Cited by 3,001Gut microbiota and healthInfant Nutrition and HealthOral microbiology and periodontitis research

The DOI matches its Crossref record; 163 of the 163 references it cites were found in a registry or an index.

Role of the normal gut microbiota

Open access

Jandhyala, Sai Manasa·2015·World Journal of Gastroenterology

DOI 10.3748/wjg.v21.i29.8787PMC PMC4528021

Open this paper in CoChat — free account Open PDF

Abstract

Relation between the gut microbiota and human health is being increasingly recognised. It is now well established that a healthy gut flora is largely responsible for overall health of the host. The normal human gut microbiota comprises of two major phyla, namely Bacteroidetes and Firmicutes. Though the gut microbiota in an infant appears haphazard, it starts resembling the adult flora by the age of 3 years. Nevertheless, there exist temporal and spatial variations in the microbial distribution from esophagus to the rectum all along the individual's life span. Developments in genome sequencing technologies and bioinformatics have now enabled scientists to study these microorganisms and their function and microbe-host interactions in an elaborate manner both in health and disease. The normal gut microbiota imparts specific function in host nutrient metabolism, xenobiotic and drug metabolism, maintenance of structural integrity of the gut mucosal barrier, immunomodulation, and protection against pathogens. Several factors play a role in shaping the normal gut microbiota. They include (1) the mode of delivery (vaginal or caesarean); (2) diet during infancy (breast milk or formula feeds) and adulthood (vegan based or meat based); and (3) use of antibiotics or antibiotic like molecules that are derived from the environment or the gut commensal community. A major concern of antibiotic use is the long-term alteration of the normal healthy gut microbiota and horizontal transfer of resistance genes that could result in reservoir of organisms with a multidrug resistant gene pool.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.3748/wjg.v21.i29.8787

Cites

163 of 163 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Structure, function and diversity of the healthy human microbiome
The Human Microbiome Project Consortium (2012) · Nature · doi:10.1038/nature11234 · Cited by 11,726
A human gut microbial gene catalogue established by metagenomic sequencing
MetaHIT Consortium, Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., et al. (2010) · Nature · doi:10.1038/nature08821 · Cited by 11,624
Diet rapidly and reproducibly alters the human gut microbiome
David, L. A., Maurice, C. F., Carmody, R. N., Gootenberg, D. B., Button, J. E., Wolfe, B. E., Ling, A. V., Devlin, A. S., Varma, Y., Fischbach, M. A., et al. (2014) · Nature · doi:10.1038/nature12820 · Cited by 10,100
Pattern Recognition Receptors and Inflammation
Takeuchi, O., & Akira, S. (2010) · Cell · doi:10.1016/j.cell.2010.01.022 · Cited by 8,895
Human gut microbes associated with obesity
Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006) · Nature · doi:10.1038/4441022a · Cited by 8,785
Human gut microbiome viewed across age and geography
Yatsunenko, T., Rey, F. E., Manary, M. J., Trehan, I., Dominguez-Bello, M. G., Contreras, M., Magris, M., Hidalgo, G., Baldassano, R. N., Anokhin, A. P., et al. (2012) · Nature · doi:10.1038/nature11053 · Cited by 7,815
Enterotypes of the human gut microbiome
MetaHIT Consortium (additional members), Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., et al. (2011) · Nature · doi:10.1038/nature09944 · Cited by 7,548
Changes of Intestinal Functions in Liver Cirrhosis
Fukui, H., & Wiest, R. (2016) · Inflammatory Intestinal Diseases · doi:10.1159/000444436 · Cited by 6,820
Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
De Filippo, C., Cavalieri, D., Di Paola, M., Ramazzotti, M., Poullet, J. B., Massart, S., Collini, S., Pieraccini, G., & Lionetti, P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005963107 · Cited by 5,579
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
Furusawa, Y., Obata, Y., Fukuda, S., Endo, T. A., Nakato, G., Takahashi, D., Nakanishi, Y., Uetake, C., Kato, K., Kato, T., et al. (2013) · Nature · doi:10.1038/nature12721 · Cited by 5,549

Flagged first, then by citations

Show all 163 references

Research works printed but not linked: 2

Bourriaud C, Akoka S, Goupry S, Robins R, Cherbut C, Michel C. Butyrate production from lactate by human colonic microflora. Reprod Nutr Dev 2002;42:S55.
10.1016/j.immuni.2012 · DOI

