Potential of Industrial Hemp for Phytoremediation of Heavy Metals
Open accessAbstract
The accumulation of anthropogenic heavy metals in soil is a major form of pollution. Such potentially toxic elements are nonbiodegradable and persist for many years as threats to human and environmental health. Traditional forms of remediation are costly and potentially damaging to the land. An alternative strategy is phytoremediation, where plants are used to capture metals from the environment. Industrial hemp (Cannabis sativa) is a promising candidate for phytoremediation. Hemp has deep roots and is tolerant to the accumulation of different metals. In addition, the crop biomass has many potential commercial uses after harvesting is completed. Furthermore, the recent availability of an annotated genome sequence provides a powerful tool for the bioengineering of C. sativa for better phytoremediation.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
As a result, roots, leaves, and stalks from phytoremediation are not used to make food or personal care products but may be used to make biofuel, paper, fabric, and construction materials.
“As a result, these parts are not used to make food or personal care products but may be used to make biofuel, paper, fabric, and construction materials (Placido and Lee 2022; Vandenhove and Van Hees 2005).”
From A critical review of industrial fiber hemp anatomy, agronomic practices, and valorization into sustainable bioproducts (2025) · cites this paper as Placido and Lee 2022
Section 2.2 says toxins can accumulate in roots, leaves, and stalks; it then says leaves are not used for food or personal care products, while stalks can be used for building materials, paper, cloth, and biofuel. The claim extends those restrictions and potential uses to all three plant parts, which the passage does not establish. (LLM, conf=0.87)
Experimental — accuracy not yet measuredThe industrial hemp plant has deep roots, 45 to 90 cm long, which helps in phytoremediation of heavy metals in the soil, such as chromium, iron, and cadmium.
“The industrial hemp plant has deep roots, 45 to 90 cm long, which helps in phytoremediation of heavy metals in the soil, such as chromium, iron, and cadmium (Placido and Lee 2022; Xu et al. 2022).”
From A critical review of industrial fiber hemp anatomy, agronomic practices, and valorization into sustainable bioproducts (2025) · cites this paper as Placido and Lee 2022
The Introduction states that hemp has roots 45–90 cm deep and that its deep roots help it extract metals from soil. Sections 2.3 and 2.7 discuss chromium and cadmium uptake, respectively. Our copy does not establish iron phytoremediation by hemp (searched: iron and iron uptake). (LLM, conf=0.88)
Experimental — accuracy not yet measuredHemp has potential in phytoremediation by absorbing pollutants or heavy metals via its deep root system, aiding land reclamation and environmental remediation.
“Hemp has been recognized for its potential in phytoremediation, a process whereby plants can help detoxify contaminated soils by absorbing pollutants or heavy metals by its deep root system, thus aiding land reclamation and environmental remediation (Placido and Lee 2022).”
From A critical review of industrial fiber hemp anatomy, agronomic practices, and valorization into sustainable bioproducts (2025) · cites this paper as Placido and Lee 2022
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Industrial Hemp in North America: Production, Politics and Potential
Cherney, J., & Small, E. (2016) · Agronomy · doi:10.3390/agronomy6040058 · Cited by 328 · see citing works
Bañuelos, G., Terry, N., LeDuc, D. L., Pilon-Smits, E. A. H., & Mackey, B. (2005) · Environmental Science & Technology · doi:10.1021/es049035f · Cited by 226 · see citing works
Heavy metal tolerance and accumulation of Cd, Cr and Ni by Cannabis sativa L.
Citterio, S., Santagostino, A., Fumagalli, P., Prato, N., Ranalli, P., & Sgorbati, S. (2003) · Plant and Soil · doi:10.1023/a:1026113905129 · Cited by 189 · see citing works
Schröder, P., Beckers, B., Daniels, S., Gnädinger, F., Maestri, E., Marmiroli, N., Mench, M., Millan, R., Obermeier, M. M., Oustriere, N., et al. (2018) · Science of The Total Environment · doi:10.1016/j.scitotenv.2017.10.209 · Cited by 151 · see citing works
Tissue culture and Agrobacterium-mediated transformation of hemp (Cannabis sativa L.)
