Lung Macrophages Serve as Obligatory Intermediate between Blood Monocytes and Alveolar Macrophages

Monocyte and macrophage heterogeneity

Gordon, S., & Taylor, P. R. (2005) · Nature Reviews Immunology · doi:10.1038/nri1733 · Cited by 5,190

Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties

Geissmann, F., Jung, S., & Littman, D. R. (2003) · Immunity · doi:10.1016/s1074-7613(03)00174-2 · Cited by 3,504

Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., & Littman, D. R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.11.4106-4114.2000 · Cited by 2,632

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens.

Jung, S., Unutmaz, D., Wong, P., Sano, G., Santos, K. D. L., Sparwasser, T., Wu, S., Vuthoori, S., Ko, K., Zavala, F., et al. (2002) · Immunity · doi:10.1016/s1074-7613(02)00365-5 · Cited by 1,953

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

Kitamura, D., Roes, J., Kühn, R., & Rajewsky, K. (1991) · Nature · doi:10.1038/350423a0 · Cited by 1,783

THE ORIGIN AND KINETICS OF MONONUCLEAR PHAGOCYTES

van Furth, R., & Cohn, Z. A. (1968) · The Journal of Experimental Medicine · doi:10.1084/jem.128.3.415 · Cited by 1,564

In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma

van Rijt, L. V., Jung, S., KleinJan, A., Vos, N., Willart, M., Duez, C., Hoogsteden, H., & Lambrecht, B. (2005) · Journal of Experimental Medicine · doi:10.1084/jem.20042311 · Cited by 704

Expression cloning of a diphtheria toxin receptor: Identity with a heparin-binding EGF-like growth factor precursor

Naglich, J. G., Metherall, J. E., Russell, D. W., & Eidels, L. (1992) · Cell · doi:10.1016/0092-8674(92)90623-k · Cited by 557

Dendritic Cells in the Pathogenesis of Sarcoidosis

Zaba, L. C., Smith, G. P., Sanchez, M., & Prystowsky, S. D. (2009) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2009-0033tr · Cited by 63

Plexin C1 deficiency permits synaptotagmin 7–mediated macrophage migration and enhances mammalian lung fibrosis

Peng, X., Moore, M. W., Mathur, A., Zhou, Y., Sun, H., Gan, Y., Herazo‐Maya, J. D., Kaminski, N., Hu, X., Pan, H., et al. (2016) · The FASEB Journal · doi:10.1096/fj.201600373r · Cited by 60

Bitter taste signaling in tracheal epithelial brush cells elicits innate immune responses to bacterial infection

Hollenhorst, M. I., Nandigama, R., Evers, S. B., Gamayun, I., Wadood, N. A., Salah, A., Pieper, M., Wyatt, A. K., Stukalov, A., Gebhardt, A., et al. (2022) · Journal of Clinical Investigation · doi:10.1172/jci150951 · Cited by 61

Recruited Exudative Macrophages Selectively Produce CXCL10 after Noninfectious Lung Injury

Tighe, R. M., Liang, J., Liu, N., Jung, Y., Jiang, D., Gunn, M. D., & Noble, P. W. (2011) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2010-0471oc · Cited by 61

Expression of neuroimmune semaphorins 4A and 4D and their receptors in the lung is enhanced by allergen and vascular endothelial growth factor

Smith, E., Shanks, K., Lipsky, M. M., DeTolla, L. J., Keegan, A. D., & Chapoval, S. P. (2011) · BMC Immunology · doi:10.1186/1471-2172-12-30 · Cited by 61

Intrapulmonary Cellular-Level Distribution of Inhaled Nanoparticles with Defined Functional Groups and Its Correlations with Protein Corona and Inflammatory Response

Yin, B., Chan, C. K. W., Liu, S., Hong, H., Wong, S. H. D., Lee, L. K. C., Ho, L. W. C., Zhang, L., Leung, K. C., Choi, P. C., et al. (2019) · ACS Nano · doi:10.1021/acsnano.9b06424 · Cited by 62

Origin, Localization, and Immunoregulatory Properties of Pulmonary Phagocytes in Allergic Asthma

