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Neuromodulatory effects and targets of the SCFAs and gasotransmitters produced by the human symbiotic microbiota
Open accessAbstract
The symbiotic gut microbiota plays an important role in the development and homeostasis of the host organism. Its physiological, biochemical, behavioral, and communicative effects are mediated by multiple low molecular weight compounds. Recent data on small molecules produced by gut microbiota in mammalian organisms demonstrate the paramount importance of these biologically active molecules in terms of biology and medicine. Many of these molecules are pleiotropic mediators exerting effects on various tissues and organs. This review is focused on the functional roles of gaseous molecules that perform neuromediator and/or endocrine functions. The molecular mechanisms that underlie the effects of microbial fermentation-derived gaseous metabolites are not well understood. It is possible that these metabolites produce their effects via immunological, biochemical, and neuroendocrine mechanisms that involve endogenous and microbial modulators and transmitters; of considerable importance are also changes in epigenetic transcriptional factors, protein post-translational modification, lipid and mitochondrial metabolism, redox signaling, and ion channel/gap junction/transporter regulation. Recent findings have revealed that interactivity among such modulators/transmitters is a prerequisite for the ongoing dialog between microbial cells and host cells, including neurons. Using simple reliable methods for the detection and measurement of short-chain fatty acids (SCFAs) and small gaseous molecules in eukaryotic tissues and prokaryotic cells, selective inhibitors of enzymes that participate in their synthesis, as well as safe chemical and microbial donors of pleiotropic mediators and modulators of host intestinal microbial ecology, should enable us to apply these chemicals as novel therapeutics and medical research tools.
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“It was described that SCFAs may modulate the levels of neurotransmitters and neurotrophic factors.”
From The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication (2020) · cites this paper as [115]
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“Propionate and butyrate exert an influence on the intracellular potassium level, which implies the involvement of SCFAs in the operation of cell signaling systems (115).”
From The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication (2020) · cites this paper as [115]
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“Propionate and butyrate can influence the cell signaling system via modification of the intracellular potassium levels (104), and they regulate the expression levels of tryptophan 5-hydroxylase 1, involved in the synthesis of serotonin, and tyrosine hydroxylase, which is involved in the biosynthesis of dopamine, adrenaline, and noradrenaline (105).”
From The gut-brain axis: how microbiota and host inflammasome influence brain physiology and pathology (2020) · cites this paper as [104]
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“First of all, the microbiota composition of MS patients is different from the one of healthy individuals (104).”
From The gut-brain axis: how microbiota and host inflammasome influence brain physiology and pathology (2020) · cites this paper as [104]
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Citations
Cites
Hill (2014) · doi:10.1038/nrgastro.2014.66 · Cited by 9,592
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
Wang, R. (2012) · Physiological Reviews · doi:10.1152/physrev.00017.2011 · Cited by 1,962
Regulation of inflammation by short chain fatty acids
Vinolo, M. A. R., Rodrigues, H. G., Nachbar, R. T., & Curi, R. (2011) · Nutrients · doi:10.3390/nu3100858 · Cited by 1,724
Psychobiotics: A novel class of psychotropic
Dinan, T. G., Stanton, C., & Cryan, J. F. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.05.001 · Cited by 1,287
Minireview: Gut microbiota: The neglected endocrine organ
Clarke, G., Stilling, R. M., Kennedy, P. J., Stanton, C., Cryan, J. F., & Dinan, T. G. (2014) · Molecular Endocrinology · doi:10.1210/me.2014-1108 · Cited by 1,192
Hemarajata, P., & Versalovic, J. (2013) · Therapeutic Advances in Gastroenterology · doi:10.1177/1756283x12459294 · Cited by 1,083
The role of microbiome in central nervous system disorders
Wang, Y., & Kasper, L. H. (2014) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2013.12.015 · Cited by 803
H 2 S: A Universal Defense Against Antibiotics in Bacteria
Shatalin, K. Y., Shatalina, E., Mironov, A. S., & Nudler, E. (2011) · Science · doi:10.1126/science.1209855 · Cited by 769
Dietary Inorganic Nitrate Improves Mitochondrial Efficiency in Humans
Larsen, F. J., Schiffer, T. A., Borniquel, S., Sahlin, K., Ekblom, B., Lundberg, J. O., & Weitzberg, E. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.01.004 · Cited by 689
The Gut Microbiome and the Brain
Galland, L. (2014) · Journal of Medicinal Food · doi:10.1089/jmf.2014.7000 · Cited by 648
Research works printed but not linked: 2
- Oleskin, 2013, Biopolitical approach to rehabilitation: potential role of microbial neurochemistry, Regen Med J, N1, 60
- El Aidy, 2016, Microbial endocrinology: interkingdom signaling in infectious disease and health. Advances in experimental medicine and biology 874, 301
Cited by
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Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286
The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication
Silva, Y. P., Bernardi, A., & Frozza, R. L. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00025 · Cited by 3,043
“Propionate and butyrate exert an influence on the intracellular potassium level, which implies the involvement of SCFAs in the operation of cell signaling systems (115).”
