Cited by 243Food composition and propertiesGut microbiota and healthMicrobial Metabolites in Food Biotechnology

The DOI matches its Crossref record; 75 of the 75 references it cites were found in a registry or an index.

Role of Resistant Starch in Improving Gut Health, Adiposity, and Insulin Resistance

Open access

Keenan, Michael J, Zhou, June, Hegsted, Maren, Pelkman, Christine, Durham, Holiday A, Coulon, Diana B, Martin, Roy J·2015·Advances in Nutrition

DOI 10.3945/an.114.007419PMC PMC4352178

Open this paper in CoChat — free account Open PDF

Abstract

The realization that low-glycemic index diets were formulated using resistant starch led to more than a decade of research on the health effects of resistant starch. Determination of the metabolizable energy of the resistant starch product allowed for the performance of isocaloric studies. Fermentation of resistant starch in rodent studies results in what appears to be a healthier gut, demonstrated by increased amounts of short-chain fatty acids, an apparent positive change in the microbiota, and increased gene expression for gene products involved in normal healthy proliferation and apoptosis of potential cancer cells. Additionally, consumption of resistant starch was associated with reduced abdominal fat and improved insulin sensitivity. Increased serum glucagon-like peptide 1 (GLP-1) likely plays a role in promoting these health benefits. One rodent study that did not use isocaloric diets demonstrated that the use of resistant starch at 8% of the weight of the diet reduced body fat. This appears to be approximately equivalent to the human fiber requirement. In human subjects, insulin sensitivity is increased with the feeding of resistant starch. However, only 1 of several studies reports an increase in serum GLP-1 associated with resistant starch added to the diet. This means that other mechanisms, such as increased intestinal gluconeogenesis or increased adiponectin, may be involved in the promotion of improved insulin sensitivity. Future research may confirm that there will be improved health if human individuals consume the requirement for dietary fiber and a large amount of the fiber is fermentable.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.3945/an.114.007419

Cites

75 of 75 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

AIN-93 Purified Diets for Laboratory Rodents: Final Report of the American Institute of Nutrition Ad Hoc Writing Committee on the Reformulation of the AIN-76A Rodent Diet
Reeves, P. G., Nielsen, F. H., & Fahey, G. C., Jr. (1993) · Journal of Nutrition · doi:10.1093/jn/123.11.1939 · Cited by 8,751
Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
Cani, P. D., Bibiloni, R., Knauf, C., Waget, A., Neyrinck, A. M., Delzenne, N. M., & Burcelin, R. (2008) · Diabetes · doi:10.2337/db07-1403 · Cited by 4,819
Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour
Cryan, J. F., & Dinan, T. G. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3346 · Cited by 4,572
Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides
Topping, D. L., & Clifton, P. M. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.3.1031 · Cited by 3,091
Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits
De Vadder, F., Kovatcheva-Datchary, P., Goncalves, D., Vinera, J., Zitoun, C., Duchampt, A., Bäckhed, F., & Mithieux, G. (2014) · Cell · doi:10.1016/j.cell.2013.12.016 · Cited by 2,200
Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium
Derrien, M., Vaughan, E. E., Plugge, C. M., & de Vos, W. M. (2004) · International Journal of Systematic and Evolutionary Microbiology · doi:10.1099/ijs.0.02873-0 · Cited by 2,094
TNF-R1 Signaling: A Beautiful Pathway
Chen, G., & Goeddel, D. V. (2002) · Science · doi:10.1126/science.1071924 · Cited by 1,930
Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia
Cani, P. D., Neyrinck, A. M., Fava, F., Knauf, C., Burcelin, R., Tuohy, K. M., Gibson, G. R., & Delzenne, N. M. (2007) · Diabetologia · doi:10.1007/s00125-007-0791-0 · Cited by 1,770
Resistant Starch–A Review
Sajilata, M. G., Singhal, R. S., & Kulkarni, P. R. (2006) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/j.1541-4337.2006.tb00076.x · Cited by 1,660
The microbiology of butyrate formation in the human colon
Pryde, S. E., Duncan, S. H., Hold, G. L., Stewart, C. S., & Flint, H. J. (2002) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2002.tb11467.x · Cited by 1,320

