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Cited by 287

The DOI matches its Crossref record; 138 of the 138 references it cites were found in a registry or an index.

Poly(Vinyl Alcohol)-Based Nanofibrous Electrospun Scaffolds for Tissue Engineering Applications

Open access
Teixeira, Marta A., Amorim, M. Teresa P., Felgueiras, Helena P.·2019·Polymers

Abstract

Tissue engineering (TE) holds an enormous potential to develop functional scaffolds resembling the structural organization of native tissues, to improve or replace biological functions and prevent organ transplantation. Amongst the many scaffolding techniques, electrospinning has gained widespread interest because of its outstanding features that enable the production of non-woven fibrous structures with a dimensional organization similar to the extracellular matrix. Various polymers can be electrospun in the form of three-dimensional scaffolds. However, very few are successfully processed using environmentally friendly solvents; poly(vinyl alcohol) (PVA) is one of those. PVA has been investigated for TE scaffolding production due to its excellent biocompatibility, biodegradability, chemo-thermal stability, mechanical performance and, most importantly, because of its ability to be dissolved in aqueous solutions. Here, a complete overview of the applications and recent advances in PVA-based electrospun nanofibrous scaffolds fabrication is provided. The most important achievements in bone, cartilage, skin, vascular, neural and corneal biomedicine, using PVA as a base substrate, are highlighted. Additionally, general concepts concerning the electrospinning technique, the stability of PVA when processed, and crosslinking alternatives to glutaraldehyde are as well reviewed.

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Crossref · 10.3390/polym12010007

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Metadata

Authors
Teixeira, M. A., Amorim, M. T. P., & Felgueiras, H. P.
Venue
Polymers
Publisher
MDPI AG
Published
2019-12-18
Volume
12
Issue
1
Pages
7
ISSN
2073-4360 (ISSN-L)
OpenAlex
W2995699906
Cited by
287
References
138
FWCI
6.26
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Poly(Vinyl Alcohol)-Based Nanofibrous Electrospun Scaffolds for Tissue Engineering Applications. https://app.cochat.ai/papers/10.3390/polym12010007
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Teixeira, M. A., Amorim, M. T. P., & Felgueiras, H. P. (2019). Poly(Vinyl Alcohol)-Based Nanofibrous Electrospun Scaffolds for Tissue Engineering Applications. Polymers. https://doi.org/10.3390/polym12010007

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