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Strandwitz, P. (2018) · Brain Research · doi:10.1016/j.brainres.2018.03.015 · Cited by 1,527
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O’Riordan, K. J., Collins, M., Moloney, G. M., Knox, E. G., Aburto, M. R., Fülling, C., Morley, S. J., Clarke, G. A., Schellekens, H., & Cryan, J. F. (2022) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2022.111572 · Cited by 788
Bonfili, L., Cecarini, V., Berardi, S., Scarpona, S., Suchodolski, J. S., Nasuti, C., Fiorini, D., Boarelli, M. C., Rossi, G., & Eleuteri, A. M. (2017) · Scientific Reports · doi:10.1038/s41598-017-02587-2 · Cited by 453
The role of the microbiome for human health: From basic science to clinical applications
Mohajeri, M. H., Brummer, R. J. M., Rastall, R. A., Weersma, R. K., Harmsen, H. J. M., Faas, M., & Eggersdorfer, M. (2018) · European Journal of Nutrition · doi:10.1007/s00394-018-1703-4 · Cited by 440
Role of microbiota-derived short-chain fatty acids in nervous system disorders
Mirzaei, R., Bouzari, B., Hosseini‐Fard, S. R., Mazaheri, M., Ahmadyousefi, Y., Abdi, M., Jalalifar, S., Karimitabar, Z., Teimoori, A., Keyvani, H., et al. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111661 · Cited by 408
Shandilya, S., Kumar, S., Jha, N. K., Kesari, K. K., & Ruokolainen, J. (2021) · Journal of Advanced Research · doi:10.1016/j.jare.2021.09.005 · Cited by 310
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Skonieczna-Żydecka, K., Grochans, E., Maciejewska, D., Szkup, M., Schneider-Matyka, D., Jurczak, A., Łoniewski, I., Kaczmarczyk, M., Marlicz, W., Czerwińska-Rogowska, M., et al. (2018) · Nutrients · doi:10.3390/nu10121939 · Cited by 284
The gut microbiota–brain axis in neurological disorder
Ullah, H., Arbab, S., Tian, Y., Liu, C., Chen, Y., Li, Q., Khan, M. I. U., Hassan, I. U., & Li, K. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1225875 · Cited by 292
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Varesi, A., Pierella, E., Romeo, M., Piccini, G. B., Alfano, C., Bjørklund, G., Oppong, A., Ricevuti, G., Esposito, C., Chirumbolo, S., et al. (2022) · Nutrients · doi:10.3390/nu14030668 · Cited by 225
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Tran, S. M.-S., & Mohajeri, M. H. (2021) · Nutrients · doi:10.3390/nu13030732 · Cited by 213
Luca, M., Di Mauro, M., Di Mauro, M., & Luca, A. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/4730539 · Cited by 190
Iszatt, N., Janssen, S., Lenters, V. C., Dahl, C., Stigum, H., Knight, R. D., Mandal, S., Peddada, S., González, A., Midtvedt, T., et al. (2019) · Microbiome · doi:10.1186/s40168-019-0645-2 · Cited by 173
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Tse, J. K. Y. (2017) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.7b00176 · Cited by 175
Dash, S., Syed, Y. A., & Khan, M. R. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.880544 · Cited by 193
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Tomášová, L., Konopelski, P., & Ufnal, M. (2016) · Molecules · doi:10.3390/molecules21111558 · Cited by 161
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Ohara, T. E., & Hsiao, E. Y. (2025) · Nature Reviews Microbiology · doi:10.1038/s41579-024-01136-9 · Cited by 147
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Wu, S., Liu, X., Jiang, R., Yan, X., & Ling, Z. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.650047 · Cited by 150
