Cutting Edge: A Transcriptional Repressor and Corepressor Induced by the STAT3-Regulated Anti-Inflammatory Signaling Pathway

Controlling the false discovery rate in behavior genetics research

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SOCS3 negatively regulates IL-6 signaling in vivo

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IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

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Shaping Gene Expression in Activated and Resting Primary Macrophages by IL-10

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SOCS3 regulates the plasticity of gp130 signaling

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Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response

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The primary mechanism of the IL-10-regulated antiinflammatory response is to selectively inhibit transcription

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STAT3 deletion during hematopoiesis causes Crohn’s disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity

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Local-pooled-error test for identifying differentially expressed genes with a small number of replicated microarrays

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Interleukin‐10 suppression of myeloid cell activation — a continuing puzzle

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General nature of the STAT3-activated anti-inflammatory response.

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IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-α production in macrophages

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BCL-3 and NF-κB p50 Attenuate Lipopolysaccharide-induced Inflammatory Responses in Macrophages

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An EGFR/Ebi/Sno Pathway Promotes Delta Expression by Inactivating Su(H)/SMRTER Repression during Inductive Notch Signaling

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The Nuclear IκB Protein IκBNS Selectively Inhibits Lipopolysaccharide-Induced IL-6 Production in Macrophages of the Colonic Lamina Propria

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Re-examination of the Role of Suppressor of Cytokine Signaling 1 (SOCS1) in the Regulation of Toll-like Receptor Signaling

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IκBNS Inhibits Induction of a Subset of Toll-like Receptor-Dependent Genes and Limits Inflammation

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IL-10 expression profiling in human monocytes

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An Induced Ets Repressor Complex Regulates Growth Arrest during Terminal Macrophage Differentiation

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Expression of Constitutively Active STAT3 Can Replicate the Cytokine-suppressive Activity of Interleukin-10 in Human Primary Macrophages

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strawberry notch encodes a conserved nuclear protein that functions downstream of Notch and regulates gene expression along the developing wing margin of Drosophila.Preprint

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ABIN-3: a Molecular Basis for Species Divergence in Interleukin-10-Induced Anti-Inflammatory Actions

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Happy 5th birthday Current Opinion in Pharmacology!

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PE-1/METS, an Antiproliferative Ets Repressor Factor, Is Induced by CREB-1/CREM-1 during Macrophage Differentiation

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The IκB Protein Bcl-3 Negatively Regulates Transcription of the IL-10 Gene in Macrophages

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Epitope Tagging of the Human Endoplasmic Reticulum HSP70 Protein, BiP, to Facilitate Analysis of BiP-Substrate Interactions

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Biology and therapeutic potential of interleukin-10

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Biology of interleukin-10

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Interleukins, from 1 to 37, and interferon-γ: Receptors, functions, and roles in diseases

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STAT3 signaling in immunity

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The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer

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Cancer and Inflammation: An Old Intuition with Rapidly Evolving New Concepts

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The IL-10/STAT3-mediated anti-inflammatory response: recent developments and future challenges

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Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 To Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution

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Regulatory T cells and inhibitory cytokines in autoimmunity

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IL-10 Inhibits miR-155 Induction by Toll-like Receptors

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Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease

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The Role of Macrophages and Dendritic Cells in the Initiation of Inflammation in IBD

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Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling?

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Regulation of interleukin‐12/interleukin‐23 production and the T‐helper 17 response in humans

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STAT3 in CD4+ T helper cell differentiation and inflammatory diseases

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Regulation of Antitumor Immune Responses by the IL‐12 Family Cytokines, IL‐12, IL‐23, and IL‐27

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The nasal methylome as a biomarker of asthma and airway inflammation in children

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Exploring the Pivotal Immunomodulatory and Anti‐Inflammatory Potentials of Glycyrrhizic and Glycyrrhetinic Acids

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Molecular mechanisms of alcoholic liver disease: Innate immunity and cytokines

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Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways

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Astrocytic Regulation of Human Monocytic/Microglial Activation

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Large-Scale Discovery of ERK2 Substrates Identifies ERK-Mediated Transcriptional Regulation by ETV3

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Understanding the molecular mechanisms of the multifaceted IL‐10‐mediated anti‐inflammatory response: Lessons from neutrophils

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Genome-wide analysis of STAT3 binding in vivo predicts effectors of the anti-inflammatory response in macrophages