Hoffmann, F. S., Ender, F., Schmudde, I., Lewkowich, I. P., Köhl, J., König, P., & Laumonnier, Y. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00107 · Cited by 62

Whole-Lung Irradiation Results in Pulmonary Macrophage Alterations that are Subpopulation and Strain Specific

Groves, A. M., Johnston, C. J., Misra, R. S., Williams, J. P., & Finkelstein, J. N. (2015) · Radiation Research · doi:10.1667/rr14178.1 · Cited by 58

Macrophage-derived cytokines in pneumonia: Linking cellular immunology and genetics

Dukhinova, M., Kokinos, E. K., Kuchur, P. D., Komissarov, A., & Штро, А. А. (2020) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2020.11.003 · Cited by 59

Regulation of macrophage functions by FABP-mediated inflammatory and metabolic pathways

Jin, R., Hao, J., Yi, Y., Sauter, E. R., & Li, B. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2021.158964 · Cited by 54

Activation and polarization of circulating monocytes in severe chronic obstructive pulmonary disease

Cornwell, W. D., Kim, V., Fan, X., Vega, M. E., Ramsey, F. V., Criner, G. J., & Rogers, T. J. (2018) · BMC Pulmonary Medicine · doi:10.1186/s12890-018-0664-y · Cited by 54

Distinctive Effects of GM-CSF and M-CSF on Proliferation and Polarization of Two Major Pulmonary Macrophage Populations

Draijer, C., Penke, L. R. K., & Peters-Golden, M. L. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1801387 · Cited by 60

The Progress of Therapeutic Vaccination with Regard to Tuberculosis

Cardona, P.-J. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01536 · Cited by 55

Pulmonary dendritic cell development and antigen acquisition

Desch, A. N., Henson, P. M., & Jakubzick, C. (2012) · Immunologic Research · doi:10.1007/s12026-012-8359-6 · Cited by 52

Defining In Vivo Dendritic Cell Functions Using CD11c-DTR Transgenic Mice

Bar‐On, L., & Jung, S. (2009) · Methods in molecular biology · doi:10.1007/978-1-60761-421-0_28 · Cited by 50

Gpnmb and Spp1 mark a conserved macrophage injury response masking fibrosis-specific programming in the lung

King, E. M., Zhao, Y., Moore, C. M., Steinhart, B., Anderson, K. C., Vestal, B. E., Moore, P. K., McManus, S. A., Evans, C. M., Mould, K. J., et al. (2024) · JCI Insight · doi:10.1172/jci.insight.182700 · Cited by 52

Essential Role of mTORC1 in Self-Renewal of Murine Alveolar Macrophages

Deng, W., Yang, J., Lin, X., Shin, J., Gao, J., & Zhong, X. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1501845 · Cited by 47

IN VITRO MODELING OF HUMAN ALVEOLAR MACROPHAGE SMOKE EXPOSURE: ENHANCED INFLAMMATION AND IMPAIRED FUNCTION

Winkler, A. R., Nocka, K. H., Sulahian, T. H., Kobzik, L., & Williams, C. M. M. (2008) · Experimental Lung Research · doi:10.1080/01902140802366261 · Cited by 47

A Mathematical Model of Idiopathic Pulmonary Fibrosis

Hao, W., Marsh, C. B., & Friedman, A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135097 · Cited by 47

Ozone Inhalation Promotes CX3CR1-Dependent Maturation of Resident Lung Macrophages That Limit Oxidative Stress and Inflammation

Tighe, R. M., Li, Z., Potts, E. N., Frush, S., Liu, N., Gunn, M. D., Foster, W. M., Noble, P. W., & Hollingsworth, J. W. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1101312 · Cited by 44

Heterogeneity of lung mononuclear phagocytes during pneumonia: contribution of chemokine receptors

Chen, L., Zhang, Z., Barletta, K. E., Burdick, M. D., & Mehrad, B. (2013) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00194.2013 · Cited by 46

Alveolar-like Stem Cell–derived Myb − Macrophages Promote Recovery and Survival in Airway Disease

Litvack, M. L., Wigle, T. J., Lee, J., Wang, J., Ackerley, C. A., Grunebaum, E., & Post, M. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201509-1838oc · Cited by 46