Bonfili, L., Cecarini, V., Gogoi, O., Berardi, S., Scarpona, S., Angeletti, M., Rossi, G., & Eleuteri, A. M. (2019) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2019.11.004 · Cited by 140
Liu, Z., Li, L., Ma, S., Jin, Y., Zhang, H., Li, Y., Sair, A. T., Pan, J., Liu, X., Li, X., et al. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c04290 · Cited by 129
Mao, Q., Manservisi, F., Panzacchi, S., Mandrioli, D., Menghetti, I., Vornoli, A., Bua, L., Falcioni, L., Lesseur, C., Chen, J., et al. (2018) · Environmental Health · doi:10.1186/s12940-018-0394-x · Cited by 124
Dysbiosis of gut microbiota in Polish patients with ulcerative colitis: a pilot study
Zakerska‐Banaszak, O., Tomczak, H., Gabryel, M., Baturo, A., Wolko, Ł., Michalak, M., Malińska, N., Mańkowska‐Wierzbicka, D., Eder, P., Dobrowolska, A., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-81628-3 · Cited by 121
Probiotics and Psychobiotics: the Role of Microbial Neurochemicals
Oleskin, A. V., & Ba, S. (2019) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-019-09583-0 · Cited by 94
Self-citationBasiouni, S., Téllez‐Isaías, G., Latorre, J. D., Graham, D. B., Petrone-García, V. M., El-Seedi, H. R., Yalçın, S., El‐Wahab, A. A., Visscher, C., May‐Simera, H., et al. (2023) · Veterinary Sciences · doi:10.3390/vetsci10010055 · Cited by 106
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Holmes, M., Flaminio, Z., Vardhan, M., Xu, F., Li, X., Devinsky, O., & Saxena, D. B. (2020) · Epilepsia · doi:10.1111/epi.16744 · Cited by 76
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Hopper, C., Cruz, L. K. D. L., Lyles, K. V. M., Wareham, L. K., Gilbert, J. A., Eichenbaum, Z., Magierowski, M., Poole, R. K., Wollborn, J., & Wang, B. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00586 · Cited by 73
Shabbir, U., Tyagi, A., Elahi, F., Aloo, S. O., & Oh, D. (2021) · Antioxidants · doi:10.3390/antiox10091370 · Cited by 71
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Corriero, A., Gadaleta, R. M., Puntillo, F., Inchingolo, F., Moschetta, A., & Brienza, N. (2022) · Critical Care · doi:10.1186/s13054-022-04259-8 · Cited by 78
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Kodukula, K., Faller, D. V., Harpp, D. N., Kanara, I., Pernokas, J., Pernokas, M., Powers, W. R., Soukos, N. S., Steliou, K., & Moos, W. H. (2017) · BioResearch open access · doi:10.1089/biores.2017.0020 · Cited by 70
Lanza, M., Filippone, A., Ardizzone, A., Casili, G., Paterniti, I., Esposito, E., & Campolo, M. (2021) · Cells · doi:10.3390/cells10102756 · Cited by 69
Oleskin, A. V., Ba, S., & Rogovskii, V. (2017) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-017-9262-1 · Cited by 65
Self-citationExploring the microbiota-gut-brain axis: impact on brain structure and function
Yassin, L. K., Nakhal, M. M., Alderei, A., Almehairbi, A., Mydeen, A. B., Akour, A. A., & Hamad, M. I. K. (2025) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2025.1504065 · Cited by 64
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Rea, K., O’Mahony, S. M., Dinan, T. G., & Cryan, J. F. (2016) · Handbook of experimental pharmacology · doi:10.1007/164_2016_115 · Cited by 64
A brief history of carbon monoxide and its therapeutic origins
