The Metabolic and Ecological Interactions of Oxalate-Degrading Bacteria in the Mammalian Gut
Open accessAbstract
Oxalate-degrading bacteria comprise a functional group of microorganisms, commonly found in the gastrointestinal tract of mammals. Oxalate is a plant secondary compound (PSC) widely produced by all major taxa of plants and as a terminal metabolite by the mammalian liver. As a toxin, oxalate can have a significant impact on the health of mammals, including humans. Mammals do not have the enzymes required to metabolize oxalate and rely on their gut microbiota for this function. Thus, significant metabolic interactions between the mammalian host and a complex gut microbiota maintain the balance of oxalate in the body. Over a dozen species of gut bacteria are now known to degrade oxalate. This review focuses on the host-microbe and microbe-microbe interactions that regulate the degradation of oxalate by the gut microbiota. We discuss the pathways of oxalate throughout the body and the mammalian gut as a series of differentiated ecosystems that facilitate oxalate degradation. We also explore the mechanisms and functions of microbial oxalate degradation along with the implications for the ecological and evolutionary interactions within the microbiota and for mammalian hosts. Throughout, we consider questions that remain, as well as recent technological advances that can be employed to answer them.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Recent evidence suggests that blood oxalate levels are influenced by gut microbiota, with over a dozen oxalate-degrading gut bacterial species identified.
“Recent evidence suggests that blood levels are also influenced by gut microbiota, with over a dozen oxalate-degrading gut bacterial species identified (28).”
From Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt (2015) · cites this paper as [28]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
A human gut microbial gene catalogue established by metagenomic sequencing
MetaHIT Consortium, Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., et al. (2010) · Nature · doi:10.1038/nature08821 · Cited by 11,624 · see citing works
The gut microbiota shapes intestinal immune responses during health and disease
Round, J. L., & Mazmanian, S. K. (2009) · Nature Reviews Immunology · doi:10.1038/nri2515 · Cited by 5,029 · see citing works
Prokaryotes: The unseen majority
Whitman, W. B., Coleman, D. C., & Wiebe, W. J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.12.6578 · Cited by 4,871 · cited 1× · see citing works
“Hindgut fermenting mammals such as horses, guinea pigs, wombats, and rabbits, have an enlarged hindgut, which is the primary site for the microbiota and house communities distinct from foregut fermenters [27,82,83].”
BackgroundHost-gut microbiota metabolic interactions
Nicholson, J. K., Holmes, E., Kinross, J., Burcelin, R., Gibson, G., Jia, W., & Pettersson, S. (2012) · Science · doi:10.1126/science.1223813 · Cited by 4,760 · see citing works
Interactions Between the Microbiota and the Immune System
Hooper, L. V., Littman, D. R., & Macpherson, A. J. (2012) · Science · doi:10.1126/science.1223490 · Cited by 4,173 · see citing works
Evolution of mammals and their gut microbes
Ley, R. E., Hamady, M., Lozupone, C., Turnbaugh, P. J., Ramey, R. R., Bircher, J. S., Schlegel, M. L., Tucker, T. A., Schrenzel, M. D., Knight, R., et al. (2008) · Science · doi:10.1126/science.1155725 · Cited by 3,747 · see citing works
Ecological and Evolutionary Forces Shaping Microbial Diversity in the Human Intestine
Ley, R. E., Peterson, D. A., & Gordon, J. I. (2006) · Cell · doi:10.1016/j.cell.2006.02.017 · Cited by 3,358 · see citing works
The gut flora as a forgotten organ
O'Hara, A. M., & Shanahan, F. (2006) · The EMBO Reports · doi:10.1038/sj.embor.7400731 · Cited by 2,791 · see citing works
Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5
Vijay-Kumar, M., Aitken, J. D., Carvalho, F. A., Cullender, T. C., Mwangi, S., Srinivasan, S., Sitaraman, S. V., Knight, R., Ley, R. E., & Gewirtz, A. T. (2010) · Science · doi:10.1126/science.1179721 · Cited by 2,068 · see citing works
Diet Drives Convergence in Gut Microbiome Functions Across Mammalian Phylogeny and Within Humans
Muegge, B. D., Kuczynski, J., Knights, D., Clemente, J. C., González, A., Fontana, L., Henrissat, B., Knight, R., & Gordon, J. I. (2011) · Science · doi:10.1126/science.1198719 · Cited by 1,988 · see citing works
An ecological and evolutionary perspective on human–microbe mutualism and disease
Dethlefsen, L., McFall-Ngai, M., & Relman, D. A. (2007) · Nature · doi:10.1038/nature06245 · Cited by 1,660 · see citing works
Worlds within worlds: evolution of the vertebrate gut microbiota
Ley, R. E., Lozupone, C., Hamady, M., Knight, R. D., & Gordon, J. I. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1978 · Cited by 1,652 · see citing works
H OW H OST -M ICROBIAL I NTERACTIONS S HAPE THE N UTRIENT E NVIRONMENT OF THE M AMMALIAN I NTESTINE
Hooper, L. V., Midtvedt, T., & Gordon, J. I. (2002) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.22.011602.092259 · Cited by 1,623 · see citing works
Strategies in Herbivory by Mammals: The Role of Plant Secondary Compounds
Freeland, W. J., & Janzen, D. H. (1974) · The American Naturalist · doi:10.1086/282907 · Cited by 1,358 · see citing works
CALCIUM OXALATE IN PLANTS: Formation and Function
Franceschi, V. R., & Nakata, P. A. (2005) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.56.032604.144106 · Cited by 1,264 · see citing works
Gough, E., Shaikh, H., & Manges, A. R. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir632 · Cited by 1,003 · see citing works