Feeney, M., & Punja, Z. K. (2003) · In Vitro Cellular & Developmental Biology - Plant · doi:10.1079/ivp2003454 · Cited by 110 · see citing works
Husain, R., Weeden, H., Bogush, D., Deguchi, M., Soliman, M., Potlakayala, S., Katam, R., Goldman, S., & Rudrabhatla, S. (2019) · PLOS ONE · doi:10.1371/journal.pone.0221570 · Cited by 91 · cited 1× · see citing works
“Hemp can take up high concentrations of cadmium, nickel, and lead from metalcontaminated environments, such as soil from abandoned mines [37].”
BackgroundUllah, R., Hadi, F., Ahmad, S., Jan, A. U., & Rongliang, Q. (2019) · Water, Air, & Soil Pollution · doi:10.1007/s11270-019-4089-x · Cited by 85 · see citing works
Stonehouse, G. C., McCarron, B. J., Guignardi, Z. S., El Mehdawi, A. F., Lima, L. W., Fakra, S. C., & Pilon-Smits, E. A. H. (2020) · Environmental Science & Technology · doi:10.1021/acs.est.9b07747 · Cited by 59 · see citing works
Khattab, M. M., & Dahman, Y. (2019) · Bioprocess and Biosystems Engineering · doi:10.1007/s00449-019-02109-6 · Cited by 38 · see citing works
Flagged first, then by citations
Research works printed but not linked: 81
- [1]Bañuelos G.S. Ajwa H.A. Trace elements in soils and plants: An overview J. Environ. Sci. Health Part A 1999 34 951 974 10.1080/10934529909376875 · DOI
- [2]Hou D. O’Connor D. Igalavithana A.D. Alessi D.S. Luo J. Tsang D.C.W. Sparks D.L. Yamauchi Y. Rinklebe J. Ok Y.S. Metal contamination and bioremediation of agricultural soils for food safety and sustainability Nat. Rev. Earth Environ. 2020 1 366 381 10.1038/s43017-020-0061-y · DOI · Paper page
- [3]Järup L. Hazards of heavy metal contamination Br. Med. Bull. 2003 68 167 182 10.1093/bmb/ldg032 14757716 · DOI · Paper page
- [4]Garbisu C. Alkorta I. Phytoextraction: A cost-effective plant-based technology for the removal of metals from the environment Bioresour. Technol. 2001 77 229 236 10.1016/S0960-8524(00)00108-5 11272009 · DOI
- [5]Cunningham S.D. Berti W.R. Remediation of contaminated soils with green plants: An overview Vitr. Cell. Dev. Biol. Plant 1993 29 207 212 10.1007/BF02632036 · DOI
- [6]Raskin I. Smith R.D. Salt D.E. Phytoremediation of metals: Using plants to remove pollutants from the environment Curr. Opin. Biotechnol. 1997 8 221 226 10.1016/S0958-1669(97)80106-1 9079727 · DOI
- [8]Băbău A.M.C. Micle V. Damian G.E. Sur I.M. Sustainable ecological restoration of sterile dumps using Robinia pseudoacacia Sustainability 2021 13 14021 10.3390/su132414021 · DOI
- [9]Kanwar V.S. Sharma A. Srivastav A.L. Rani L. Phytoremediation of toxic metals present in soil and water environment: A critical review Environ. Sci. Pollut. Res. 2020 27 44835 44860 10.1007/s11356-020-10713-3 32981020 · DOI
- [10]Küpper H. Jie Zhao F. McGrath S.P. Cellular compartmentation of zinc in leaves of the hyperaccumulator Thlaspi caerulescens Plant Physiol. 1999 119 305 312 10.1104/pp.119.1.305 9880373 PMC32233 · DOI
- [11]Sumiahadi A. Acar R. A review of phytoremediation technology: Heavy metals uptake by plants IOP Conf. Ser. Earth Environ. Sci. 2018 142 012023 10.1088/1755-1315/142/1/012023 · DOI
- [12]Vázquez M.D. Barceló J. Poschenrieder C. Mádico J. Hatton P. Baker A.J.M. Cope G.H. Localization of zinc and cadmium in Thlaspi caerulescens (Brassicaceae), a metallophyte that can hyperaccumulate both metals J. Plant Physiol. 1992 140 350 355 10.1016/S0176-1617(11)81091-6 · DOI
