Light Sources and Dosimetry Techniques for Photodynamic Therapy

Kim, Michele M.; Darafsheh, Arash

doi:10.1111/php.13219

Cited by 454Photodynamic Therapy Research StudiesOptical Imaging and Spectroscopy TechniquesNanoplatforms for cancer theranostics

Light Sources and Dosimetry Techniques for Photodynamic Therapy

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Kim, Michele M., Darafsheh, Arash·2020·Photochemistry and Photobiology

DOI 10.1111/php.13219

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Abstract

Effective treatment delivery in photodynamic therapy (PDT) requires coordination of the light source, the photosensitizer, and the delivery device appropriate to the target tissue. Lasers, light‐emitting diodes (LEDs), and lamps are the main types of light sources utilized for PDT applications. The choice of light source depends on the target location, photosensitizer used, and light dose to be delivered. Geometry of minimally accessible areas also plays a role in deciding light applicator type. Typically, optical fiber‐based devices are used to deliver the treatment light close to the target. The optical properties of tissue also affect the distribution of the treatment light. Treatment light undergoes scattering and absorption in tissue. Most tissue will scatter light, but highly pigmented areas will absorb light, especially at short wavelengths. This review will summarize the basic physics of light sources, and describe methods for determining the dose delivered to the patient.

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Light Scattering by Small Particles
van de Hulst, H. C. (1981) · CERN Document Server (European Organization for Nuclear Research) · Cited by 7,924 · see citing works
Photodynamic Therapy
Dougherty, T. J., Gomer, C. J., Henderson, B. W., Jori, G., Kessel, D., Korbelik, M., Moan, J., & Peng, Q. (1998) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/90.12.889 · Cited by 4,716 · see citing works
Photodynamic Therapy
Gomer, C. J. (1988) · Cited by 4,169 · see citing works
Fundamentals of Photonics
Culshaw, B., & López-Higuera, J. M. (2012) · CRC Press eBooks · doi:10.1201/b13065-1 · Cited by 3,725 · see citing works
Nanoparticles in Photodynamic Therapy
Lucky, S. S., Soo, K. C., & Zhang, Y. (2015) · Chemical Reviews · doi:10.1021/cr5004198 · Cited by 2,999 · see citing works
A review of the optical properties of biological tissues
Cheong, W. F., Prahl, S. A., & Welch, A. J. (1990) · IEEE Journal of Quantum Electronics · doi:10.1109/3.64354 · Cited by 2,530 · see citing works
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
Celli, J. P., Spring, B. Q., Rizvi, I., Evans, C. L., Samkoe, K. S., Verma, S., Pogue, B. W., & Hasan, T. G. (2010) · Chemical Reviews · doi:10.1021/cr900300p · Cited by 2,334 · see citing works
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
Zhou, Z., Song, J., Nie, L., & Chen, X. S. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00271d · Cited by 2,104 · see citing works
Overcoming the Achilles' heel of photodynamic therapy
Fan, W., Huang, P., & Chen, X. S. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00616g · Cited by 1,686 · see citing works
Porphyrin and Nonporphyrin Photosensitizers in Oncology: Preclinical and Clinical Advances in Photodynamic Therapy
O’Connor, A. E., Gallagher, W. M., & Byrne, A. T. (2009) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2009.00585.x · Cited by 1,191 · see citing works
Fundamentals of photonics
(2007) · Choice Reviews Online · doi:10.5860/choice.45-0306 · Cited by 1,169 · see citing works
Photosensitizers in clinical PDT
Allison, R. R., Downie, G., Cuenca, R. E., Hu, X., Childs, C. J. H., & Sibata, C. H. (2004) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/s1572-1000(04)00007-9 · Cited by 1,061 · see citing works
Effect of wavelength and beam width on penetration in light-tissue interaction using computational methods
Ash, C., Dubec, M., Donne, K., & Bashford, T. (2017) · Lasers in Medical Science · doi:10.1007/s10103-017-2317-4 · Cited by 1,040 · see citing works
THE PHOTODEGRADATION OF PORPHYRINS IN CELLS CAN BE USED TO ESTIMATE THE LIFETIME OF SINGLET OXYGEN
Moan, J. E., & Berg, K. (1991) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1991.tb03669.x · Cited by 1,010 · see citing works
The physics, biophysics and technology of photodynamic therapy
Wilson, B. C., & Patterson, M. S. (2008) · Physics in Medicine and Biology · doi:10.1088/0031-9155/53/9/r01 · Cited by 1,009 · see citing works
Type I and Type II Photosensitized Oxidation Reactions: Guidelines and Mechanistic Pathways
Baptista, M. S., Cadet, J., Mascio, P. D., Ghogare, A. A., Greer, A., Hamblin, M. R., Lorente, C., Núñez, S. C., Ribeiro, M. S., Thomas, A. H., et al. (2017) · Photochemistry and Photobiology · doi:10.1111/php.12716 · Cited by 924 · see citing works
Methylene blue in photodynamic therapy: From basic mechanisms to clinical applications
Tardivo, J. P., del Giglio, A., de Oliveira, C. S., Gabrielli, D. S., Junqueira, H. C., Tada, D. B., Severino, D., Turchiello, R. F., & Baptista, M. S. (2005) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/s1572-1000(05)00097-9 · Cited by 922 · see citing works
Photodynamic therapeutics: basic principles and clinical applications
Sharman, W. M., Allen, C. M., & van Lier, J. E. (1999) · Drug Discovery Today · doi:10.1016/s1359-6446(99)01412-9 · Cited by 922 · see citing works
Dye Sensitizers for Photodynamic Therapy
Ormond, A., & Freeman, H. (2013) · Materials · doi:10.3390/ma6030817 · Cited by 847 · see citing works
Review of tissue simulating phantoms for optical spectroscopy, imaging and dosimetry
Pogue, B. W., & Patterson, M. S. (2006) · Journal of Biomedical Optics · doi:10.1117/1.2335429 · Cited by 842 · see citing works
Oncologic photodynamic therapy photosensitizers: A clinical review
Allison, R. R., & Sibata, C. H. (2010) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2010.02.001 · Cited by 840 · see citing works
Dye lasers
Schäfer, F. P. (1973) · Cited by 728 · see citing works
Quantum dots and nanoparticles for photodynamic and radiation therapies of cancer
Juzenas, P., Chen, W., Sun, Y.-P., Coelho, M. A. N., Generalov, R., Generalova, N., & Christensen, I. L. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.08.004 · Cited by 610 · see citing works
Biomedical Photonics Handbook
(2003) · CRC Press eBooks · doi:10.1201/9780203008997 · Cited by 606 · see citing works
Optical properties of intralipid: A phantom medium for light propagation studies
Flock, S. T., Jacques, S. L., Wilson, B. C., Star, W. M., & van Gemert, M. J. C. (1992) · Lasers in Surgery and Medicine · doi:10.1002/lsm.1900120510 · Cited by 573 · see citing works
