus biology: Effects of intervention therapy in a deficient state

Iqbal, S., & Naseem, I. (2014) · Nutrition · doi:10.1016/j.nut.2014.12.014 · Cited by 61 · see citing works

Reduced adiponectin expression after high‐fat diet is associated with selective up‐regulation of ALDH1A1 and further retinoic acid receptor signaling in adipose tissue

Landrier, J., Kasiri, E., Karkeni, E., Mihály, J., Béke, G., Weiss, K., Lucas, R., Aydemir, G., Salles, J., Walrand, S., et al. (2016) · The FASEB Journal · doi:10.1096/fj.201600263rr · Cited by 61 · see citing works

Vitamin A derivatives as treatment options for retinal degenerative diseases

Perusek, L., & Maeda, T. (2013) · Nutrients · doi:10.3390/nu5072646 · Cited by 60 · see citing works

The Concentration of β-Carotene in Human Adipocytes, but Not the Whole-Body Adipocyte Stores, Is Reduced in Obesity

Östh, M., Öst, A., Kjølhede, P., & Strålfors, P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0085610 · Cited by 54 · see citing works

Inverse association between dietary vitamin A intake and new-onset hypertension

Zhang, Y., Liu, M., Zhou, C., Zhang, Z., He, P., Li, Q., Liu, C., & Qin, X. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.04.004 · Cited by 49 · see citing works

Retinoic Acid Mediates Visceral-Specific Adipogenic Defects of Human Adipose-Derived Stem Cells

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Insulin Regulates Retinol Dehydrogenase Expression and All-trans-retinoic Acid Biosynthesis through FoxO1

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Long-term Diet and Biomarker Changes after a Short-term Intervention among Hispanic Breast Cancer Survivors: The¡Cocinar Para Su Salud!Randomized Controlled Trial

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Optical Spectral Surveillance of Breast Tissue Landscapes for Detection of Residual Disease in Breast Tumor Margins

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Vitamin A as a key regulator of obesity & its associated disorders: Evidences from an obese rat model

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Rationale and design of the school-based SI! Program to face obesity and promote health among Spanish adolescents: A cluster-randomized controlled trial

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Maternal smoking and the retinoid pathway in the developing lung

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Vitamin A regulates intramuscular adipose tissue and muscle development: promoting high-quality beef production

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Influence of dietary patterns on the metabolically healthy obesity phenotype: A systematic review

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Carotenoids as Functional Bioactive Compounds

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Vitamin a supplementation, serum lipids, liver enzymes and C-reactive protein concentrations in obese women of reproductive age

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The conversion of β-carotene to vitamin A in adipocytes drives the anti-obesogenic effects of β-carotene in mice

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Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis

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Molecular Mechanisms of Retinoid Receptors in Diabetes-Induced Cardiac Remodeling

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Dietary vitamin A impacts DNA methylation patterns of adipogenesis-related genes in suckling rats

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Dynamics of Serum Retinol and Alpha-Tocopherol Levels According to Non-Alcoholic Fatty Liver Disease Status

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β-Carotene stimulates browning of 3T3-L1 white adipocytes by enhancing thermogenesis via the β3-AR/p38 MAPK/SIRT signaling pathway

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RNA-sequencing and pathway analysis reveal alteration of hepatic steroid biosynthesis and retinol metabolism by tributyltin exposure in male rare minnow ( Gobiocypris rarus )

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Plasma retinol and the risk of first stroke in hypertensive adults: a nested case-control study

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Relationship between the Nutritional Status of Vitamin A per Trimester of Pregnancy with Maternal Anthropometry and Anemia after Roux-en-Y Gastric Bypass

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All-trans retinoic acid induces mitochondria-mediated apoptosis of human adipose-derived stem cells and affects the balance of the adipogenic differentiation

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Supplementation with 9-cis β-carotene-rich alga Dunaliella improves hyperglycemia and adipose tissue inflammation in diabetic mice

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Proteomic analysis reveals changes in energy metabolism of skeletal muscle in beef cattle supplemented with vitamin A

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Retinol intake is associated with the risk of chronic kidney disease in individuals with type 2 diabetes mellitus: results from NHANES

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Involvement of Dietary Fatty Acids in Multiple Biological and Psychological Functions, in Morbidly Obese Subjects

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Retinol Binding Protein 7 Promotes Adipogenesis in vitro and Regulates Expression of Genes Involved in Retinol Metabolism

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Vitamin A homeostasis and cardiometabolic disease in humans: lost in translation?