Show all 74 references

Sorted by citations

Items 101–200 of 243

Amelioration of obesity in high-fat diet-fed mice by chestnut starch modified by amylosucrase from Deinococcus geothermalis
Lee, E., Lee, B., Shin, D., Lim, M.-Y., Chung, W., Park, C., Baik, M., Nam, Y., & Seo, D. (2017) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2017.09.019 · Cited by 31
High–Resistant Starch, Low-Protein Flour Intervention on Patients With Early Type 2 Diabetic Nephropathy: A Randomized Trial
Meng, Y., Bai, H., Yu, Q., Jin, Y., Zhao, L., Wang, S., Li, Z., Wang, Q., & Chen, L. (2019) · Journal of Renal Nutrition · doi:10.1053/j.jrn.2018.12.005 · Cited by 31
Targeting Glycoproteins as a therapeutic strategy for diabetes mellitus and its complications
Naseri, R., Navabi, S. J., Samimi, Z., Mishra, A. P., Nigam, M., Chandra, H., Olatunde, A., Tijjani, H., Morais‐Urano, R. P., & Farzaei, M. H. (2020) · DARU Journal of Pharmaceutical Sciences · doi:10.1007/s40199-020-00327-y · Cited by 31
Characterization of insoluble dietary fiber from Pleurotus eryngii and evaluation of its effects on obesity-preventing or relieving effects via modulation of gut microbiota
Han, X., Yang, D., Zhang, S., Liu, X., Zhao, Y., Song, C., & Sun, Q. (2022) · Journal of Future Foods · doi:10.1016/j.jfutfo.2022.09.009 · Cited by 29
Stability of starch-proanthocyanidin complexes to in-vitro amylase digestion after hydrothermal processing
Althawab, S. A., Amoako, D. B., Annor, G. A., & Awika, J. M. (2023) · Food Chemistry · doi:10.1016/j.foodchem.2023.136182 · Cited by 28
Lactic acid bacteria–derived γ-linolenic acid metabolites are PPARδ ligands that reduce lipid accumulation in human intestinal organoids
Noguchi, M., Shimizu, M., Lü, P., Takahashi, Y., Yamauchi, Y., Sato, S., Kiyono, H., Kishino, S., Ogawa, J., Nagata, K., et al. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102534 · Cited by 29
The structural properties and resistant digestibility of maize starch-glyceride monostearate complexes
Wang, C., Zhu, Z., Mei, L., Xia, Y., Chen, X., Mustafa, S., & Du, X. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.126141 · Cited by 26
Enzymatic extraction of green banana resistant starch for future food preparation: Structural, physicochemical and functional characterization
Islam, S., Miah, M. A. S., Islam, M. F., Tisa, K. J., & Mondol, M. M. H. (2024) · Future Foods · doi:10.1016/j.fufo.2024.100308 · Cited by 25
Resistant starch wheat increases PYY and decreases GIP but has no effect on self-reported perceptions of satiety
Hughes, R., Horn, W. F., Wen, A., RUST, B. M., Woodhouse, L. R., Newman, J. W. I., & Keim, N. L. (2021) · Appetite · doi:10.1016/j.appet.2021.105802 · Cited by 26
Compositional data analysis as an alternative paradigm for nutritional studies
Leite, M. L. C. (2019) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2019.05.011 · Cited by 25
Effect of resistant starch type 2 on inflammatory mediators: A systematic review and meta-analysis of randomized controlled trials
Haghighatdoost, F., Gholami, A., & Hariri, M. (2020) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2020.102597 · Cited by 24
Nonpharmacologic Strategies to Modulate Nuclear Factor Erythroid 2–related Factor 2 Pathway in Chronic Kidney Disease
Esgalhado, M., Stenvinkel, P., & Mafra, D. (2017) · Journal of Renal Nutrition · doi:10.1053/j.jrn.2017.01.022 · Cited by 24
CRISPR/Cas mediated genome editing in potato: Past achievements and future directions
Tuncel, A., & Qi, Y. (2022) · Plant Science · doi:10.1016/j.plantsci.2022.111474 · Cited by 25
A Comprehensive Review of the Effects of Glycemic Carbohydrates on the Neurocognitive Functions Based on Gut Microenvironment Regulation and Glycemic Fluctuation Control
Jian, Y., Cheng, L., Hong, Y., Li, Z., Li, C., Ban, X., Zhu, L., & Gu, Z. (2023) · Nutrients · doi:10.3390/nu15245080 · Cited by 24
A comprehensive study on core enzymes involved in starch metabolism in the model nutricereal, foxtail millet (Setaria italica L.)
Dhaka, A., Muthamilarasan, M., & Prasad, M. (2020) · Journal of Cereal Science · doi:10.1016/j.jcs.2020.103153 · Cited by 22
Research Progress on Hypoglycemic Mechanisms of Resistant Starch: A Review
Liu, J., Lu, W., Liang, Y., Wang, L., Jin, N., Zhao, H., Fan, B., & Wang, L. (2022) · Molecules · doi:10.3390/molecules27207111 · Cited by 26
Resistant Starch but Not Enzymatically Modified Waxy Maize Delays Development of Diabetes in Zucker Diabetic Fatty Rats