Mechanisms of Action of Photodynamic Therapy with Verteporfin for the Treatment of Age-Related Macular Degeneration
Schmidt-Erfurth, U., & Hasan, T. G. (2000) · Survey of Ophthalmology · doi:10.1016/s0039-6257(00)00158-2 · Cited by 519 · see citing works
Laser and Non-laser Light Sources for Photodynamic Therapy
Brancaleon, L., & Moseley, H. (2002) · Lasers in Medical Science · doi:10.1007/s101030200027 · Cited by 485 · see citing works
Guidelines for topical photodynamic therapy: update
Morton, C. A., McKenna, K. E., & Rhodes, L. E. (2008) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2008.08882.x · Cited by 469 · see citing works
Beyond the Barriers of Light Penetration: Strategies, Perspectives and Possibilities for Photodynamic Therapy
Mallidi, S., Anbil, S. R., Bulin, A., Obaid, G., Ichikawa, M., & Hasan, T. G. (2016) · Theranostics · doi:10.7150/thno.16183 · Cited by 453 · see citing works
PHOTODYNAMIC THERAPY OF MALIGNANT TUMOURS
Diamond, I., McDonagh, A. F., Wilson, C., Granelli, S. G., Nielsen, S. L., & Jaenicke, R. (1972) · The Lancet · doi:10.1016/s0140-6736(72)92596-2 · Cited by 424 · see citing works
Implicit and explicit dosimetry in photodynamic therapy: a New paradigm
Wilson, B. C., Patterson, M. S., & Lilge, L. D. (1997) · Lasers in Medical Science · doi:10.1007/bf02765099 · Cited by 411 · see citing works
Breaking the depth dependency of phototherapy with Cerenkov radiation and low-radiance-responsive nanophotosensitizers
Kotagiri, N., Sudlow, G. P., Akers, W. J., & Achilefu, S. A. (2015) · Nature Nanotechnology · doi:10.1038/nnano.2015.17 · Cited by 403 · see citing works
Oxygen Consumption and Diffusion Effects in Photodynamic Therapy
Foster, T. H., Murant, R. S., Bryant, R. G., Knox, R. S., Gibson, S. L., & Hilf, R. (1991) · Radiation Research · doi:10.2307/3577919 · Cited by 400 · see citing works
PHOTODYNAMIC THERAPY
Dougherty, T. J. (1993) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1993.tb04990.x · Cited by 394 · see citing works
A review of <i>in‐vivo</i> optical properties of human tissues and its impact on PDT
Sandell, J. L., & Zhu, T. C. (2011) · Journal of Biophotonics · doi:10.1002/jbio.201100062 · Cited by 384 · see citing works
Quantum dots as photosensitizers?
Bakalova, R., Ohba, H., Zhelev, Z., et al. (2004) · Nature Biotechnology · doi:10.1038/nbt1104-1360 · Cited by 382 · see citing works
The physics of photodynamic therapy
Wilson, B. C., & Patterson, M. S. (1986) · Physics in Medicine and Biology · doi:10.1088/0031-9155/31/4/001 · Cited by 340 · see citing works
Photodynamic therapy for cancer of the pancreas
Bown, S. G., Rogowska, A., Whitelaw, D. E., Lees, W. R., Lovat, L. B., Ripley, P. M., Jones, L., Wyld, P., Gillams, A. R., & Hatfield, A. R. (2002) · Gut · doi:10.1136/gut.50.4.549 · Cited by 336 · see citing works
Photodynamic therapy vs. cryosurgery of basal cell carcinomas: results of a phase III clinical trial
Wang, I., Bendsøe, N., af Klinteberg, C., Enejder, A. M. K., Andersson‐Engels, S., Svanberg, S. R., & Svanberg, K. (2001) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2001.04141.x · Cited by 305 · see citing works
Oxygen in Human Tumors: Correlations between Methods of Measurement and Response to Therapy: Summary of a Workshop Held November 19-20, 1992, at the National Cancer Institute, Bethesda, Maryland
Stone, H. B., Brown, J. M., Phillips, T. L., & Sutherland, R. M. (1993) · Radiation Research · doi:10.2307/3578556 · Cited by 303 · see citing works
Quantum Dot‐based Energy Transfer: Perspectives and Potential for Applications in Photodynamic Therapy
Samia, A. C. S., Dayal, S., & Burda, C. (2006) · Photochemistry and Photobiology · doi:10.1562/2005-05-11-ir-525 · Cited by 299 · see citing works
PORPHYRIN PHOTOSENSITIZATION AND PHOTOTHERAPY
Moan, J. E. (1986) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1986.tb05647.x · Cited by 295 · see citing works
Photodynamic Therapy (PDT) for Lung Cancers
Usuda, J., Kato, H., Okunaka, T., Furukawa, K., Tsutsui, H., Yamada, K., Suga, Y., Honda, H., Nagatsuka, Y., Ohira, T., et al. (2006) · Journal of Thoracic Oncology · doi:10.1016/s1556-0864(15)31616-6 · Cited by 294 · see citing works
5-aminolevulinic acid photodynamic therapy for the treatment of high-grade gliomas
Mahmoudi, K., Garvey, K. L., Bouras, A., Cramer, G. M., Stepp, H. G., Raj, J. G. J., Bozec, D., Busch, T. M., & Hadjipanayis, C. G. (2019) · Journal of Neuro-Oncology · doi:10.1007/s11060-019-03103-4 · Cited by 293 · see citing works
Molecular photosensitisers for two-photon photodynamic therapy
Bolze, F., Jenni, S., Sour, A., & Heitz, V. (2017) · Chemical Communications · doi:10.1039/c7cc06133a · Cited by 273 · see citing works
Reduction of tumour oxygenation during and after photodynamic therapy in vivo: effects of fluence rate
Sitnik, T., Hampton, J., & Henderson, B. (1998) · British Journal of Cancer · doi:10.1038/bjc.1998.231 · Cited by 260 · see citing works
The role of photodynamic therapy (PDT) physics
Zhu, T. C., & Finlay, J. C. (2008) · Medical Physics · doi:10.1118/1.2937440 · Cited by 247 · see citing works
Lasers and light sources for PDT: past, present and future
Mang, T. S. (2004) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/s1572-1000(04)00012-2 · Cited by 237 · see citing works
Tumor-targeting multi-functional nanoparticles for theragnosis: New paradigm for cancer therapy
Ryu, J. H., Koo, H., Sun, I., Yuk, S. H., Choi, K., Kim, K., & Kwon, I. C. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.06.012 · Cited by 235 · see citing works
Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy
Yu, G., Durduran, T., Zhou, C., Wang, H.-W., Putt, M. E., Saunders, H., Sehgal, C. M., GLATSTEIN, E. J., Yodh, A. G., & Busch, T. M. (2005) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-04-2582 · Cited by 235 · see citing works
Singlet Oxygen Luminescence Dosimetry (SOLD) for Photodynamic Therapy: Current Status, Challenges and Future Prospects
Jarvi, M. T., Niedre, M. J., Patterson, M. S., et al. (2006) · Photochemistry and Photobiology · doi:10.1562/2006-05-03-ir-891 · Cited by 227 · see citing works
Cell Death Pathways Associated with Photodynamic Therapy: An Update
Kessel, D. H., & Oleinick, N. L. (2017) · Photochemistry and Photobiology · doi:10.1111/php.12857 · Cited by 224 · see citing works
Photodynamic Therapy With Verteporfin for Choroidal Neovascularization Caused by Age-related Macular Degeneration
Miller, J. W. (1999) · Archives of Ophthalmology · doi:10.1001/archopht.117.9.1161 · Cited by 221 · see citing works
Fluence rate as a modulator of PDT mechanisms
Henderson, B. W., Busch, T. M., & Snyder, J. W. (2006) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20327 · Cited by 217 · see citing works