Sorted by citations

Items 901–1,000 of 1,002

Gastrointestinal Tract, Microbiota and Multiple Sclerosis (MS) and the Link Between Gut Microbiota and CNS
Yousefi, B., Babaeizad, A., Banihashemian, S. Z., Feyzabadi, Z. K., Dadashpour, M., Pahlevan, D., Ghaffari, H., & Eslami, M. (2022) · Current Microbiology · doi:10.1007/s00284-022-03150-7 · Cited by 29
Accumulation of Black Carbon Particles in Placenta, Cord Blood, and Childhood Urine in Association with the Intestinal Microbiome Diversity and Composition in Four- to Six-Year-Old Children in the ENVIR ON AGE Birth Cohort
Pee, T. V., Hogervorst, J. G. F., Dockx, Y., Witters, K., Thijs, S., Wang, C., Bongaerts, E., Hamme, J. D. V., Vangronsveld, J., Ameloot, M. M., et al. (2023) · Environmental Health Perspectives · doi:10.1289/ehp11257 · Cited by 28
Influence of Bifidobacterium breve on the Glycaemic Control, Lipid Profile and Microbiome of Type 2 Diabetic Subjects: A Preliminary Randomized Clinical Trial
Chaiyasut, C., Sivamaruthi, B. S., Lailerd, N., Sirilun, S., Thangaleela, S., Khongtan, S., Bharathi, M., Kesika, P., Saelee, M., Choeisoongnern, T., et al. (2023) · Pharmaceuticals · doi:10.3390/ph16050695 · Cited by 30
Dissecting the role of the gut microbiome and fecal microbiota transplantation in radio- and immunotherapy treatment of colorectal cancer
Dingenen, L. V., Segers, C., Wouters, S., Mysara, M., Leys, N., Kumar‐Singh, S., Malhotra‐Kumar, S., & Houdt, R. V. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1298264 · Cited by 29
Gut microbiome and plasma metabolome alterations in myopic mice
Li, H., Liu, S., Zhang, K., Zhu, X., Dai, J., & Lü, Y. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1251243 · Cited by 26
Quantitation of circulating short-chain fatty acids in small volume blood samples from animals and humans
Fristedt, R., Ruppert, V., Trower, T. M., Cooney, J. M., & Landberg, R. (2024) · Talanta · doi:10.1016/j.talanta.2024.125743 · Cited by 29
Effects of intake of Lactobacillus casei subsp. casei 327 on skin conditions: a randomized, double-blind, placebo-controlled, parallel-group study in women
Saito, Y., Mihara, T., MARUYAMA, K., Saito, J., IKEDA, M., Tomonaga, A., & Kumagai, T. (2017) · Bioscience of Microbiota Food and Health · doi:10.12938/bmfh.16-031 · Cited by 27
PLGA-encapsulated CpG ODN and Campylobacter jejuni lysate modulate cecal microbiota composition in broiler chickens experimentally challenged with C. jejuni
Taha-Abdelaziz, K., Yitbarek, A., Alkie, T. N., Hodgins, D. C., Read, L. R., Weese, J. S., & Sharif, S. (2018) · Scientific Reports · doi:10.1038/s41598-018-30510-w · Cited by 28
Microbiome study of initial gut microbiota from newborn infants to children reveals that diet determines its compositional development
Ku, H.-J., Kim, Y.-T., & Lee, J.-H. (2020) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2002.02042 · Cited by 26
The protective effect of Schisandra chinensis (Turcz.) Baill. polysaccharide on DSS ‐induced ulcerative colitis in mice via the modulation of gut microbiota and inhibition of NF‐κB activation
Guo, X., Liu, L., Zhao, W., Li, X., Wang, X., Ning, A., Cao, J., Zhang, W., Cao, L., & Zhong, M. (2023) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.12905 · Cited by 26
Microbial Symphony: Exploring the Role of the Gut in Osteoarthritis-Related Pain. A Narrative Review
Corriero, A., Giglio, M., Soloperto, R., Inchingolo, F., Varrassi, G., & Puntillo, F. (2024) · Pain and Therapy · doi:10.1007/s40122-024-00602-9 · Cited by 28
IUPHAR themed review: The gut microbiome in schizophrenia
Kamath, S., Sokolenko, E., Collins, K., Chan, N. S. L., Mills, N. T., Clark, S. R., Marques, F. Z., & Joyce, P. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107561 · Cited by 26
Citrus Exosome-like Nanoparticles Reversed High-Fat Diet-Induced Microbiota Dysbiosis and Associated Short-Chain Fatty Acid Production
Zhan, M., Cai, Y., Zhao, C., Chen, B., Wang, X., Shen, P., Han, Y., Song, M., Cao, Y., & Xiao, H. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c04523 · Cited by 29
Short-Chain Fatty Acid Production and Functional Aspects on Host Metabolism
Tungland, B. C. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814649-1.00002-8 · Cited by 29
The effects of the supplementation of multi‐strain probiotics on intestinal microbiota, metabolites and inflammation of young SPF chickens challenged with Salmonella enterica subsp. enterica
Chang, C.-H., Teng, P.-Y., Lee, T.-T., & Yu, B. (2019) · Animal Science Journal · doi:10.1111/asj.13205 · Cited by 28