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Monocyte differentiation and macrophage polarization

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The Role of Intestinal Macrophages in Gastrointestinal Homeostasis: Heterogeneity and Implications in Disease

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Formaldehyde: Integrating Dosimetry, Cytotoxicity, and Genomics to Understand Dose-Dependent Transitions for an Endogenous Compound

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Inhibition of JAKs in Macrophages Increases Lipopolysaccharide-Induced Cytokine Production by Blocking IL-10–Mediated Feedback

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IL-10 Suppresses Calcium-Mediated Costimulation of Receptor Activator NF-κB Signaling during Human Osteoclast Differentiation by Inhibiting TREM-2 Expression

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Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

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Classification of four distinct osteoarthritis subtypes with a knee joint tissue transcriptome atlas

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Tristetraprolin Is Required for Full Anti-Inflammatory Response of Murine Macrophages to IL-10

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Interleukin-10-induced gene expression and suppressive function are selectively modulated by the PI3K-Akt-GSK3 pathway

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Neuropeptide Y Is Produced by Adipose Tissue Macrophages and Regulates Obesity-Induced Inflammation

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Review: Molecular mechanism of microglia stimulated glioblastoma invasion

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The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls

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IL-10 Regulates Il12b Expression via Histone Deacetylation: Implications for Intestinal Macrophage Homeostasis

Kobayashi, T., Matsuoka, K., Sheikh, S. Z., Russo, S. M., Mishima, Y., Collins, C. B., de Zoeten, E. F., Karp, C. L., Ting, J. P. ‐., Sartor, R. B., et al. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1200042 · Cited by 83 · see citing works

MOTS-c peptide increases survival and decreases bacterial load in mice infected with MRSA

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Distinct transcriptional regulatory modules underlie STAT3’s cell type-independent and cell type-specific functions

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A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly in anti-citrullinated peptide antibody-negative disease

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Macrophage polarization toward M1 phenotype through NF-κB signaling in patients with Behçet’s disease

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From SNPs to Genes: Disease Association at the Gene Level

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Suppression of TNF-α and IL-1 Signaling Identifies a Mechanism of Homeostatic Regulation of Macrophages by IL-27

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Molecular Characterization of Transcriptome-wide Interactions between Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus and Porcine Alveolar Macrophages in vivo

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A Distal Enhancer in Il12b Is the Target of Transcriptional Repression by the STAT3 Pathway and Requires the Basic Leucine Zipper (B-ZIP) Protein NFIL3

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Spinal interleukin-10 produces antinociception in neuropathy through microglial β-endorphin expression, separated from antineuroinflammation

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Construction and analysis of the protein-protein interaction networks for schizophrenia, bipolar disorder, and major depression

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IL-10 targets IRF transcription factors to suppress IFN and inflammatory response genes by epigenetic mechanisms

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Gene Expression Signature-Based Screening Identifies New Broadly Effective Influenza A Antivirals

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Genomic analysis of LPS-stimulated myeloid cells identifies a common pro-inflammatory response but divergent IL-10 anti-inflammatory responses

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Networks controlling mRNA decay in the immune system

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Extracellular CIRP induces macrophage endotoxin tolerance through IL-6R–mediated STAT3 activation

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ETV3 and ETV6 enable monocyte differentiation into dendritic cells by repressing macrophage fate commitment

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Adiponectin Receptor Signaling on Dendritic Cells Blunts Antitumor Immunity

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DNA Methylation and Age-Independent Cardiovascular Risk, an Epigenome-Wide Approach

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Murine Oncostatin M Acts via Leukemia Inhibitory Factor Receptor to Phosphorylate Signal Transducer and Activator of Transcription 3 (STAT3) but Not STAT1, an Effect That Protects Bone Mass

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Curation of over 10 000 transcriptomic studies to enable data reuse

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Functional screen of inflammatory bowel disease genes reveals key epithelial functions

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Pegylated <scp>IL</scp>‐10 induces cancer immunity: The surprising role of IL‐10 as a potent inducer of IFN‐γ‐mediated CD8⁺ T cell cytotoxicity

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Epigenome-wide association in adipose tissue from the METSIM cohort

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Interleukin-10 Inhibits Lipopolysaccharide-induced Tumor Necrosis Factor-α Translation through a SHIP1-dependent Pathway

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An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression

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Genetic Diversities and Differentially Selected Regions Between Shandong Indigenous Pig Breeds and Western Pig Breeds