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Effect of Saccharomyces cerevisiae fermentation product on oxidative status, inflammation, and immune response in transition dairy cattle

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Body condition alters glutathione and nuclear factor erythroid 2-like 2 (NFE2L2)–related antioxidant network abundance in subcutaneous adipose tissue of periparturient Holstein cows

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Long term vitamin A restriction improves meat quality parameters and modifies gene expression in Iberian pigs1

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Aldehyde dehydrogenase 1 a1 regulates energy metabolism in adipocytes from different species

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Long-term in vivo survival of 3D-bioprinted human lipoaspirate-derived adipose tissue: proteomic signature and cellular content

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Dietary vitamin A modifies the gut microbiota and intestinal tissue transcriptome, impacting intestinal permeability and the release of inflammatory factors, thereby influencing Aβ pathology

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Vitamin A Supplementation during Suckling and Postweaning Periods Attenuates the Adverse Metabolic Effects of Maternal High-Fat Diet Consumption in Sprague-Dawley Rats

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Effects of dietary vitamin A supplementation or restriction and its timing on retinol and α-tocopherol accumulation and gene expression in heavy pigs

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Supplementation of Micro- and Macronutrients—A Role of Nutritional Status in Non-Alcoholic Fatty Liver Disease

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Serum levels of vitamin A, visual function and ocular surface after bariatric surgery

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Vitamin A

Combs, G. F., & McClung, J. P. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-802965-7.00006-x · Cited by 13 · see citing works

Association of nonalcoholic fatty liver disease and liver fibrosis detected by transient elastography with serum retinol in American adults

Niu, X., Liu, J., & Liu, K. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1094161 · Cited by 12 · see citing works

Proteomic Analysis of Endometrial Cancer Tissues from Patients with Type 2 Diabetes Mellitus

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Inhibition of fat cell differentiation in 3T3-L1 pre-adipocytes by all-trans retinoic acid: Integrative analysis of transcriptomic and phenotypic data

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Metabolomic Insights into the Mechanisms of Ganoderic Acid: Protection against α-Amanitin-Induced Liver Injury

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Role of PPARγ in the nutritional and pharmacological actions of carotenoids

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Enzymatic intracrine regulation of white adipose tissue

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The relationships of high-fat diet and metabolism of lipophilic vitamins

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High-dimensional profiling demonstrates complexity, tissue imprinting, and lineage-specific precursors within the mononuclear phagocyte compartment of the human intestinePreprint

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Possible resting metabolic rate modification by the circulating RBP4 in obese subjects

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Retinoic acid is abundantly detected in different depots of adipose tissue by SERS

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Dietary antioxidant intake is inversely associated with 2,3-dinor oxylipin metabolites, the major excreted oxylipins in overweight and obese subjects

Lara-Guzmán, O. J., Rivera, D. A., Corrales-Agudelo, V., Salazar-Jaramillo, L., Gil‐Izquierdo, Á., Medina, S., Oger, C., Durand, T., Galano, J., Escobar, J. S., et al. (2022) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.07.023 · Cited by 8 · see citing works

Integrated assessment of biomarker responses and comparative toxicity pathway in snails Bellamya aeruginosa exposed to tributyltin and triphenyltin in sediments

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Differential expression and functional analysis of circRNA in the ovaries of Yili geese at different egg-laying stages

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Obesity and Micronutrient Deficiencies

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Subcutaneous white adipose tissue–derived extracellular vesicles maintain intestinal homeostasis via IgA biosynthesis in aging mice

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Factors and Molecular Mechanisms of Vitamin A and Childhood Obesity Relationship: A Review

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Visceral fat obesity predicts ossification of the posterior longitudinal ligament: annual health examination data-based evidence

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Retinoic acid promotes tissue vitamin A status and modulates adipose tissue metabolism of neonatal rats exposed to maternal high-fat diet-induced obesity

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Vitamin A Status and Deposition in Neonatal and Weanling Rats Reared by Mothers Consuming Normal and High-Fat Diets with Adequate or Supplemented Vitamin A

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Adipose‐Specific Expression, Developmental and Nutritional Regulation of the Gene‐Encoding Retinol‐Binding Protein 7 in Pigs