In vivo wireless photonic photodynamic therapy
Bansal, A., Yang, F., Tian, X., Zhang, Y., & Ho, J. S. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1717552115 · Cited by 211 · see citing works
Prediction of Tumor Recurrence and Therapy Monitoring Using Ultrasound-Guided Photoacoustic Imaging
Mallidi, S., Watanabe, K., Timerman, D., Schoenfeld, D., & Hasan, T. G. (2015) · Theranostics · doi:10.7150/thno.10155 · Cited by 200 · see citing works
mTHPC‐mediated photodynamic therapy for early oral squamous cell carcinoma
Hopper, C., Kübler, A. C., Lewis, H., et al. (2004) · International Journal of Cancer · doi:10.1002/ijc.20209 · Cited by 196 · see citing works
Interstitial Photodynamic Therapy—A Focused Review
Shafirstein, G., Bellnier, D. A., Oakley, E., Hamilton, S., Potasek, M. J., Beeson, K. W., & Parilov, E. (2017) · Cancers · doi:10.3390/cancers9020012 · Cited by 192 · see citing works
X-Ray-Induced Nanoparticle-Based Photodynamic Therapy of Cancer
Zou, X., Yao, M., Ma, L., Hossu, M., Han, X., Juzenas, P., & Chen, W. (2014) · Nanomedicine · doi:10.2217/nnm.13.198 · Cited by 184 · see citing works
New Technology for Deep Light Distribution in Tissue for Phototherapy
Chen, J., Keltner, L., Christophersen, J., Zheng, F., Krouse, M., Singhal, A. K., & Wang, S.-S. (2002) · The Cancer Journal · doi:10.1097/00130404-200203000-00009 · Cited by 172 · see citing works
Photodynamic therapy using meso tetra hydroxy phenyl chlorin (mTHPC) in early prostate cancer
Moore, C. M., Nathan, T. R., Lees, W. R., et al. (2006) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20275 · Cited by 169 · see citing works
Clinical PD/PDT in North America: An historical review
Allison, R. R., Mota, H., & Sibata, C. (2004) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/s1572-1000(04)00084-5 · Cited by 169 · see citing works
Fluence rate effects in photodynamic therapy of multicell tumor spheroids.
Foster, T. H., Hartley, D. F., Nichols, M. G., & Hilf, R. (1993) · PubMed · Cited by 157 · see citing works
Photodynamic therapy with verteporfin (Visudyne): impact on ophthalmology and visual sciences.
Bressler, N. M., & Bressler, S. B. (2000) · PubMed · Cited by 152 · see citing works
HEP computing : where are we now? - open questions for the CHEP'91 conference
Thresher, J. J. (1992) · CERN Document Server (European Organization for Nuclear Research) · Cited by 150 · see citing works
Photodynamic Therapy (PDT) in the Treatment of Patients with Resistant Superficial Bladder Cancer: A Long Term Experience
Nseyo, U. O., DeHaven, J. I., Dougherty, T. J., Potter, W. R., MERRILL, D. L., Lundahl, S. L., & Lamm, D. L. (1998) · Journal of Clinical Laser Medicine & Surgery · doi:10.1089/clm.1998.16.61 · Cited by 150 · see citing works
Effect of photosensitizer concentration in tissue on the penetration depth of photoactivating light
Wilson, B. C., Patterson, M. S., & Burns, D. M. (1986) · Lasers in Medical Science · doi:10.1007/bf02032418 · Cited by 150 · see citing works
Radical Pleurectomy and Intraoperative Photodynamic Therapy for Malignant Pleural Mesothelioma
Friedberg, J. S., Culligan, M. J., Mick, R., et al. (2012) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2012.02.009 · Cited by 148 · see citing works
Photodynamic therapy for nonmelanoma skin cancersCurrent review and update
Zeitouni, N. C. (2003) · Molecular Immunology · doi:10.1016/s0161-5890(03)00083-x · Cited by 147 · see citing works
Photodynamic Therapy of Non–Small Cell Lung Cancer. Narrative Review and Future Directions
Shafirstein, G., Battoo, A., Harris, K. N., Baumann, H., Gollnick, S. O., Lindenmann, J., & Nwogu, C. E. (2015) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201509-650fr · Cited by 147 · see citing works
Photodynamic Therapy for Malignant Brain Tumors
Akimoto, J. (2016) · Neurologia medico-chirurgica · doi:10.2176/nmc.ra.2015-0296 · Cited by 141 · see citing works
Explicit dosimetry for photodynamic therapy: macroscopic singlet oxygen modeling
Wang, K. K., Finlay, J. C., Busch, T. M., et al. (2010) · Journal of Biophotonics · doi:10.1002/jbio.200900101 · Cited by 140 · see citing works
Photodynamic therapy of brain tumors—A work in progress
Müller, P. J., & Wilson, B. C. (2006) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20338 · Cited by 137 · see citing works
Methylene blue‐mediated photodynamic therapy: A possible alternative treatment for oral lichen planus
Aghahosseini, F., Arbabi‐Kalati, F., Fashtami, L. A., Djavid, G. E., Fateh, M., & Beitollahi, J. M. (2006) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20278 · Cited by 129 · see citing works
Photodynamic therapy with BF-200 ALA for the treatment of actinic keratosis: results of a prospective, randomized, double-blind, placebo-controlled phase III study
Szeimies, R., Radny, P., Sebastian, M., Borrosch, F., Dirschka, T., Krähn‐Senftleben, G., Reich, K., Pabst, G., Voss, D., Foguet, M., et al. (2010) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2010.09873.x · Cited by 128 · see citing works
Revisiting photodynamic therapy dosimetry: reductionist & surrogate approaches to facilitate clinical success
Pogue, B. W., Elliott, J. T., Kanick, S. C., Davis, S. C., Samkoe, K. S., Maytin, E. V., Pereira, S. P., & Hasan, T. G. (2016) · Physics in Medicine and Biology · doi:10.1088/0031-9155/61/7/r57 · Cited by 121 · see citing works
Cerenkov emission induced by external beam radiation stimulates molecular fluorescence
Axelsson, J., Davis, S. C., Gladstone, D. J., & Pogue, B. W. (2011) · Medical Physics · doi:10.1118/1.3592646 · Cited by 118 · see citing works
Photodynamic therapy (PDT) using topically applied δ‐aminolevulinic acid (ALA) for the treatment of oral leukoplakia
Sieroń, A., Adamek, M., Kawczyk‐Krupka, A., et al. (2003) · Journal of Oral Pathology and Medicine · doi:10.1034/j.1600-0714.2003.00068.x · Cited by 116 · see citing works
Phase II Trial of Debulking Surgery and Photodynamic Therapy for Disseminated Intraperitoneal Tumors
Hendren, S. K., Hahn, S. M., Spitz, F. R., et al. (2001) · Annals of Surgical Oncology · doi:10.1007/s10434-001-0065-x · Cited by 114 · see citing works
Photonic textiles for pulse oximetry
Rothmaier, M., Selm, B., Spichtig, S., Haensse, D., & Wolf, M. (2008) · Optics Express · doi:10.1364/oe.16.012973 · Cited by 112 · see citing works
Role of various nanoparticles in photodynamic therapy and detection methods of singlet oxygen
Krajczewski, J., Rucińska, K., Townley, H. E., & Kudelski, A. (2019) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2019.03.016 · Cited by 112 · see citing works
Successful treatment of oral verrucous hyperplasia and oral leukoplakia with topical 5-aminolevulinic acid-mediated photodynamic therapy