- [13]Vögeli-Lange R. Wagner G.J. Subcellular localization of cadmium and cadmium-binding peptides in tobacco leaves: Implication of a transport function for cadmium-binding peptides Plant Physiol. 1990 92 1086 1093 10.1104/pp.92.4.1086 16667375 PMC1062420 · DOI
- [15]Adesina I. Bhowmik A. Sharma H. Shahbazi A. A review on the current state of knowledge of growing conditions, agronomic soil health practices and utilities of hemp in the United States Agriculture 2020 10 129 10.3390/agriculture10040129 · DOI · Paper page
- [16]Hall J. Bhattarai S.P. Midmore D.J. Review of flowering control in industrial hemp J. Nat. Fibers 2012 9 23 36 10.1080/15440478.2012.651848 · DOI · Paper page
- [17]Amaducci S. Gusovius H.J. Hemp-cultivation, extraction and processing Industrial Applications of Natural Fibres: Structure, Properties and Technical Applications John Wiley & Sons Hoboken, NJ, USA 2010 109 134
- [19]Chundawat S.P.S. Beckham G.T. Himmel M.E. Dale B.E. Deconstruction of lignocellulosic biomass to fuels and chemicals Annu. Rev. Chem. Biomol. Eng. 2011 2 121 145 10.1146/annurev-chembioeng-061010-114205 22432613 · DOI · Paper page
- [20]Hu R. Lim J.-K. Fabrication and mechanical properties of completely biodegradable hemp fiber reinforced polylactic acid composites J. Compos. Mater. 2016 41 1655 1669 10.1177/0021998306069878 · DOI
- [21]Zhao J. Xu Y. Wang W. Griffin J. Roozeboom K. Wang D. Bioconversion of industrial hemp biomass for bioethanol production: A review Fuel 2020 281 118725 10.1016/j.fuel.2020.118725 · DOI
- [22]Das L. Liu E. Saeed A. Williams D.W. Hu H. Li C. Ray A.E. Shi J. Industrial hemp as a potential bioenergy crop in comparison with kenaf, switchgrass and biomass sorghum Bioresour. Technol. 2017 244 641 649 10.1016/j.biortech.2017.08.008 28810219 · DOI
- [23]Gunnarsson I.B. Kuglarz M. Karakashev D. Angelidaki I. Thermochemical pretreatments for enhancing succinic acid production from industrial hemp (Cannabis sativa L.) Bioresour. Technol. 2015 182 58 66 10.1016/j.biortech.2015.01.126 25682224 · DOI
- [24]Song H. Lee S.Y. Production of succinic acid by bacterial fermentation Enzym. Microb. Technol. 2006 39 352 361 10.1016/j.enzmictec.2005.11.043 · DOI
- [26]Salt D.E. Blaylock M. Kumar N.P.B.A. Dushenkov V. Ensley B.D. Chet I. Raskin I. Phytoremediation: A novel strategy for the removal of toxic metals from the environment using plants Nat. Biotechnol. 1995 13 468 474 10.1038/nbt0595-468 9634787 · DOI
- [27]Ku H. Wang H. Pattarachaiyakoop N. Trada M. A review on the tensile properties of natural fiber reinforced polymer composites Compos. Part B Eng. 2011 42 856 873 10.1016/j.compositesb.2011.01.010 · DOI
- [28]Musio S. Müssig J. Amaducci S. Optimizing hemp fiber production for high performance composite applications Front. Plant Sci. 2018 9 1702 10.3389/fpls.2018.01702 30532760 PMC6265480 · DOI · Paper page
- [29]Yan Z.L. Wang H. Lau K.T. Pather S. Zhang J.C. Lin G. Ding Y. Reinforcement of polypropylene with hemp fibres Compos. Part B Eng. 2013 46 221 226 10.1016/j.compositesb.2012.09.027 · DOI
- [30]Kerkeb L. Krämer U. The role of free histidine in xylem loading of nickel in Alyssum lesbiacum and Brassica juncea Plant Physiol. 2003 131 716 724 10.1104/pp102.010686 12586895 PMC166847 · DOI
- [31]Rai P.K. Lee S.S. Zhang M. Tsang Y.F. Kim K.-H. Heavy metals in food crops: Health risks, fate, mechanisms, and management Environ. Int. 2019 125 365 385 10.1016/j.envint.2019.01.067 30743144 · DOI
