The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Carotenoids: potential allies of cardiovascular health?
Open accessAbstract
Carotenoids are a class of natural, fat-soluble pigments found principally in plants. They have potential antioxidant biological properties because of their chemical structure and interaction with biological membranes. Epidemiologic studies supported the hypothesis that antioxidants could be used as an inexpensive means of both primary and secondary cardiovascular disease (CVD) prevention. In fact, the oxidation of low-density lipoproteins (LDL) in the vessels plays a key role in the development of atherosclerotic lesions. The resistance of LDL to oxidation is increased by high dietary antioxidant intake, so that carotenoids, as part of food patterns such as the Mediterranean diet, may have beneficial effects on cardiovascular health too. Further properties of carotenoids leading to a potential reduction of cardiovascular risk are represented by lowering of blood pressure, reduction of pro-inflammatory cytokines and markers of inflammation (such as C-reactive protein), and improvement of insulin sensitivity in muscle, liver, and adipose tissues. In addition, recent nutrigenomics studies have focused on the exceptional ability of carotenoids in modulating the expression of specific genes involved in cell metabolism. The aim of this review is to focus attention to this effect of some carotenoids to prevent CVD.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Inflammation in atherosclerosis
Libby, P. (2002) · Nature · doi:10.1038/nature01323 · Cited by 8,315
Inflammation and insulin resistance
Shoelson, S. E. (2006) · Journal of Clinical Investigation · doi:10.1172/jci29069 · Cited by 4,769
(1994) · New England Journal of Medicine · doi:10.1056/nejm199404143301501 · Cited by 4,737
Neaton, J. D. (1992) · Archives of Internal Medicine · doi:10.1001/archinte.1992.00400130082009 · Cited by 784
Lycopene: A Biologically Important Carotenoid for Humans?
Stahl, W., & Sies, H. (1996) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1996.0525 · Cited by 712 · cited 1×
“In fact, it is a lipophilic molecule transported in blood by lipoproteins which accumulates in human tissues, also in the vasculature (66).”
BackgroundPotential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae
Yuan, J., Peng, J., Yin, K., & Wang, J. (2011) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201000414 · Cited by 649
Fruits and Vegetables That Are Sources for Lutein and Zeaxanthin: The Macular Pigment in Human Eyes
Sommerburg, O., Keunen, J. E. E., Bird, A. C., & van Kuijk, F. J. G. M. (1998) · British Journal of Ophthalmology · doi:10.1136/bjo.82.8.907 · Cited by 527
Heilbronn, L. K., Noakes, M., & Clifton, P. M. (2001) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.21.6.968 · Cited by 331
Retinoic Acid Blocks Adipogenesis by Inhibiting C/EBPβ-Mediated Transcription
Schwarz, E. J., Reginato, M. J., Shao, D., Krakow, S. L., & Lazar, M. A. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.3.1552 · Cited by 302
Yoshida, H., Yanai, H., Ito, K., Tomono, Y., Koikeda, T., Tsukahara, H., & Tada, N. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.10.012 · Cited by 269
Mieszczanska, H., Pietrasik, G., Piotrowicz, K., McNitt, S., Moss, A. J., & Zareba, W. (2008) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2007.07.077 · Cited by 56
Denniss, S. G. (2008) · Vascular Health and Risk Management · doi:10.2147/vhrm.2008.04.01.213 · Cited by 37 · cited 1×
“These results suggest the beneficial effect of higher serum and tissue levels of lycopene: for this reason dietary intake of lycopene (especially if diet is also rich in extra-virgin olive oil) (74) or lycopene supplementation (75) seems to decrease the risk of CVD (62, 76).”
Background
Cited by
Microalgae: A potential alternative to health supplementation for humans
Koyande, A. K., Chew, K. W., Rambabu, K., Tao, Y., Chu, D.-T., & Show, P.-L. (2019) · Food Science and Human Wellness · doi:10.1016/j.fshw.2019.03.001 · Cited by 908
Carotenoids: biochemistry, pharmacology and treatment
Milani, A., Basirnejad, M., Shahbazi, S., & Bolhassani, A. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13625 · Cited by 781
Omega-3 Polyunsaturated Fatty Acids: Benefits and Endpoints in Sport
Gammone, M. A., Riccioni, G., Parrinello, G., & D’Orazio, N. (2018) · Nutrients · doi:10.3390/nu11010046 · Cited by 326
Self-citationBanwo, K., Olojede, A. O., Adesulu-Dahunsi, A. T., Verma, D. K., Thakur, M., Tripathy, S., Singh, S., Patel, A. R., Gupta, A. K., Aguilar, C. N., et al. (2021) · Food Bioscience · doi:10.1016/j.fbio.2021.101320 · Cited by 313
Concepts and studies on lipid and pigments of microalgae: A review
D’Alessandro, E. B., & Antoniosi Filho, N. R. (2016) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2015.12.162 · Cited by 289
Metadata
- Authors
- Maria, A. G., Graziano, R., & Nicolantonio, D.
- Venue
- Food & Nutrition Research
- Publisher
- SNF Swedish Nutrition Foundation
- Published
- 2015-01
- Volume
- 59
- Issue
- 1
- Pages
- 26762
- ISSN
- 1654-661X (ISSN-L)
- 1654-6628
- OpenAlex
- W2072970826
- Cited by
- 323
- References
- 12
- FWCI
- 15.68
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