Chen, H., Yu, C.-H., Tu, P.-C., Yeh, C.-Y., Tsai, T., & Chiang, C. (2005) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20214 · Cited by 110 · see citing works
Practical approach to the use of daylight photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: a European consensus
Morton, C. A., Wulf, H. C., Szeimies, R., et al. (2015) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.12974 · Cited by 107 · see citing works
On the in vivo photochemical rate parameters for PDT reactive oxygen species modeling
Kim, M. M., Ghogare, A. A., Greer, A., & Zhu, T. C. (2017) · Physics in Medicine and Biology · doi:10.1088/1361-6560/62/5/r1 · Cited by 102 · see citing works
Self-citation
Stereotactic Intratumoral Photodynamic Therapy for Recurrent Malignant Brain Tumors
Powers, S. K., Cush, S., Walstad, D. L., & Kwock, L. (1991) · Neurosurgery · doi:10.1097/00006123-199111000-00008 · Cited by 94 · see citing works
Low-cost photodynamic therapy devices for global health settings: Characterization of battery-powered LED performance and smartphone imaging in 3D tumor models
Hempstead, J., Jones, D. P., Ziouche, A., Cramer, G. M., Rizvi, I., Arnason, S. B., Hasan, T. G., & Celli, J. P. (2015) · Scientific Reports · doi:10.1038/srep10093 · Cited by 94 · see citing works
Photodynamic therapy with verteporfin in age‐related macular degeneration: a systematic review of efficacy, safety, treatment modifications and pharmacoeconomic properties
Cruess, A. F., Zlateva, G., Pleil, A. M., & Wirostko, B. M. (2008) · Acta Ophthalmologica · doi:10.1111/j.1755-3768.2008.01218.x · Cited by 91 · see citing works
A new mathematical approach to the diffusion approximation theory for selective photothermolysis modeling and its implication in laser treatment of port‐wine stains
Shafirstein, G., Bäumler, W., Lapidoth, M., et al. (2004) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20028 · Cited by 91 · see citing works
Whole bladder photodynamic therapy with 5-aminolevulinic acid using a white light source
Waidelich, R. M., Beyer, W., Kn�chel, R., Stepp, H. G., Baumgärtner, R., Schrder, J., Hofstetter, A. G., & Kriegmair, M. (2003) · Urology · doi:10.1016/s0090-4295(02)02164-7 · Cited by 91 · see citing works
Endobronchial photodynamic therapy for lung cancer
Loewen, G., Pandey, R. K., Bellnier, D. A., Henderson, B. W., & Dougherty, T. J. (2006) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20354 · Cited by 90 · see citing works
Photodynamic Therapy of oral dysplasia with topical 5‐aminolevulinic acid and light‐emitting diode array
Tsai, J., Chiang, C., Chen, H., Huang, S. B., Wang, C. W., Lee, M. I., Hsu, Y., Chen, C., & Tsai, T. (2004) · Lasers in Surgery and Medicine · doi:10.1002/lsm.10250 · Cited by 90 · see citing works
Photodynamic therapy of cervical intraepithelial neoplasia with hexaminolevulinate
Soergel, P., Wang, X., Stepp, H. G., et al. (2008) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20686 · Cited by 88 · see citing works
A Review of Photodynamic Therapy for Neoplasms of the Head and Neck
Civantos, F., Karakullukçu, B., Biel, M. A., et al. (2018) · Advances in Therapy · doi:10.1007/s12325-018-0659-3 · Cited by 87 · see citing works
mTHPC-mediated Photodynamic Diagnosis of Malignant Brain Tumors¶
Zimmermann, A., Ritsch‐Marte, M., & Kostron, H. (2001) · Photochemistry and Photobiology · doi:10.1562/0031-8655(2001)0740611mmpdom2.0.co2 · Cited by 83 · see citing works
Photodynamic therapy of malignant tumors.
McCaughan, J. S. (1988) · PubMed · Cited by 83 · see citing works
New design of textile light diffusers for photodynamic therapy
Cochrane, C., Mordon, S. R., Lesage, J. C., et al. (2012) · Materials Science and Engineering C · doi:10.1016/j.msec.2012.12.007 · Cited by 81 · see citing works
Preliminary evaluation of two fluorescence imaging methods for the detection and the delineation of basal cell carcinomas of the skin
Andersson‐Engels, S., Canti, G. L., Cubeddu, R., Eker, C., af Klinteberg, C., Pifferi, A., Svanberg, K., Svanberg, S. R., Taroni, P., Valentini, G., et al. (2000) · Lasers in Surgery and Medicine · doi:10.1002/(sici)1096-9101(2000)26:1 · Cited by 80 · see citing works
Photodynamic Therapy for Barrett’s Esophagus
Panjehpour, M., & Overholt, B. F. (2009) · Frontiers of gastrointestinal research · doi:10.1159/000258356 · Cited by 80 · see citing works
Photodynamic Therapy – A Non-invasive Treatment Modality for Precancerous Lesions
Maloth, K. N., Velpula, N., Kodangal, S., et al. (2016) · Journal of lasers in medical sciences · doi:10.15171/jlms.2016.07 · Cited by 80 · see citing works
Proliferation of renal cell carcinoma assessed by fixation-resistant polyclonal Ki-67 antibody labeling. Correlation with clinical outcome
Delahunt, B., Bethwaite, P. B., Thornton, A., & Ribas, J. L. (1995) · Cancer · doi:10.1002/1097-0142(19950601)75:11 · Cited by 79 · see citing works
Successful treatment of oral verrucous hyperplasia with topical 5-aminolevulinic acid-mediated photodynamic therapy
Chen, H. (2004) · Oral Oncology · doi:10.1016/j.oraloncology.2003.12.010 · Cited by 77 · see citing works
Photodynamic Therapy for Barrett's Esophagus and Esophageal Carcinoma
Qumseya, B. J., David, W., & Wolfsen, H. C. (2013) · Clinical Endoscopy · doi:10.5946/ce.2013.46.1.30 · Cited by 75 · see citing works
Photodynamic therapy: A hot topic in dermato-oncology (Review)
Tampa, M., Sarbu, M.-I., Matei, C., Mitran, C.-I., Mitran, M.-I., Caruntu, C., Constantin, C., Neagu, M., & Georgescu, S.-R. (2019) · Oncology Letters · doi:10.3892/ol.2019.9939 · Cited by 72 · see citing works
The application and challenges of clinical PD–PDT in the head and neck region: A short review
Bredell, M., Besic, E., Maake, C., et al. (2010) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2010.07.002 · Cited by 71 · see citing works
Eradication of Dysplastic Barrett’s Oesophagus Using Photodynamic Therapy: Long-Term Follow-Up
Ackroyd, R., Kelty, C., Brown, N. J., et al. (2003) · Endoscopy · doi:10.1055/s-2003-39676 · Cited by 70 · see citing works
Photodynamic therapy in the treatment of oral leukoplakia: A systematic review
Li, Y., Wang, B., Zheng, S., et al. (2018) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2018.10.023 · Cited by 70 · see citing works
Comparison of clinical outcomes of oral erythroleukoplakia treated with photodynamic therapy using either light‐emitting diode or laser light
Yu, C., Lin, H., Chen, H., Yang, H., Wang, Y., & Chiang, C. (2009) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20841 · Cited by 69 · see citing works
Interstitial Fluorescence Spectroscopy in the Human Prostate During Motexafin Lutetium‐Mediated Photodynamic Therapy