- [32]Udawat P. Singh J. Phytoremediation: A way towards sustainable Agriculture Int. J. Environ. Agric. Biotechnol. 2020 5 1167 1173 10.22161/ijeab.54.37 · DOI
- [33]Rascio N. Navari-Izzo F. Heavy metal hyperaccumulating plants: How and why do they do it? And what makes them so interesting? Plant Sci. 2011 180 169 181 10.1016/j.plantsci.2010.08.016 21421358 · DOI · Paper page
- [34]van der Ent A. Baker A.J.M. Reeves R.D. Pollard A.J. Schat H. Hyperaccumulators of metal and metalloid trace elements: Facts and fiction Plant Soil 2013 362 319 334 10.1007/s11104-012-1287-3 · DOI
- [35]Angelova V. Ivanova R. Delibaltova V. Ivanov K. Bio-accumulation and distribution of heavy metals in fibre crops (flax, cotton and hemp) Ind. Crops Prod. 2004 19 197 205 10.1016/j.indcrop.2003.10.001 · DOI · Paper page
- [38]Raimondi G. Rodrigues J. Maucieri C. Borin M. Bona S. Phytomanagement of chromium-contaminated soils using Cannabis sativa (L.) Agronomy 2020 10 1223 10.3390/agronomy10091223 · DOI
- [39]Shi G. Cai Q. Zinc tolerance and accumulation in eight oil crops J. Plant Nutr. 2010 33 982 997 10.1080/01904161003728669 · DOI
- [41]Liu Z. Tran K.Q. A review on disposal and utilization of phytoremediation plants containing heavy metals Ecotoxicol. Environ. Saf. 2021 226 112821 10.1016/j.ecoenv.2021.112821 34571420 · DOI · Paper page
- [42]Chalot M. Blaudez D. Rogaume Y. Provent A.-S. Pascual C. Fate of trace elements during the combustion of phytoremediation wood Environ. Sci. Technol. 2012 46 13361 13369 10.1021/es3017478 23153074 · DOI · Paper page
- [43]Keller C. Ludwig C. Davoli F. Wochele J. Thermal treatment of metal-enriched biomass produced from heavy metal phytoextraction Environ. Sci. Technol. 2005 39 3359 3367 10.1021/es0484101 15926590 · DOI
- [44]McGrath S.P. Zhao J. Lombi E. Phytoremediation of metals, metalloids, and radionuclides Adv. Agron. 2002 75 1 56 10.1016/s0065-2113(02)75002-5 · DOI · Paper page
- [45]Sheoran V. Sheoran A.S. Poonia P. Phytomining of gold: A review J. Geochem. Explor. 2013 128 42 50 10.1016/j.gexplo.2013.01.008 · DOI
- [46]Andersson-Sköld Y. Hagelqvist A. Crutu G. Blom S. Bioenergy grown on contaminated land—A sustainable bioenergy contributor? Biofuels 2014 5 487 498 10.1080/17597269.2014.996728 · DOI
- [47]Huang H. Yao W. Li R. Ali A. Du J. Guo D. Xiao R. Guo Z. Zhang Z. Awasthi M.K. Effect of pyrolysis temperature on chemical form, behavior and environmental risk of Zn, Pb and Cd in biochar produced from phytoremediation residue Bioresour. Technol. 2018 249 487 493 10.1016/j.biortech.2017.10.020 29073559 · DOI
- [48]Schreurs E. Voets T. Thewys T. GIS-based assessment of the biomass potential from phytoremediation of contaminated agricultural land in the Campine region in Belgium Biomass Bioenergy 2011 35 4469 4480 10.1016/j.biombioe.2011.09.005 · DOI
- [50]Baker A.J.M. Accumulators and excluders-strategies in the response of plants to heavy metals J. Plant Nutr. 1981 3 643 654 10.1080/01904168109362867 · DOI · Paper page
- [51]Ghosh M. Singh S.P. A review on phytoremediation of heavy metals and utilization of its byproducts Appl. Ecol. Environ. Res. 2005 3 1 18 10.15666/aeer/0301_001018 · DOI
- [52]Ahmad R. Tehsin Z. Malik S.T. Asad S.A. Shahzad M. Bilal M. Shah M.M. Khan S.A. Phytoremediation potential of hemp (Cannabis sativa L.): Identification and characterization of heavy metals responsive genes: Biotechnology CLEAN Soil Air Water 2016 44 195 201 10.1002/clen.201500117 · DOI · Paper page