Hedemann, M. S., Hermansen, K., Pedersen, S., & Knudsen, K. E. B. (2017) · Journal of Nutrition · doi:10.3945/jn.116.243899 · Cited by 22
Circulating GLP-1 Levels as a Potential Indicator of Metabolic Syndrome Risk in Adult Women
Seon, M. J., Hwang, S. Y., Son, Y., Song, J., & Kim, O. Y. (2021) · Nutrients · doi:10.3390/nu13030865 · Cited by 21
Resistant starch supplementation attenuates inflammation in hemodialysis patients: a pilot study
Paiva, B. R., Esgalhado, M., Borges, N. A., Kemp, J. A., Alves, G. G., Leite, P. E. C., Macedo, R. D. A., Cardozo, L., de Brito, J. S., & Mafra, D. (2020) · International Urology and Nephrology · doi:10.1007/s11255-020-02392-3 · Cited by 22
A comparative study on nutritive peculiarities of 24 Chinese cowpea cultivars
Bai, Z., Huang, X., Jinxia, M., Kan, L., & Nie, S. (2020) · Food and Chemical Toxicology · doi:10.1016/j.fct.2020.111841 · Cited by 21
A Paleolithic diet lowers resistant starch intake but does not affect serum trimethylamine-N-oxide concentrations in healthy women
Genoni, A., Lo, J., Lyons‐Wall, P., Boyce, M. C., Christophersen, C. T., Bird, A. R., & Devine, A. (2018) · British Journal Of Nutrition · doi:10.1017/s000711451800329x · Cited by 20
Components of the Fiber Diet in the Prevention and Treatment of IBD—An Update
Ferenc, K., Jarmakiewicz-Czaja, S., & Filip, R. (2022) · Nutrients · doi:10.3390/nu15010162 · Cited by 21
Effect of sourdough fermentation and baking process severity on bioactive fiber compounds in immature and ripe wheat flour bread
Saa, D. T., Di Silvestro, R., Nissen, L., Dinelli, G., & Gianotti, A. (2018) · LWT · doi:10.1016/j.lwt.2017.10.046 · Cited by 19
Development of Resistant Starch Film Coated Microparticles for an Oral Colon‐Specific Drug Delivery
Khan, A., Bibi, A., Ali, H., Rehman, A. U., Qindeel, M., Irfan, M., Shah, A. A., Badshah, M., Hasan, F., & Khan, S. (2020) · Starch - Stärke · doi:10.1002/star.201900262 · Cited by 19
Starch and β-glucan in a whole-grain-like structural form improve hepatic insulin sensitivity in diet-induced obese mice
Luo, K., Wang, X., & Zhang, G. (2019) · Food & Function · doi:10.1039/c9fo00798a · Cited by 19
Resistant Starch Has No Effect on Appetite and Food Intake in Individuals with Prediabetes
White, U. A., Peterson, C. M., Beyl, R. A., Martin, C. K., & Ravussin, É. (2020) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2020.01.017 · Cited by 20
Effects of potato resistant starch intake on insulin sensitivity, related metabolic markers and appetite ratings in men and women at risk for type 2 diabetes: a pilot cross‐over randomised controlled trial
Sanders, L., Dicklin, M. R., Palacios, O. M., Maki, C., Wilcox, M. L., & Maki, K. C. (2020) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.12822 · Cited by 19
Intake of Potatoes Is Associated with Higher Diet Quality, and Improved Nutrient Intake and Adequacy among US Adolescents: NHANES 2001–2018 Analysis
Agarwal, S., & Fulgoni, V. L. I. (2021) · Nutrients · doi:10.3390/nu13082614 · Cited by 19
Impact of resistant vs. digested starch on starch energy value in the pig gut
Fouhse, J. M., & Zijlstra, R. T. (2017) · Bioactive Carbohydrates and Dietary Fibre · doi:10.1016/j.bcdf.2017.08.001 · Cited by 19
Effects of Resistant Starch Supplementation on Glucose Metabolism, Lipid Profile, Lipid Peroxidation Marker, and Oxidative Stress in Overweight and Obese Adults: Randomized, Double-Blind, Crossover Trial
Eshghi, F., Bakhshimoghaddam, F., Rasmi, Y., & Alizadeh, M. (2019) · Clinical Nutrition Research · doi:10.7762/cnr.2019.8.4.318 · Cited by 19
Starch Polysaccharides in the Human Diet: Effect of the Different Source and Processing on its Absorption
Perin, D., & Murano, E. (2017) · Natural Product Communications · doi:10.1177/1934578x1701200606 · Cited by 19
Resistant potato starches (type 4 RS) exhibit varying effects on laxation with and without phylum level changes in microbiota: A randomised trial in young adults
Dahl, W. J., Ford, A., Ukhanova, M., Radford, A., Christman, M. C., Waugh, S. G., & Mai, V. (2016) · Journal of Functional Foods · doi:10.1016/j.jff.2016.02.013 · Cited by 18
The Effects of Resistant Starch on Biomarkers of Inflammation and Oxidative Stress: A Systematic Review and Meta-Analysis
Wei, Y., Zhang, X., Meng, Y., Wang, Q., Xu, H., & Chen, L. (2022) · Nutrition and Cancer · doi:10.1080/01635581.2021.2019284 · Cited by 17
Resistant Starch Modified Cassava Flour (MOCAF) Improves Insulin Resistance
Firdaus, J., Sulistyani, E., & Subagio, A. (2017) · Asian Journal of Clinical Nutrition · doi:10.3923/ajcn.2018.32.36 · Cited by 21