Finlay, J. C., Zhu, T. C., Dimofte, A., Stripp, D. C. H., Malkowicz, S. B., Busch, T. M., & Hahn, S. M. (2006) · Photochemistry and Photobiology · doi:10.1562/2005-10-04-ra-711 · Cited by 69 · see citing works
Adjuvant Intraoperative Photodynamic Therapy in Head and Neck Cancer
Rigual, N., Shafirstein, G., Frustino, J. L., Seshadri, M., Cooper, M., Wilding, G. E., Sullivan, M. A., & Henderson, B. W. (2013) · JAMA Otolaryngology–Head & Neck Surgery · doi:10.1001/jamaoto.2013.3387 · Cited by 67 · see citing works
Clinical application of photodynamic diagnosis and photodynamic therapy for gynecologic malignant diseases: A review
Matoba, Y., Banno, K., Kisu, I., & Aoki, D. (2018) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2018.08.014 · Cited by 66 · see citing works
Stereotactic Intratumoral Photodynamic Therapy for Recurrent Malignant Brain Tumors
Powers, S. K., Cush, S., Walstad, D. L., et al. (1991) · Neurosurgery · doi:10.1227/00006123-199111000-00008 · Cited by 66 · see citing works
mTHPC mediated photodynamic therapy (PDT) of squamous cell carcinoma in the head and neck: A systematic review
de Visscher, S. A. H. J., Dijkstra, P. U., Tan, I. B., et al. (2012) · Oral Oncology · doi:10.1016/j.oraloncology.2012.09.011 · Cited by 63 · see citing works
In-vivo singlet oxygen threshold doses for PDT
Zhu, T. C., Kim, M. M., Liang, X., et al. (2015) · Photonics and Lasers in Medicine · doi:10.1515/plm-2014-0037 · Cited by 62 · see citing works
Self-citation
A multicenter Phase I safety study of intratumoral photoactivation of talaporfin sodium in patients with refractory solid tumors
Lustig, R. A., Vogl, T. J., Fromm, D., et al. (2003) · Cancer · doi:10.1002/cncr.11708 · Cited by 61 · see citing works
mTHPC-mediated Photodynamic Therapy of Early Stage Oral Squamous Cell Carcinoma: A Comparison to Surgical Treatment
de Visscher, S. A. H. J., Melchers, L. J., Dijkstra, P. U., et al. (2013) · Annals of Surgical Oncology · doi:10.1245/s10434-013-3006-6 · Cited by 61 · see citing works
Macroscopic modeling of the singlet oxygen production during PDT
Zhu, T. C., Finlay, J. C., Zhou, X. R., et al. (2007) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.701387 · Cited by 61 · see citing works
Modeling of a Type II Photofrin‐mediated Photodynamic Therapy Process in a Heterogeneous Tissue Phantom
Hu, X., Feng, Y., Lu, J. Q., et al. (2005) · Photochemistry and Photobiology · doi:10.1562/2005-05-04-ra-513 · Cited by 61 · see citing works
Light-emitting Diodes as a Light Source for Intraoperative Photodynamic Therapy
Schmidt, M. H., Bajic, D. M., Reichert, K. W., et al. (1996) · Neurosurgery · doi:10.1097/00006123-199603000-00025 · Cited by 59 · see citing works
Photodynamic therapy (PDT) using HPPH for the treatment of precancerous lesions associated with barrett's esophagus
Nava, H., Allamaneni, S. S. R., Dougherty, T. J., et al. (2011) · Lasers in Surgery and Medicine · doi:10.1002/lsm.21112 · Cited by 58 · see citing works
Photodynamic therapy for esophageal cancer.
Yano, T., Hatogai, K., Morimoto, H., et al. (2014) · PubMed · doi:10.3978/j.issn.2305-5839.2014.03.01 · Cited by 57 · see citing works
Photodynamic Diagnosis of Prostate Cancer Using 5-Aminolevulinic Acid—First Clinical Experiences
Zaak, D., Sroka, R. C., Khoder, W. Y., Adam, C., Tritschler, S., Karl, A., Reich, O. M., Knuechel, R., Baumgartner, R., Derya Tilki, A., et al. (2008) · Urology · doi:10.1016/j.urology.2007.12.086 · Cited by 57 · see citing works
Photodynamic Therapy for Barrett’s Esophagus
Overholt, B. F., & Panjehpour, M. (1997) · Gastrointestinal Endoscopy Clinics of North America · doi:10.1016/s1052-5157(18)30308-8 · Cited by 54 · see citing works
Novel flexible light diffuser and irradiation properties for photodynamic therapy
Selm, B., Rothmaier, M., Camenzind, M., Khan, T., & Walt, H. (2007) · Journal of Biomedical Optics · doi:10.1117/1.2749737 · Cited by 53 · see citing works
Treatment outcome of Photofrin-based photodynamic therapy for T1 and T2 oral squamous cell carcinoma and dysplasia
Ikeda, H., Tobita, T., Ohba, S., et al. (2013) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2013.01.006 · Cited by 53 · see citing works
mTHPC mediated interstitial photodynamic therapy of recurrent nonmetastatic base of tongue cancers: Development of a new method
Karakullukçu, B., Nyst, H. J., van Veen, R. L. P., et al. (2012) · Head & Neck · doi:10.1002/hed.21969 · Cited by 53 · see citing works
In situ light dosimetry during whole bladder wall photodynamic therapy: clinical results and experimental verification
Marijnissen, J. P. A., Star, W., Zandt, R. I. ‘., D’Hallewin, M., & Baert, L. V. (1993) · Physics in Medicine and Biology · doi:10.1088/0031-9155/38/5/001 · Cited by 52 · see citing works
Primary Clinical Evaluation of Photodynamic Therapy With Oral Leukoplakia in Chinese Patients
Han, Y., Xu, S., Jin, J., et al. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2018.01911 · Cited by 52 · see citing works
Photodynamic Therapy: Light Delivery and Dosage for Second‐Generation Photosensitizers
Wilson, B. C. (2007) · Novartis Foundation symposium · doi:10.1002/9780470513842.ch5 · Cited by 51 · see citing works
Efficacy of adjunctive photodynamic therapy on the clinical periodontal, HbA1c and advanced glycation end product levels among mild to moderate chronic periodontal disease patients with type 2 diabetes mellitus: A randomized controlled clinical trial
Mirza, S., Khan, A. A., Kheraif, A. A. A., Khan, S. Z., & Shafqat, S. S. (2019) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2019.08.003 · Cited by 49 · see citing works
PHOTODYNAMIC THERAPY WITH VERTEPORFIN FOR CHOROIDAL NEOVASCULARIZATION CAUSED BY AGE-RELATED MACULAR DEGENERATION
Miller, J. W., Schmidt-Erfurth, U. M., & Sickenberg, M. (2000) · Evidence-Based Eye Care · doi:10.1097/00132578-200001000-00016 · Cited by 48 · see citing works
Brain photodiagnosis (PD), fluorescence guided resection (FGR) and photodynamic therapy (PDT): Past, present and future
Eljamel, S. (2008) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2008.01.006 · Cited by 47 · see citing works
PHOTOFRIN‐mediated photodynamic therapy for treatment of early stage (Tis‐T2N0M0) SqCCa of oral cavity and oropharynx
Schweitzer, V. G., & Somers, M. L. (2010) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20881 · Cited by 47 · see citing works
Luciferase–Rose Bengal conjugates for singlet oxygen generation by bioluminescence resonance energy transfer
Kim, S., Jo, H., Jeon, M., et al. (2017) · Chemical Communications · doi:10.1039/c7cc00041c · Cited by 46 · see citing works
PDT dose dosimetry for Photofrin-mediated pleural photodynamic therapy (pPDT)