Single-cell RNA sequencing reveals unique monocyte-derived interstitial macrophage subsets during lipopolysaccharide-induced acute lung inflammation

Moore, P. K., Anderson, K. C., McManus, S. A., Tu, T.-H. C., King, E. M., Mould, K. J., Redente, E. F., Henson, P. M., Janssen, W. J., & McCubbrey, A. L. (2023) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00223.2022 · Cited by 49

IL ‐1α induces CD11blow alveolar macrophage proliferation and maturation during granuloma formation

Huaux, F., Re, S. L., Giulia, G., Uwambayinema, F., Devosse, R., Yakoub, Y., Panin, N., Palmai‐Pallag, M., Rabolli, V., Delos, M., et al. (2014) · The Journal of Pathology · doi:10.1002/path.4487 · Cited by 45

Innate Immune Cell Suppression and the Link With Secondary Lung Bacterial Pneumonia

Morgan, D. J., Casulli, J., Chew, C., Connolly, E., Lui, S., Brand, O. J., Rahman, R., Jagger, C. P., & Hussell, T. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02943 · Cited by 45

Airway microbiome-immune crosstalk in chronic obstructive pulmonary disease

Kayongo, A., Robertson, N. M., Siddharthan, T., Ntayi, M. L., Ndawula, J. C., Sande, O. J., Bagaya, B. S., Kirenga, B., Mayanja‐Kizza, H., Joloba, M. L., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1085551 · Cited by 50

The Natural Cytotoxicity Receptor 1 Contribution to Early Clearance of Streptococcus pneumoniae and to Natural Killer-Macrophage Cross Talk

Elhaik-Goldman, S., Kafka, D., Yossef, R., Hadad, U., Elkabets, M., Vallon-Eberhard, A., Hulihel, L., Jung, S., Ghadially, H., Braiman, A., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023472 · Cited by 43

Blunt chest trauma induces mediator-dependent monocyte migration to the lung

Seitz, D., Niesler, U., Palmer, A., Sulger, M., Braumüller, S. T., Perl, M., Gebhard, F. T., & Knöferl, M. W. (2010) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181e8ad10 · Cited by 44

Effects of HIV-1 infection in vitro on transendothelial migration by monocytes and monocyte-derived macrophages

Westhorpe, C. L. V., Zhou, J., Webster, N. L., Kalionis, B., Lewin, S. R., Jaworowski, A., Müller, W. A., & Crowe, S. M. (2009) · Journal of Leukocyte Biology · doi:10.1189/jlb.0808501 · Cited by 42

Interleukin-33 from Monocytes Recruited to the Lung Contributes to House Dust Mite-Induced Airway Inflammation in a Mouse Model

Tashiro, H., Takahashi, K., Hayashi, S., Kato, G., Kurata, K., Kimura, S. H., & Sueoka‐Aragane, N. (2016) · PLoS ONE · doi:10.1371/journal.pone.0157571 · Cited by 41

Association of immune cell recruitment and BPD development

Heydarian, M., Schulz, C., Stoeger, T., & Hilgendorff, A. (2022) · Molecular and Cellular Pediatrics · doi:10.1186/s40348-022-00148-w · Cited by 41

Cutting Edge: CLEC5A Mediates Macrophage Function and Chronic Obstructive Pulmonary Disease Pathologies

Wortham, B. W., Eppert, B. L., Flury, J. L., García, S. M., Donica, W. R. F., Osterburg, A. R., Joyce-Shaikh, B., Cua, D. J., & Borchers, M. T. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1500978 · Cited by 38

The Lung Macrophage: A Jack of All Trades

Misharin, A. V., Budinger, G. R. S., & Perlman, H. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201107-1343ed · Cited by 42

Innate Receptors and Cellular Defense against Pulmonary Infections

Werner, J. L., & Steele, C. H. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1400978 · Cited by 40

Specific Neuropilins Expression in Alveolar Macrophages among Tissue-Specific Macrophages

Aung, N. Y., Ohe, R., Meng, H., Kabasawa, T., Yang, S., Kato, T., & Yamakawa, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147358 · Cited by 39

The Role of Macrophages in Influenza a Virus Infection

Nicol, M. Q., & Dutia, B. M. (2014) · Future Virology · doi:10.2217/fvl.14.65 · Cited by 38

Role of Recently Migrated Monocytes in Cigarette Smoke-Induced Lung Inflammation in Different Strain of Mice

Pérez-Rial, S., del Puerto‐Nevado, L., Terrón-Expósito, R., Girón-Martínez, Á., González‐Mangado, N., & Peces‐Barba, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072975 · Cited by 34

Different HIV pox viral vector-based vaccines and adjuvants can induce unique antigen presenting cells that modulate CD8 T cell avidity

Trivedi, S., Jackson, R. J., & Ranasinghe, C. (2014) · Virology · doi:10.1016/j.virol.2014.09.004 · Cited by 33

Probing in vivo dendritic cell functions by conditional cell ablation

Sapoznikov, A., & Jung, S. (2008) · Immunology and Cell Biology · doi:10.1038/icb.2008.23 · Cited by 33

Transcriptome profiling of primary murine monocytes, lung macrophages and lung dendritic cells reveals a distinct expression of genes involved in cell trafficking

Zasłona, Z., Wilhelm, J., Cakarova, L., Marsh, L. M., Seeger, W., Lohmeyer, J., & von Wulffen, W. (2009) · Respiratory Research · doi:10.1186/1465-9921-10-2 · Cited by 32

Reduced expression of monocyte CD200R is associated with enhanced proinflammatory cytokine production in sarcoidosis

Fraser, S. D., Sadofsky, L. R., Kaye, P. M., & Hart, S. P. (2016) · Scientific Reports · doi:10.1038/srep38689 · Cited by 33

Systemic response induced by Scorpaena plumieri fish venom initiates acute lung injury in mice

Boletini-Santos, D., Komegae, E. N., de Figueiredo, S. G., Haddad, V., Lopes‐Ferreira, M., & Lima, C. (2007) · Toxicon · doi:10.1016/j.toxicon.2007.11.011 · Cited by 29

L-Plastin Is Essential for Alveolar Macrophage Production and Control of Pulmonary Pneumococcal Infection

Deady, L. E., Todd, E. M., Davis, C. G., Zhou, J. Y., Topcagic, N., Edelson, B. T., Ferkol, T. W., Cooper, M. A., Muenzer, J. T., & Morley, S. C. (2014) · Infection and Immunity · doi:10.1128/iai.01199-13 · Cited by 29

Monocytes in Sterile Inflammation: Recruitment and Functional Consequences

Spahn, J. H., & Kreisel, D. (2013) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-013-0267-5 · Cited by 30

A positive feedback loop reinforces the allergic immune response in human peanut allergy

Zhou, X., Yu, W., Lyu, S., Macaubas, C., Bunning, B., He, Z., Mellins, E., & Nadeau, K. C. (2021) · The Journal of Experimental Medicine · doi:10.1084/jem.20201793 · Cited by 28

Diverse roles of lung macrophages in the immune response to influenza A virus

Li, H., Wang, A., Zhang, Y., & Wei, F. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1260543 · Cited by 32

Temporal analysis of oxidative effects on the pulmonary inflammatory response in mice exposed to cigarette smoke

Campos, K. K. D., Manso, R. G., Gonçalves, E. G., Silva, M. E., de Lima, W. G., Menezes, C. A. D. S., & Bezerra, F. S. (2013) · Cellular Immunology · doi:10.1016/j.cellimm.2013.07.002 · Cited by 28

Abundance of Non-Polarized Lung Macrophages with Poor Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD)

Akata, K., Yamasaki, K., Filho, F. S. L., Yang, C., Takiguchi, H., Sahin, B., Whalen, B. A., Yang, C. W. T., Leung, J. M., Sin, D. D., et al. (2020) · Biomedicines · doi:10.3390/biomedicines8100398 · Cited by 27

Tanreqing Injection Attenuates Macrophage Activation and the Inflammatory Response via the lncRNA-SNHG1/HMGB1 Axis in Lipopolysaccharide-Induced Acute Lung Injury