- [53]Linger P. Müssig J. Fischer H. Kobert J. Industrial hemp (Cannabis sativa L.) growing on heavy metal contaminated soil: Fibre quality and phytoremediation potential Ind. Crop. Prod. 2002 16 33 42 10.1016/S0926-6690(02)00005-5 · DOI · Paper page
- [54]Shi G. Liu C. Cui M. Ma Y. Cai Q. Cadmium tolerance and bioaccumulation of 18 hemp accessions Appl. Biochem. Biotechnol. 2012 168 163 173 10.1007/s12010-011-9382-0 21938417 · DOI
- [55]Vandenhove H. Van Hees M. Fibre crops as alternative land use for radioactively contaminated arable land J. Environ. Radioact. 2005 81 131 141 10.1016/j.jenvrad.2005.01.002 15795030 · DOI · Paper page
- [58]Morin-Crini N. Staelens J.N. Loiacono S. Martel B. Chanet G. Crini G. Simultaneous removal of Cd, Co, Cu, Mn, Ni, and Zn from synthetic solutions on a hemp-based felt. III. Real discharge waters J. Appl. Polym. Sci. 2019 137 48823 10.1002/app.48823 · DOI
- [61]Shanker A. Cervantes C. Lozatavera H. Avudainayagam S. Chromium toxicity in plants Environ. Int. 2005 31 739 753 10.1016/j.envint.2005.02.003 15878200 · DOI
- [62]Caldelas C. Bort J. Febrero A. Ultrastructure and subcellular distribution of Cr in Iris pseudacorus L. using TEM and X-ray microanalysis Cell Biol. Toxicol. 2012 28 57 68 10.1007/s10565-011-9205-7 22009188 · DOI
- [64]Arru L. Rognoni S. Baroncini M. Bonatti P.M. Perata P. Copper localization in Cannabis sativa L. grown in a copper-rich solution Euphytica 2004 140 33 38 10.1007/s10681-004-4752-0 · DOI
- [65]Bona E. Marsano F. Cavaletto M. Berta G. Proteomic characterization of copper stress response in Cannabis sativa roots Proteomics 2007 7 1121 1130 10.1002/pmic.200600712 17352425 · DOI
- [66]Elisa B. Marsano F. Cavaletto M. Berta G. Copper stress in Cannabis sativa roots: Morphological and pro-teomic analysis Caryologia 2007 60 96 101 10.1080/00087114.2007.10589553 · DOI
- [67]Zhang D. Tai L.K. Wong L.L. Chiu L.-L. Sethi S.K. Koay E.S.C. Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer Mol. Cell. Proteom. 2005 4 1686 1696 10.1074/mcp.M400221-MCP200 16048908 · DOI
- [68]Gao S. Wang B. Xie S. Xu X. Zhang J. Pei L. Yu Y. Yang W. Zhang Y. A high-quality reference genome of wild Cannabis sativa Hortic. Res. 2020 7 73 10.1038/s41438-020-0295-3 32377363 PMC7195422 · DOI
- [70]Shim D. Kim S. Choi Y.-I. Song W.-Y. Park J. Youk E.S. Jeong S.-C. Martinoia E. Noh E.-W. Lee Y. Transgenic poplar trees expressing yeast cadmium factor 1 exhibit the characteristics necessary for the phytoremediation of mine tailing soil Chemosphere 2013 90 1478 1486 10.1016/j.chemosphere.2012.09.044 23062827 · DOI
- [71]Yan A. Wang Y. Tan S.N. Mohd Yusof M.L. Ghosh S. Chen Z. Phytoremediation: A promising approach for revegetation of heavy metal-polluted land Front. Plant Sci. 2020 11 359 10.3389/fpls.2020.00359 32425957 PMC7203417 · DOI · Paper page
- [72]Koźmińska A. Wiszniewska A. Hanus-Fajerska E. Muszyńska E. Recent strategies of increasing metal tolerance and phytoremediation potential using genetic transformation of plants Plant Biotechnol. Rep. 2018 12 1 14 10.1007/s11816-017-0467-2 29503668 PMC5829118 · DOI
- [73]Das N. Bhattacharya S. Maiti M.K. Enhanced cadmium accumulation and tolerance in transgenic tobacco overexpressing rice metal tolerance protein gene OsMTP1 is promising for phytoremediation Plant Physiol. Biochem. 2016 105 297 309 10.1016/j.plaphy.2016.04.049 27214086 · DOI