Ong, Y. H., Kim, M. M., Finlay, J. C., Dimofte, A., Singhal, S. K., GLATSTEIN, E. J., Cengel, K. A., & Zhu, T. C. (2017) · Physics in Medicine and Biology · doi:10.1088/1361-6560/aa9874 · Cited by 46 · see citing works
Self-citation
Treatment of oral leukoplakia with photodynamic therapy: A pilot study
Selvam, N. P., Sadaksharam, J., Ganesan, S., et al. (2015) · Journal of Cancer Research and Therapeutics · doi:10.4103/0973-1482.147703 · Cited by 43 · see citing works
Photodynamic therapy for Bowen’s Disease (squamous cell carcinoma in situ) current review and update
O’Connell, K. A., Okhovat, J., & Zeitouni, N. C. (2018) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2018.09.009 · Cited by 41 · see citing works
Proton-dynamic therapy following photosensitiser activation by accelerated protons demonstrated through fluorescence and singlet oxygen production
Grigalavicius, M., Mastrangelopoulou, M., Berg, K., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12042-7 · Cited by 40 · see citing works
Optical super-resolution and periodical focusing effects by dielectric microspheres
Darafsheh, A. (2013) · NC Digital Online Collection of Knowledge and Scholarship (The University of North Carolina at Greensboro) · Cited by 39 · see citing works
Self-citation
Photodynamic therapy for oral potentially malignant disorders
Jin, X., Xu, H. Y., Deng, J., Dan, H., Ji, P., Chen, Q., & Zeng, X. Y. (2019) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2019.08.005 · Cited by 39 · see citing works
A new finite element approach for near real‐time simulation of light propagation in locally advanced head and neck tumors
Oakley, E., Wrazen, B., Bellnier, D. A., et al. (2015) · Lasers in Surgery and Medicine · doi:10.1002/lsm.22313 · Cited by 37 · see citing works
Performance of a dedicated light delivery and dosimetry device for photodynamic therapy of nasopharyngeal carcinoma: Phantom and volunteer experiments
Nyst, H. J., van Veen, R. L. P., Tan, I. B., et al. (2007) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20536 · Cited by 36 · see citing works
Successful photodynamic therapy with topical 5-aminolevulinic acid for five cases of cervical intraepithelial neoplasia
Wang, J., Xu, J., Chen, J., He, Q., Li, X., Huang, X.-M., Ding, G., & Xu, S. (2009) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-009-1335-2 · Cited by 36 · see citing works
Lesion oxygenation associates with clinical outcomes in premalignant and early stage head and neck tumors treated on a phase 1 trial of photodynamic therapy
Ahn, P. H., Finlay, J. C., Gallagher‐Colombo, S. M., Quon, H., O’Malley, B. W., Weinstein, G. S., Chalian, A. A., Malloy, K. M., Sollecito, T. P., Greenberg, M. S., et al. (2017) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2017.10.015 · Cited by 35 · see citing works
Photodynamic therapy for cholangiocarcinoma using low dose mTHPC (Foscan®)
Kniebühler, G., Pongratz, T., Betz, C. S., et al. (2013) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2012.12.005 · Cited by 34 · see citing works
A compact fiber‐optic probe‐based singlet oxygen luminescence detection system
Gemmell, N. R., McCarthy, A., Kim, M. M., et al. (2016) · Journal of Biophotonics · doi:10.1002/jbio.201600078 · Cited by 33 · see citing works
Self-citation
Photodynamic therapy for gynecological diseases and breast cancer.
Shishkova, N., Kuznetsova, O. M., & Berezov, T. T. (2012) · PubMed · doi:10.3969/j.issn.2095-3941.2012.01.002 · Cited by 32 · see citing works
Evaluation of singlet oxygen explicit dosimetry for predicting treatment outcomes of benzoporphyrin derivative monoacid ring A-mediated photodynamic therapy
Kim, M. M., Penjweini, R., & Zhu, T. C. (2017) · Journal of Biomedical Optics · doi:10.1117/1.jbo.22.2.028002 · Cited by 32 · see citing works
Self-citation
Strategies of airway management for head and neck photo‐dynamic therapy
Story, W., Sultan, A. A., Bottini, G. B., et al. (2013) · Lasers in Surgery and Medicine · doi:10.1002/lsm.22149 · Cited by 31 · see citing works
A Comparison of Dose Metrics to Predict Local Tumor Control for Photofrin‐mediated Photodynamic Therapy
Qiu, H., Kim, M. M., Penjweini, R., Finlay, J. C., Busch, T. M., Wang, T., Guo, W., Cengel, K. A., Simone, C. B., GLATSTEIN, E. J., et al. (2017) · Photochemistry and Photobiology · doi:10.1111/php.12719 · Cited by 31 · see citing works
Self-citation
A dedicated applicator for light delivery and monitoring of PDT of intra-anal intraepithelial neoplasia
Kruijt, B., van der Snoek, E. M., Sterenborg, H. J. C. M., Amelink, A., & Robinson, D. J. (2010) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2010.01.006 · Cited by 29 · see citing works
Photodiagnosis for cutaneous malignancy: A brief clinical and technical review
Allison, R. R., & Sibata, C. H. (2008) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2009.01.002 · Cited by 29 · see citing works
A Novel Prospective Study Assessing the Combination of Photodynamic Therapy and Proton Radiation Therapy: Safety and Outcomes When Treating Malignant Pleural Mesothelioma
Rice, S. R., Li, Y. R., Busch, T. M., et al. (2018) · Photochemistry and Photobiology · doi:10.1111/php.13065 · Cited by 28 · see citing works
Experimental photodynamic therapy for malignant pleural mesothelioma with pegylated m THPC
Krueger, T., Altermatt, H. J., Mettler, D., et al. (2003) · Lasers in Surgery and Medicine · doi:10.1002/lsm.10113 · Cited by 27 · see citing works
An IR navigation system for pleural PDT
Zhu, T. C., Liang, X., Kim, M. M., et al. (2015) · Frontiers in Physics · doi:10.3389/fphy.2015.00009 · Cited by 26 · see citing works
Self-citation
PDT dose dosimeter for pleural photodynamic therapy
Kim, M. M., Darafsheh, A., Ahmad, M., Finlay, J. C., & Zhu, T. C. (2016) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.2213401 · Cited by 25 · see citing works
Self-citation
Multifunctional nanoparticles for trimodal photodynamic therapy-mediated photothermal and chemotherapeutic effects
Vivek, R., Babu, V. N., Rejeeth, C., Alok, S., Ponraj, T., Vasanthakumar, A., & Kannan, S. (2018) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2018.06.025 · Cited by 25 · see citing works
Photodynamic therapy of oral leukoplakia and oral lichen planus using methylene blue: A pilot study
Prasanna, S. W., Ingle, E., Aruna, P. R., et al. (2014) · Journal of Innovative Optical Health Sciences · doi:10.1142/s1793545815400052 · Cited by 24 · see citing works
Comparison of Blue and White Lamp Light with Sunlight for Daylight‐Mediated, 5‐ ALA Photodynamic Therapy, in vivo
Marra, K. A., LaRochelle, E. P. M., Chapman, M. S., Hoopes, P. J., Lukovits, K., Maytin, E. V., Hasan, T. G., & Pogue, B. W. (2018) · Photochemistry and Photobiology · doi:10.1111/php.12923 · Cited by 24 · see citing works