Novel Resistant Starch Type 4 Products of Different Starch Origins, Production Methods, and Amounts Are Not Equally Fermented when Fed to Sprague‐Dawley Rats
Coulon, D. B., Page, R. C., Raggio, A. M., Guice, J. L., Marx, B., Gourineni, V., Stewart, M., & Keenan, M. J. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201900901 · Cited by 17
Self-citation
Tuber flours improve intestinal health and modulate gut microbiota composition
Xu, T., Huang, W., Liang, J., Zhong, Y., Chen, Q., Jie, F., & Lu, B. (2021) · Food Chemistry X · doi:10.1016/j.fochx.2021.100145 · Cited by 17
Genome-Wide Association Study of Starch Properties in Local Thai Rice
Praphasanobol, P., Purnama, P. R., Junbuathong, S., Chotechuen, S., Moung-Ngam, P., Kasettranan, W., Paliyavuth, C., Comai, L., Pongpanich, M., Buaboocha, T., et al. (2023) · Plants · doi:10.3390/plants12183290 · Cited by 16
Cutting-edge progress in green technologies for resistant starch type 3 and type 5 preparation: An updated review
Tappiban, P., Sraphet, S., Srisawad, N., Ahmed, S., Bao, J., & Triwitayakorn, K. (2024) · Food Chemistry X · doi:10.1016/j.fochx.2024.101669 · Cited by 16
Unripe banana flour (Musa cavendishii) promotes decrease in weight gain and elimination of fecal cholesterol in Wistar rats
Escobar, A., Rocha‐Gomes, A., dos Reis, C. G. M., Herrera, K. N. S., Guedes, T. D. J., da Silva, A. A., Lessa, M. R., Pinto, N. A. V. D., & Riul, T. R. (2019) · Nutrition & Food Science · doi:10.1108/nfs-12-2018-0337 · Cited by 16
A mix of dietary fermentable fibers improves lipids handling by the liver of overfed minipigs
Mohamed, A. B., Rémond, D., Chambon, C., Sayd, T., Hébraud, M., Capel, F., Cohade, B., Hafnaoui, N., Béchet, D., Coudy‐Gandilhon, C., et al. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.12.002 · Cited by 16
Resistant starch reduces glycolysis by HK2 and suppresses high-fructose corn syrup-induced colon tumorigenesis
Zhang, Y., Shen, W., Chen, Z., He, J., Feng, L., Wang, L., & Chen, S. (2024) · Journal of Gastroenterology · doi:10.1007/s00535-024-02138-3 · Cited by 13
Dietary resistant starch ameliorating lipopolysaccharide-induced inflammation in meat ducks associated with the alteration in gut microbiome and glucagon-like peptide 1 signaling
Qin, S., Bai, W., Applegate, T. J., Zhang, K., Tian, G., Ding, X., Bai, S., Wang, J., Lv, L., Peng, H., et al. (2022) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-022-00735-x · Cited by 14
Glucose and lipid metabolism of broiler chickens fed diets with graded levels of corn resistant starch
Liu, Y. S., Zhang, Y. Y., Xing, T., Li, J. L., Wang, X., Zhu, X., Zhang, L., & Gao, F. (2020) · British Poultry Science · doi:10.1080/00071668.2020.1774511 · Cited by 12
Sweet Potato (Ipomoea batatas): An Intervention Food in Management of Food and Nutritional Security in South Asia
Waseem, M., Saeed, W., & Khan, M. A. (2023) · Springer eBooks · doi:10.1007/978-3-031-37077-9_15 · Cited by 12
On Processing Potato. 4. Survey of the Nutritional and Sensory Value of Products and Dishes
Haverkort, A. J., Linnemann, A. R., Struik, P. C., & Wiskerke, J. S. C. (2022) · Potato Research · doi:10.1007/s11540-022-09568-7 · Cited by 12
Dietary Resistant Starch Supplementation Increases High-Density Lipoprotein Particle Number in Pigs Fed a Western Diet
Rideout, T. C., Harding, S., Raslawsky, A., & Rempel, C. (2016) · Journal of Dietary Supplements · doi:10.1080/19390211.2016.1229371 · Cited by 12
The impact of the novel starch-lipid complexes on the glucolipids metabolism, inflammation, and gut dysbiosis of type 2 diabetes mellitus rats
Lu, Y., Qin, R., Wang, J., Xiang, F., Zhang, Y., Zhang, B., Fan, D., Lv, H., Ji, X., Wang, S., et al. (2024) · Food Science and Human Wellness · doi:10.26599/fshw.2023.9250008 · Cited by 12
High Resistant Starch Rice: Variation in Starch Related SNPs, and Functional, and Sensory Properties
Chen, M., Bett‐Garber, K. L., Lea, J. M., McClung, A. M., & Bergman, C. J. (2021) · Foods · doi:10.3390/foods11010094 · Cited by 11
The Influence of Probiotics Consumption on Management of Prediabetic State: A Systematic Review of Clinical Trials
Alamdary, S. Z., Afifirad, R., Asgharzadeh, S., Asadollahi, P., Ari, M. M., Dashtibin, S., Sabaghan, M., Shokouhamiri, M. R., Ghanavati, R., & Darbandi, A. (2022) · International Journal of Clinical Practice · doi:10.1155/2022/5963679 · Cited by 11
Simpson’s paradox in proof-of-concept studies