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All-Trans Retinoic Acid Inhibits Bone Marrow Mesenchymal Stem Cell Commitment to Adipocytes via Upregulating FRA1 Signaling

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Correlation between the Serum Concentration of Vitamin A and Disease Severity in Patients Carrying p.G90D in RHO, the Most Frequent Gene Associated with Dominant Retinitis Pigmentosa: Implications for Therapy with Vitamin A

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Vitamin A Derivatives and Adipose Tissue Differentiation: Molecular Pathways Driving Browning and Anti-Obesity Effects

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Overweight effects on metabolic rate, time perception, diseases, aging, and lifespan: A systematic review with meta-regression analysis

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An in-silico study to investigate the role of β-cryptoxanthin on obesity

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Are plasma 25-hydroxyvitamin D and retinol levels and one-carbon metabolism related to metabolic syndrome in patients with a severe mental disorder?

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Dietary vitamins A and K are inversely associated with visceral adiposity in US adults: NHANES 2011–2018

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Effects of Nutrients, Mainly from Mediterranean Dietary Foods, on Mesenchymal Stem Derived Cells: Growth or Differentiation

Ammendola, S., Cocchiola, R., Lopreiato, M., & Abusco, A. D. (2018) · International Journal of Clinical Nutrition & Dietetics · doi:10.15344/2456-8171/2018/131 · Cited by 3 · see citing works

Time-dependent changes in retinoids content in liver and adipose tissue after feeding of a vitamin A-deficient diet to mice

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Biological Response of Epithelial Cells line (CMT-93) Induced by β-Carotene

Roosita, K., Martopuro, R. S., Djuwita, I., Damanik, M. R., Kusharto, C. M., & Tani, F. (2013) · Pakistan Journal of Nutrition · doi:10.3923/pjn.2013.615.619 · Cited by 3 · see citing works

Effects of Retinoid Treatment on Cochlear Development, Connexin Expression and Hearing Thresholds in Mice

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Transcriptomics of a cytoglobin knockout mouse: Insights from hepatic stellate cells and brain

Porto, E., Backer, J. D., Thủy, L. T. T., Kawada, N., & Hankeln, T. (2023) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2023.112405 · Cited by 2 · see citing works

Vitamin A insufficiency in obese Egyptian children with dyslipidemia

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Environmental and prey‐based factors underpinning variability in prairie dogs eaten by black‐footed ferrets

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Vitamins | Vitamin A (Retinoids)

Napoli, J. (2021) · Encyclopedia of Biological Chemistry III · doi:10.1016/b978-0-12-809633-8.21374-5 · Cited by 1 · see citing works

Enhancement of Carotenoid Profile and Beta‐Carotene Bioavailability in African Locust Bean Pulp–Supplemented Instant Kunu Beverage

Olatoye, K. K., Irondi, E. A., Awoyale, W., Adeyemo, O. I., & Akinpade, M. R. (2026) · Journal of Food Processing and Preservation · doi:10.1155/jfpp/1712864 · Cited by 1 · see citing works

Large-scale proteomic analysis of Japanese Black cattle:Part II. Assessment of gender and genetic background effects

池上春香, KOBAYASHI, N., 珠子, 松., 武本, 淳., 吉廣, 卓., INOUE, E., 加藤, 里., 博己, 加., 田口, 善., 朋子, 天., et al. (2012) · Nihon Chikusan Gakkaiho · doi:10.2508/chikusan.83.281 · Cited by 1 · see citing works

Medication-Induced Hypercalcemia

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Vitamin A

Molavi, F., Sarabi‐Aghdam, V., Razi, S. M., & Rashidinejad, A. (2022) · Springer eBooks · doi:10.1007/978-3-030-81404-5_22-1 · Cited by 1 · see citing works

Vitamin a concentrations in Iraqi patients attending Ibn-Al Haitham Eye Hospital

Ahmed, M. H. (2023) · AIP conference proceedings · doi:10.1063/5.0151098 · Cited by 1 · see citing works

Understanding health disparities affecting people of West Central African descent in the United States: An evolutionary perspective

Mawson, A. R. (2023) · Evolutionary Applications · doi:10.1111/eva.13549 · Cited by 1 · see citing works

Vitamin A

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Cold-mediated regulation of systemic retinol transport controls adipose tissue browningPreprint

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