Rawls, J. F., Mahowald, M. A., Ley, R. E., & Gordon, J. I. (2006) · Cell · doi:10.1016/j.cell.2006.08.043 · Cited by 962 · see citing works
Ecology drives a global network of gene exchange connecting the human microbiome
Smillie, C. S., Smith, M. B., Friedman, J., Cordero, O. X., David, L. A., & Alm, E. J. (2011) · Nature · doi:10.1038/nature10571 · Cited by 953 · see citing works
Gut microorganisms, mammalian metabolism and personalized health care
Nicholson, J. K., Holmes, E., & Wilson, I. D. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1152 · Cited by 945 · see citing works
Coe, F. L. (2005) · Journal of Clinical Investigation · doi:10.1172/jci26662 · Cited by 786 · see citing works
Interactions Between Gut Microbiota and Host Metabolism Predisposing to Obesity and Diabetes
Musso, G., Gambino, R., & Cassader, M. (2011) · Annual Review of Medicine · doi:10.1146/annurev-med-012510-175505 · Cited by 598 · see citing works
Microbiota restoration: natural and supplemented recovery of human microbial communities
Reid, G., Younes, J. A., van der Mei, H. C., Gloor, G. B., Knight, R. D., & Busscher, H. J. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2473 · Cited by 585 · see citing works
Oxalate content of foods and its effect on humans
Bsc, S. N., & Bsc, G. S. (1999) · Asia Pacific Journal of Clinical Nutrition · doi:10.1046/j.1440-6047.1999.00038.x · Cited by 531 · see citing works
Contribution of dietary oxalate to urinary oxalate excretion
Holmes, R. P., Goodman, H. O., & Assimos, D. G. (2001) · Kidney International · doi:10.1046/j.1523-1755.2001.00488.x · Cited by 502 · see citing works
Allison, M. J., Dawson, K. A., Mayberry, W. R., & Foss, J. G. (1985) · Archives of Microbiology · doi:10.1007/bf00446731 · Cited by 437 · see citing works
Martin, F. J., Wang, Y., Sprenger, N., Yap, I. K. S., Lundstedt, T., Lek, P., Rezzi, S., Ramadan, Z., van Bladeren, P., Fay, L. B., et al. (2008) · Molecular Systems Biology · doi:10.1038/msb4100190 · Cited by 421 · see citing works
Karasov, W. H., & del Rio, C. M. (2007) · Princeton University Press eBooks · doi:10.1515/9780691213316 · Cited by 383 · see citing works
Oxalic acid in biology and medicine
Hodgkinson, A. (1977) · Academic Press eBooks · Cited by 348 · see citing works
Mechanisms of Disease: the hygiene hypothesis revisited
Guarner, F., Bourdet‐Sicard, R., Brandtzæg, P., Gill, H. S., McGuirk, P., van Eden, W., Versalovic, J. A., Weinstock, J. V., & Rook, G. A. W. (2006) · Nature Clinical Practice Gastroenterology & Hepatology · doi:10.1038/ncpgasthep0471 · Cited by 315 · see citing works
Oxalobacter formigenes May Reduce the Risk of Calcium Oxalate Kidney Stones
Kaufman, D. W., Kelly, J. P., Curhan, G. C., Anderson, T. E., Dretler, S. P., Preminger, G. M., & Cave, D. R. (2008) · Journal of the American Society of Nephrology · doi:10.1681/asn.2007101058 · Cited by 299 · see citing works
Dearing, M. D., Foley, W. J., & McLean, S. (2005) · Annual Review of Ecology Evolution and Systematics · doi:10.1146/annurev.ecolsys.36.102003.152617 · Cited by 294 · see citing works
Bacteriotherapy Using Fecal Flora: Toying With Human Motions
Borody, T. J., Warren, E. F., Leis, S. M., Surace, R., Ashman, O., & Siarakas, S. (2004) · Journal of Clinical Gastroenterology · doi:10.1097/01.mcg.0000128988.13808.dc · Cited by 283 · see citing works
Estimation of the oxalate content of foods and daily oxalate intake
Holmes, R. P., & Kennedy, M. (2000) · Kidney International · doi:10.1046/j.1523-1755.2000.00010.x · Cited by 264 · see citing works
Oxalobacter sp. reduces urinary oxalate excretion by promoting enteric oxalate secretion
Hatch, M., Cornelius, J., Allison, M. J., Sidhu, H., Peck, A. B., & Freel, R. W. (2006) · Kidney International · doi:10.1038/sj.ki.5000162 · Cited by 244 · see citing works
Reduction of oxaluria after an oral course of lactic acid bacteria at high concentration
Campieri, C., Campieri, M., Bertuzzi, V., Swennen, E., Matteuzzi, D., Stefoni, S., Pirovano, F., Centi, C., Ulisse, S., Famularo, G., et al. (2001) · Kidney International · doi:10.1046/j.1523-1755.2001.0600031097.x · Cited by 239 · see citing works
Absence of Oxalobacter formigenes in cystic fibrosis patients: a risk factor for hyperoxaluria
Sidhu, H., Hoppe, B., Hesse, A., Tenbrock, K., Brömme, S., Rietschel, E., & Peck, A. B. (1998) · The Lancet · doi:10.1016/s0140-6736(98)03038-4 · Cited by 233 · see citing works
Jones, R. J., & Megarrity, R. (1986) · Australian Veterinary Journal · doi:10.1111/j.1751-0813.1986.tb02990.x · Cited by 230 · see citing works
Oxalate Degradation by Gastrointestinal Bacteria from Humans
Allison, M. J., Cook, H. M., MILNE, D. B., Gallagher, S. K., & Clayman, R. V. (1986) · Journal of Nutrition · doi:10.1093/jn/116.3.455 · Cited by 225 · see citing works
Shimada, T., Saitoh, T., Sasaki, E., Nishitani, Y., & Osawa, R. (2006) · Journal of Chemical Ecology · doi:10.1007/s10886-006-9078-z · Cited by 218 · see citing works
Oxalobacter formigenes: a potential tool for the treatment of primary hyperoxaluria type 1
Höppe, B., Beck, B. B., Gatter, N., von Unruh, G., Tischer, A., Hesse, A., Laube, N., Kaul, P., & Sidhu, H. (2006) · Kidney International · doi:10.1038/sj.ki.5001707 · Cited by 214 · see citing works
Oxalobacter formigenes and Its Potential Role in Human Health
Duncan, S. H., Richardson, A. J., Kaul, P., Holmes, R. P., Allison, M. J., & Stewart, C. S. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.8.3841-3847.2002 · Cited by 188 · see citing works
Sidhu, H., Schmidt, M. E., Cornelius, J. G., Thamilselvan, S., Khan, S. R., Hesse, A., & Peck, A. B. (1999) · PubMed · Cited by 187 · see citing works
Inter-species transplantation of gut microbiota from human to pigs
