A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

Schoenberger, S. P., Toes, R. E. M., van der Voort, E. I. H., Offringa, R., & Melief, C. J. M. (1998) · Nature · doi:10.1038/31002 · Cited by 2,615 · see citing works

Immunological memory and protective immunity: understanding their relation

Ahmed, R., & Gray, D. (1996) · Science · doi:10.1126/science.272.5258.54 · Cited by 1,775 · see citing works

Adapting to obesity with adipose tissue inflammation

Reilly, S. M., & Saltiel, A. R. (2017) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2017.90 · Cited by 1,204 · see citing works

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

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Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

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Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

Shalapour, S., Lin, X.-J., Bastian, I. N., Brain, J., Burt, A. D., Aksenov, A. A., Vrbanac, A. F., Li, W., Perkins, A., Matsutani, T., et al. (2017) · Nature · doi:10.1038/nature24302 · Cited by 589 · see citing works

B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile

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B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo

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Segmented filamentous bacteria antigens presented by intestinal dendritic cells drive mucosal Th17 cell differentiation

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T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.

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CD4 ⁺ T cells mediate antibody-independent acquired immunity to pneumococcal colonization

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Microbial metabolites control the thymic development of mucosal-associated invariant T cells

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Augmentation of T cell levels and responses induced by androgen deprivation

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Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection

Loke, P., Gallagher, I., Nair, M. G., Zang, X., Brombacher, F., Mohrs, M., Allison, J. P., & Allen, J. E. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.6.3926 · Cited by 274 · see citing works

Lung macrophages serve as obligatory intermediate between blood monocytes and alveolar macrophages

Landsman, L., & Jung, S. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.6.3488 · Cited by 258 · see citing works

Adipose natural regulatory B cells negatively control adipose tissue inflammation

Nishimura, S., Manabe, I., Takaki, S., Nagasaki, M., Otsu, M., Yamashita, H., Sugita, J., Yoshimura, K., Eto, K., Komuro, I., et al. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.09.017 · Cited by 251 · see citing works

<i>Aspergillus fumigatus</i> : Principles of Pathogenesis and Host Defense

Hohl, T. M., & Feldmesser, M. (2007) · Eukaryotic Cell · doi:10.1128/ec.00274-07 · Cited by 237 · see citing works

IgA production without μ or δ chain expression in developing B cells

Macpherson, A. J. S., Lamarre, A., McCoy, K., Harriman, G. R., Odermatt, B., Dougan, G., Hengartner, H., & Zinkernagel, R. M. (2001) · Nature Immunology · doi:10.1038/89775 · Cited by 223 · see citing works

Resurrection of endogenous retroviruses in antibody-deficient mice

Young, G. R., Eksmond, U., Salcedo, R., Alexopoulou, L., Stoye, J. P., & Kassiotis, G. (2012) · Nature · doi:10.1038/nature11599 · Cited by 215 · see citing works

Microbiota‐Driven Activation of Intrahepatic B Cells Aggravates NASH Through Innate and Adaptive Signaling

Barrow, F., Khan, S., Fredrickson, G., Wang, H., Dietsche, K., Parthiban, P., Robert, S., Kaiser, T., Winer, S., Herman, A., et al. (2021) · Hepatology · doi:10.1002/hep.31755 · Cited by 210 · see citing works

Adaptive immune determinants of viral clearance and protection in mouse models of SARS-CoV-2

Israelow, B., Mao, T., Klein, J., Song, E., Menasche, B., Omer, S. B., & Iwasaki, A. (2021) · Science Immunology · doi:10.1126/sciimmunol.abl4509 · Cited by 189 · see citing works

Adaptive immune determinants of viral clearance and protection in mouse models of SARS-CoV-2

Israelow, B., Mao, T., Klein, J., Song, E., Menasche, B., Omer, S. B., & Iwasaki, A. (2021) · doi:10.1101/2021.05.19.444825 · Cited by 189 · see citing works

Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models

Rapti, K., Louis-Jeune, V., Kohlbrenner, E., Ishikawa, K., Ladage, D., Zolotukhin, S., Hajjar, R. J., & Weber, T. (2012) · Molecular Therapy · doi:10.1038/mt.2011.177 · Cited by 170 · see citing works

Limited Role of Antibody in Clearance of <i>Streptococcus pneumoniae</i> in a Murine Model of Colonization

McCool, T. L., & Weiser, J. N. (2004) · Infection and Immunity · doi:10.1128/iai.72.10.5807-5813.2004 · Cited by 153 · see citing works

The role of Bruton’s tyrosine kinase in autoimmunity and implications for therapy

Crofford, L. J., Nyhoff, L. E., Sheehan, J. H., & Kendall, P. L. (2016) · Expert Review of Clinical Immunology · doi:10.1586/1744666x.2016.1152888 · Cited by 142 · see citing works

An intact immune system is required for the anticancer activities of histone deacetylase inhibitors

West, A. C., Mattarollo, S. R., Shortt, J., Cluse, L. A., Christiansen, A. J., Smyth, M. J., & Johnstone, R. W. (2013) · Cancer Research · doi:10.1158/0008-5472.can-13-0890 · Cited by 137 · see citing works

Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling

Ying, W., Wollam, J., Ofrecio, J. M., Bandyopadhyay, G., El Ouarrat, D., Lee, Y. S., Oh, D. Y., Li, P., Osborn, O., & Olefsky, J. M. (2017) · Journal of Clinical Investigation · doi:10.1172/jci90350 · Cited by 128 · see citing works

TBL1XR1 mutations drive extranodal lymphoma by inducing a pro-tumorigenic memory fate

Venturutti, L., Teater, M., Zhai, A., Chadburn, A., Babiker, L., Kim, D., Béguelin, W., Lee, T. C., Kim, Y., Chin, C. R., et al. (2020) · Cell · doi:10.1016/j.cell.2020.05.049 · Cited by 127 · see citing works

Role of PI3K in the generation and survival of B cells

Werner, M., Hobeika, E., & Jumaa, H. (2010) · Immunological Reviews · doi:10.1111/j.1600-065x.2010.00934.x · Cited by 122 · see citing works

Local Production of Osteoprotegerin by Osteoblasts Suppresses Bone Resorption

Cawley, K. M., Bustamante-Gomez, N. C., Guha, A. G., MacLeod, R. S., Xiong, J., Gubrij, I., Liu, Y., Mulkey, R., Palmieri, M., Thostenson, J. D., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108052 · Cited by 114 · see citing works

Liver Fibrosis Occurs Through Dysregulation of MyD88-Dependent Innate B-Cell Activity

Thapa, M., Chinnadurai, R., Velazquez, V. M., Tedesco, D., Elrod, E., Han, J., Sharma, P., Ibegbu, C., Gewirtz, A., Anania, F., et al. (2015) · Hepatology · doi:10.1002/hep.27761 · Cited by 101 · see citing works

B cell depletion or absence does not impede anti-tumor activity of PD-1 inhibitors

Damsky, W., Jilaveanu, L., Turner, N., Perry, C., Zito, C., Tomayko, M., Leventhal, J., Herold, K., Meffre, E., Bosenberg, M., et al. (2019) · Journal for ImmunoTherapy of Cancer · doi:10.1186/s40425-019-0613-1 · Cited by 78 · see citing works

ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis

Nalkurthi, C., Schroder, W. A., Melino, M., Irvine, K. M., Nyuydzefe, M., Chen, W., Liu, J., Teng, M. W. L., Hill, G. R., Bertolino, P., et al. (2022) · JHEP Reports · doi:10.1016/j.jhepr.2021.100386 · Cited by 75 · see citing works

Transient Immunomodulation Allows Repeated Injections of AAV1 and Correction of Muscular Dystrophy in Multiple Muscles

Lorain, S., Gross, D.-A., Goyenvalle, A., Danos, O., Davoust, J., & Garcia, L. (2008) · Molecular Therapy · doi:10.1038/sj.mt.6300377 · Cited by 62 · see citing works

Circumventing cellular immunity by miR142-mediated regulation sufficiently supports rAAV-delivered OVA expression without activating humoral immunity

Xiao, Y., Muhuri, M., Li, S., Qin, W., Xu, G., Luo, L., Li, J., Letizia, A. J., Wang, S. K., Chan, Y. K., et al. (2019) · JCI Insight · doi:10.1172/jci.insight.99052 · Cited by 53 · see citing works

B lymphocytes are critical for lung fibrosis control and prostaglandin E2 regulation in IL-9 transgenic mice

Arras, M., Louahed, J., Simoen, V., Barbarin, V., Misson, P., van den Brûle, S., Delos, M., Knoops, L., Renauld, J.-C., Lison, D., et al. (2006) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2004-0383oc · Cited by 46 · see citing works

Phospholipase Cγ2 Provides Survival Signals via Bcl2 and A1 in Different Subpopulations of B Cells

Wen, R., Chen, Y., Xue, L., Schuman, J., Yang, S., Morris, S. W., & Wang, D. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307318200 · Cited by 41 · see citing works

Phospholipase Cγ2 Contributes to Light-Chain Gene Activation and Receptor Editing

Bai, L., Chen, Y., He, Y., Dai, X., Lin, X., Wen, R., & Wang, D. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.02273-06 · Cited by 22 · see citing works

Is there a role for B cells in Alzheimer's disease?

Charavner, E.-L., Fillatreau, S., & El Behi, M. (2026) · Cellular Immunology · doi:10.1016/j.cellimm.2026.105154