Alterations of the Rectal Microbiome Are Associated with the Development of Postoperative Ileus in Patients Undergoing Colorectal Surgery
Shogan, B. D., Chen, J., Duchalais, É., Collins, D., Chang, M. I., Krull, K. R., Krezalek, M. A., Larson, D. W., Walther-Antonio, M. R. S., Chia, N., et al. (2020) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-020-04593-8 · Cited by 26
The Indian gut microbiota—Is it unique?
Pulipati, P., Sarkar, P., Jakkampudi, A., Kaila, V., Sarkar, S., Unnisa, M., Reddy, D. N., Khan, M. R., & Talukdar, R. (2020) · Indian Journal of Gastroenterology · doi:10.1007/s12664-020-01037-8 · Cited by 26
Fructooligosaccharides supplementation mitigated chronic stress-induced intestinal barrier impairment and neuroinflammation in mice
Zhang, Y., Wang, P., Xia, C., Wu, Z., Zhong, Z., Ye, X., Zeng, Y., Liu, H., Liu, R., & Liao, M. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104060 · Cited by 27
Transverse aortic constriction induces gut barrier alterations, microbiota remodeling and systemic inflammation
Boccella, N., Paolillo, R., Coretti, L., D’Apice, S., Lama, A., Giugliano, G., Schiattarella, G. G., Cuomo, M., d’Aquino, I., Cavaliere, G., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-86651-y · Cited by 27
The Role of Gut Microbiota in Modulating Tumor Growth and Anticancer Agent Efficacy
Kim, J.-H., & Lee, H. K. (2021) · Molecules and Cells · doi:10.14348/molcells.2021.0032 · Cited by 27
Differences in Compositions of Oral and Fecal Microbiota between Patients with Obesity and Controls
Stefura, T., Zapała, B., Gosiewski, T., Skomarovska, O., Dudek, A., Pędziwiatr, M., & Major, P. (2021) · Medicina · doi:10.3390/medicina57070678 · Cited by 26
Comparative Analysis of the Fecal Bacterial Microbiota of Wintering Whooper Swans (Cygnus Cygnus)
Wang, W., Huang, S., Yang, L., & Zhang, G. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.670645 · Cited by 26
Potential prebiotic properties of exopolysaccharides produced by a novel Lactobacillus strain, Lactobacillus pentosus YY-112
Wang, M., Zhou, W., Yang, Y., Xing, J., Xu, X., & Lin, Y. (2021) · Food & Function · doi:10.1039/d1fo01261d · Cited by 26
The Gut Microbial-Derived Metabolite Trimethylamine N-Oxide and Atrial Fibrillation: Relationships, Mechanisms, and Therapeutic Strategies
Huang, R., Li, Y., & Lei, Y. (2021) · Clinical Interventions in Aging · doi:10.2147/cia.s339590 · Cited by 28
Lactobacillus plantarum MA2 Ameliorates Methionine and Choline-Deficient Diet Induced Non-Alcoholic Fatty Liver Disease in Rats by Improving the Intestinal Microecology and Mucosal Barrier
Wang, Y., Zhang, Y., Yang, J., Li, H., Wang, J., & Geng, W. (2021) · Foods · doi:10.3390/foods10123126 · Cited by 26
The Nutrition-Microbiota-Physical Activity Triad: An Inspiring New Concept for Health and Sports Performance
Boisseau, N., Barnich, N., & Koechlin‐Ramonatxo, C. (2022) · Nutrients · doi:10.3390/nu14050924 · Cited by 32
The Game for Three: Salmonella–Host–Microbiota Interaction Models
Grzymajło, K. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.854112 · Cited by 26
D-galactose Intake Alleviates Atopic Dermatitis in Mice by Modulating Intestinal Microbiota
Kim, D., Jung, D., Song, E.-J., Jang, A., Park, J., Ahn, J.-H., Lee, T., Kim, Y., Lee, Y., Seo, I.-S., et al. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.895837 · Cited by 26
Chronic ethanol exposure induced anxiety‐like behaviour by altering gut microbiota and GABA system
Yao, H., Zhang, D., Yu, H., Shen, H., Lan, X., Liu, H., Chen, X., Wu, X., Zhang, G., & Wang, X. (2022) · Addiction Biology · doi:10.1111/adb.13203 · Cited by 26
Substrate degradation pathways, conserved functions and community composition of the hindgut microbiota in the herbivorous marine fish Kyphosus sydneyanus
Stevenson, S. J. R., Lee, K. C. Y., Handley, K. M., Angert, E. R., White, W. L., & Clements, K. D. (2022) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2022.111283 · Cited by 26
Gut Microbiota and Fecal Microbiota Transplantation in Patients with Food Allergies: A Systematic Review
Jensen, C., Antonsen, M. F., & Lied, G. A. (2022) · Microorganisms · doi:10.3390/microorganisms10101904 · Cited by 27
Breast Cancer Survivors and Healthy Women: Could Gut Microbiota Make a Difference?—“BiotaCancerSurvivors”: A Case-Control Study
Caleça, T., Ribeiro, P., Vitorino, M. M., Menezes, M., Sampaio-Alves, M., Mendes, A. D., Vicente, R. S., Negreiros, I., Faria, A., & Costa, D. A. (2023) · Cancers · doi:10.3390/cancers15030594 · Cited by 26