Pang, X., Hua, X., Yang, Q., Ding, D., Che, C., Cui, L., Jia, W. P., Bucheli, P., & Zhao, L. (2007) · The ISME Journal · doi:10.1038/ismej.2007.23 · Cited by 179 · see citing works
Determinants of 24-hour Urinary Oxalate Excretion
Taylor, E. N., & Curhan, G. C. (2008) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.01410308 · Cited by 173 · see citing works
Use of a probioitic to decrease enteric hyperoxaluria
Lieske, J. C., Goldfarb, D. S., Simone, C. D., & Regnier, C. (2005) · Kidney International · doi:10.1111/j.1523-1755.2005.00520.x · Cited by 171 · see citing works
Hook, S. E., Steele, M. A., Northwood, K. S., Dijkstra, J., France, J., Wright, A. G., & McBride, B. W. (2011) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2011.01154.x · Cited by 171 · see citing works
Hydroxyproline ingestion and urinary oxalate and glycolate excretion
Knight, J. L., Jiang, J., Assimos, D. G., & Holmes, R. P. (2006) · Kidney International · doi:10.1038/sj.ki.5001906 · Cited by 160 · see citing works
Lieske, J. C., Tremaine, W. J., Simone, C. D., O’Connor, H. M., Li, X., Bergstralh, E. J., & Goldfarb, D. S. (2010) · Kidney International · doi:10.1038/ki.2010.310 · Cited by 159 · see citing works
Dietary risk factors for hyperoxaluria in calcium oxalate stone formers
Siener, R., Ebert, D., Nicolay, C., & Hesse, A. (2003) · Kidney International · doi:10.1046/j.1523-1755.2003.00807.x · Cited by 157 · see citing works
Food Oxalate: Factors Affecting Measurement, Biological Variation, and Bioavailability
Massey, L. K. (2007) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2007.04.007 · Cited by 157 · see citing works
Sidhu, H., Allison, M. J., Chow, J., CLARK, A., & Peck, A. B. (2001) · The Journal of Urology · doi:10.1016/s0022-5347(05)65817-x · Cited by 152 · see citing works
Hatch, M., Gjymishka, A., SALIDO, E. C., Allison, M. J., & Freel, R. W. (2010) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00434.2010 · Cited by 147 · see citing works
Hess, B. J. M. (1998) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/13.9.2241 · Cited by 132 · see citing works
Gómez‐Hurtado, I., Santacruz, A., Peiró, G., Zapater, P., Gutiérrez, A., Pérez‐Mateo, M., Sanz, Y., & Francés, R. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023037 · Cited by 128 · see citing works
Turroni, S., Vitali, B., Bendazzoli, C., Candela, M., Gotti, R., Federici, F., Pirovano, F., & Brigidi, P. (2007) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2007.03388.x · Cited by 122 · see citing works
Degradation of tannic acid by cell-free extracts of Lactobacillus plantarum
Rodrı́guez, H., Rivas, B. D. L., Gómez‐Cordovés, C., & Múñoz, R. (2007) · Food Chemistry · doi:10.1016/j.foodchem.2007.08.063 · Cited by 118 · see citing works
Purification and characterization of oxalyl-coenzyme A decarboxylase from Oxalobacter formigenes
Baetz, A. L., & Allison, M. J. (1989) · Journal of Bacteriology · doi:10.1128/jb.171.5.2605-2608.1989 · Cited by 114 · see citing works
Exploitation of secondary metabolites by animals: A response to homeostatic challenges
Forbey, J. S., Harvey, A. L., Huffman, M. A., Provenza, F. D., Sullivan, R., & Taşdemir, D. (2009) · Integrative and Comparative Biology · doi:10.1093/icb/icp046 · Cited by 112 · see citing works
Kageyama, A., Benno, Y., & Nakase, T. (1999) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/00207713-49-4-1725 · Cited by 107 · see citing works
Changes in Ruminal Oxalate Degradation Rates Associated with Adaptation to Oxalate Ingestion
Allison, M. J., Littledike, E. T., & James, L. F. (1977) · Journal of Animal Science · doi:10.2527/jas1977.4551173x · Cited by 104 · see citing works
Ruan, Z.-S., Anantharam, V., Crawford, I. T., Ambudkar, S. V., Rhee, S. Y., Allison, M. J., & Maloney, P. C. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50050-3 · Cited by 99 · see citing works
Nutritional toxicology of mammals: regulated intake of plant secondary compounds
Torregrossa, A., & Dearing, M. D. (2009) · Functional Ecology · doi:10.1111/j.1365-2435.2008.01523.x · Cited by 98 · see citing works
Contreras-Padilla, M., Pérez-Torrero, E., Hernández-Urbiola, M. I., Hernández-Quevedo, G., Real, A. D., Rivera-Muñoz, E. M., & Rodríguez-García, M. E. (2010) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2010.03.028 · Cited by 95 · see citing works
Purification and characterization of formyl-coenzyme A transferase from Oxalobacter formigenes
Baetz, A. L., & Allison, M. J. (1990) · Journal of Bacteriology · doi:10.1128/jb.172.7.3537-3540.1990 · Cited by 93 · see citing works
Oxalate‐Degrading Enterococcus faecalis
Hokama, S., Honma, Y., Toma, C., & Ogawa, Y. (2000) · Microbiology and Immunology · doi:10.1111/j.1348-0421.2000.tb02489.x · Cited by 89 · see citing works
Miller, A. W., Kohl, K. D., & Dearing, M. D. (2013) · Applied and Environmental Microbiology · doi:10.1128/aem.03742-13 · Cited by 89 · see citing works
Self-citationAzcárate-Peril, M. A., Bruno-Bárcena, J. M., Hassan, H. M., & Klaenhammer, T. R. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.72.3.1891-1899.2006 · Cited by 88 · see citing works
The Roles and Mechanisms of Intestinal Oxalate Transport in Oxalate Homeostasis
Hatch, M., & Freel, R. W. (2008) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2008.01.007 · Cited by 86 · see citing works
SIDHU, H., ENATSKA, L., Ogden, S., WILLIAMS, W., ALLISON, M., & Peck, A. B. (1997) · Molecular Diagnosis · doi:10.1016/s1084-8592(97)80015-x · Cited by 82 · see citing works
Turroni, S., Bendazzoli, C., Dipalo, S., Candela, M., Vitali, B., Gotti, R., & Brigidi, P. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.00844-10 · Cited by 81 · see citing works
Calcium oxalate crystals in leaves ofPancratiumsickenbergeri: constitutive or induced defence?