Hopper, C., Zambrana, P. N., Goebel, U., & Wollborn, J. (2021) · Nitric Oxide · doi:10.1016/j.niox.2021.04.001 · Cited by 59
Qiao, C.-M., Huang, W., Zhou, Y., Quan, W., Niu, G.-Y., Li, T., Zhang, M.-X., Wu, J., Zhao, L., Zhao, W.-J., et al. (2024) · Brain Sciences · doi:10.3390/brainsci14030238 · Cited by 62
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Zhang, Z., Zhang, Y., Li, J., Fu, C., & Zhang, X. (2021) · Molecules · doi:10.3390/molecules26123692 · Cited by 55
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Lanza, M., Filippone, A., Casili, G., Giuffrè, L., Scuderi, S. A., Paterniti, I., Campolo, M., Cuzzocrea, S., & Esposito, E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23094847 · Cited by 35
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Proano, A. C., Viteri, J. A., Orozco, E. N., Prado, M. A. C., Costa, S. C., Reyes, D., German-Montenegro, M., Moncayo, D. F., Tobar, A. C., & Moncayo, J. A. (2023) · Neurology International · doi:10.3390/neurolint15020047 · Cited by 28
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Ugwu, O. P.-C., Okon, M. B., Alum, E. U., Ugwu, C. N., Anyanwu, G. E., Basajja, M., Ogenyi, F. C., Eze, V. H. U., Anyanwu, C. N., Ezeonwumelu, J. O. C., et al. (2025) · Medicine · doi:10.1097/md.0000000000043542 · Cited by 29
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Sugihartono, T., Fauzia, K. A., Miftahussurur, M., Waskito, L. A., Rejeki, P. S., I’tishom, R., Alfaray, R. I., Doohan, D., Amalia, R., Savitri, C. M. A., et al. (2022) · Gut Pathogens · doi:10.1186/s13099-022-00510-3 · Cited by 21
Bendriss, G., MacDonald, R. S., & McVeigh, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241511978 · Cited by 25
Welcome, M. O. (2018) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000492491 · Cited by 22
Missiego-Beltrán, J., Olalla-Álvarez, E. M., González-Brugera, A., & Beltrán-Velasco, A. I. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25168998 · Cited by 19
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Marsiglia, R., Marangelo, C., Vernocchi, P., Scanu, M., Pane, S., Russo, A., Guanziroli, E., CHIERICO, F. D., Valeriani, M., Molteni, F., et al. (2023) · Microorganisms · doi:10.3390/microorganisms12010037 · Cited by 19
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Metadata
- Authors
- Oleskin, A. V., & Shenderov, B. A.
- Affiliations
- Lomonosov Moscow State University (RU)
- Venue
- Microbial Ecology in Health & Disease
- Publisher
- Co-Action Publishing
- Published
- 2016-07-05
- Volume
- 27
- Issue
- 0
- Pages
- 30971-30971
- ISSN
- 0891-060X (ISSN-L)
- 1651-2235
- PMC
- PMC4937721
- OpenAlex
- W2472180307
- Cited by
- 145
- References
- 88
- Citations by year
- 2026: 3 · 2025: 16 · 2024: 14 · 2023: 15 · 2022: 28 · 2021: 25 · 2020: 12 · 2019: 10 · 2018: 12 · 2017: 8 · 2016: 2
- FWCI
- 5.55
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- cc-by-nc
- Locations
- Microbial Ecology in Health and Disease (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Keywords
- short-chain fatty acids, gasotransmitters, gut microbiota, neuromodulation, neuroendocrine signaling, microbial metabolites, host-microbe interactions, microbial fermentation, redox signaling, ion channel modulation, epigenetic regulation, post-translational modification, gut-brain axis, therapeutic target
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