Multi-omics profiling reveals potential alterations in rheumatoid arthritis with different disease activity levels
Chen, J., Li, S., Zhu, J., Su, W., Jian, C., Zhang, J., Wu, J., Wang, T., Zhang, W., Zeng, F., et al. (2023) · Arthritis Research & Therapy · doi:10.1186/s13075-023-03049-z · Cited by 30
Causal relationship between kidney stones and gut microbiota contributes to the gut-kidney axis: a two-sample Mendelian randomization study
Liu, M., Zhang, Y., Wu, J. H., Gao, M., Zhu, Z., & Chen, H. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1204311 · Cited by 27
The Interaction between Stress and Inflammatory Bowel Disease in Pediatric and Adult Patients
Belei, O., Basaca, D.-G., Olariu, L., Pantea, M., Bozgan, D., Nanu, A.-M., Sîrbu, I., Mărginean, O., & Enătescu, I. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13051361 · Cited by 30
The colon revisited or the key to wellness, health and disease
González-Correa, C.-A., Mulett-Vásquez, E., Miranda, D. A., González-Correa, C. H., & Buitrago, P. A. G. (2017) · Medical Hypotheses · doi:10.1016/j.mehy.2017.07.032 · Cited by 26
POTENTIAL PREVENTIVE EFFECT OF LACTOBACILLUS ACIDOPHILUS AND LACTOBACILLUS PLANTARUM IN PATIENTS WITH POLYPS OR COLORECTAL CÂNCER
ZINATIZADEH, N., Khalili, F., Fallah, P., Farid, M., GERAVAND, M., & Yaslianifard, S. (2018) · Arquivos de Gastroenterologia · doi:10.1590/s0004-2803.201800000-87 · Cited by 26
Interaction between high-fat diet and ethanol intake leads to changes on the fecal microbiome
Júnior, R. E. M., de Carvalho, L. M., Pedersen, A. S. B., Damasceno, S., Maioli, T. U., Faria, A. M. C., & Godard, A. L. B. (2019) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2019.07.006 · Cited by 27
Using Zebrafish to Investigate Interactions Between Xenobiotics and Microbiota
Catron, T. R., Gaballah, S., & Tal, T. L. (2019) · Current Pharmacology Reports · doi:10.1007/s40495-019-00203-7 · Cited by 26
The Interplay between Tumour Microenvironment Components in Malignant Melanoma
Amălinei, C., Grigoraş, A., Lozneanu, L., Căruntu, I.-D., Giuşcă, S. E., & Balan, R. A. (2022) · Medicina · doi:10.3390/medicina58030365 · Cited by 27
Konjac Glucomannan: A functional food additive for preventing metabolic syndrome
Jian, X., Jian, S., & Deng, B. (2024) · Journal of Functional Foods · doi:10.1016/j.jff.2024.106108 · Cited by 25
Gender-specific insights into the irritable bowel syndrome pathophysiology. Focus on gut dysbiosis and permeability
JohnBritto, J. S., Ciaula, A. D., Noto, A., Cassano, V., Sciacqua, A., Khalil, M., Portincasa, P., & Bonfrate, L. (2024) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2024.03.011 · Cited by 29
Prebiotic selection influencing inflammatory bowel disease treatment outcomes: a review of the preclinical and clinical evidence
Ariaee, A., Koentgen, S., Wardill, H. R., Hold, G. L., Prestidge, C. A., Armstrong, H., & Joyce, P. (2024) · eGastroenterology · doi:10.1136/egastro-2023-100055 · Cited by 27
Effect of weight loss program using prebiotics and probiotics on body composition, physique, and metabolic products: longitudinal intervention study
Hassan, N. E., El-Masry, S. A., Shebini, S. M. E., Ahmed, N. H., Mehanna, N. S., Wahed, M. M. A., Amine, D., Hashish, A. F., Selim, M. K., Afify, M. A. S., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-61130-2 · Cited by 30
Smart bionanomaterials for treatment and diagnosis of inflammatory bowel disease
Stojanov, S., & Berlec, A. (2024) · Nanotechnology Reviews · doi:10.1515/ntrev-2024-0057 · Cited by 25
Gut Dysbiosis Exacerbates Intestinal Absorption of Cadmium and Arsenic from Cocontaminated Rice in Mice Due to Impaired Intestinal Barrier Functions
Zhou, L., Chen, S.-Z., Li, Y., Xue, R.-Y., Duan, X., Lin, X.-Y., Chen, S., Zhou, D., & Li, H. (2025) · Environmental Science & Technology · doi:10.1021/acs.est.5c00817 · Cited by 25
The role of plant-based dietary compounds in gut microbiota modulation in inflammatory bowel disease
Akanyibah, F. A., He, C., Xiu, W., Wang, B., & Mao, F. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1606289 · Cited by 30
Gut microbiome remodeling in chronic kidney disease: implications of kidney replacement therapies and therapeutic interventions
Wang, Q., Han, Y., Pang, L., Zhou, Z., & Lijuan, D. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1620247 · Cited by 26
A Novel Insight at Atherogenesis: The Role of Microbiome