Ruiz, N., Ward, D., & Saltz, D. (2002) · Functional Ecology · doi:10.1046/j.0269-8463.2001.00594.x · Cited by 81 · see citing works
Oxalate Degradation by Microbes of the Large Bowel of Herbivores: The Effect of Dietary Oxalate
Allison, M. J., & Cook, H. M. (1981) · Science · doi:10.1126/science.7221555 · Cited by 80 · see citing works
Role of Dietary Intake and Intestinal Absorption of Oxalate in Calcium Stone Formation
JAEGER, P., & Robertson, W. G. (2004) · Nephron Physiology · doi:10.1159/000080266 · Cited by 79 · see citing works
Factors Related to Colonization with Oxalobacter formigenes in U.S. Adults
Kelly, J. P., Curhan, G. C., Cave, D. R., Anderson, T. E., & Kaufman, D. W. (2011) · Journal of Endourology · doi:10.1089/end.2010.0462 · Cited by 71 · see citing works
Halogeton Poisoning of Sheep: Effect Of High Level Oxalate Intake
James, L. F., & Butcher, J. E. (1972) · Journal of Animal Science · doi:10.2527/jas1972.3561233x · Cited by 70 · see citing works
Knight, J. L., Deora, R., Assimos, D. G., & Holmes, R. P. (2013) · Urolithiasis · doi:10.1007/s00240-013-0566-7 · Cited by 67 · see citing works
Oxalate Metabolism in the Pack Rat, Sand Rat, Hamster, and White Rat
Shirley, E. K., & Schmidt‐Nielsen, K. (1967) · Journal of Nutrition · doi:10.1093/jn/91.4.496 · Cited by 66 · see citing works
Kharlamb, V., Schelker, J., François, F., Jiang, J., Holmes, R. P., & Goldfarb, D. S. (2011) · Journal of Endourology · doi:10.1089/end.2011.0243 · Cited by 66 · see citing works
Probiotics in the Prevention and Treatment of Gastrointestinal Infections
Huebner, E. S., & Surawicz, C. M. (2006) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2006.03.005 · Cited by 64 · see citing works
Role of gut microbiota in Crohn’s disease
Baker, P., Love, D. R., & Ferguson, L. R. (2009) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/egh.09.47 · Cited by 63 · see citing works
The relation of clinical catastrophes, endogenous oxalate production, and urolithiasis
Conyers, R. A. J., Bais, R., & Rofe, A. M. (1990) · Clinical Chemistry · doi:10.1093/clinchem/36.10.1717 · Cited by 61 · see citing works
Sensitivity of Human Strains of Oxalobacter formigenes to Commonly Prescribed Antibiotics
Lange, J. N., Wood, K. D., Wong, H., Otto, R., Mufarrij, P., Knight, J. L., Akpınar, H., Holmes, R. P., & Assimos, D. G. (2012) · Urology · doi:10.1016/j.urology.2011.11.017 · Cited by 60 · see citing works
Macholz, R. M. (1988) · Food / Nahrung · doi:10.1002/food.19880321032 · Cited by 59 · see citing works
Microbial degradation of oxalate in the gastrointestinal tracts of rats
Daniel, S. L., Hartman, P. A., & Allison, M. J. (1987) · Applied and Environmental Microbiology · doi:10.1128/aem.53.8.1793-1797.1987 · Cited by 58 · see citing works
AGXT Gene Mutations and Their Influence on Clinical Heterogeneity of Type 1 Primary Hyperoxaluria
Amoroso, A., Pirulli, D., Florian, F., Puzzer, D., Boniotto, M., Crovella, S., Zezlina, S., Spanò, A., Mazzola, G. A., Savoldi, S., et al. (2001) · Journal of the American Society of Nephrology · doi:10.1681/asn.v12102072 · Cited by 57 · see citing works
Ferraz, R. R. N., Marques, N., Froeder, L., Menon, V. B., Siliano, P. R., Baxmann, A. C., & Heilberg, I. P. (2009) · Urological Research · doi:10.1007/s00240-009-0177-5 · Cited by 54 · see citing works
Absorption of Calcium Oxalate Does Not Require Dissociation in Rats
Hanes, D. A., Weaver, C. M., Heaney, R. P., & Wastney, M. E. (1999) · Journal of Nutrition · doi:10.1093/jn/129.1.170 · Cited by 52 · see citing works
Sasaki, E., Shimada, T., Osawa, R., Nishitani, Y., Spring, S., & Lang, E. (2005) · Systematic and Applied Microbiology · doi:10.1016/j.syapm.2005.01.005 · Cited by 51 · see citing works
Duncan, A. J., Frutos, P., & Young, S. A. (1997) · Animal Science · doi:10.1017/s135772980000864x · Cited by 50 · see citing works
Thermodynamic modeling of crystal deposition in humans
Königsberger, E., & Königsberger, L.-C. (2001) · Pure and Applied Chemistry · doi:10.1351/pac200173050785 · Cited by 49 · see citing works
Oxalate degradation by intestinal lactic acid bacteria in dogs and cats
Weese, J. S., Weese, H. E., Yuricek, L., & Rousseau, J. (2004) · Veterinary Microbiology · doi:10.1016/j.vetmic.2004.03.017 · Cited by 45 · see citing works
Chung, W.-G., Roh, H., Kim, H.-M., & Cha, Y.-N. (1998) · Chemico-Biological Interactions · doi:10.1016/s0009-2797(97)00109-9 · Cited by 42 · see citing works
Reduction of Oxalate Content of Foods by the Oxalate Degrading Bacterium, Eubacterium Lentum WYH‐1
Itô, H., Miura, N., Masai, M., Yamamoto, K., & Hara, T. (1996) · International Journal of Urology · doi:10.1111/j.1442-2042.1996.tb00626.x · Cited by 40 · see citing works
Prevention of nephrolithiasis by Lactobacillus in stone-forming rats: a preliminary study
Kwak, C. H., Jeong, B. C., Ku, J. H., Kim, H. H., Lee, J. Y., Huh, C. S., Baek, Y. J., & Lee, S. E. (2006) · Urological Research · doi:10.1007/s00240-006-0054-4 · Cited by 39 · see citing works
Caspary, W. F., Tönissen, J., & Lankisch, P. G. (1977) · PubMed · Cited by 37 · see citing works
A Pharm-Ecological Perspective of Terrestrial and Aquatic Plant-Herbivore Interactions
Forbey, J. S., Dearing, M. D., Gross, E. M., Orians, C. M., Sotka, E. E., & Foley, W. J. (2013) · Journal of Chemical Ecology · doi:10.1007/s10886-013-0267-2 · Cited by 35 · see citing works
Kuhner, C. H., Hartman, P. A., & Allison, M. J. (1996) · Applied and Environmental Microbiology · doi:10.1128/aem.62.7.2494-2500.1996 · Cited by 32 · see citing works
Lung, H.-Y., Cornelius, J., & Peck, A. B. (1991) · American Journal of Kidney Diseases · doi:10.1016/s0272-6386(12)80627-5 · Cited by 27 · see citing works
Metabolic Teamwork between Gut Microbes and Hosts
Karasov, W. H., & Carey, H. V. (2009) · Microbe Magazine · doi:10.1128/microbe.4.323.1 · Cited by 27 · see citing works
Oxalate digestibility in Neotoma albigula and Neotoma mexicana