Janket, S., Ackerson, L. K., & Diamandis, E. P. (2019) · Nature Medicine · doi:10.1038/s41591-019-0624-y · Cited by 11
A novel fiber composite ingredient incorporated into a beverage and bar blunts postprandial serum glucose and insulin responses: a randomized controlled trial
O’Connor, L. E., & Campbell, W. W. (2015) · Nutrition Research · doi:10.1016/j.nutres.2015.11.015 · Cited by 10
Body Composition of Young Women and the Consumption of Selected Nutrients
Karpińska, E., Moskwa, J., Puścion‐Jakubik, A., Naliwajko, S. K., Soroczyńska, J., Markiewicz‐Żukowska, R., & Socha, K. (2022) · Nutrients · doi:10.3390/nu15010129 · Cited by 12
Role or Synergistic Interaction of Adenosine and Vitamin D3 Alongside High-Intensity Interval Training and Isocaloric Moderate Intensity Training on Metabolic Parameters: Protocol for an Experimental Study
Mirghani, S. J., Peeri, M., Yekani, O. Y., Zamani, M., Feizolahi, F., Nikbin, S., Derakhshideh, A., Mousavi, N., Khojasteh, Z., Nasrollahi, Z., et al. (2018) · JMIR Research Protocols · doi:10.2196/10753 · Cited by 10
Prebiotics for Probiotics
Vinayak, A., Mudgal, G., Sharma, S., & Singh, G. B. (2020) · Microorganisms for sustainability · doi:10.1007/978-981-15-6795-7_4 · Cited by 10
A Potential of Coleus Tuberosus Crackers Rich in Resistant Starch Type 3 Improves Glucose and Lipid Profile of Alloxan –Induced Diabetic Mice
Nugraheni, M., Hamidah, S., & Auliana, R. (2017) · Current Research in Nutrition and Food Science Journal · doi:10.12944/crnfsj.5.3.16 · Cited by 10
Gut Health Function of Instant Dehydrated Rice Sticks Substituted with Resistant Starch Types 2 and 4
Alfilasari, N., Sirivongpaisal, P., & Wichienchot, S. (2021) · Current Microbiology · doi:10.1007/s00284-021-02564-z · Cited by 9
Short-term changes in dietary fat levels and starch sources affect weight management, glucose and lipid metabolism, and gut microbiota in adult cats
Mo, R., Zhang, M., Wang, H., Liu, T., Zhang, G., & Wu, Y. (2023) · Journal of Animal Science · doi:10.1093/jas/skad276 · Cited by 13
The Effect of Type 2 Resistant Starch and Indole-3-Propionic Acid on Ameliorating High-Fat-Diet-Induced Hepatic Steatosis and Gut Dysbiosis
Yang, M., Cai, W., Li, X., Deng, Y., Li, J., Wang, X., Zhu, L., Wang, C., & Li, X. (2024) · Foods · doi:10.3390/foods13111625 · Cited by 9
Modulation of gut microbiota by rice starch enzymatically modified using amylosucrase from Deinococcus geothermalis
Song, E., Lee, E., So, Y.-S., Lee, C., Nam, Y., Lee, B., & Seo, D. (2023) · Food Science and Biotechnology · doi:10.1007/s10068-022-01238-1 · Cited by 8
Construction of local gene network for revealing different liver function of rats fed deep-fried oil with or without resistant starch
Wang, Z., Liao, T., Zhou, Z., Wang, Y., Diao, Y., Strappe, P., Prenzler, P. D., Ayton, J., & BLANCHARD, C. L. (2016) · Toxicology Letters · doi:10.1016/j.toxlet.2016.06.2101 · Cited by 8
Effect of resistant and digestible rice starches on human cytokine and lactate metabolic networks in serum
Wang, H., & Pang, G. (2017) · Cytokine · doi:10.1016/j.cyto.2017.05.009 · Cited by 8
Comparison of utilisation and fermentation of highly cross-linked phosphate starches produced from two different plant origins, potato and tapioca in rats and humans
Hamanaka, M., Stewart, M., Miyahara, K., NAKAMURA, S., & Oku, T. (2020) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637486.2020.1754349 · Cited by 8
Consumo de frutas y vegetales en la población urbana costarricense: Resultados del Estudio Latino Americano de Nutrición y Salud (ELANS)-Costa Rica
Gómez, G., Quesada, D., & Chinnock, A. (2020) · Población y Salud en Mesoamérica · doi:10.15517/psm.v18i1.42383 · Cited by 12
Potato Preload Mitigated Postprandial Glycemic Excursion in Healthy Subjects: An Acute Randomized Trial
Zhao, W., Zhou, Y., Yuan, Y., Fan, Z., Wu, Y., Liu, A., & Lu, X. (2020) · Nutrients · doi:10.3390/nu12092759 · Cited by 8
Genotyping-by-sequencing based QTL mapping identified a novel waxy allele contributing to high amylose starch in wheat
Mishra, A., Sharma, V., Rahim, M. S., Sonah, H., Pal, D., Mantri, S. S., Sharma, T. R., & Roy, J. K. (2021) · Euphytica · doi:10.1007/s10681-021-02861-5 · Cited by 7
Evaluation of digestively resistant or soluble fibers, short- and medium-chain fatty acids, trace minerals, and antibiotics in nonchallenged nursery pigs on performance, digestibility, and intestinal integrity
Kerr, B. J., Trachsel, J., Bearson, B. L., Loving, C. L., Bearson, S. M. D., Byrne, K. A., Pearce, S., Ramirez, S. M., Gabler, N. K., Schweer, W., et al. (2022) · Journal of Animal Science · doi:10.1093/jas/skac282 · Cited by 7
Microbiome–Metabolomic Analysis Reveals Beneficial Effects of Dietary Kelp Resistant Starch on Intestinal Functions of Hybrid Snakeheads (Channa maculata ♀ × Channa argus ♂)
Wang, S., Zuo, Z., Ye, B., Li, Z., Cheng, Y., Xie, S., Zou, J., & Xu, G. (2023) · Antioxidants · doi:10.3390/antiox12081631 · Cited by 7
Starch and Starch-Associated Proteins: Impacts on Wheat Grain Quality
Regina, A., & Guzmán, C. (2020) · Springer eBooks · doi:10.1007/978-3-030-34163-3_3 · Cited by 7
Genome-Wide Identification, Bioinformatic Characterization, and Expression Profiling of Starch Synthase (SS) Genes in Foxtail Millet under Drought Condition
Amoah, J. N., Adu-Gyamfi, M. O., & Kwarteng, A. O. (2024) · Stresses · doi:10.3390/stresses4030033 · Cited by 6
Potato
Sharma, S., Jaiswal, A. K., & Jaiswal, S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-812780-3.00021-0 · Cited by 6
Can Enzyme‐Resistant Starch Snack Prevent Blood Glucose Fluctuations? A Pilot Trial in Patients with Insulin‐Treated Type 2 Diabetes
Cesur, F., Seçkiner, S., Küçükerdönmez, Ö., Çağındı, Ö., Saygili, L. F., & Meseri, R. (2023) · Starch - Stärke · doi:10.1002/star.202200279 · Cited by 7
Type 2–resistant starch and Lactiplantibacillus plantarum NCIMB 8826 result in additive and interactive effects in diet-induced obese mice
Barouei, J., Martinic, A., Bendiks, Z., Mishchuk, D. O., Heeney, D. D., Slupsky, C. M., & Marco, M. L. (2023) · Nutrition Research · doi:10.1016/j.nutres.2023.07.003 · Cited by 6
Metabolic Responses to Native Wheat Starch (MidsolTM 50) versus Resistant Wheat Starch Type 4 (Fibersym® RW): Standard versus Marketplace Testing Protocols
Steele, T. J., Maniñgat, C. C., Seib, P. A., Haub, M. D., & Rosenkranz, S. K. (2021) · Current Developments in Nutrition · doi:10.1093/cdn/nzab011 · Cited by 6
Designer foods as an effective approach to enhance disease preventative properties of food through its health functionalities
Ho, L., Tan, T., & Chong, L.-C. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91001-9.00031-1 · Cited by 6
High-resistant starch and low-glutelin content 1 rice benefits gut function in obese patients
Zhou, T., Tang, Z., Liu, R., Gui, L., Luo, W., Yang, Y., & Zhang, B. (2024) · Frontiers in Sustainable Food Systems · doi:10.3389/fsufs.2024.1364403 · Cited by 6
Octenyl Succinic Anhydride-Modified Starch Attenuates Body Weight Gain and Changes Intestinal Environment of High-Fat Diet-Fed Mice
Chen, J., Kuerbanjiang, M., Zhang, Y., Cheng, H., Lin, B., Yue, P., Wang, L.-H., Liu, F., Shi, J., Wan, Z., et al. (2022) · Foods · doi:10.3390/foods11192980 · Cited by 6
Enhancing Functional Properties and Shelf Life of Oryza sativa L. via Grain Stabilization Techniques
Song, E., Gwon, H., Choi, J., Islam, M. A., Chun, J., Chang, Y. H., & Hwang, J. (2025) · Foods · doi:10.3390/foods14040596 · Cited by 5
The Potential Health Benefits of Resistant Starch on Human Metabolism- A Narrative Review
Chen, C., Xie, M.-Y., & Liao, D.-M. (2022) · International Journal of Integrated Medical Research · doi:10.57181/ijoimr/vol9i04/82 · Cited by 5
A narrative review on the role of gut microbiome, dietary strategies, and supplements in managing metabolic syndrome
Chopra, S., Dahiya, V., Shankar, E. M., & Saini, A. (2025) · Exploration of Drug Science · doi:10.37349/eds.2025.1008105 · Cited by 6
Nutritional Significance of Processed Potato Products
Jaiswal, A. K. (2020) · Springer eBooks · doi:10.1007/978-981-15-7662-1_14 · Cited by 5
Differences in Capacity of High-Amylose Resistant Starch, Whole-Grain Flour, and a Combination of Both to Modify Intestinal Responses of Male Sprague Dawley Rats Fed Moderate and High Fat Diets
Guice, J. L., Bendiks, Z. A., Coulon, D. B., Raggio, A. M., Page, R. C., Carvajal‐Aldaz, D., Lou, M., Welsh, D. A., Marx, B. D., Taylor, C. M., et al. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c05285 · Cited by 5
Self-citation
Role of Diet and Gut Microbiome Composition in Women with Polycystic Ovarian Syndrome (Pcos): A Systematic Review
Krishnan, N., Narayanan, P., Parvathi, V. D., & Velraja, S. (2025) · Current Research in Nutrition and Food Science Journal · doi:10.12944/crnfsj.13.2.2 · Cited by 4
Extrusion-assisted enzymatic modification slows the digestibility of rice starch by modulating its fine structure