Kirichenko, T. V., Markina, Y. V., Sukhorukov, V. N., Khotina, V. A., Wu, W., & Orekhov, A. N. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.586189 · Cited by 25
Microbiome of the Aerodigestive Tract in Health and Esophageal Disease
Hasan, A., Hasan, L. K., Schnabl, B., Greytak, M., & Yadlapati, R. H. (2020) · Digestive Diseases and Sciences · doi:10.1007/s10620-020-06720-6 · Cited by 25
Lactiplantibacillus plantarum MG4296 and Lacticaseibacillus paracasei MG5012 Ameliorates Insulin Resistance in Palmitic Acid-Induced HepG2 Cells and High Fat Diet-Induced Mice
Won, G., Choi, S., Kang, C.-H., & Kim, G. (2021) · Microorganisms · doi:10.3390/microorganisms9061139 · Cited by 25
Gut Serpinome: Emerging Evidence in IBD
Mkaouar, H., Mariaule, V., Rhimi, S., Hernandez, J. L., Kriaa, A., Jablaoui, A., Akermi, N., Maguin, E., Lesner, A., Korkmaz, B., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22116088 · Cited by 23
Altered microbiomes of aquatic macroinvertebrates and riparian spiders downstream of municipal wastewater effluents
Millar, E. N., Surette, M. G., & Kidd, K. A. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.151156 · Cited by 25
Exposure to combustion derived particulate matter exacerbates influenza infection in neonatal mice by inhibiting IL22 production
Kumar, A., Patel, V., Harding, J. N., You, D., & Cormier, S. A. (2021) · Particle and Fibre Toxicology · doi:10.1186/s12989-021-00438-7 · Cited by 25
The Pathology and Physiology of Ileostomy
Ma, H., Li, X., Yang, H., Qiu, Y., & Xiao, W. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.842198 · Cited by 29
16S rRNA Gene Sequencing Reveals Specific Gut Microbes Common to Medicinal Insects
Geng, J., Sui, Z., Dou, W., Miao, Y., Wang, T., Wei, X., Chen, S., Zhang, Z., Xiao, J., & Huang, D. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.892767 · Cited by 26
Spice-Derived Bioactive Compounds Confer Colorectal Cancer Prevention via Modulation of Gut Microbiota
Dacrema, M., Ali, A., Ullah, H., Khan, A., Minno, A. D., Xiao, J., Martins, A. M. C., & Daglia, M. (2022) · Cancers · doi:10.3390/cancers14225682 · Cited by 27
Bacillus licheniformis reverses the environmental ceftriaxone sodium-induced gut microbial dysbiosis and intestinal inflammation in mice
Zeng, Z., Yue, W., Kined, C., Wang, P., Liu, R., Liu, J., & Chen, X. (2023) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.114890 · Cited by 26
The Role of Gut Microbiota in the Clinical Outcome of Septic Patients: State of the Art and Future Perspectives
Marascio, N., Scarlata, G. G. M., Romeo, F., Cicino, C., Trecarichi, E. M., Quirino, A., Torti, C., Matera, G., & Russo, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24119307 · Cited by 25
Efficacy and safety of probiotics and synbiotics for functional constipation in children: A systematic review and meta-analysis of randomized clinical trials
Liu, L., Wang, A., Shi, H., Tao, H., & Nahata, M. C. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.08.015 · Cited by 29
Targeting gut microbiota and immune crosstalk: potential mechanisms of natural products in the treatment of atherosclerosis
Jing, J., Guo, J., Dai, R., Zhu, C., & Zhang, Z. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1252907 · Cited by 28
Multiple Infectious Agents and the Origins of Atherosclerotic Coronary Artery Disease
Lawson, J. S. (2016) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2016.00030 · Cited by 25
Exploring the Impact of Food on the Gut Ecosystem Based on the Combination of Machine Learning and Network Visualization
Shima, H., Masuda, S., Date, Y., Shino, A., Tsuboi, Y., Kajikawa, M., Inoue, Y. H., Kanamoto, T., & Kikuchi, J. (2017) · Nutrients · doi:10.3390/nu9121307 · Cited by 27
Dairy and Nondairy-Based Beverages as a Vehicle for Probiotics, Prebiotics, and Symbiotics: Alternatives to Health Versus Disease Binomial Approach Through Food
Tesfaye, W., Suárez-Lepe, J. A., Loira, I., Palomero, F., & Morata, A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815504-2.00014-1 · Cited by 28
Gut Microbiota between Environment and Genetic Background in Familial Mediterranean Fever (FMF)
Ciaula, A. D., Stella, A., Bonfrate, L., Wang, D. Q. ‐., & Portincasa, P. (2020) · Genes · doi:10.3390/genes11091041 · Cited by 25
A Systematic Review of the Toxicokinetics of Micro- and Nanoplastics in Mammals Following Digestive Exposure
Popa, R., & Tăbăran, F. (2025) · Applied Sciences · doi:10.3390/app15116135 · Cited by 28
In silico approach for mining of potential drug targets from hypothetical proteins of bacterial proteome