Justice, K. E. (1985) · Oecologia · doi:10.1007/bf00384290 · Cited by 26 · see citing works
Oxalate-degrading capacities of lactic acid bacteria in canine feces
Ren, Z., Pan, C., Jiang, L., Wu, C., Liu, Y., Zhong, Z., Ran, L., Ren, F., Chen, X., Wang, Y., et al. (2011) · Veterinary Microbiology · doi:10.1016/j.vetmic.2011.05.003 · Cited by 24 · see citing works
Oxalate‐degrading Providencia rettgeri isolated from human stools
Hokama, S., Toma, C., Iwanaga, M., Morozumi, M., Sugaya, K., & Ogawa, Y. (2005) · International Journal of Urology · doi:10.1111/j.1442-2042.2005.01083.x · Cited by 24 · see citing works
Hiura, T., Hashidoko, Y., Kobayashi, Y., & Tahara, S. (2009) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2009.09.015 · Cited by 22 · see citing works
Impact of oxalic acid on rumen function and bacterial community in sheep
Belenguer, Á., Benbati, M., Hervás, G., Toral, P. G., Yáñez-Ruíz, D. R., & Frutos, P. (2013) · animal · doi:10.1017/s1751731112002455 · Cited by 17 · see citing works
Palgi, N., Taleisnik, H., & Pinshow, B. (2007) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2007.11.010 · Cited by 13 · see citing works
Oxalate balance in fat sand rats feeding on high and low calcium diets
Palgi, N., Ronen, Z., & Pinshow, B. (2008) · Journal of Comparative Physiology B · doi:10.1007/s00360-008-0252-1 · Cited by 13 · see citing works
Acute oxalate intoxication associated to ingestion of eshnan (Seidlitzia rosmarinus) in sheep
Aslani, M. R., Movassaghi, A. R., Najarnezhad, V., Pirouz, H. J., & Heidarpour, M. (2011) · Tropical Animal Health and Production · doi:10.1007/s11250-011-9818-0 · Cited by 11 · see citing works
Flagged first, then by citations
1 of the 108 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Recent advances on the mechanisms of kidney stone formation (Review)
Wang, Z., Zhang, Y., Zhang, J., Deng, Q., & Liang, H. (2021) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2021.4982 · Cited by 290 · see citing works
Host-microbial interactions in the metabolism of therapeutic and diet-derived xenobiotics
Carmody, R. N., & Turnbaugh, P. J. (2014) · Journal of Clinical Investigation · doi:10.1172/jci72335 · Cited by 268 · see citing works
Ticinesi, A., Milani, C., Guerra, A., Allegri, F., Lauretani, F., Nouvenne, A., Mancabelli, L., Lugli, G. A., Turroni, F., Duranti, S., et al. (2018) · Gut · doi:10.1136/gutjnl-2017-315734 · Cited by 186 · see citing works
Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt
Weljie, A. M., Meerlo, P., Goel, N., Sengupta, A., Kayser, M. S., Abel, T., Birnbaum, M. J., Dinges, D. F., & Sehgal, A. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1417432112 · Cited by 158 · see citing works
Plant-Based Fermented Beverages: Nutritional Composition, Sensory Properties, and Health Benefits
†, B. H.-F., †, E. D. J.-J., Cabrera-Hidalgo, A. J., Sandoval-Castilla, O., Espinosa‐Solares, T., González-Reza, R. M., Zambrano‐Zaragoza, M. L., Liceaga, A. M., & Aguilar-Toalá, J. E. (2024) · Foods · doi:10.3390/foods13060844 · Cited by 149 · see citing works
Stanford, J., Charlton, K. E., Stefoska‐Needham, A., Ibrahim, R., & Lambert, K. (2020) · BMC Nephrology · doi:10.1186/s12882-020-01805-w · Cited by 118 · see citing works
Ermer, T., Nazzal, L., Tio, M. C., Waikar, S. S., Aronson, P. S., & Knauf, F. (2022) · Nature Reviews Nephrology · doi:10.1038/s41581-022-00643-3 · Cited by 115 · see citing works
Kohl, K. D., & Dearing, M. D. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01165 · Cited by 98 · see citing works
Ticinesi, A., Nouvenne, A., Chiussi, G., Castaldo, G., Guerra, A., & Meschi, T. (2020) · Nutrients · doi:10.3390/nu12020548 · Cited by 99 · see citing works
Mechanisms of the intestinal and urinary microbiome in kidney stone disease
Miller, A. W., Penniston, K. L., Fitzpatrick, K., Agudelo, J., Tasian, G., & Lange, D. (2022) · Nature Reviews Urology · doi:10.1038/s41585-022-00647-5 · Cited by 89 · see citing works
Self-citationSchlemper, T. R., van Veen, J. A., & Kuramae, E. E. (2017) · Microbial Ecology · doi:10.1007/s00248-017-1108-6 · Cited by 82 · see citing works
Liu, M., Koh, H., Kurtz, Z. D., Battaglia, T., PeBenito, A., Li, H., Nazzal, L., & Blaser, M. J. (2017) · Microbiome · doi:10.1186/s40168-017-0316-0 · Cited by 81 · see citing works
Denburg, M., Koepsell, K., Lee, J., Gerber, J. S., Bittinger, K. L., & Tasian, G. E. (2020) · Journal of the American Society of Nephrology · doi:10.1681/asn.2019101131 · Cited by 78 · see citing works
Chamberlain, C. A., Hatch, M., & Garrett, T. J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0222393 · Cited by 69 · see citing works
Diversity and ecology of oxalotrophic bacteria
Hervé, V., Junier, T., Bindschedler, S., Verrecchia, É. P., & Junier, P. (2016) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-015-1982-3 · Cited by 68 · see citing works
Probiotics for prevention of urinary stones
Lieske, J. C. (2017) · Annals of Translational Medicine · doi:10.21037/atm.2016.11.86 · Cited by 59 · see citing works
Role of gut microbiota against calcium oxalate
Sadaf, H., Raza, S. I., & Hassan, S. W. (2017) · Microbial Pathogenesis · doi:10.1016/j.micpath.2017.06.009 · Cited by 58 · see citing works
Kostovcikova, K., Whittamore, J. M., & Hatch, M. (2014) · Urolithiasis · doi:10.1007/s00240-014-0728-2 · Cited by 57 · see citing works
Fecal Microbiota and Metabolome in a Mouse Model of Spontaneous Chronic Colitis
Robinson, A. M., Gondalia, S. V., Karpe, A. V., Eri, R. D., Beale, D. J., Morrison, P. D., Palombo, E. A., & Nurgali, K. (2016) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000970 · Cited by 53 · see citing works
Amin, M. R., Asplin, J. R., Jung, D., Bashir, M. E. H., Alshaikh, A., Ratakonda, S., Sharma, S., Jeon, S., Granja, I., Matern, D., et al. (2018) · Kidney International · doi:10.1016/j.kint.2017.11.011 · Cited by 55 · see citing works
Calcium Oxalate Urolithiasis: A Case of Missing Microbes?