- [74]Mani D. Kumar C. Biotechnological advances in bioremediation of heavy metals contaminated ecosystems: An overview with special reference to phytoremediation Int. J. Environ. Sci. Technol. 2014 11 843 872 10.1007/s13762-013-0299-8 · DOI
- [75]Wu G. Kang H. Zhang X. Shao H. Chu L. Ruan C. A critical review on the bio-removal of hazardous heavy metals from contaminated soils: Issues, progress, eco-environmental concerns and opportunities J. Hazard. Mater. 2010 174 1 8 10.1016/j.jhazmat.2009.09.113 19864055 · DOI
- [76]Dolgin E. Inner Workings: Genomics blazes a trail to improved cannabis cultivation Proc. Natl. Acad. Sci. USA 2019 116 8638 8640 10.1073/pnas.1904094116 31040257 PMC6500169 · DOI
- [77]Schluttenhofer C. Yuan L. Challenges towards revitalizing hemp: A multifaceted crop Trends Plant Sci. 2017 22 917 929 10.1016/j.tplants.2017.08.004 28886910 · DOI · Paper page
- [78]Kodym A. Afza R. Physical and chemical mutagenesis Plant Functional Genomics Humana Press Totowa, NJ, USA 2003 Volume 236 189 204 14501066
- [79]Oladosu Y. Rafii M.Y. Abdullah N. Hussin G. Ramli A. Rahim H.A. Miah G. Usman M. Principle and application of plant mutagenesis in crop improvement: A review Biotechnol. Biotechnol. Equip. 2016 30 1 16 10.1080/13102818.2015.1087333 · DOI
- [80]Koornneeff M. Dellaert L.W.M. van der Veen J.H. EMS- and relation-induced mutation frequencies at individual loci in Arabidopsis thaliana (L.) Heynh Mutat. Res. Fundam. Mol. Mech. Mutagenesis 1982 93 109 123 10.1016/0027-5107(82)90129-4 7062928 · DOI
- [81]Westergaard M. Chemical mutagenesis in relation to the concept of the gene Experientia 1957 13 224 234 10.1007/BF02157427 13447934 · DOI
- [82]Kumawat S. Rana N. Bansal R. Vishwakarma G. Mehetre S.T. Das B.K. Kumar M. Yadav S.K. Sonah H. Sharma T.R. Expanding avenue of fast neutron mediated mutagenesis for crop improvement Plants 2019 8 164 10.3390/plants8060164 PMC6631465 31185678 · DOI
- [83]Li X. Song Y. Century K. Straight S. Ronald P. Dong X. Lassner M. Zhang Y. A fast neutron deletion mutagenesis-based reverse genetics system for plants: Fast neutron deletion mutagenesis-based reverse genetics Plant J. 2001 27 235 242 10.1046/j.1365-313x.2001.01084.x 11532169 · DOI
- [84]Sikora P. Chawade A. Larsson M. Olsson J. Olsson O. Mutagenesis as a tool in plant genetics, functional genomics, and breeding Int. J. Plant Genom. 2011 2011 1 13 10.1155/2011/314829 PMC3270407 22315587 · DOI
- [85]Wu J.-L. Wu C. Lei C. Baraoidan M. Bordeos A. Madamba M.R.S. Ramos-Pamplona M. Mauleon R. Portugal A. Ulat V.J. Chemical- and irradiation-induced mutants of indica rice IR64 for forward and reverse genetics Plant Mol. Biol. 2005 59 85 97 10.1007/s11103-004-5112-0 16217604 · DOI
- [86]Henry I.M. Nagalakshmi U. Lieberman M.C. Ngo K.J. Krasileva K.V. Vasquez-Gross H. Akhunova A. Akhunov E. Dubcovsky J. Tai T.H. Efficient genome-wide detection and cataloging of EMS-induced mutations using exome capture and next-generation sequencing Plant Cell 2014 26 1382 1397 10.1105/tpc.113.121590 24728647 PMC4036560 · DOI
- [87]Hilioti Z. Ganopoulos I. Ajith S. Bossis I. Tsaftaris A. A novel arrangement of zinc finger nuclease system for in vivo targeted genome engineering: The tomato LEC1-LIKE4 gene case Plant Cell Rep. 2016 35 2241 2255 10.1007/s00299-016-2031-x 27473525 · DOI
- [88]Holme I.B. Wendt T. Holm P.B. Intragenesis and cisgenesis as alternatives to transgenic crop development Plant Biotechnol. J. 2013 11 395 407 10.1111/pbi.12055 23421562 · DOI
- [89]Malzahn A. Lowder L. Qi Y. Plant genome editing with TALEN and CRISPR Cell Biosci. 2017 7 21 10.1186/s13578-017-0148-4 28451378 PMC5404292 · DOI
- [90]Sprink T. Metje J. Hartung F. Plant genome editing by novel tools: TALEN and other sequence specific nucleases Curr. Opin. Biotechnol. 2015 32 47 53 10.1016/j.copbio.2014.11.010 25448232 · DOI
- [91]Mishra R. Joshi R.K. Zhao K. Base editing in crops: Current advances, limitations and future implications Plant Biotechnol. J. 2020 18 20 31 10.1111/pbi.13225 31365173 PMC6920333 · DOI
- [92]Monsur M.B. Shao G. Lv Y. Ahmad S. Wei X. Hu P. Tang S. Base editing: The ever expanding clustered regularly interspaced short palindromic repeats (CRISPR) tool kit for precise genome editing in plants Genes 2020 11 466 10.3390/genes11040466 32344599 PMC7231171 · DOI
- [93]Hou H. Atlihan N. Lu Z.-X. New biotechnology enhances the application of cisgenesis in plant breeding Front. Plant Sci. 2014 5 389 10.3389/fpls.2014.00389 25157261 PMC4127943 · DOI
- [94]Chandra S. Lata H. ElSohly M.A. Cannabis sativa L.—Botany and Biotechnology Springer Berlin/Heidelberg, Germany 2017 1 474
- [97]Wahby I. Caba J.M. Ligero F. Agrobacterium infection of hemp (Cannabis sativa L.): Establishment of hairy root cultures J. Plant Interact. 2013 8 312 320 10.1080/17429145.2012.746399 · DOI · Paper page
Cited by
Sorted by citations
Moving towards Biofuels and High-Value Products through Phytoremediation and Biocatalytic Processes
Ionata, E., Caputo, E., Mandrich, L., & Marcolongo, L. (2024) · Catalysts · doi:10.3390/catal14020118 · Cited by 34 · see citing works
Basak, M., Broadway, M., Lewis, J., Starkey, H., Bloomquist, M., Peszlen, I., Davis, J., Lucia, L. A., & Pal, L. (2025) · BioResources · doi:10.15376/biores.20.2.basak · Cited by 22 · see citing works
“Near the Chernobyl Nuclear Disaster site, hemp was grown in 1986 to aid in the decontamination of the soil (Adesina et al. 2020; Ahmad et al. 2016; Citterio et al. 2003; Placido and Lee 2022).”
InfluentialBiochemical Changes Induced by the Administration of Cannabis sativa Seeds in Diabetic Wistar Rats
Munteanu, C., Mihai, M., Dulf, F., Ona, A., Muntean, L., Ranga, F., Urdă, C., Pop, D., Mihaiescu, T., Mârza, S. M., et al. (2023) · Nutrients · doi:10.3390/nu15132944 · Cited by 7 · see citing works
- Authors
- Placido, D. F., & Lee, C. C.
- Affiliations
- Agricultural Research Service (US)
- Corresponding author
- Lee, Charles C.
- ORCID
- Lee, Charles C.
- Venue
- Plants
- Publisher
- MDPI AG
- Published
- 2022-02-23
- Volume
- 11
- Issue
- 5
- Pages
- 595
- ISSN
- 2223-7747 (ISSN-L)
- PMC
- PMC8912475
- OpenAlex
- W4213431040
- Cited by
- 96
- References
- 9
- Citations by year
- 2026: 21 · 2025: 23 · 2024: 21 · 2023: 22 · 2022: 9
- FWCI
- 1.07
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Plants (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Physical Sciences › Environmental Science › Pollution › Heavy metals in environment
- Physical Sciences › Environmental Science › Water Science and Technology › Heavy Metal Pollution Remediation
- Physical Sciences › Chemistry › Analytical Chemistry › Heavy Metals in Plants
- Keywords
- industrial hemp, Cannabis sativa, phytoremediation, heavy metals, soil contamination, metal accumulation, metal tolerance, bioengineering, genome annotation, biomass utilization
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review