Hu, C., Li, J., Tan, Y., Liu, Y., Bai, C., Gao, J., Zhao, S., Yao, M., Lu, X., Qiu, L., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.820718 · Cited by 27

Cell Origin and iNOS Function Are Critical to Macrophage Activation Following Acute Lung Injury

Golden, T., Venosa, A., & Gow, A. J. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.761496 · Cited by 26

Macrophage A2A Adenosine Receptors Are Essential to Protect from Progressive Kidney Injury

Truong, L. D., Trostel, J., McMahan, R. H., Chen, J., & García, G. (2016) · American Journal Of Pathology · doi:10.1016/j.ajpath.2016.06.017 · Cited by 26

MAP3K8 Regulates Cox-2–Mediated Prostaglandin E2 Production in the Lung and Suppresses Pulmonary Inflammation and Fibrosis

Ζαννίκου, Μ., Barbayianni, I., Fanidis, D., Grigorakaki, T., Vlachopoulou, E., Konstantopoulos, D., Fousteri, M. I., Nikitopoulou, I., Kotanidou, Α., Kaffe, E., et al. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.2000862 · Cited by 23

Explaining the polarized macrophage pool during murine allergic lung inflammation

Draijer, C., Florez‐Sampedro, L., Reker‐Smit, C., Post, E., van Dijk, F., & Melgert, B. N. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1056477 · Cited by 24

A far‐red fluorescent probe for flow cytometry and image‐based functional studies of xenobiotic sequestering macrophages

Keswani, R. K., Yoon, G. S., Sud, S., Stringer, K. A., & Rosania, G. R. (2015) · Cytometry Part A · doi:10.1002/cyto.a.22706 · Cited by 24

Collaboration Between Macrophages and Vaccine-Induced CD4+ T Cells Confers Protection Against Lethal Pseudomonas aeruginosa Pneumonia During Neutropenia

Kamei, A., Wu, W., Traficante, D. C., Koh, A. Y., van Rooijen, N., Pier, G. B., & Priebe, G. P. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis657 · Cited by 24

Mesenchymal stem cells exert their anti-asthmatic effects through macrophage modulation in a murine chronic asthma model

Kim, R. L., Bang, J., Kim, J., Mo, Y., Kim, Y., Lee, C. G., Elias, J. A., Kim, H. Y., & Kang, H. (2022) · Scientific Reports · doi:10.1038/s41598-022-14027-x · Cited by 24

Aquaporin 5 regulates cigarette smoke induced emphysema by modulating barrier and immune properties of the epithelium

Aggarwal, N. R., Chau, E. P., Garibaldi, B. T., Mock, J. R., Sussan, T. E., Rao, K., Rao, K. K., Menon, A. G., D’Alessio, F. R., Damarla, M., et al. (2013) · Tissue Barriers · doi:10.4161/tisb.25248 · Cited by 25

Porcine mononuclear phagocyte subpopulations in the lung, blood and bone marrow: dynamics during inflammation induced byActinobacillus pleuropneumoniae

Ondráčková, P., Nechvátalová, K., Kucerova, Z., Levá, L., Domı́nguez, J., & Faldyna, M. (2010) · Veterinary Research · doi:10.1051/vetres/2010035 · Cited by 23

Lung macrophages: current understanding of their roles in Ozone-induced lung diseases

Patial, S., & Saini, Y. (2020) · Critical Reviews in Toxicology · doi:10.1080/10408444.2020.1762537 · Cited by 23

Dynamic changes of mononuclear phagocytes in circulating, pulmonary alveolar and interstitial compartments in a mouse model of experimental silicosis

Xiang, G., Zhang, Y., Su, C., Ma, Y., Li, Y., Zhou, X., Wei, L., & Ji, W. (2016) · Inhalation Toxicology · doi:10.1080/08958378.2016.1188186 · Cited by 23

Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced disease

Wolf, A. I., Strauman, M. C., Mozdzanowska, K., Williams, K. L., Osborne, L. C., Shen, H., Liu, Q., Garlick, D., Artis, D., Hensley, S. E., et al. (2014) · Virology · doi:10.1016/j.virol.2014.06.019 · Cited by 22

Regulation of Macrophage and Dendritic Cell Responses by Their Lineage Precursors

Cortez‐Retamozo, V., Etzrodt, M., & Pittet, M. J. (2012) · Journal of Innate Immunity · doi:10.1159/000335733 · Cited by 22

Heterogeneity of Lung Mononuclear Phagocytes in Chronic Obstructive Pulmonary Disease

Lee, J. S. (2012) · Journal of Innate Immunity · doi:10.1159/000337434 · Cited by 21

Uncovering the core principles of the gut-lung axis to enhance innate immunity in the chicken

Saint-Martin, V., Quéré, P., Trapp, S., & Guabiraba, R. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.956670 · Cited by 22

The Protective Effects of Nutraceutical Components in Methotrexate-Induced Toxicity Models—An Overview

Marin, G.-E., Neag, M. A., Burlacu, C.-C., & Buzoianu, A. D. (2022) · Microorganisms · doi:10.3390/microorganisms10102053 · Cited by 20

Shaping of the alveolar landscape by respiratory infections and long-term consequences for lung immunity

Rodriguez-Rodriguez, L., Gillet, L., & Machiels, B. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1149015 · Cited by 23

In vivo hydroquinone exposure impairs MCP-1 secretion and monocyte recruitment into the inflamed lung

Shimada, A. L. B., Ribeiro, A. L. T., Bolonheis, S. M., Ferraz-de-Paula, V., Hebeda, C. B., & Farsky, S. H. P. (2012) · Toxicology · doi:10.1016/j.tox.2012.02.012 · Cited by 19

Thioaptamer targeted discoidal microparticles increase self immunity and reduce Mycobacterium tuberculosis burden in mice

Leonard, F., Ha, N. P., Sule, P., Alexander, J. F., Volk, D. E., Lokesh, G. L.-R., Liu, X., Cirillo, J. D., Gorenstein, D. G., Yuan, J., et al. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.09.038 · Cited by 20

Development and characterization of a lung-protective method of bone marrow transplantation in the mouse

Janssen, W. J., Muldrow, A., Kearns, M. T., Barthel, L., & Henson, P. M. (2010) · Journal of Immunological Methods · doi:10.1016/j.jim.2010.03.013 · Cited by 18

Selective and inducible targeting of CD11b+mononuclear phagocytes in the murine lung with hCD68-rtTA transgenic systems

McCubbrey, A. L., Barthel, L., Mould, K. J., Mohning, M. P., Redente, E. F., & Janssen, W. J. (2016) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00141.2016 · Cited by 17

Cadherin-11 Regulates Macrophage Development and Function

To, S., Chavula, T., Pedroza, M., Smith, J., & Agarwal, S. K. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.795337 · Cited by 17

Gastrointestinal microbiota: A predictor of COVID-19 severity?

Neag, M. A., Vulturar, D.-M., Gherman, D., Burlacu, C.-C., Todea, D. A., & Buzoianu, A. D. (2022) · World Journal of Gastroenterology · doi:10.3748/wjg.v28.i45.6328 · Cited by 19

Toll-like receptor 9 partially regulates lung inflammation induced following exposure to chicken barn air

Schneberger, D., Aulakh, G. K., Channabasappa, S., & Singh, B. (2016) · Journal of Occupational Medicine and Toxicology · doi:10.1186/s12995-016-0121-x · Cited by 16

Adenoviral vectors transduce alveolar macrophages in lung cancer models

Tippimanchai, D., Nolan, K., Poczobutt, J. M., Verzosa, G., Li, H. Y., Scarborough, H. A., Huang, J., Young, C. D., DeGregori, J. V., Nemenoff, R. A., et al. (2018) · OncoImmunology · doi:10.1080/2162402x.2018.1438105 · Cited by 16

Coinfection With Influenza A Virus and Klebsiella oxytoca: An Underrecognized Impact on Host Resistance and Tolerance to Pulmonary Infections

Lee, K. M., Morris‐Love, J., Cabral, D. J., Belenky, P. A., Opal, S. M., & Jamieson, A. M. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02377 · Cited by 15

Targeted Accumulation of Macrophages Induced by Microbeam Irradiation in a Tissue-Dependent Manner

Trappetti, V., Fazzari, J., Fernández-Palomo, C., Smyth, L. M. L., Potez, M., Shintani, N., Dietler, B. D. B., Martin, O. A., & Djonov, V. (2022) · Biomedicines · doi:10.3390/biomedicines10040735 · Cited by 15

Noninvasive assessment of the lung inflammation-fibrosis axis by targeted imaging of CMKLR1

Mannes, P. Z., Adams, T. S., Farsijani, S., Barnes, C. E., Latoche, J. D., Day, K. E., Nedrow, J. R., Ahangari, F., Kaminski, N., Lee, J. S., et al. (2024) · Science Advances · doi:10.1126/sciadv.adm9817 · Cited by 16

Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI)

Lin, C., Huang, T.-H., Yang, C., & Shi, C. (2021) · PLoS ONE · doi:10.1371/journal.pone.0248959 · Cited by 14

Thermostable Subunit Vaccines for Pulmonary Delivery: How Close Are We?

Foged, C. (2016) · Current Pharmaceutical Design · doi:10.2174/1381612822666160202141603 · Cited by 14

A mechanistic review of particle overload by titanium dioxide

Kawasaki, H. (2017) · Inhalation Toxicology · doi:10.1080/08958378.2018.1430192 · Cited by 14

Microenvironmental impact on lung cell homeostasis and immunity during infection

Tournier, J., & Mohamadzadeh, M. (2008) · Expert Review of Vaccines · doi:10.1586/14760584.7.4.457 · Cited by 14

Equine alveolar macrophages and monocyte-derived macrophages respond differently to an inflammatory stimulus

Kang, H., Lee, G. K. C., Bienzle, D., Arroyo, L. G., Sears, W., Lillie, B. N., & Beeler‐Marfisi, J. (2023) · PLoS ONE · doi:10.1371/journal.pone.0282738 · Cited by 15

Complex Involvement of Interleukin-26 in Bacterial Lung Infection

Che, K. F., Paulsson, M., Piersiala, K., Sax, J., Mboob, I., Rahman, M., Rekha, R. S., Säfholm, J., Mikael Adner, A., Bergman, P., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.761317 · Cited by 13

Pulmonary Macrophages

Laskin, D. L., Malaviya, R., & Laskin, J. D. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-404577-4.00032-1 · Cited by 14

Effects of Ischemia on Lung Macrophages

Moldobaeva, A., van Rooijen, N., & Wagner, E. M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0026716 · Cited by 13

Immunopathology of the Respiratory System

Greeley, M. A. (2017) · Molecular and integrative toxicology · doi:10.1007/978-3-319-47385-7_8 · Cited by 12

Tissue-resident macrophages exacerbate lung injury after remote sterile damage

Zhong, H., Ji, J., Zhuang, J., Xiong, Z., Xie, P., Liu, X., Zheng, J., Tian, W., Hong, X., & Tang, J. Y. (2024) · Cellular and Molecular Immunology · doi:10.1038/s41423-024-01125-1 · Cited by 11

Pulmonary mucosal dendritic cells in T-cell activation: implications for TB therapy

McCormick, S. M., Shaler, C. R., & Xing, Z. (2011) · Expert Review of Respiratory Medicine · doi:10.1586/ers.10.81 · Cited by 12

Flow cytometric analysis of the leukocyte landscape during bleomycin-induced lung injury and fibrosis in the rat

Kloth, C., Gruben, N., Ochs, M., Knudsen, L., & López-Rodríguez, E. (2019) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00176.2018 · Cited by 11

Dose-dependent immunomodulatory effects of metformin on human neonatal monocyte-derived macrophages

Wang, X., Liu, Y., Han, D., Zhong, J., Yang, C., & Chen, X. (2022) · Cellular Immunology · doi:10.1016/j.cellimm.2022.104557 · Cited by 10

Blood monocyte counts as a prognostic biomarker and predictor in Chinese patients with idiopathic pulmonary fibrosis

Zhang, X., Ren, Y., Xie, B., Ye, Q., Ban, C., Zhang, S., Zhu, M., Liu, Y., Wang, S., Geng, J., et al. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.955125 · Cited by 8

Immunopathological Mechanisms of Bird-Related Hypersensitivity Pneumonitis

Sánchez‐Díez, S., Cruz, M. J., de Homdedeu, M., Ojanguren, Í., Mesones, C. E. R., Sansano, I., & Muñoz, X. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032884 · Cited by 8

Monocyte Differentiation Is Controlled by MyD88 After Mouse Orthotopic Lung Transplantation

Sugimoto, S., Lin, X.-J., Okazaki, M., LAI, J. Z., Tietjens, J. R., Huang, H. J., Patterson, G. A., Krupnick, A. S., Kreisel, D., & Gelman, A. E. (2009) · Transplantation Proceedings · doi:10.1016/j.transproceed.2008.09.064 · Cited by 8

Tissue‐resident innate lymphoid cells in asthma

Wang, X., Kong, Y., Zheng, B., Zhao, X., Zhao, M., Wang, B., Liu, C., & Yan, P. (2023) · The Journal of Physiology · doi:10.1113/jp284686 · Cited by 10

Dudleya brittonii extract promotes survival rate and M2-like metabolic change in porcine 3D4/31 alveolar macrophages

Kim, H., Jeon, E. H., Park, B., & Kim, S. (2019) · Asian-Australasian Journal of Animal Sciences · doi:10.5713/ajas.19.0251 · Cited by 7

RPTPε promotes M2-polarized macrophage migration through ROCK2 signaling and podosome formation

Lapointe, F., Turcotte, S., Roy, J., Bissonnette, É. Y., Rola‐Pleszczynski, M., & Staňková, J. (2019) · Journal of Cell Science · doi:10.1242/jcs.234641 · Cited by 7

Host Pathogen Biology for AirborneMycobacterium tuberculosis

Arnett, E., Krishnan, N., Robertson, B. D., & Schlesinger, L. S. (2016) · Wiley eBooks · doi:10.1002/9781118943182.ch2 · Cited by 7

Immunobiology of pulmonary fibrosis

Bindu, S., Yasmin, H., Barman, U., Pandit, S., Masmoudi, K., & Kishore, U. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1708716 · Cited by 6

Nasal Priming with Lactobacillus rhamnosus CRL1505 Stimulates Mononuclear Phagocytes of Immunocompromised Malnourished Mice: Improvement of Respiratory Immune Response

Barbieri, N., Salva, S., Herrera, M., Villena, J., & Alvarez, S. (2019) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-019-09551-8 · Cited by 6

Distribution of macrophages and T cells in syngrafts and allografts after experimental rat lung transplantation

Jungraithmayr, W., İnci, İ., Bain, M., Hillinger, S., Korom, S., & Weder, W. (2009) · Immunobiology · doi:10.1016/j.imbio.2009.04.003 · Cited by 6

The pulmonary interstitial cell as immediate precursor of the alveolar macrophage.

Bowden, D. H., & Adamson, I. Y. R. (1972) · PubMed · Cited by 90

Evidence for the pulmonary origin of alveolar macrophages

Tarling, J. D., & Coggle, J. E. (1982) · Cell Proliferation · doi:10.1111/j.1365-2184.1982.tb01064.x · Cited by 38

The origin, kinetics, and characteristics of pulmonary macrophages in the normal steady state

Blussi, A., Oud, V., Alblas, & Furth, R. V. (1979)

Human CD116+ fetal liver progenitors migrate to the perinatal lung and give rise to alveolar macrophages in vivo

Evren, E., Ringqvist, E. E., Doisne, J., Thaller, A., Sleiers, N., Flavell, R. A., Santo, J. P. D., & Willinger, T. (2022) · 03.02 - Airway cell biology and immunopathology · doi:10.1183/13993003.congress-2022.lsc-0015

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

Guilliams, M., de Kleer, I., Henri, S., Post, S., Vanhoutte, L., Prijck, S. D., Deswarte, K., MALISSEN, B., Hammad, H., & Lambrecht, B. N. (2013) · The Journal of Experimental Medicine · doi:10.1084/jem.20131199 · Cited by 1,342