Batagello, C., Monga, M., & Miller, A. W. (2018) · Journal of Endourology · doi:10.1089/end.2018.0294 · Cited by 48 · see citing works
Self-citationWei, Z., Cui, Y., Tian, L., Liu, Y., Yu, Y., Jin, X., Li, H., Wang, K., & Sun, Q. (2021) · The FASEB Journal · doi:10.1096/fj.202100887rr · Cited by 47 · see citing works
Complementary and Integrative Therapies for Lower Urinary Tract Diseases
Raditic, D. (2015) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/j.cvsm.2015.02.009 · Cited by 44 · see citing works
Multi-site microbiota alteration is a hallmark of kidney stone formation
Al, K. F., Joris, B. R., Daisley, B. A., Chmiel, J. A., Bjazevic, J., Reid, G., Gloor, G. B., Denstedt, J. D., RAZVI, H. A., & Burton, J. P. (2023) · Microbiome · doi:10.1186/s40168-023-01703-x · Cited by 42 · see citing works
Putative mechanisms of kiwifruit on maintenance of normal gastrointestinal function
Bayer, S. B., Gearry, R. B., & Drummond, L. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1327841 · Cited by 40 · see citing works
Loss of function dysbiosis associated with antibiotics and high fat, high sugar diet
Miller, A. W., Orr, T. J., Dearing, M. D., & Monga, M. (2019) · The ISME Journal · doi:10.1038/s41396-019-0357-4 · Cited by 38 · see citing works
Self-citationPeck, A. B., Canales, B. K., & Nguyen, C. Q. (2015) · Urolithiasis · doi:10.1007/s00240-015-0845-6 · Cited by 37 · see citing works
Kohl, K. D., Oakeson, K. F., Orr, T. J., Miller, A. W., Forbey, J. S., Phillips, C. D., Dale, C., Weiss, R. B., & Dearing, M. D. (2018) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiy184 · Cited by 37 · see citing works
Self-citationPanyushkina, A., Babenko, V. V., Nikitina, A. S., Selezneva, O. V., Tsaplina, I. A., Letarova, M. A., Kostryukova, E., & Letarov, A. V. (2019) · Scientific Reports · doi:10.1038/s41598-019-51486-1 · Cited by 37 · see citing works
Karamad, D., Khosravi‐Darani, K., Khaneghah, A. M., & Miller, A. W. (2022) · Foods · doi:10.3390/foods11182876 · Cited by 35 · see citing works
Self-citationOxalate-Degrading Bacillus subtilis Mitigates Urolithiasis in a Drosophila melanogaster Model
Al, K. F., Daisley, B. A., Chanyi, R. M., Bjazevic, J., RAZVI, H. A., Reid, G., & Burton, J. P. (2020) · mSphere · doi:10.1128/msphere.00498-20 · Cited by 30 · see citing works
Akter, S., Netzel, M. E., Tinggi, U., Fletcher, M. T., Osborne, S. A., & Sultanbawa, Y. F. (2020) · Frontiers in Nutrition · doi:10.3389/fnut.2020.598219 · Cited by 27 · see citing works
Gut Microbiota as a Source of Uremic Toxins
Popkov, V. A., Zharikova, A. A., Demchenko, E. A., Andrianova, N. V., Zorov, D. B., & Plotnikov, E. Y. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23010483 · Cited by 26 · see citing works
A Metagenomic Insight Into the Human Microbiome
Saxena, R., & Sharma, V. K. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-420196-5.00009-5 · Cited by 25 · see citing works
Stepanova, N. (2023) · Biomedicines · doi:10.3390/biomedicines11061654 · Cited by 24 · see citing works
Jaunet‐Lahary, T., Shimamura, T., Hayashi, M., Nomura, N., Hirasawa, K., Shimizu, T. M., Yamashita, M., Tsutsumi, N., Suehiro, Y., Kojima, K., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36883-5 · Cited by 23 · see citing works
Hunthai, S., Usawachintachit, M., Taweevisit, M., Srisa‐Art, M., Anegkamol, W., Tosukhowong, P., Rattanachaisit, P., Chuaypen, N., & Dissayabutra, T. (2024) · Scientific Reports · doi:10.1038/s41598-024-72694-4 · Cited by 23 · see citing works
Demonstrating the role of symbionts in mediating detoxification in herbivores
Dearing, M. D., Kaltenpoth, M., & Gershenzon, J. (2022) · Symbiosis · doi:10.1007/s13199-022-00863-y · Cited by 20 · see citing works
Choy, W. H., Adler, A., Morgan‐Lang, C., Gough, E. K., Hallam, S., Manges, A. R., Chew, B. H., Penniston, K. L., Miller, A. W., & Lange, D. (2024) · Urolithiasis · doi:10.1007/s00240-024-01534-x · Cited by 20 · see citing works
Self-citationActivity of probiotics from food origin for oxalate degradation
Soliman, N. R., Effat, B., Mehanna, N. S., Tawfik, N. F., & Ibrahim, M. K. (2021) · Archives of Microbiology · doi:10.1007/s00203-021-02484-3 · Cited by 19 · see citing works
The rhizomicrobiomes of wild and cultivated crops react differently to fungicides
Shi, S., Tian, L., Xu, S., Ji, L., Nasir, F., Li, X., Song, Z., & Tian, C. (2018) · Archives of Microbiology · doi:10.1007/s00203-018-1586-z · Cited by 15 · see citing works
Mohottige, T. N. W., Ginige, M. P., Kaksonen, A. H., Sarukkalige, R., & Cheng, K. Y. (2017) · Bioresource Technology · doi:10.1016/j.biortech.2017.11.009 · Cited by 15 · see citing works
Kidney stones: Mechanism of formation, pathogenesis and possible treatments
Gupta, S., & Sk, S. (2018) · Cited by 13 · see citing works
Li, D., Li, Z., & Liu, W. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1655808 · Cited by 12 · see citing works
Millán, F., Rubio, L. S., Girón, I., Sánchez-Martín, F. M., Emiliani, E., & Angerri, O. (2020) · Urolithiasis · doi:10.1007/s00240-020-01181-y · Cited by 12 · see citing works
Gut and Urinary Microbiota in Cats with Kidney Stones
Joubran, P., Roux, F., Sérino, M., & Deschamps, J. (2024) · Microorganisms · doi:10.3390/microorganisms12061098 · Cited by 11 · see citing works
Hinojosa-Gonzalez, D. E., & Eisner, B. H. (2022) · Urologic Clinics of North America · doi:10.1016/j.ucl.2022.09.004 · Cited by 10 · see citing works
Suryavanshi, M. V., Franklin, A., Fargue, S., Assimos, D. G., Knight, J. L., & Miller, A. W. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2562337 · Cited by 9 · see citing works
Self-citationOxalate Content of Enteral Nutrition Formulas
Penniston, K. L., Palmer, E. A., Medenwald, R. J., Johnson, S., John, L. M., Beshensky, D. J., & Saeed, I. A. M. (2019) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000002472 · Cited by 9 · see citing works