Song, J., Liu, H., Huang, X., Wang, Y., Liu, Z. Y., Li, C., & Zhu, J. (2026) · Journal of Cereal Science · doi:10.1016/j.jcs.2026.104432 · Cited by 4
The longitudinal associations between sweet potato intake and the risk of non-alcoholic fatty liver disease: the TCLSIH cohort study
Yang, H., Zhang, T., Rayamajhi, S., Thapa, A., Du, W., Meng, G., Zhang, Q. H., Liu, L., Wu, H., Gu, Y., et al. (2022) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637486.2022.2050997 · Cited by 4
Maintaining Effective Beta Cell Function in the Face of Metabolic Syndrome-Associated Glucolipotoxicity—Nutraceutical Options
McCarty, M. F., & DiNicolantonio, J. J. (2021) · Healthcare · doi:10.3390/healthcare10010003 · Cited by 3
The Maize Contribution in the Human Health
Bañuelos‐Pineda, J., Cecilia, G.-R. C., Ricardo, C.-J., & Octavio, A. L. L. (2018) · InTech eBooks · doi:10.5772/intechopen.78700 · Cited by 4
Evaluation of grain nutritional quality and resistant starch content in Kenyan bread wheat varieties
Kariithi, S. N., Abwao, S. I., Njau, P., & Ndung’u, J. N. (2016) · African Crop Science Journal · doi:10.4314/acsj.v24i4.8 · Cited by 3
Alterações induzidas pela dieta com diferentes concentrações de amido resistente no metabolismo de carboidratos e de lipídeos, em ratos Wistar
Alves, A. A., Pigoso, A. A., Chang, Y. K., Tagliapietra, B. L., Schmiele, M. M., Campelo, P. H., & Clerici, M. T. P. S. (2021) · Research Society and Development · doi:10.33448/rsd-v10i7.16448 · Cited by 3
Almidón resistente como prebiótico y sus beneficios en el organismo humano
Olayo-Contreras, V. M., Alemán-Castillo, S. E., Rodríguez-Castillejos, G., & Castillo-Ruíz, O. (2022) · TIP Revista Especializada en Ciencias Químico-Biológicas · doi:10.22201/fesz.23958723e.2021.406 · Cited by 3
Formation of resistant starch and cracker products from leftover rice in Saudi Arabia
Bayomy, H. M., Alamri, E. S., Albalawi, A. N., Alharbi, R., Al-Maris, S., Rozan, M. A., & Shamsia, S. (2023) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2023.100832 · Cited by 3
Physical and mathematical modelling of the process of cooking minced meat with spelt flour and champignon mushrooms
Вацлавовна, Б.-П. Л., Nikolaenko, M., Mushtruk, M. M., Nazarenko, M., & Beiko, L. (2024) · Animal Science and Food Technology · doi:10.31548/animal.2.2024.38 · Cited by 3
Obesity, Diet and the Gut Microbiota
Bird, A. R., & Conlon, M. A. (2015) · Current Nutrition Reports · doi:10.1007/s13668-015-0146-2 · Cited by 3
Fresh Saengshik Showed a Positive Effect on Mitigating Dextran Sulfate Sodium-Induced Experimental Colitis in Mice
Song, J., Shin, S.-H., Park, M., Hwang, S., Ju, J., Kim, H.-Y., Kweon, M., & Park, K. (2020) · Journal of Medicinal Food · doi:10.1089/jmf.2019.4502 · Cited by 3
Breeding by Design for Functional Rice with Genome Editing Technologies
Yan, C., Meng, H., Pei, Y., Sun, W., & Zhang, J. (2025) · Journal of Visualized Experiments · doi:10.3791/67336 · Cited by 2
Millets as Functional Foods for Liver Health: Insights into the Hepatoprotective Potential of Their Biomolecules
Parinitha, A., & Lakshmi, A. J. (2026) · ACS Nutrition Science · doi:10.1021/acsnutrsci.5c00020 · Cited by 2
Removal of Toxic Cations from Aqueous Solutions using Ginger Root Waste
Onwuka, J. C., Igberi, S. A., & Akpomie, T. M. (2022) · Journal of Multidisciplinary Applied Natural Science · doi:10.47352/jmans.2774-3047.126 · Cited by 2
Dry heat whole Sorghum BRS 305 flour modulate satiety and improves antioxidant response in brain of Wistar rats fed with high-fat high-fructose diet
Lúcio, H. G., Grancieri, M., Martinez, O. D. M., Toledo, R. C. L., de Menezes, C. B., Costa, N. M. B., Queiróz, V. A. V., da Silva, B. P., & Martino, H. S. D. (2023) · Food Research International · doi:10.1016/j.foodres.2023.113252 · Cited by 2
Probiotics and prebiotics from fruit waste
Kumar, A., Kumar, A., Gehlot, R., Singh, D., & Chaudhary, T. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13842-3.00010-1 · Cited by 2
Sugarcane Fibre as Dietary Supplement, Health Benefits and Applications in Functional Foods
Suresha, G. S., Kuppusamy, H., Palanichamy, M., Rajamani, L., Kalaimani, K., Krishnappa, G., Maruthi, R. T., Swamy, H. K. M., Amaresh, Vinayaka, V., et al. (2024) · Springer eBooks · doi:10.1007/978-981-97-7228-5_17 · Cited by 2
Graphene Oxide Supported Crystal Growth of ZIF-8@ZIF-67 for Enhanced Antibacterial Performance
Wang, C., Yang, R., Yu, X., Yuan, B., & Yao, Y. (2025) · Journal of Inorganic and Organometallic Polymers and Materials · doi:10.1007/s10904-024-03581-8 · Cited by 2

Authors: Keenan, M. J., Zhou, J., Hegsted, M., Pelkman, C., Durham, H. A., Coulon, D. B., & Martin, R. J.
Affiliations: United States Department of Veterans Affairs (US)
University of Wisconsin–Stout (US)
Ingredion (United States) (US)
Pennington Biomedical Research Center (US)
Louisiana State University (US)
United States Department of Agriculture (US)
Corresponding author: Keenan, Michael J
ORCID: Keenan, Michael J
Coulon, Diana B
Martin, Roy J
Venue: Advances in Nutrition
Publisher: Elsevier BV
Published: 2015-03
Volume: 6
Issue: 2
Pages: 198-205
ISSN: 2156-5376 (ISSN-L)
2161-8313
DOI: 10.3945/an.114.007419
PMC: PMC4352178
OpenAlex: W2167525097
Semantic Scholar: df2931f1244729ea55b43f1db09c74b9a327e10f
Cited by: 243
References: 74
Citations by year: 2026: 9 · 2025: 10 · 2024: 16 · 2023: 16 · 2022: 32 · 2021: 26 · 2020: 37 · 2019: 29 · 2018: 22 · 2017: 25 · 2016: 15 · 2015: 6
FWCI: 2.91
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 2524 d)
Locations: Advances in Nutrition (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Civil War Book Review (submittedVersion)
Funders: Louisiana State University
Louisiana Clinical and Translational Science Center (U54GM104940, 1 U54 GM104940, GM104940)
National Institutes of Health (GM104940)
University of Illinois at Urbana-Champaign
Agricultural Center, Louisiana State University (1 U54 GM104940)
National Institute of General Medical Sciences (GM104940, U54GM104940)
National Institute of Diabetes and Digestive and Kidney Diseases (R21DK073403, R21 DK-073403-01A1)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
Keywords: resistant starch, gut health, adiposity, insulin resistance, short-chain fatty acids, gut microbiota, glucagon-like peptide-1, intestinal gluconeogenesis, adiponectin, dietary fiber, low glycemic index diet, isocaloric diet, abdominal fat, tumor cell apoptosis
MeSH terms: Gastrointestinal Microbiome, Animals, Diet, Dietary Fiber, Fatty Acids, Volatile, Fermentation, Humans, Insulin Resistance, Starch, Gastrointestinal Tract, Abdominal Fat, Adiposity, Glucagon-Like Peptide 1, Obesity, Abdominal

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Role of Resistant Starch in Improving Gut Health, Adiposity, and Insulin Resistance

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks