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Adult-onset CNS myelin sulfatide deficiency is sufficient to cause Alzheimer’s disease-like neuroinflammation and cognitive impairment

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COVID-19 and Alzheimer’s Disease

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Mechanistic Link between Vitamin B12 and Alzheimer’s Disease

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Microglia and Astrocytes in Alzheimer’s Disease: Significance and Summary of Recent Advances

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Oligodendrocyte progenitor cells in Alzheimer's disease: from physiology to pathology

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Mechanistic Link between Vitamin B12 and Alzheimer’s Disease

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Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination

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Current Insights Into Oligodendrocyte Metabolism and Its Power to Sculpt the Myelin Landscape

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Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice

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Myelin in Alzheimer’s disease: culprit or bystander?

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Clemastine Ameliorates Myelin Deficits via Preventing Senescence of Oligodendrocytes Precursor Cells in Alzheimer’s Disease Model Mouse

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Oligodendroglia are emerging players in several forms of learning and memory

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Role of Neuron and Glia in Alzheimer’s Disease and Associated Vascular Dysfunction

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A New Hypothesis for Alzheimer’s Disease: The Lipid Invasion Model

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The role of glial autophagy in Alzheimer’s disease

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Cdk5-p25 as a key element linking amyloid and tau pathologies in Alzheimer's disease: Mechanisms and possible therapeutic interventions

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Potential neurobiological links between social isolation and Alzheimer's disease risk

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Tlr7 drives sex differences in age- and Alzheimer’s disease–related demyelination

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Noninvasive Gamma Sensory Stimulation May Reduce White Matter and Myelin Loss in Alzheimer’s Disease

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The role of polyunsaturated fatty acids in neuronal signaling in depression and cognitive processes

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Myelin repair in Alzheimer’s disease: a review of biological pathways and potential therapeutics

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Proteomic analysis of human hippocampal subfields provides new insights into the pathogenesis of Alzheimer’s disease and the role of glial cells

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Association of autoimmune diseases with Alzheimer's disease: A mendelian randomization study

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1700 nm optical coherence microscopy enables minimally invasive, label-free, in vivo optical biopsy deep in the mouse brain

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A multi-scale model explains oscillatory slowing and neuronal hyperactivity in Alzheimer’s disease

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Neuronal loss and microgliosis are restricted to the core of Aβ deposits in mouse models of Alzheimer's disease

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Mild Traumatic Brain Injury Results in Significant and Lasting Cortical Demyelination

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Disrupting Neurons and Glial Cells Oneness in the Brain—The Possible Causal Role of Herpes Simplex Virus Type 1 (HSV-1) in Alzheimer’s Disease

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Role of Demyelination in the Persistence of Neurological and Mental Impairments after COVID-19

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Revealing the Molecular Mechanisms of Alzheimer’s Disease Based on Network Analysis

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Tanshinone IIA attenuates Aβ-induced neurotoxicity by down-regulating COX-2 expression and PGE2 synthesis via inactivation of NF-κB pathway in SH-SY5Y cells

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White matter injury, cholesterol dysmetabolism, and APP/Abeta dysmetabolism interact to produce Alzheimer’s disease (AD) neuropathology: A hypothesis and review

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Cortical myelin profile variations in healthy aging brain: A T1w/T2w ratio study

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Associations between diffusion MRI microstructure and cerebrospinal fluid markers of Alzheimer's disease pathology and neurodegeneration along the Alzheimer's disease continuum

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Vitamin B12 Attenuates Changes in Phospholipid Levels Related to Oxidative Stress in SH-SY5Y Cells

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Alternative Targets to Fight Alzheimer’s Disease: Focus on Astrocytes

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Disease-Associated Oligodendrocyte: New Player in Alzheimer's Disease and CNS Pathologies

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TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice

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Molecular Insights into Cell Type-specific Roles in Alzheimer’s Disease: Human Induced Pluripotent Stem Cell-based Disease Modelling

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The Current Challenges for Drug Discovery in CNS Remyelination

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Co-Ultramicronized Palmitoylethanolamide/Luteolin Restores Oligodendrocyte Homeostasis via Peroxisome Proliferator-Activated Receptor-α in an In Vitro Model of Alzheimer’s Disease

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Regional contribution of vascular dysfunction in white matter dementia: clinical and neuropathological insights

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New Insights into the Molecular Interplay between Human Herpesviruses and Alzheimer’s Disease—A Narrative Review

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Cdk5-mediated oligodendrocyte myelin breakdown and neuroinflammation: Implications for the link between Type 2 Diabetes and Alzheimer's disease

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Mdivi-1 Rescues Memory Decline in Scopolamine-Induced Amnesic Male Mice by Ameliorating Mitochondrial Dynamics and Hippocampal Plasticity

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Scalable mapping of myelin and neuron density in the human brain with micrometer resolution

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The contribution of DNA methylation to the (dys)function of oligodendroglia in neurodegeneration

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Radiation Therapy in Alzheimer's Disease: A Systematic Review

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Evaluating EEG complexity and spectral signatures in Alzheimer’s disease and frontotemporal dementia: evidence for rostrocaudal asymmetry

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Targeted delivery of BACE1 siRNA for synergistic treatment of Alzheimer's disease

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Key brain cell interactions and contributions to the pathogenesis of Alzheimer’s disease

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Prophylactic effects of apigenin against hyperglycemia-associated amnesia via activation of the Nrf2/ARE pathway in zebrafish

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Cortical amyloid-beta burden is associated with changes in intracortical myelin in cognitively normal older adults

Fernandez-Alvarez, M., Atienza, M., & Cantero, J. L. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02420-7 · Cited by 18

Mitochondrial Connexins and Mitochondrial Contact Sites with Gap Junction Structure

Cetin-Ferra, S., Francis, S., Cooper, A. T., Neikirk, K., Marshall, A. G., Hinton, A. O., Jr., & Murray, S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24109036 · Cited by 15

Investigating brain–gut microbiota dynamics and inflammatory processes in an autistic-like rat model using MRI biomarkers during childhood and adolescence

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WWOX and metabolic regulation in normal and pathological conditions

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Deep Imaging to Dissect Microvascular Contributions to White Matter Degeneration in Rodent Models of Dementia

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Exacerbation of Pre-existing Neurological Symptoms With COVID-19 in Patients With Chronic Neurological Diseases: An Updated Systematic Review

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Rethinking neurodegenerative diseases: neurometabolic concept linking lipid oxidation to diseases in the central nervous system

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Enhancing axonal myelination in seniors: A review exploring the potential impact cannabis has on myelination in the aged brain

Murray, C. J., Vecchiarelli, H. A., & Tremblay, M. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1119552 · Cited by 12

Alzheimer’s disease and multiple sclerosis: a possible connection through the viral demyelinating neurodegenerative trigger (vDENT)

Boukhvalova, M. S., Kastrukoff, L. F., & Blanco, J. C. G. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1204852 · Cited by 11

Central nervous system sulfatide deficiency as a causal factor for bladder disorder in Alzheimer's disease

He, S., Qiu, S., Pan, M., Palavicini, J. P., Wang, H., Li, X., Bhattacharjee, A., Barannikov, S., Bieniek, K. F., Dupree, J. L., et al. (2023) · Clinical and Translational Medicine · doi:10.1002/ctm2.1332 · Cited by 11

Uridine as a Regulator of Functional and Ultrastructural Changes in the Brain of Rats in a Model of 6-OHDA-Induced Parkinson’s Disease

Uspalenko, N. I., Mosentsov, A. A., Khmil, N. V., Pavlik, L. L., Belosludtseva, N. V., Khunderyakova, N. V., Shigaeva, M. I., Medvedeva, V. P., Malkov, A., Kitchigina, V. F., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241814304 · Cited by 11

Dunalialla salina microalgae and its isolated zeaxanthin mitigate age-related dementia in rats: Modulation of neurotransmission and amyloid-β protein

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Hippeastrum stapfianum (Kraenzl.) R.S.Oliveira & Dutilh (Amaryllidaceae) Ethanol Extract Activity on Acetylcholinesterase and PPAR-α/γ Receptors

Gomes-Copeland, K. K. P., Meireles, C. G., Gomes, J. V. D., Torres, A. G., Sinoti, S. B. P., Fonseca-Bazzo, Y. M., Magalhães, P. O., Fagg, C. W., Simeoni, L. A., & Silveira, D. (2022) · Plants · doi:10.3390/plants11223179 · Cited by 11

A spatial imaging-transcriptomics paradigm for deciphering the molecular basis of microscopic MRI in the normal brain and Alzheimer’s disease

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Ageing, proteostasis, and the gut: Insights into neurological health and disease

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Role of Oxygen Radicals in Alzheimer’s Disease: Focus on Tau Protein

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Cardiovascular Risk Factors, Alzheimer’s Disease, and the MIND Diet: A Narrative Review from Molecular Mechanisms to Clinical Outcomes

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Liver dysfunction triggers early Alzheimer’s pathology in an adult rat model of chronic liver disease

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Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms

Nelson, R. S., Dammer, E. B., Santiago, J. V., Seyfried, N. T., & Rangaraju, S. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.902146 · Cited by 10

Biomarkers of endothelial dysfunction and cognition: A two‐step IPD meta‐analysis

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Quantitative MRI of the hippocampus reveals microstructural trajectories of aging and Alzheimer’s disease pathology

Wearn, A. R., Tardif, C. L., Leppert, I. R., Baracchini, G., Hughes, C. S., Tremblay‐Mercier, J., Breitner, J. C. S., Poirier, J., Villeneuve, S., Bernhardt, B. C., et al. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2502674122 · Cited by 9

Exercise training-induced benefits for Alzheimer’s disease are associated with modulation of the BDNF-TrkB signaling complex

Taewan, K. I. M., Cho, J., & Hyunsik, K. A. N. G. (2025) · Scientific Reports · doi:10.1038/s41598-025-33262-6 · Cited by 8

Unveiling the Involvement of Herpes Simplex Virus-1 in Alzheimer’s Disease: Possible Mechanisms and Therapeutic Implications

Chauhan, P., Begum, M. Y., Narapureddy, B. R., Gupta, S., Wadhwa, K., Singh, G., Kumawat, R., Sharma, N., Ballal, S., Jha, S. K., et al. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04535-4 · Cited by 9

Methylated Ccfdna from Plasma Biomarkers of Alzheimer’s Disease Using Targeted Bisulfite Sequencing

Guemri, J., Pierre‐Jean, M., Brohard, S., Oussada, N., Horgues, C., Bonnet, É., Mauger, F., & Deleuze, J. (2022) · Epigenomics · doi:10.2217/epi-2021-0491 · Cited by 8

Differential effects of prolonged post-fixation on immunohistochemical and histochemical staining for postmortem human brains

Ma, W., Frigon, É., Maranzano, J., Zeighami, Y., & Dadar, M. (2024) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2024.1477973 · Cited by 7

Trajectory of changes in myelin basic protein levels in cerebrospinal fluid during ageing and its association with biomarkers of Alzheimer’s disease

Xu, M., Yi, X., Huang, S., Wang, Q.-H., Lai, Y., Wang, Z., Fan, D., Zeng, G., Bai, Y., Shen, Y., et al. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03369-5 · Cited by 8

Targeting glial dysfunction in Alzheimer’s disease: insights into pathogenesis and emerging therapeutics

Zhu, Q., Song, Y., Qian, Y., Zhang, R., Xue, J., & Hou, Y. (2025) · Ageing and Neurodegenerative Diseases · doi:10.20517/and.2025.25 · Cited by 6

Identification of Molecular Correlations of GSDMD with Pyroptosis in Alzheimer's Disease

Song, T., Chen, Y., Li, C., Yao, Y., Ma, S., Yazhen, S., & Cheng, J. (2024) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/0113862073285497240226061936 · Cited by 9

Defining a vitamin A5/X specific deficiency – vitamin A5/X as a critical dietary factor for mental health

Bánáti, D., Hellmann‐Regen, J., Mack, I., Young, H. A., Benton, D., Eggersdorfer, M. L., Rohn, S., Dulińska-Litewka, J., Krężel, W., & Rühl, R. (2024) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831/a000808 · Cited by 7

Exploring non-canonical targets in Alzheimer’s disease: a departure from the norm

Jain, S., & Chauhan, N. (2024) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-024-00908-7 · Cited by 7

Associations of demyelination in the right middle temporal gyrus and right praecuneus with visuospatial cognitive dysfunction in Alzheimer's disease

Ohnishi, H., Matsuoka, K., Takahashi, M., Yoshikawa, H., Minami, A., Ueda, K., Fujimoto, Y., Kiuchi, K., Ochi, T., Miyasaka, T., et al. (2024) · Psychogeriatrics · doi:10.1111/psyg.13223 · Cited by 7

Interleukin-33 has the protective effect on oligodendrocytes against impairment induced by cuprizone intoxication

Huang, H.-T., & Tzeng, S. (2023) · Neurochemistry International · doi:10.1016/j.neuint.2023.105645 · Cited by 7

Supervised latent factor modeling isolates cell-type-specific transcriptomic modules that underlie Alzheimer’s disease progression

Hodgson, L. M., Li, Y., Iturria‐Medina, Y., Stratton, J. A., Wolf, G., Krishnaswamy, S., Bennett, D. A., & Bzdok, D. (2024) · Communications Biology · doi:10.1038/s42003-024-06273-8 · Cited by 7

Long Noncoding RNAs in CNS Myelination and Disease

Zhang, J., Guan, M., Zhou, X., Berry, K., He, X., & Lu, Q. R. (2022) · The Neuroscientist · doi:10.1177/10738584221083919 · Cited by 6

Utilizing diffusion tensor imaging as an image biomarker in exploring the therapeutic efficacy of forniceal deep brain stimulation in a mice model of Alzheimer’s disease

Chen, Y., Chang, C., Liang, Y., Tseng, H.-Y., Li, S., Chang, C., Wu, Y.-T., Shao, H.-H., Chen, P., Lai, M.-L., et al. (2024) · Journal of Neural Engineering · doi:10.1088/1741-2552/ad7322 · Cited by 7

The glia‐immune network: Astrocytes and oligodendrocytes as microglial co‐ordinators in health and disease

Mitchener, V. F. T., Thackray, M. J., & Arancibia‐Cárcamo, I. L. (2025) · The Journal of Physiology · doi:10.1113/jp287015 · Cited by 8

BundleWarp: Enhancing white matter tractometry and morphometry with precise neuronal mapping using streamline-based nonlinear registration

Chandio, B. Q., Olivetti, E., Romero-Bascones, D., Thomopoulos, S. I., Villalón‐Reina, J. E., Nir, T. M., Harezlak, J., Thompson, P. M., & Garyfallidis, E. (2026) · Medical Image Analysis · doi:10.1016/j.media.2026.104114 · Cited by 7

Innate and adaptive immune mechanisms regulating central nervous system remyelination

Creswell, R., & Dombrowski, Y. (2022) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2021.12.002 · Cited by 6

Probabilistic mapping and automated segmentation of human brainstem white matter bundles

Olchanyi, M., Schreier, D. R., Li, J., Maffei, C., Sorby‐Adams, A., Kinney, H. C., Healy, B. C., Freeman, H. J., Shless, J. S., Destrieux, C., et al. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2509321123 · Cited by 7

Anisotropy of the R1/T2* value dependent on white matter fiber orientation with respect to the B0 field

Kawaguchi, S., Kan, H., Uchida, Y., Kasai, H., Hiwatashi, A., & Ueki, Y. (2024) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2024.02.010 · Cited by 5

Anthranilic Acid–G-Protein Coupled Receptor109A–Cytosolic Phospholipase A2–Myelin–Cognition Cascade: A New Target for the Treatment/Prevention of Cognitive Impairment in Schizophrenia, Dementia, and Aging

Oxenkrug, G. F. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252413269 · Cited by 7

Analysis of advanced diffusion models assessing white matter microstructure in Alzheimer’s disease

Lv, M., Zhan, K., Yang, J., Li, Y., Li, Y., Xu, X., Han, L., Feng, H., & Zhong, J. (2025) · Scientific Reports · doi:10.1038/s41598-025-09412-1 · Cited by 7

Quantitative myelin-related maps from R1 and T2* ratio images using a single ME-MP2RAGE sequence in 7T MRI

Shim, J.-M., Cho, S., Kang, S., & Kang, C. (2022) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2022.950650 · Cited by 5

The RYR3 gene is involved in Wharton’s jelly derived mesenchymal stem cell treatment of Alzheimer’s disease in rats

Ali, H., Tofrizal, T., Tjong, D. H., Yanis, A., & Yarni, S. D. (2023) · Archives of Medical Science · doi:10.5114/aoms/163353 · Cited by 5

Does Myelin Play the Leading Role in Alzheimer’s Disease Pathology?

PapuAA, E., & Rejdak, K. (2017) · Journal of Alzheimer’s Disease & Parkinsonism · doi:10.4172/2161-0460.1000321 · Cited by 2

The possible role of myelin destruction as a precipitating event in Alzheimer’s disease

Noble, M. (2003) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2003.07.001 · Cited by 35

When myelin breaks, tau aggregates — a new perspective on Alzheimer's disease

Tiane, A., van den Hove, D., & Vanmierlo, T. (2026) · Alzheimer s & Dementia · doi:10.1002/alz.71774

Disrupted myelin homeostasis in grey matter of Alzheimer’s diseasePreprint

Tiane, A., Willems, E., Koole, L., Schepers, M., van den Hove, D., & Vanmierlo, T. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.08.737146

Emerging connections between myelin and Alzheimer’s disease

Bright, A., Akay, L. A., Blanchard, J., & Tsai, L. (2025) · Nature Cell Biology · doi:10.1038/s41556-025-01701-1 · Cited by 10