Ghate, S. D., Shastry, R. P., & Rekha, P. D. (2021) · Ecological Genetics and Genomics · doi:10.1016/j.egg.2021.100102 · Cited by 8 · see citing works
Wang, X., Bhutani, G., Vaughan, L. E., Enders, F., Haskic, Z., Milliner, D. S., & Lieske, J. C. (2020) · BMC Nephrology · doi:10.1186/s12882-020-01783-z · Cited by 8 · see citing works
Complex system modeling reveals oxalate homeostasis is driven by diverse oxalate-degrading bacteriaPreprint
Mukherjee, S., Batagello, C., Adler, A., Agudelo, J., Zampini, A. M., Suryavanshi, M. V., Nguyen, A. H., Orr, T. J., Dearing, M. D., Monga, M., et al. (2025) · eLife · doi:10.7554/elife.104121 · Cited by 8 · see citing works
Self-citationXia, D., Nie, W., Li, X., Finlay, R. D., & Lian, B. (2024) · Scientific Reports · doi:10.1038/s41598-024-74939-8 · Cited by 7 · see citing works
Therapeutic Applications of Microbial Enzymes in the Management of Kidney Stone Diseases
Gupta, S., & Kanwar, S. S. (2020) · Microorganisms for sustainability · doi:10.1007/978-981-15-1710-5_13 · Cited by 7 · see citing works
Chamberlain, C. A., Hatch, M., & Garrett, T. J. (2020) · Metabolites · doi:10.3390/metabo10100405 · Cited by 7 · see citing works
Malaviya, R., Pandey, A., & Yadav, N. (2021) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.15850 · Cited by 7 · see citing works
Liu, T., Cui, X., Chen, J., Wang, J., Wu, S., Zhang, M., Tang, F., Xiao, Y., Ren, J., Zhang, Z., et al. (2025) · Advanced Materials · doi:10.1002/adma.202508773 · Cited by 6 · see citing works
Stepanova, N., Tolstanova, G. M., Aleksandrova, I., Korol, L., Dovbynchuk, T., Driianska, V., & Savchenko, S. (2023) · Medicina · doi:10.3390/medicina59122189 · Cited by 6 · see citing works
Yan, X., Shao, X., Zeng, T., Zhang, Q., Deng, J., & Xie, J. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1540688 · Cited by 6 · see citing works
Human microbiome studies in Korea
Choi, S.-M., Cho, S., & Yi, H. (2016) · Allergy Asthma & Respiratory Disease · doi:10.4168/aard.2016.4.5.311 · Cited by 6 · see citing works
Gaur, A., Kumar, P., & Kumar, D. (2025) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.70212 · Cited by 5 · see citing works
Mijnendonckx, K., Gompel, A. V., Coninx, I., Bleyen, N., & Leys, N. (2020) · Applied Geochemistry · doi:10.1016/j.apgeochem.2020.104525 · Cited by 5 · see citing works
Zhou, Q., Guo, Q., Cui, X., Meng, T., Pang, Z., Wang, S., Chen, H., Lu, M., Liu, G., Huang, C., et al. (2025) · iMetaOmics. · doi:10.1002/imo2.70051 · Cited by 4 · see citing works
Nonpharmacologic Methods of Stone Risk Reduction
Penniston, K. L. (2025) · Urologic Clinics of North America · doi:10.1016/j.ucl.2025.04.003 · Cited by 4 · see citing works
Microbiome dynamics of disease suppresive soils
Expósito, R. G. (2017) · doi:10.18174/412539 · Cited by 4 · see citing works
Predicting probiotic success: lessons from Oxalobacter and oxalate metabolism
Suryavanshi, M. V., Mukherjee, S., & Miller, A. W. (2026) · npj Biofilms and Microbiomes · doi:10.1038/s41522-025-00896-3 · Cited by 3 · see citing works
Self-citationImpact of the Human Microbiome on Nephrolithiasis
Jung, H. D., & Lee, J. Y. (2021) · Urogenital Tract Infection · doi:10.14777/uti.2021.16.2.25 · Cited by 3 · see citing works
Suryavanshi, M. V., Bhute, S. S., Bharti, N., Pawar, K. D., & Shouche, Y. S. (2016) · Journal of Pure and Applied Microbiology · doi:10.22207/jpam.10.3.42 · Cited by 3 · see citing works
Advances in Probiotics for Health and Nutrition
Zambare, V., Din, M. F. M., Gupta, P., & Prajapati, B. G. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.104299 · Cited by 2 · see citing works
Demircan, T., Gül, S., & Taşçı, E. A. (2024) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2024.0075 · Cited by 2 · see citing works
Wu, J. (2025) · BMC Public Health · doi:10.1186/s12889-025-24292-w · Cited by 2 · see citing works
Acidification-driven mineral weathering ability of bacteria: genetics, conservation, and regulations
Uroz, S., Nouche, C. B., Bouche, S., & Turpault, M. (2026) · Trends in Microbiology · doi:10.1016/j.tim.2026.05.004 · Cited by 2 · see citing works
Changes in the rumen bacterial microbiome of cattle exposed to ponderosa pine needles
Welch, K. D., Stonecipher, C. A., Gardner, D. R., Cook, D., & Pfister, J. A. (2017) · Journal of Animal Science · doi:10.2527/jas.2016.1228 · Cited by 2 · see citing works
"Oxalate Degrading Lactic Acid Bacteria in Prevention and Management of Kidney Stone"
Suman, D. (2021) · Open Access Journal of Complementary & Alternative Medicine · doi:10.32474/oajcam.2021.03.000172 · Cited by 2 · see citing works
Guerfali, M. M., Hamden, H., Charaabi, K., Fadhl, S., Mosbah, A., & Cherif, A. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.110126 · Cited by 2 · see citing works
Nutraceuticals in Genitourinary Maladies
Coppock, R. W. (2019) · Springer eBooks · doi:10.1007/978-3-030-04624-8_33 · Cited by 2 · see citing works
The Role of Bacteria in Non-infection Stone Formation
Dornbier, R. A., Bajic, P., Schwaderer, A. L., & Wolfe, A. J. (2019) · Springer eBooks · doi:10.1007/978-3-030-17542-9_16 · Cited by 2 · see citing works
Peng, L., Zhou, X., Liu, J., Chen, J., Zhang, J., Tan, F., Li, B., Liang, Y., Li, Q., Chang, Z., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1757548 · Cited by 1 · see citing works
Li, Y., He, N., Chang, M., & Wang, Y. (2026) · Biology · doi:10.3390/biology15171447 · Cited by 1 · see citing works
Pareek, N. (2019) · The Keep (Eastern Illinois University) · Cited by 1 · see citing works
Biocontrol of Aspergillus niger in 3D-lung cell tissues by oxalotrophic bacteriaPreprint
Palmieri, F., Palmieri, I., Noormamode, N., Estoppey, A., Ishak, M. O., Kelliher, J. M., Vallat, A., Iyer, R. S., Bindschedler, S., Davenport, K. W., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.08.20.259929 · Cited by 1 · see citing works
[How the studies of the reproduction process contributed to the appearance of neuroendocrinology].
