The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
The Mouse Forced Swim Test
Open accessAbstract
The forced swim test is a rodent behavioral test used for evaluation of antidepressant drugs, antidepressant efficacy of new compounds, and experimental manipulations that are aimed at rendering or preventing depressive-like states. Mice are placed in an inescapable transparent tank that is filled with water and their escape related mobility behavior is measured. The forced swim test is straightforward to conduct reliably and it requires minimal specialized equipment. Successful implementation of the forced swim test requires adherence to certain procedural details and minimization of unwarranted stress to the mice. In the protocol description and the accompanying video, we explain how to conduct the mouse version of this test with emphasis on potential pitfalls that may be detrimental to interpretation of results and how to avoid them. Additionally, we explain how the behaviors manifested in the test are assessed.
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Citations
Cites
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Cited by
Can, A., Dao, D. T., Terrillion, C. E., Piantadosi, S. C., Bhat, S., & Gould, T. D. (2011) · Journal of Visualized Experiments · doi:10.3791/3769 · Cited by 526
Self-citationMcMorris, T., & Hale, B. J. (2012) · Brain and Cognition · doi:10.1016/j.bandc.2012.09.001 · Cited by 516
FGF21 Regulates Sweet and Alcohol Preference
Talukdar, S., Owen, B. M., Song, P., Hernandez, G., Zhang, Y., Zhou, Y., Scott, W. T., Paratala, B., Turner, T., Smith, A., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2015.12.008 · Cited by 342
GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior
Hunt, R. F., Girskis, K. M., Rubenstein, J. L., Alvarez-Buylla, A., & Baraban, S. C. (2013) · Nature Neuroscience · doi:10.1038/nn.3392 · Cited by 301
Identification of a choroid plexus vascular barrier closing during intestinal inflammation
Carloni, S., Bertocchi, A., Mancinelli, S., Bellini, M., Erreni, M., Borreca, A., Braga, D., Giugliano, S., Mozzarelli, A. M., Manganaro, D., et al. (2021) · Science · doi:10.1126/science.abc6108 · Cited by 268
Metadata
- Authors
- Can, A., Dao, D. T., Arad, M., Terrillion, C. E., Piantadosi, S. C., & Gould, T. D.
- Venue
- Journal of Visualized Experiments
- Publisher
- MyJove Corporation
- Published
- 2011-12-11
- Issue
- 58
- Pages
- e3638-e3638
- ISSN
- 1940-087X (ISSN-L)
- DOI
- 10.3791/3638
- OpenAlex
- W2073658789
- Cited by
- 521
- References
- 29
- FWCI
- 1.88
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Can, A., Dao, D. T., Arad, M., Terrillion, C. E., Piantadosi, S. C., & Gould, T. D. (2011). The Mouse Forced Swim Test. Journal of Visualized Experiments. https://doi.org/10.3791/3638
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