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Endogenous suppression of mast cell development and survival by IL-4 and IL-10

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Human granulosa cells function as innate immune cells executing an inflammatory reaction during ovulation: a microarray analysis

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Spatial congregation of STAT binding directs selective nuclear architecture during T-cell functional differentiationPreprint

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Altered DNA methylation underlies monocyte dysregulation and immune exhaustion memory in sepsis

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Cytosolic Phospholipase A2α and Eicosanoids Regulate Expression of Genes in Macrophages Involved in Host Defense and Inflammation

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Salmonella enterica serovar Typhimurium-infected pigs with different shedding levels exhibit distinct clinical, peripheral cytokine and transcriptomic immune response phenotypes

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Dissecting the cellular landscape and transcriptome network in viral myocarditis by single-cell RNA sequencing

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Genome-wide analyses reveal the extent of opportunistic STAT5 binding that does not yield transcriptional activation of neighboring genes

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Damage-Associated Molecular Patterns As Double-Edged Swords in Sepsis

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Inhibition of TLR4-Induced IκB Kinase Activity by the RON Receptor Tyrosine Kinase and Its Ligand, Macrophage-Stimulating Protein

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Hydroxy-safflor yellow A inhibits neuroinflammation mediated by Aβ1–42 in BV-2 cells

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IL-10 disrupts the Brd4-docking sites to inhibit LPS-induced CXCL8 and TNF-α expression in monocytes: Implications for chronic obstructive pulmonary disease

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Jing-Fang n-butanol extract and its isolated JFNE-C inhibit ferroptosis and inflammation in LPS induced RAW264.7 macrophages via STAT3/p53/SLC7A11 signaling pathway

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High prevalence of germline STK11mutations in Hungarian Peutz-Jeghers Syndrome patients

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Production of TNF-α in Macrophages Activated by T Cells, Compared with Lipopolysaccharide, Uses Distinct IL-10–Dependent Regulatory Mechanism

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Targeting STAT-3 signaling pathway in cancer for development of novel drugs: Advancements and challenges

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Different gene response to mechanical loading during early and late phases of rat Achilles tendon healing

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LPS-Induced G-CSF Expression in Macrophages Is Mediated by ERK2, but Not ERK1

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Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

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The Atherosclerotic Plaque Microenvironment as a Therapeutic Target

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Genetic variants involved in innate immunity modulate the risk of inflammatory bowel diseases in an understudied Malaysian population

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Genome-Wide Detection of Copy Number Variations and Their Association With Distinct Phenotypes in the World’s Sheep

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Review and Meta-Analyses of TAAR1 Expression in the Immune System and Cancers

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Molecular Profiling of a Rare Rosette-Forming Glioneuronal Tumor Arising in the Spinal Cord

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Psoriasis-Specific RNA Isoforms Identified by RNA-Seq Analysis of 173,446 Transcripts

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Identification of Gene Transcription Start Sites and Enhancers Responding to Pulmonary Carbon Nanotube Exposure in Vivo

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Identification of contributing genes of Huntington’s disease by machine learning

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Analysis of Genes Associated With Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn’s Disease

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Breakpoint determination of 15 large deletions in Peutz–Jeghers subjects

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Evaluation of selected IL6/STAT3 pathway molecules and miRNA expression in chronic obstructive pulmonary disease

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Differentiation of stem cells derived from carious teeth into dopaminergic‐like cells

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Indeterminate cell histiocytosis: A systematic review of the literature with a comprehensive revision of clinical, histopathological, and molecular features

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Interleukin-22 promotes proliferation and reverses LPS-induced apoptosis and steroidogenesis attenuation in human ovarian granulosa cells: implications for polycystic ovary syndrome pathogenesis

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Mechanisms of Interleukin-10-Mediated Immunosuppression in Viral Infections

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Signal Transducer and Activator of Transcription 3 Is the Dominant Mediator of the Anti-Inflammatory Effects of IL-10 in Human Macrophages

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Cutting Edge: IL-10–Mediated Tristetraprolin Induction Is Part of a Feedback Loop That Controls Macrophage STAT3 Activation and Cytokine Production

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The primary mechanism of the IL-10-regulated antiinflammatory response is to selectively inhibit transcription

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Expression of Constitutively Active STAT3 Can Replicate the Cytokine-suppressive Activity of Interleukin-10 in Human Primary Macrophages

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