Zárate, A., Saucedo, R., & Hernández, M. (2006) · PubMed · Cited by 1 · see citing works
Palmieri, F., Trompette, A., Shanmuganathan, A., Bouchard, A., Pernot, J., Junier, T., Kelliher, J. M., Chain, P., Harris, J. F., Vallat, A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.27.645790 · Cited by 1 · see citing works
Could Microbiota Edit Oxalate Nephrolithiasis’ Story?
Merra, G., Gualtieri, P., LORENZO, A. D., Capacci, A., Frank, G., Dri, M., Renzo, L. D., & Marchetti, M. (2023) · Current Nutrition & Food Science · doi:10.2174/1573401319666230601143942
Microbial Biopharmaceuticals in Urolithiasis Management and Treatment
Gupta, S., & Singh, K. S. (2023) · Springer eBooks · doi:10.1007/978-981-99-3126-2_30
Various Methods of Reducing Calcium Oxalate Levels in Tubers: a Review
Quddus, A. A., Hambali, E., Rahayuningsih, M., Kartika, I. A., & Budijanto, S. (1970) · Jurnal Biota · doi:10.19109/biota.v10i1.20473
Human microbiome and genito-urinary disorders
Bad-ang, M. T., Jayakumar, D., Bansal, A., Kolkar, K., Joseph, K. S. J., Deshpande, A. A., Wee, A. M. G., & Sivaraj, A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15435-5.00012-8
Complex system modelling reveals oxalate homeostasis is driven by diverse oxalate-degrading bacteriaPreprint
Mukherjee, S., Batagello, C., Adler, A., Agudelo, J., Zampini, A. M., Suryavanshi, M. V., Nguyen, A. H., Orr, T. J., Dearing, M. D., Monga, M., et al. (2025) · eLife · doi:10.7554/elife.104121.1
Self-citationComplex system modelling reveals oxalate homeostasis is driven by diverse oxalate-degrading bacteriaPreprint
Mukherjee, S., Batagello, C., Adler, A., Agudelo, J., Zampini, A. M., Suryavanshi, M. V., Nguyen, A. H., Orr, T. J., Dearing, M. D., Monga, M., et al. (2025) · eLife · doi:10.7554/elife.104121.2
Self-citationPurnama, E. R., Makwa, J., & Muttaqien, Y. V. (2024) · Journal of Biotropical Research and Nature Technology · doi:10.52850/borneo.v3i1.16239
Wang, X., Bhutani, G., Vaughan, L. E., Enders, F., Haskic, Z., Milliner, D. S., & Lieske, J. C. (2020) · Figshare · doi:10.6084/m9.figshare.12133824
Wang, X., Bhutani, G., Vaughan, L. E., Enders, F., Haskic, Z., Milliner, D., & Lieske, J. C. (2020) · Figshare · doi:10.6084/m9.figshare.12133830
Rajan, F. V., & Bucking, C. (2026) · PLoS ONE · doi:10.1371/journal.pone.0347147
Ru, Y., Yu, Y., Liu, C., Liu, Y., Liu, D., Chen, R., Chen, X., Bai, X., Jiang, T., & Duan, J. (2026) · BMC Microbiology · doi:10.1186/s12866-026-05033-4
Vosoughi, P., Najafi, M. B. H., Khosravi‐Darani, K., & Vosough, P. R. (2026) · Journal of Basic Microbiology · doi:10.1002/jobm.70171
Zhang, W., Ren, Y., Liu, X., Liu, X., Tang, W., Ju, Y., Yu, W., Guo, Z., Qiao, H., Yu, X., et al. (2026) · Natural Product Communications · doi:10.1177/1934578x261451343
Sarita, Yadav, S., Manjeet, Peddireddy, V., & Sharma, K. P. (2026) · Discover Food · doi:10.1007/s44187-026-01041-5
Salvador, A. C., Khaled, Z. W., Awad, A., Huan, B., Lau, G. W., Silverstein, S., Weaver, D., Zhu, L., Bantumilli, S., Thomas, V., et al. (2026) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2026.101861
Jin, X., Li, J., Zhao, Y., Xu, K., Wang, Y., Bai, S., Liu, Y., & Li, Z. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1893492
- Authors
- Miller, A., & Dearing, D.
- Affiliations
- University of Utah (US)
- Department of Biology, University of Utah, 257 South 1400 East, Salt Lake City, UT 84112, USA
- Corresponding author
- Miller, Aaron
- Venue
- Pathogens
- Publisher
- MDPI AG
- Published
- 2013-12-06
- Volume
- 2
- Issue
- 4
- Pages
- 636-652
- ISSN
- 2076-0817 (ISSN-L)
- PMC
- PMC4235702
- OpenAlex
- W2152616728
- Cited by
- 101
- References
- 108
- Citations by year
- 2026: 12 · 2025: 12 · 2024: 9 · 2023: 8 · 2022: 6 · 2021: 7 · 2020: 13 · 2019: 7 · 2018: 6 · 2017: 8 · 2016: 6 · 2015: 3 · 2014: 2
- FWCI
- 0.35
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Pathogens (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Science Foundation (1342615)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Kidney Stones and Urolithiasis Treatments
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- oxalate-degrading bacteria, gut microbiota, oxalate degradation, host-microbe interactions, plant secondary metabolites, oxalate metabolism, microbial interactions, oxalate toxicity, microbial ecology
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review