The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
DHA Effects in Brain Development and Function
Open accessAbstract
Docosahexaenoic acid (DHA) is a structural constituent of membranes specifically in the central nervous system. Its accumulation in the fetal brain takes place mainly during the last trimester of pregnancy and continues at very high rates up to the end of the second year of life. Since the endogenous formation of DHA seems to be relatively low, DHA intake may contribute to optimal conditions for brain development. We performed a narrative review on research on the associations between DHA levels and brain development and function throughout the lifespan. Data from cell and animal studies justify the indication of DHA in relation to brain function for neuronal cell growth and differentiation as well as in relation to neuronal signaling. Most data from human studies concern the contribution of DHA to optimal visual acuity development. Accumulating data indicate that DHA may have effects on the brain in infancy, and recent studies indicate that the effect of DHA may depend on gender and genotype of genes involved in the endogenous synthesis of DHA. While DHA levels may affect early development, potential effects are also increasingly recognized during childhood and adult life, suggesting a role of DHA in cognitive decline and in relation to major psychiatric disorders.
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Cross-national epidemiology of major depression and bipolar disorder
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The clinical relevance of omega-3 fatty acids in the management of hypertriglyceridemia
Backes, J., Anzalone, D., Hilleman, D., & Catini, J. (2016) · Lipids in Health and Disease · doi:10.1186/s12944-016-0286-4 · Cited by 195
Microalgae as Sources of Omega-3 Polyunsaturated Fatty Acids: Biotechnological Aspects
Barta, D. G., Coman, V., & Vodnar, D. C. (2021) · Algal Research · doi:10.1016/j.algal.2021.102410 · Cited by 178
Clemens, V., von Hirschhausen, E., & Fegert, J. M. (2022) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-020-01615-3 · Cited by 147
Díaz, M., Mesa-Herrera, F., & Marín, R. (2021) · Antioxidants · doi:10.3390/antiox10060907 · Cited by 84
Metadata
- Authors
- Lauritzen, L., Brambilla, P., Mazzocchi, A., Harsløf, L., Ciappolino, V., & Agostoni, C.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2016-01-04
- Volume
- 8
- Issue
- 1
- Pages
- 6
- ISSN
- 2072-6643 (ISSN-L)
- OpenAlex
- W2206567631
- Cited by
- 558
- References
- 6
- FWCI
- 38.98
- Type
- journal article
- Language
- en
- Open access
- gold
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