Omeershffudin, U. N. M., & Kumar, S. (2019) · International Journal of Molecular Biology Open Access · doi:10.15406/ijmboa.2019.04.00111 · Cited by 24
Gut microbiota in coronary artery disease: a friend or foe?
Zhang, B., Wang, X., Ran, X., & Li, C. (2020) · Bioscience Reports · doi:10.1042/bsr20200454 · Cited by 25
Inflammation-Associated Microbiota Composition Across Domestic Animals
Hashimoto‐Hill, S., & Alenghat, T. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.649599 · Cited by 24
Distinct Human Gut Microbial Taxonomic Signatures Uncovered With Different Sample Processing and Microbial Cell Disruption Methods for Metaproteomic Analysis
García-Durán, C., Martínez‐López, R., Zapico, I., Pérez, E., Romeu, E., Arroyo, J., Hernáez, M. L., Pitarch, A., Monteoliva, L., & Gil, C. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.618566 · Cited by 23
The Role of Microbiota in the Pathogenesis of Esophageal Adenocarcinoma
Gillespie, M., Rai, V., Agrawal, S., & Nandipati, K. C. (2021) · Biology · doi:10.3390/biology10080697 · Cited by 24
Integrated Plasma Metabolomics and Gut Microbiota Analysis: The Intervention Effect of Jiawei Xiaoyao San on Liver Depression and Spleen Deficiency Liver Cancer Rats
Li, Z., Zhao, Y., Cheng, J., Xu, L., Wen, X., Sun, Y., Xia, M., & He, Y. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.906256 · Cited by 27
Identification of the DPP-IV Inhibitory Peptides from Donkey Blood and Regulatory Effect on the Gut Microbiota of Type 2 Diabetic Mice
Ma, C., Liu, D., Hao, H., & Wu, X. (2022) · Foods · doi:10.3390/foods11142148 · Cited by 23
Analysis of gut microbiome composition, function, and phenotype in patients with osteoarthritis
Liu, S., Li, G., Zhu, Y., Xu, C., Yang, Q. L., Xiong, A., Weng, J., Yu, F., & Zeng, H. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.980591 · Cited by 23
The impact of exclusive enteral nutrition on the gut microbiome and bile acid metabolism in pediatric Crohn's disease
Lv, Y., Lou, Y., Liu, A., Cheng, Q., Yang, G., Xu, C., Luo, Y., Lou, J., Yu, J., Fang, Y., et al. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2022.11.018 · Cited by 26
Algal oil alleviates antibiotic-induced intestinal inflammation by regulating gut microbiota and repairing intestinal barrier
Zhang, H., Xu, Z., Chen, W., Huang, F., Chen, S., Wang, X., & Yang, C. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1081717 · Cited by 24
Protective Effect of Lactiplantibacillus plantarum subsp. plantarum SC-5 on Dextran Sulfate Sodium—Induced Colitis in Mice
Shi, R., Yu, F., Hu, X., Liu, Y., Jin, Y., Ren, H., Lu, S., Guo, J., Chang, J., Li, Y., et al. (2023) · Foods · doi:10.3390/foods12040897 · Cited by 24
Targeting Gut Microbiota for the Treatment of Primary Biliary Cholangitis: From Bench to Bedside
Zhang, L., Yang, L., & Chu, H. (2023) · Journal of Clinical and Translational Hepatology · doi:10.14218/jcth.2022.00408 · Cited by 24
Probiotic modulation of gut microbiota by Bacillus coagulans MTCC 5856 in healthy subjects: A randomized, double-blind, placebo-control study
Majeed, M. A., Nagabhushanam, K., Mundkur, L., Paulose, S., Divakar, H., Rao, S., & Arumugam, S. (2023) · Medicine · doi:10.1097/md.0000000000033751 · Cited by 25
Octahedron Iron Oxide Nanocrystals Prohibited Clostridium difficile Spore Germination and Attenuated Local and Systemic Inflammation
Lee, W., Wu, Y., Chen, Y., Wu, S.-R., Shih, T.-M., Li, T., Yang, L., Yeh, C., Tsai, P.-J., & Shieh, D.-B. (2017) · Scientific Reports · doi:10.1038/s41598-017-08387-y · Cited by 24
High‐sugar diet intake, physical activity, and gut microbiota crosstalk: Implications for obesity in rats
Neves, V. G. D. O., de Oliveira, D. T., Oliveira, D. C., Perucci, L. O., dos Santos, T. A. P., Fernandes, I. D. C., de Sousa, G. G., Barboza, N. R., & Guerra‐Sá, R. (2020) · Food Science & Nutrition · doi:10.1002/fsn3.1842 · Cited by 24
Gut Microbiota Modulation for Therapeutic Management of Various Diseases: A New Perspective Using Stem Cell Therapy
Ahmed, L. A., & Al‐Massri, K. F. (2022) · Current Molecular Pharmacology · doi:10.2174/1874467215666220222105004 · Cited by 23
Gastrointestinal microbiota-directed nutritional and therapeutic interventions for inflammatory bowel disease: opportunities and challenges
Paudel, D., Nair, D. V. T., Joseph, G., Castro, R., Tiwari, A. K., & Singh, V. (2023) · Gastroenterology report · doi:10.1093/gastro/goae033 · Cited by 26
