Cognitive Processing Therapy for Posttraumatic Stress Disorder Delivered to Rural Veterans via Telemental Health: A Randomized Noninferiority Clinical Trial
Abstract
OBJECTIVE: To compare clinical and process outcomes of cognitive processing therapy-cognitive only version (CPT-C) delivered via videoteleconferencing (VTC) to in-person in a rural, ethnically diverse sample of veterans with posttraumatic stress disorder (PTSD). METHOD: A randomized clinical trial with a noninferiority design was used to determine if providing CPT-C via VTC is effective and "as good as" in-person delivery. The study took place between March 2009 and June 2013. PTSD was diagnosed per DSM-IV. Participants received 12 sessions of CPT-C via VTC (n = 61) or in-person (n = 64). Assessments were administered at baseline, midtreatment, immediately posttreatment, and 3 and 6 months posttreatment. The primary clinical outcome was posttreatment PTSD severity, as measured by the Clinician-Administered PTSD Scale. RESULTS: Clinical and process outcomes found VTC to be noninferior to in-person treatment. Significant reductions in PTSD symptoms were identified at posttreatment (Cohen d = 0.78, P < .05) and maintained at 3- and 6-month follow-up (d = 0.73, P < .05 and d = 0.76, P < .05, respectively). High levels of therapeutic alliance, treatment compliance, and satisfaction and moderate levels of treatment expectancies were reported, with no differences between groups (for all comparisons, F < 1.9, P > .17). CONCLUSIONS: Providing CPT-C to rural residents with PTSD via VTC produced outcomes that were "as good as" in-person treatment. All participants demonstrated significant reductions in PTSD symptoms posttreatment and at follow-up. Results indicate that VTC can offer increased access to specialty mental health care for residents of rural or remote areas. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT00879255.
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A handful of studies have documented the non-inferiority of VCP when compared to gold-standard treatments.
“Moreover, a handful of studies have documented the non-inferiority of VCP when compared to gold-standard treatments [34,35,36,37,38].”
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“Thus, several major clinical trials were commissioned to assess the effectiveness of PE and CPT alone or in combination with drugs approved for treating PTSD in combat veterans suffering from PTSD who were still serving on active duty.”
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“The few studies that have more specifically evaluated videoconference group CBT have primarily focused on PTSD, with results demonstrating outcomes similar to face-to-face CBT groups.(30,43-45) Surprisingly, there is little research on videoconference CBT groups for anxiety disorders, the most prevalent psychiatric di…”
BackgroundFully remote intensive trauma-focused treatment for PTSD and Complex PTSD
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“The present results are in accordance with other studies showing that remotely administered psychotherapy is a useful, e ff ective and an e ffi cient treat-ment alternative (Acierno et al., 2016, 2017; Germain et al., 2009; Morland et al., 2014, 2020; Tuerk et al., 2010; Turgoose et al., 2018).”
BackgroundResultState of the Science of Cognitive Processing Therapy
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“…samples, veterans, and service members (e.g., Dondanville et al., 2022; Monson et al., 2006; Resick et al., 2017) in outpatient and residential settings (e.g., Walter et al., 2014); and when delivered in-person, in-home, and via telehealth (e.g., Morland et al., 2014; Peterson et al., 2022).”
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Kuhn, E., & Owen, J. E. (2020) · Current Treatment Options in Psychiatry · doi:10.1007/s40501-020-00207-x · Cited by 34 · see citing works
Lobban, J., & Murphy, D. (2019) · The Arts in Psychotherapy · doi:10.1016/j.aip.2018.11.011 · Cited by 35 · see citing works
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Predictors of Treatment Discontinuation During Prolonged Exposure for PTSD
Grös, D. F., Allan, N. P., Lancaster, C. L., Szafranski, D. D., & Acierno, R. E. (2017) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s135246581700039x · Cited by 32 · see citing works
“Survival analyses should be completed in similarly powered evidence-based psychotherapy telehealth studies to determine if this finding replicates (Acierno et al., 2016; Morland et al., 2014).”
BackgroundEffectiveness of PTSD telehealth treatment in a VA clinical sample.
Wierwille, J. L., Pukay‐Martin, N. D., Chard, K. M., & Klump, M. C. (2016) · Psychological Services · doi:10.1037/ser0000106 · Cited by 31 · see citing works
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“We drew data for this study from the baseline assessments of a clinical trial evaluating the effectiveness of the telehealth modality for delivering cognitive processing therapy [27] to combat Veterans with PTSD [28]; this included baseline data from a pilot cohort [29].”
Self-citationComparative Efficacy of Online vs. Face-to-Face Group Interventions: A Systematic Review
Rafieifar, M., Hanbidge, A. S., Lorenzini, S. B., & Macgowan, M. J. (2024) · Research on Social Work Practice · doi:10.1177/10497315241236966 · Cited by 32 · see citing works
Psychotherapy for PTSD: An evidence-based guide to a theranostic approach to treatment
Goodnight, J. R. M., Ragsdale, K. A., Rauch, S. A. M., & Rothbaum, B. O. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.05.006 · Cited by 28 · see citing works
Videoconferencing Psychotherapy in the Public Sector: Synthesis and Model for Implementation
Muir, S. D., de Boer, K., Thomas, N., Seabrook, E., Nedeljkovic, M., & Meyer, D. (2020) · JMIR Mental Health · doi:10.2196/14996 · Cited by 33 · see citing works
“Therefore, it is understandable that clinicians may hold reservations about using such approaches with VCP, despite studies demonstrating VCP to be safe and effective when using interventions, such as cognitive behavioral therapy and Prolonged Exposure for posttraumatic stress disorder populations [63,64].”
MethodAn intensive outpatient treatment program for combat-related PTSD: Trauma Management Therapy
Beidel, D. C., Stout, J. W., Neer, S. M., Frueh, B. C., & Lejuez, C. W. (2017) · Bulletin of the Menninger Clinic · doi:10.1521/bumc.2017.81.2.107 · Cited by 26 · see citing works
“In some cases, explanations suggest that these other behaviors are affected by PE and CPT; however, with the exception of depression and general anxiety, the outcome assessment batteries rarely, if ever, included specific assessment of behaviors such as anger, social isolation, guilt, or occupational adjustment.”
BackgroundInfluentialSelf-citationBauer, A., Amspoker, A. B., Fletcher, T. L., Jackson, C., Jacobs, A., Hogan, J., Shammet, R., Speicher, S., Lindsay, J. A., & Cloître, M. (2021) · European Journal of Psychotraumatology · doi:10.1080/20008198.2020.1860357 · Cited by 28 · see citing works
Brief treatment for PTSD: A non-inferiority trial
Sloan, D., Marx, B. P., & Resick, P. (2016) · Contemporary Clinical Trials · doi:10.1016/j.cct.2016.04.003 · Cited by 21 · see citing works
“, CPT) is equally efficacious when delivered in person versus remote video teleconferencing [25,26].”
BackgroundSelf-citationJohnson, E., & Possemato, K. (2019) · Psychological Trauma Theory Research Practice and Policy · doi:10.1037/tra0000461 · Cited by 29 · see citing works
Shreck, E., Nehrig, N., Schneider, J. A., Palfrey, A., Buckley, J., Jordan, B., Ashkenazi, S., Wash, L. K., Baer, A. L., & Chen, C. K. (2020) · Rural Mental Health · doi:10.1037/rmh0000129 · Cited by 26 · see citing works
Bumgarner, D. J., Polinsky, E. J., Herman, K. G., Fordiani, J., Lewis, C. P., Hansen, S. K., Rutschman, R. L., Bonnell, M. A., & Cardin, S. A. (2017) · Rural Mental Health · doi:10.1037/rmh0000078 · Cited by 26 · see citing works
“Clinical video telehealth was found to be comparable to face-to-face treatment (Morland et al., 2015; Ziemba et al., 2014), to increase access to evidence-based psychotherapies for PTSD (Lindsay et al.”
BackgroundNobleza, D., Hagenbaugh, J., Blue, S., Stepchin, A., Vergare, M. J., & Pohl, C. A. (2018) · Journal of College Student Psychotherapy · doi:10.1080/87568225.2018.1491362 · Cited by 28 · see citing works
“…Hilty et al., 2013; Hilty, Marks, Urness, Yellowlees, & Nesbitt, 2004; Shore, 2013) and telecounseling (Bashshur et al., 2016; Hilty et al., 2013; Morland et al., 2014; Shingleton, Richards, & Thompson-Brenner, 2013; Simpson, 2009) for a variety of mental health problems, and the use of…”
BackgroundBrowne, K. C., Chen, J. A., Hundt, N. E., Hudson, T. J., Grubbs, K. M., & Fortney, J. C. (2019) · Psychological Services · doi:10.1037/ser0000375 · Cited by 26 · see citing works
“Only one veteran in the CPT group indicated that non-attendance was related to the interactive video technology, which matches prior studies that have found comparable treatment satisfaction for in person and clinical video teleconferencing (Morland et al., 2014; Yuen et al., 2015).”