Daylight versus conventional photodynamic therapy for the treatment of actinic keratosis: A meta-analysis of randomized controlled trials
Mei, X., Wang, L., Zhang, R., et al. (2018) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2018.11.005 · Cited by 24 · see citing works
mTHPC mediated, systemic photodynamic therapy (PDT) for nonmelanoma skin cancers: Case and literature review
Horlings, R. K., Terra, J. B., & Witjes, M. J. H. (2015) · Lasers in Surgery and Medicine · doi:10.1002/lsm.22429 · Cited by 23 · see citing works
Listeria innocua Dps as a nanoplatform for bioluminescence based photodynamic therapy utilizing Gaussia princeps luciferase and zinc protoporphyrin IX
Al-Ani, A. W., Zhang, L., Ferreira, L., et al. (2019) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2019.04.008 · Cited by 23 · see citing works
Evaluation of Light Fluence Distribution Using an IR Navigation System for HPPH‐mediated Pleural Photodynamic Therapy (pPDT)
Zhu, T. C., Ong, Y. H., Kim, M. M., Liang, X., Finlay, J. C., Dimofte, A., Simone, C. B., Friedberg, J. S., Busch, T. M., GLATSTEIN, E. J., et al. (2019) · Photochemistry and Photobiology · doi:10.1111/php.13166 · Cited by 21 · see citing works
Self-citation
Characterization of rare-earth-doped nanophosphors for photodynamic therapy excited by clinical ionizing radiation beams
Darafsheh, A., Najmr, S., Paik, T., et al. (2015) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.2079373 · Cited by 20 · see citing works
Self-citation
Advantages of laserphyrin compared with photofrin in photodynamic therapy for bile duct carcinoma
Nonaka, T., Nanashima, A., Nonaka, M., et al. (2011) · Journal of Hepato-Biliary-Pancreatic Sciences · doi:10.1007/s00534-011-0377-6 · Cited by 19 · see citing works
Photodynamic therapy for mesothelioma
Hahn, S. M., Smith, R. P., & Friedberg, J. S. (2001) · Current Treatment Options in Oncology · doi:10.1007/s11864-001-0042-4 · Cited by 19 · see citing works
Towards conformal light delivery using tailored cylindrical diffusers: attainable light dose distributions
Rendon, A., Weersink, R., & Lilge, L. D. (2006) · Physics in Medicine and Biology · doi:10.1088/0031-9155/51/23/001 · Cited by 18 · see citing works
A light blanket for intraoperative photodynamic therapy
Hu, Y., Wang, K., & Zhu, T. C. (2009) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.823064 · Cited by 18 · see citing works
Dosimetry study of PHOTOFRIN-mediated photodynamic therapy in a mouse tumor model
Qiu, H., Kim, M. M., Penjweini, R., et al. (2016) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.2211169 · Cited by 17 · see citing works
Self-citation
Explicit macroscopic singlet oxygen modeling for benzoporphyrin derivative monoacid ring A (BPD)-mediated photodynamic therapy
Kim, M. M., Penjweini, R., Liang, X., & Zhu, T. C. (2016) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2016.09.031 · Cited by 17 · see citing works
Self-citation
Transoral robotic photodynamic therapy for the oropharynx
Quon, H., Finlay, J. C., Cengel, K. A., et al. (2011) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2010.12.005 · Cited by 15 · see citing works
An IR navigation system for real-time treatment guidance of pleural PDT
Zhu, T. C., Liang, X., Chang, C., et al. (2011) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.875635 · Cited by 15 · see citing works
A novel homogeneous irradiation fiber probe for whole bladder wall photodynamic therapy
Miyazaki, K., Morimoto, Y., Nishiyama, N., et al. (2012) · Lasers in Surgery and Medicine · doi:10.1002/lsm.22010 · Cited by 15 · see citing works
Light Patch: Preliminary Report of a Novel Form of Blue Light Delivery for the Treatment of Actinic Keratosis
Zelickson, B. D., Counters, J., Coles, C. M., & Selim, M. M. (2006) · Dermatologic Surgery · doi:10.1111/j.1524-4725.2005.31094 · Cited by 15 · see citing works
Targeted laryngeal photodynamic therapy with a balloon diffusing light source
Grossman, C. E., Zhu, T. C., Finlay, J. C., et al. (2010) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2010.06.001 · Cited by 15 · see citing works
Recovery of layered tissue optical properties from spatial frequency-domain spectroscopy and a deterministic radiative transport solver
Horan, S. T., Gardner, A. R., Saager, R. B., Durkin, A. J., & Venugopalan, V. (2018) · Journal of Biomedical Optics · doi:10.1117/1.jbo.24.7.071607 · Cited by 14 · see citing works
Light Sources, Drugs, and Dosimetry
Finlay, J. C., & Darafsheh, A. (2016) · Springer eBooks · doi:10.1007/978-1-4939-1758-7_19 · Cited by 13 · see citing works
Self-citation
Weather‐informed Light–tissue Model–Based Dose Planning for Indoor Daylight Photodynamic Therapy
LaRochelle, E. P. M., Chapman, M. S., Maytin, E. V., et al. (2019) · Photochemistry and Photobiology · doi:10.1111/php.13170 · Cited by 13 · see citing works
Topical 5-aminolevulinic acid photodynamic therapy for laryngeal papillomatosistosis treatment
Liang, F., Han, P., Chen, R., et al. (2019) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2019.08.021 · Cited by 12 · see citing works
Absolute calibration of optical power for PDT: Report of AAPM TG140
Zhu, T. C., Bonnerup, C., Colussi, V., Dowell, M. L., Finlay, J. C., Lilge, L. D., Slowey, T. W., & Sibata, C. H. (2013) · Medical Physics · doi:10.1118/1.4813897 · Cited by 11 · see citing works
Tumor growth pattern and thymidine phosphorylase expression are related with the risk of hematogenous metastasis in patients with Astler Coller B1/B2 colorectal carcinoma
van Halteren, H. K., Peters, H. M., van Krieken, J. H., Coebergh, J. W. W., Roumen, R. M. H., van der Worp, E., Wagener, J. T., & Vreugdenhil, G. (2001) · Cancer · doi:10.1002/1097-0142(20010501)91:9 · Cited by 9 · see citing works
Light dosimetry measurements during ALA-PDT of Barrett's oesophagus
Stringer, M. R., Kelty, C., Ackroyd, R., et al. (2006) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/s1572-1000(05)00155-9 · Cited by 8 · see citing works
mTHPC pharmacokinetics following topical administration
Johansson, A., Svensson, J., Andersson‐Engels, S., Bendsøe, N., Svanberg, K., Bigio, I. J., Alexandratou, E., Kyriazi, M., Yova, D. M., Gräfe, S., et al. (2006) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.647602 · Cited by 7 · see citing works
Photodynamic Therapy of Diseases of the Head and Neck
Biel, M. A. (2008) · Cited by 6 · see citing works
Photodynamic Therapy for Gynecological Diseases and Breast Cancer
Shishkova, N., Kuznetsova, O. M., & Berezov, T. T. (2012) · DOAJ (DOAJ: Directory of Open Access Journals) · doi:10.7497/j.issn.2095-3941.2012.01.002 · Cited by 6 · see citing works
Physics of Photodynamic Therapy
Madsen, S. J. (2016) · Springer eBooks · doi:10.1007/978-1-4939-1758-7_18 · Cited by 3 · see citing works

