Photodynamic therapy: A hot topic in dermato-oncology (Review)
Open accessAbstract
Photodynamic therapy (PDT) is a modern, non-invasive therapeutic method used for the destruction of various cells and tissues. It requires the simultaneous presence of three components: a photosensitizer (PS), a light source and oxygen. Precancerous skin lesions are conditions associated with a high likelihood of malignant transformation to squamous cell carcinoma. Data available so far indicate that PDT is a promising treatment method which can be successfully employed in several medical fields including dermatology, urology, ophthalmology, pneumology, cardiology, dentistry and immunology. Numerous authors therefore have studied this technique in order to improve its efficacy. As a result, significant advancement has been achieved with regard to PSs and drug delivery systems. Substantial progress was also obtained with respect to PDT for the treatment of precancerous skin lesions, several authors focusing their efforts on the study of daylight-PDT and on identifying methods of decreasing technique-related pain. This review reports on the most recent findings in PDT, with emphasis on cutaneous precancerous lesions.
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Blue light (450 to 495 nm) is used to maximize absorbance and longer wavelengths of light (beyond 620 nm) have best tissue penetration.
“Blue light (450 to 495 nm) is used to maximize absorbance and longer wavelengths of light (beyond 620 nm) have best tissue penetration.107,108”
From Effect of skin color on optical properties and the implications for medical optical technologies: a review (2024) · cites this paper as [107]
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Use of photodynamic therapy and acitretin in generalized eruptive keratoacanthoma of Grzybowski
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Erythroplasia of Queyrat treated with methyl aminolevulinate-photodynamic therapy
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Biological therapies in psoriasis - revisited
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Transcriptomics in Cancer - Stages Toward Patents in Biomarkers?
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Photodynamic Therapy: A Compendium of Latest Reviews
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Utility of Photodynamic Therapy in Dentistry: Current Concepts
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Deciphering UV‐induced DNA Damage Responses to Prevent and Treat Skin Cancer
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Photodynamic Therapy in Primary Breast Cancer
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Nano-photosensitizers for enhanced photodynamic therapy
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Tumour Microenvironment in Skin Carcinogenesis
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Polymyxin-based photosensitizer for the potent and selective killing of Gram-negative bacteria
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Emerging Applications of Optical Fiber-Based Devices for Brain Research
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Highly Phototoxic Transplatin‐Modified Distyryl‐BODIPY Photosensitizers for Photodynamic Therapy
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An Updated Review of the Therapeutic Management of Keratoacanthomas.
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Mansuri, P., Tabaie, S. M., Naderi, M. S., Kebriti, K., Djavid, G. E., & Shirkavand, A. (2022) · Journal of lasers in medical sciences · doi:10.34172/jlms.2022.44 · Cited by 5 · see citing works
Therapeutic applications of carbon nanodots synthesized from green (re)sources
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- Authors
- Tampa, M., Sarbu, M.-I., Matei, C., Mitran, C.-I., Mitran, M.-I., Caruntu, C., Constantin, C., Neagu, M., & Georgescu, S.-R.
- Affiliations
- Carol Davila University of Medicine and Pharmacy (RO)
- Department of Dermatology, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania
- Department of Dermatology, ‘Victor Babes’ Hospital, 030303 Bucharest, Romania
- Department of of Physiology, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania
- Institutul National Victor Babes (RO)
- ORCID
- Venue
- Oncology Letters
- Publisher
- Spandidos Publications
- Published
- 2019-01-16
- Volume
- 17
- Issue
- 5
- Pages
- 4085-4093
- ISSN
- 1792-1074 (ISSN-L)
- 1792-1082
- PMC
- PMC6444307
- OpenAlex
- W2908577291
- Cited by
- 72
- References
- 110
- Citations by year
- 2026: 2 · 2024: 1 · 2023: 12 · 2022: 10 · 2021: 16 · 2020: 26 · 2019: 5
- FWCI
- 2.40
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Oncology Letters (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
- Health Sciences › Medicine › Epidemiology › Nonmelanoma Skin Cancer Studies
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Keywords
- photodynamic therapy, photosensitizers, precancerous skin lesions, squamous cell carcinoma, daylight photodynamic therapy, drug delivery systems, treatment-related pain, non-invasive cancer treatment
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