Rules for functional microRNA targeting
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microRNAs (miRNAs) regulate gene expression by targeting specific mRNAs for degradation or translational repression.
“microRNAs (miRNAs) play a central role in the regulation of gene expression by targeting specific mRNAs for degradation or translational repression.”
From microRNA strand selection: Unwinding the rules (2021) · cites this paper as Kim, Chang, & Baek, 2017
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Cites
The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution
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Ribosome Profiling Shows That miR-430 Reduces Translation Before Causing mRNA Decay in Zebrafish
Bazzini, A. A., Lee, M. T., & Giraldez, A. J. (2012) · Science · doi:10.1126/science.1215704 · Cited by 709 · cited 1× · see citing works
“targeting (51), and even in the steady state, translational control may play more prominent roles for specific miRNAs (52-54).”
BackgroundAn alternative mode of microRNA target recognition
Chi, S. W., Hannon, G. J., & Darnell, R. B. (2012) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2230 · Cited by 328 · see citing works
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Kudla, G., Granneman, S., Hahn, D., Beggs, J. D., & Tollervey, D. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1017386108 · Cited by 308 · see citing works
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Cited by
Sorted by citations
microRNA strand selection: Unwinding the rules
Medley, J. C., Panzade, G., & Zinovyeva, A. Y. (2021) · WIREs RNA · doi:10.1002/wrna.1627 · Cited by 225 · see citing works
- Authors
- Kim, D., Chang, H. R., & Baek, D.
- Affiliations
- Center for RNA Research, Institute for Basic Science, Seoul National University, Seoul 08826, Korea
- Venue
- BMB Reports
- Published
- 2017-11-30
- Volume
- 50
- Issue
- 11
- Pages
- 554-559
- ISSN
- 1976-670X
- PMC
- PMC5720468
- Cited by
- 37
- References
- 4
- Language
- en
- Funders
- National Research Foundation of Korea(NRF)
- Ministry of Science, ICT and Future Planning(MSIP) (2014M3C9A3063541, 2012M3A9D1054622)
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