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Research works printed but not linked: 6

Shafirstein, G., A. Battoo, K. Harris, H. Baumann, S. O. Gollnick, J. Lindenmann and C. E. Nwogu (2016) Photodynamic therapy of non-small cell lung cancer. Ann. Am. Thorac. Soc. 13(2), 265-275.
Dougherty, T. J., C. J. Gomer, B. W. Henderson, G. Jori, D. Kes- sel, M. Korbelik, J. Moan and Q. Peng (1998) Photodynamic ther- apy. J. Natl. Cancer Inst. 90(12), 889-905.
Hecht, E. (2017) Optics. 5th edn. London, England: Pearson Educa- tion Inc.
Sch€ afer, F. P. (1990) Dye Lasers. Springer, Berlin.
Dwyer, P. J., W. M. White, R. L. Fabian and R. R. Anderson (2000) Optical integrating balloon device for photodynamic therapy. Lasers Surg. Med. 26(1), 58-66.
Braichotte, D. R., G. A. Wagnieres, R. Bays, P. Monnier and H. E. D. van Bergh (1995) Clinical pharmacokinetic studies of photofrin by fluorescence spectroscopy in the oral cavity, the esophagus, and the bronchi. Cancer 75(11), 2768-2778.

Sorted by citations

Depth Penetration of Light into Skin as a Function of Wavelength from 200 to 1000 nm
Finlayson, L., Barnard, I. R. M., McMillan, L., Ibbotson, S. H., Brown, C. T. A., Eadie, E., & Wood, K. (2022) · Photochemistry and Photobiology · doi:10.1111/php.13550 · Cited by 302 · see citing works
Effect of skin color on optical properties and the implications for medical optical technologies: a review
Setchfield, K., Gorman, A., Simpson, A. H. R. W., Somekh, M. G., & Wright, A. J. (2024) · Journal of Biomedical Optics · doi:10.1117/1.jbo.29.1.010901 · Cited by 72 · see citing works

Authors: Kim, M. M., & Darafsheh, A.
Affiliations: University of Pennsylvania (US)
Washington University in St. Louis (US)
Corresponding author: Darafsheh, Arash
ORCID: Kim, Michele M.
Darafsheh, Arash
Venue: Photochemistry and Photobiology
Publisher: Wiley
Published: 2020-03
Volume: 96
Issue: 2
Pages: 280-294
ISSN: 0031-8655 (ISSN-L)
1751-1097
DOI: 10.1111/php.13219
OpenAlex: W3003160777
Cited by: 454
References: 185
Citations by year: 2026: 50 · 2025: 92 · 2024: 108 · 2023: 87 · 2022: 62 · 2021: 44 · 2020: 11
FWCI: 7.14
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 16 d)
Locations: Photochemistry and Photobiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
Keywords: photodynamic therapy, light sources, dosimetry, lasers, light-emitting diodes, lamps, photosensitizers, tissue scattering
MeSH terms: Dose-Response Relationship, Drug, Dose-Response Relationship, Radiation, Humans, Light, Photochemotherapy, Drug Delivery Systems, Photosensitizing Agents

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Light Sources and Dosimetry Techniques for Photodynamic Therapy

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