ResultTelehealth Technologies in Evidence-Based Psychotherapy
Wangelin, B. C., Szafranski, D. D., & Grös, D. F. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802075-3.00005-x · Cited by 26 · see citing works
Trauma-focused treatment for comorbid post-traumatic stress and substance use disorder
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Usual Care for Rural Veterans With Posttraumatic Stress Disorder
Grubbs, K. M., Fortney, J. C., Kimbrell, T. A., Pyne, J. M., Hudson, T. J., Robinson, D., Moore, W. M., Custer, P., Schneider, R., & Schnurr, P. P. (2017) · The Journal of Rural Health · doi:10.1111/jrh.12230 · Cited by 24 · see citing works
Rasmusson, A. M., Pineles, S. L., Brown, K. D., & Pinna, G. (2021) · Journal of Neuroendocrinology · doi:10.1111/jne.13062 · Cited by 24 · see citing works
Watkins, L. L., LoSavio, S. T., Calhoun, P. S., Resick, P. A., Sherwood, A., Coffman, C. J., Kirby, A. C., Beaver, T. A., Dennis, M. F., & Beckham, J. C. (2023) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2023.111351 · Cited by 28 · see citing works
Self-citationPractical issues in delivery of clinician-to-patient telemental health in an academic medical center
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“Additional published experience on virtual visits for various patient populations since 2013 (see Table 1) includes the following: treatment of attention-deficit/hyperactivity disorder (ADHD) in children; treatment of posttraumatic stress disorder (PTSD) (even during actual deployment/in war zones); home-based, outpat…”
BackgroundChen, J. A., Fortney, J. C., Bergman, H. E., Browne, K. C., Grubbs, K. M., Hudson, T. J., & Raue, P. J. (2019) · Psychological Services · doi:10.1037/ser0000329 · Cited by 26 · see citing works
“Because several studies have found no difference in therapeutic alliance between telemedicine-delivered and in-person CPT (Morland et al., 2014), psychotherapy for depression (Preschl, Maercker, & Wagner, 2011), or psychotherapy for anxiety disorders (Klein, Richards, & Austin, 2006), we did not…”
BackgroundInfluentialBouchard, S., Dugas, M. J., Belleville, G., Langlois, F., Gosselin, P., Robillard, G., Corno, G., & Marchand, A. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11195924 · Cited by 21 · see citing works
Valentine, L. M., Donofry, S. D., Broman, R. B., Smith, E. R., Rauch, S. A., & Sexton, M. B. (2020) · Journal of Telemedicine and Telecare · doi:10.1177/1357633x19832419 · Cited by 21 · see citing works
Galovski, T. E., Nixon, R. D. V., & Kehle‐Forbes, S. (2024) · Journal of Traumatic Stress · doi:10.1002/jts.23073 · Cited by 23 · see citing works
- Authors
- Morland, L. A., Mackintosh, M.-A., Greene, C. J., Rosen, C. S., Chard, K. M., Resick, P., & Frueh, B. C.
- Affiliations
- National Center for PTSD (US)
- VA Palo Alto Health Care System (US)
- Cincinnati VA Medical Center (US)
- VA Boston Healthcare System (US)
- University of Hawaii at Hilo (US)
- ORCID
- Venue
- The Journal of Clinical Psychiatry
- Publisher
- Physicians Postgraduate Press, Inc
- Published
- 2014-05-15
- Volume
- 75
- Issue
- 05
- Pages
- 470-476
- ISSN
- 0160-6689 (ISSN-L)
- OpenAlex
- W2088885347
- Cited by
- 234
- References
- 0
- Citations by year
- 2026: 6 · 2025: 16 · 2024: 12 · 2023: 13 · 2022: 36 · 2021: 23 · 2020: 22 · 2019: 25 · 2018: 21 · 2017: 20 · 2016: 17 · 2015: 22 · 2014: 1
- FWCI
- 23.60
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- cognitive processing therapy, post-traumatic stress disorder, veterans, rural mental health services, telemental health, non-inferiority, access to specialist care, therapeutic relationship, medication adherence, treatment satisfaction, treatment expectancy
- MeSH terms
- Adult, Humans, Male, Middle Aged, Prospective Studies, Psychotherapy, Group, Rural Population, Severity of Illness Index, Stress Disorders, Post-Traumatic, United States, Veterans, Cognitive Behavioral Therapy, Treatment Outcome, Telemedicine
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