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Cited by 77

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Liposomal‐encapsulated ascorbic acid: Influence on vitamin C bioavailability and capacity to protect against ischemia–reperfusion injury

Davis, Janelle L., Paris, Hunter L., Beals, Joseph W., Binns, Scott E., Giordano, Gregory R., Scalzo, Rebecca L., Schweder, Melani M., Blair, Emek, Bell, Christopher·2016·Nutrition and Metabolic Insights
DOI 10.4137/nmi.s39764PMC PMC4915787
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Abstract

Intravenous administration of vitamin C has been shown to decrease oxidative stress and, in some instances, improve physiological function in adult humans. Oral vitamin C administration is typically less effective than intravenous, due in part to inferior vitamin C bioavailability. The purpose of this study was to determine the efficacy of oral delivery of vitamin C encapsulated in liposomes. On 4 separate randomly ordered occasions, 11 men and women were administered an oral placebo, or 4 g of vitamin C via oral, oral liposomal, or intravenous delivery. The data indicate that oral delivery of 4 g of vitamin C encapsulated in liposomes (1) produces circulating concentrations of vitamin C that are greater than unencapsulated oral but less than intravenous administration and (2) provides protection from ischemia–reperfusion-mediated oxidative stress that is similar to the protection provided by unencapsulated oral and intravenous administrations.

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  • Nanoparticles can deliver hydrophilic and hydrophobic therapeutic agents, enhance absorption, protect molecules from stomach acids, and reduce toxic side effects.

    “nanoparticles have the ability to deliver hydrophilic and hydrophobic therapeutic agents, enhance absorption, protect various molecules from stomach acids, and reduce toxic side effects. 27 , 28”

    From Three Tiers to biological escape velocity: The quest to outwit aging (2022) · cites this paper as [28]

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Research works printed but not linked: 43

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Metadata

Authors
Davis, J. L., Paris, H. L., Beals, J. W., Binns, S. E., Giordano, G. R., Scalzo, R. L., Schweder, M. M., Blair, E., & Bell, C.
Affiliations
  • Department of Health and Exercise Science, Colorado State University, Fort Collins, CO, USA.
  • Empirical Labs, Fort Collins, Colorado, USA.
Venue
Nutrition and Metabolic Insights
Publisher
SAGE Publications
Published
2016-01
Volume
9
ISSN
1178-6388
DOI
10.4137/nmi.s39764
PMC
PMC4915787
Cited by
77
References
3
Language
en
Licence
journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)

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