Microbiota-Derived Short-Chain Fatty Acids Boost Antitumoral Natural Killer Cell Activity
Pérez, M., Buey, B., Sánchez‐Corral, P., Giraldos, D., & Latorre, E. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13133885 · Cited by 24
Harnessing Gut Microbiota for Biomimetic Innovations in Health and Biotechnology
Beltrán-Velasco, A. I., & Clemente‐Suárez, V. J. (2025) · Biomimetics · doi:10.3390/biomimetics10020073 · Cited by 25
Exploring the role of oral bacteria in oral cancer: a narrative review
Mivehchi, H., Eskandari-Yaghbastlo, A., Bahrami, P. P., Elhami, A., Faghihinia, F., Nejati, S. T., Kazemi, K. S., & Nabi‐Afjadi, M. (2025) · Discover Oncology · doi:10.1007/s12672-025-01998-2 · Cited by 26
New insights into gut microbiota–prostate cancer crosstalk
Laaraj, J., Lachance, G., Bergeron, A., Fradet, Y., Robitaille, K., & Fradet, V. (2025) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2025.03.015 · Cited by 25
Gut Microbiota‐Derived Metabolites Orchestrate Metabolic Reprogramming in Diabetic Cardiomyopathy: Mechanisms and Therapeutic Frontiers
Jin, J., Yang, X., Feng, R., Ye, M.-L., Xu, H., Wang, J., Hu, J., Zuo, H., Lu, J., Song, J., et al. (2025) · The FASEB Journal · doi:10.1096/fj.202501579rr · Cited by 24
Gut microbiota-mediated immunomodulation underlies the anti-tumor effects of a novel ginseng polysaccharide
Li, C., Zhou, S., Chen, S., Xu, Z., Xue, Q., Wang, H., Liu, T., Chen, W., Feng, J., Chen, J., et al. (2025) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2025.124458 · Cited by 23
Short Communication: Anatomic Site of Sampling and the Rectal Mucosal Microbiota in HIV Negative Men Who Have Sex with Men Engaging in Condomless Receptive Anal Intercourse
Pescatore, N. A., Pollak, R. M., Kraft, C. S., Mulle, J. G., & Kelley, C. F. (2018) · AIDS Research and Human Retroviruses · doi:10.1089/aid.2017.0206 · Cited by 23
Comparative analysis of intestinal bacteria among venom secretion and non-secrection snakes
Qin, Z., Wang, S., Guo, D., Zhu, J., Chen, H., Bai, L., Luo, X., & Yin, Y. (2019) · Scientific Reports · doi:10.1038/s41598-019-42787-6 · Cited by 23
Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice
Jun, S., Cheema, A. K., Bose, C., Boerma, M., Palade, P., Carvalho, E., Awasthi, S., & Singh, S. P. (2020) · Microorganisms · doi:10.3390/microorganisms8101500 · Cited by 23
Vitamin B12 Enriched in Spinach and its Effects on Gut Microbiota
Zheng, Y., Xiang, S., Zhang, H., Ye, K., Zhang, Y., Yin, G., Feng, X., Bao, X., Chen, J., & Zhu, X. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c07597 · Cited by 25
Modulating Gut Microbiota: An Emerging Approach in the Prevention and Treatment of Multiple Sclerosis
Ullah, H., Товчига, О. В., Daglia, M., & Khan, H. Z. (2021) · Current Neuropharmacology · doi:10.2174/1570159x19666210217084827 · Cited by 25
Gut Lactobacillus Level Is a Predictive Marker for Coronary Atherosclerotic Lesions Progress and Prognosis in Patients With Acute Coronary Syndrome
Gao, J., Wang, J., Zhao, L., Yao, T., Chen, Y., Ma, J., Zhang, X., Wang, J.-X., Wang, Y., Cui, Z., et al. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.687827 · Cited by 23
A unique gut microbiota signature in pulmonary arterial hypertension: A pilot study
Jose, A., Apewokin, S. K., Hussein, W. E., Ollberding, N. J., Elwing, J., & Haslam, D. B. (2022) · Pulmonary Circulation · doi:10.1002/pul2.12051 · Cited by 22
Dietary flavonoids: a novel strategy for the amelioration of cognitive impairment through intestinal microbiota
Zhang, Y., Cheng, L., Liu, Y., Zhan, S., Wu, Z., Luo, S., & Zhang, X. (2022) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.12151 · Cited by 23
Murine response to the opportunistic bacterium Pseudomonas aeruginosa infection in gut dysbiosis caused by 5-fluorouracil chemotherapy-induced mucositis
Santana, A. B., Souto, B. S., Santos, N. C. D. M., Pereira, J. A., Tagliati, C. A., Novaes, R. D., Corsetti, P. P., & de Almeida, L. A. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120890 · Cited by 23
Sestrin2 suppresses ferroptosis to alleviate septic intestinal inflammation and barrier dysfunction
Liu, W., Xu, C., Zou, Z., Weng, Q., & Xiao, Y. (2022) · Immunopharmacology and Immunotoxicology · doi:10.1080/08923973.2022.2121927 · Cited by 23
Resveratrol Attenuates Ankylosing Spondylitis in Mice by Inhibiting the TLR4/NF-κB/NLRP3 Pathway and Regulating Gut Microbiota
Ding, M.-H., Xu, P.-G., Wang, Y., Ren, B.-D., & Zhang, J. (2022) · Immunological Investigations · doi:10.1080/08820139.2022.2154162 · Cited by 23

Authors: Jandhyala, S. M.
Venue: World Journal of Gastroenterology
Publisher: Baishideng Publishing Group Inc.
Published: 2015
Volume: 21
Issue: 29
Pages: 8787
ISSN: 1007-9327 (ISSN-L)
DOI: 10.3748/wjg.v21.i29.8787
PMC: PMC4528021
OpenAlex: W1420654867
Cited by: 3,001
References: 163
Citations by year: 2026: 170 · 2025: 382 · 2024: 491 · 2023: 439 · 2022: 391 · 2021: 366 · 2020: 266 · 2019: 205 · 2018: 142 · 2017: 102 · 2016: 36 · 2015: 4
FWCI: 9.18
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc
Locations: World Journal of Gastroenterology (publishedVersion, cc-by-nc)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
Keywords: gut microbiota, Bacteroidetes, Firmicutes, infant gut colonization, nutrient metabolism, gut mucosal barrier, immunomodulation, pathogen protection, mode of delivery, breast milk, infant formula, diet, antibiotic use, antibiotic resistance genes, horizontal gene transfer, multidrug resistance
MeSH terms: Bacillota, Gastrointestinal Microbiome, Age Factors, Anti-Bacterial Agents, Bacteriological Techniques, Diet, Health Status, Homeostasis, Humans, Intestines, Computational Biology, Probiotics, Bacteroidetes, Host-Pathogen Interactions, Prebiotics, Synbiotics

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Role of the normal gut microbiota

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks