Chiral Drugs. An Overview

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Items 601–700 of 1,000

1. Integrating a post-column makeup pump into preparative supercritical fluid chromatography systems to address stability and recovery issues during purifications
   Lakshmikant Bajpai, Harshavardhan Naidu, Kathiravan Asokan · 2017 · Journal of Chromatography A
2. Selective enantiomer purification using magnetic oriented interacting microparticles
   Tzuriel S. Metzger, Yair Tokatly, Eytan Avigad, Shira Yochelis, Yossi Paltiel · 2020 · Separation and Purification Technology
3. Supramolecular Chiral Discrimination of D-Phenylalanine Amino Acid Based on a Perylene Bisimide Derivative
   Simona Bettini, Zois Syrgiannis, Michela Ottolini, Valentina Bonfrate, Gabriele Giancane, Ludovico Valli, Maurizio Prato · 2020 · Frontiers in Bioengineering and Biotechnology
4. Cathinones - Routine NMR methodology for enantiomer discrimination and their absolute stereochemistry assignment, using R-BINOL
   Magdalena Stolarska, Wojciech Bocian, Jerzy Sitkowski · 2020 · Journal of Molecular Structure
5. Recent Advances in Chiral Analysis for Biosamples in Clinical Research and Forensic Toxicology
   LiZhu Chen, Deqiu Zhu, Ping Xiang · 2021 · Bioanalysis
6. Emergence and stabilization of transient twisted defect structures in confined achiral liquid crystals at a phase transition
   Jose X. Velez, Zhaofei Zheng, Daniel A. Beller · 2021 · Soft Matter
7. Role of Pharmaceutical Sciences in Future Drug Discovery
   Srinivasa Reddy Bonam, Mahendran Sekar, Girijasankar Guntuku · 2021 · Future Drug Discovery
8. An easy ‘Filter-and-Separate’ method for enantioselective separation and chiral sensing of substrates using a biomimetic homochiral polymer
   Thangaraj Senthilkumar, S. K. Asha · 2015 · Chemical Communications
9. Chiral separation of α-cyclohexylmandelic acid enantiomers using ionic liquid/salt aqueous two-phase system
   Lei-Lei Chen, Fenfang Li, Zhijian Tan · 2015 · Chemical Papers
10. Design of experiment assisted concurrent enantioseparation of bupropion and hydroxybupropion by high‐performance thin‐layer chromatography
    Nejal M. Bhatt, Vijay D. Chavada, Mallika Sanyal · 2016 · Chirality
11. Enantioseparation of racemic bupivacaine via ultrasonic-assisted diastereomeric crystallization using 12,14-dinitrodehydroabietic acid
    Li Ge, Yi Zhu, Yonghui Qi · 2019 · Ultrasonics Sonochemistry
12. Stereospecific modulation of dimeric rhodopsin
    Tamar Getter, Sahil Gulati, Remy Zimmerman, Yuanyuan Chen, Frans Vinberg, Krzysztof Palczewski · 2019 · The FASEB Journal
13. 3D-Transformer: Molecular Representation with Transformer in 3D Space
    Fang Wu, Qiang Zhang, Dragomir Radev, Jiyu Cui, Wen Zhang, Huabin Xing, Ningyu Zhang, Huajun Chen · 2021 · arXiv (Cornell University)
14. Enantiomeric separation of chiral hyper-crosslinked polymer based nanotube membranes
    Rutong Zhang, Fang Wang, Meng Li · 2025 · Journal of Membrane Science
15. Light-to-matter chirality transfer in plasmonics
    Eva Yazmin Santiago, Muhammad Irfan, Óscar Ávalos‐Ovando · 2025 · Materials Horizons
16. Diastereoselective Reduction of the Enone Intermediate of Travoprost
    Chandrashekar Aswathanarayanappa, E. Bheemappa, Yadav D. Bodke · 2011 · Organic Process Research & Development
17. Mechanochemical synthesis of unsymmetrical salens for the preparation of Co–salen complexes and their evaluation as catalysts for the synthesis of α-aryloxy alcohols via asymmetric phenolic kinetic resolution of terminal epoxides
    Shengli Zuo, Shuxiang Zheng, Jianjun Liu · 2022 · Beilstein Journal of Organic Chemistry
18. Chirality As a Symmetric Basis of Self-Organization of Biomacromolecules
    V. A. Tverdislov, A. E. Sidorova, Olga E. Bagrova, Ekaterina Belova, Vladimir Sergeevich Bystrov, Natalia Timurovna Levashova, Aleksey Lutsenko, E. V. Semenova, Denis Shpigun · 2022 · BIOPHYSICS
19. Plexcitonic optical chirality in the chiral plasmonic structure-microcavity-exciton strong coupling system
    Xuyan Deng, Junqiang Li, Lei Jin, Yilin Wang, Kun Liang, Li Yu · 2023 · Optics Express
20. Chiral Light in Twisted Fabry–Pérot Cavities
    Sergey A. Dyakov, Natalia S. Salakhova, Alexey V. Ignatov · 2024 · Advanced Optical Materials
21. Impact of Model Selection and Conformational Effects on the Descriptors for In Silico Screening Campaigns: A Case Study of Rh-Catalyzed Acrylate Hydrogenation
    Margareth S. Baidun, Adarsh V. Kalikadien, Laurent Lefort, Evgeny A. Pidko · 2024 · The Journal of Physical Chemistry C
22. Liquid Chromatographic Resolution of Fendiline and Its Analogues on a Chiral Stationary Phase Based on (+)-(18-Crown-6)-2,3,11,12-tetracarboxylic Acid
    G.H. Lee, Hyun Myung · 2014 · Molecules
23. Experiment and modeling for the separation of trans-stilbene oxide enantiomers on Chiralcel OD preparative column
    Rujin Gong, Ping Li, Yu Jian-Guo · 2013 · Journal of Chromatography A
24. Molecular self-assemblies might discriminate the diffusion of chiral molecules
    Tigran Galstian, Karen Allahverdyan · 2015 · Soft Matter
25. Comparison ofR(+)-α-lipoic acid exposure afterR(+)-α-lipoic acid 200 mg and 300 mg and thioctic acid 600 mg in healthy Korean male subjects
    Jangsoo Yoon, Seol Ju Moon, Kwang-Ok Lee · 2016 · Translational and Clinical Pharmacology
26. The determination of 2-(2-hydroxypropanamido) benzoic acid enantiomers and their corresponding prodrugs in rat plasma by UHPLC–MS/MS and application to comparative pharmacokinetic study after a single oral dose
    Qili Zhang, Danlin Wang, Meiyan Zhang · 2016 · Journal of Chromatography B
27. Novel Diarylprolinol-derived Amino Perfluoroalkanesulfonamide Catalysts: Highly Enantio- and Diastereoselective Aldol Reaction
    Léopold Mpaka Lutete, Tetsuya Ikemoto · 2017 · Chemistry Letters
28. Evolution of synthetic routes towards homochiral Tapentadol
    Piotr P. Graczyk, Olga Zbrojkiewicz, Sven Nerdinger · 2017 · Tetrahedron Asymmetry
29. The Place for Enzymes and Biologically Active Peptides from Marine Organisms for Application in Industrial and Pharmaceutical Biotechnology
    Jean-Étienne R. L. Morlighem, Gandhi Rádis‐Baptista · 2018 · Current Protein and Peptide Science
30. Cobaltocene-Coupled Cumulene: A Perspective on Chiral Magnet and Spintronics Device Design
    Suranjan Shil, Sabyasachi Sen · 2020 · Inorganic Chemistry
31. Determination of Absolute Structure of Chiral Crystals Using Three-Wave X-ray Diffraction
    Ksenia A. Kozlovskaya, Elena N. Ovchinnikova, J. Kokubun · 2021 · Crystals
32. Retention indices for naturally-occurring chiral and achiral compounds on common gas chromatography chiral stationary phases
    David Alavez‐Rosas, Linh M. N. Nguyen, Ken Keefover‐Ring · 2022 · Results in Chemistry
33. 4-Isobutylmethcathinone—A Novel Synthetic Cathinone with High In Vitro Cytotoxicity and Strong Receptor Binding Preference of Enantiomers
    Martin Paškan, Silvie Rimpelová, Vladimíra Svobodová Pavlíčková, Dita Spálovská, Vladimı́r Setnička, Martin Kuchař, Michal Kohout · 2022 · Pharmaceuticals
34. Stereospecific recognition of a chiral centre over multiple flexible covalent bonds by 19 F-NMR
    Ya-Ting Chen, Bin Li, Jialiang Chen · 2022 · The Analyst
35. Cellular response to chirality and amplified chirality
    Sarita Roy, Kaushik Bhattacharya, Chitra Mandal · 2013 · Journal of Materials Chemistry B
36. Infrared, Raman and ultraviolet with circular dichroism analysis and theoretical calculations of tedizolid
    Katarzyna Michalska, Mikołaj Mizera, Kornelia Lewandowska · 2016 · Journal of Molecular Structure
37. Ion-Mobility Mass Spectrometry for Chiral Analysis of Small Molecules
    J. Diana Zhang, K. M. Mohibul Kabir, William A. Donald · 2018 · Comprehensive analytical chemistry
38. Cooperative Kinetic Model to Describe Crystallization in Solid Solution Forming Systems
    Maksymilian Olbrycht, Maciej Balawejder, Izabela Poplewska · 2019 · Crystal Growth & Design
39. Chirality of Central Nervous System (CNS) Acting Drugs: A Formidable Therapeutic Hurdle Against CNS Diseases
    Saganuwan Alhaji Saganuwan · 2019 · Central Nervous System Agents in Medicinal Chemistry
40. Determination of chiral amphetamine in seized tablets by indirect enantioseparation using GC–MS
    Abdulrhman M. Dhabbah · 2020 · Journal of King Saud University - Science
41. Speeding up Viedma Deracemization through Water‐catalyzed and Reactant Self‐catalyzed Racemization
    Carola Tortora, Christina Mai, Francesca Cascella, Michael Mauksch, Andreas Seidel‐Morgenstern, Heike Lorenz, Svetlana B. Tsogoeva · 2020 · ChemPhysChem
42. Pharmacokinetics of Chiral Drugs
    Hanqing Dong, Xiaochuan Guo, Zengbiao Li · 2011
43. Access to Enantiomeric Organic Compounds with Potential for Synthesis via Racemic Conglomerates: Inositol Derivatives as a Case in Point
    Nivedita T. Patil, Madhuri T. Patil, Nitai Sarkar, Rajesh G. Gonnade, Mysore S. Shashidhar · 2021 · Crystal Growth & Design
44. Cannabicitran: Its unexpected racemic nature and potential origins
    Jared S. Wood, William H. Gordon, Jeremy B. Morgan · 2023 · Chirality
45. Resolution and quantification of carbohydrates by enantioselective comprehensive two-dimensional gas chromatography
    Adrien D. Garcia, Vanessa Leyva, Jana Bocková · 2024 · Talanta
46. A Novel Enantioselective Chitosan-Based Stationary Phase Prepared by Molecular Imprinting of a Racemic Template
    Mokhtar Mohamed Mabrouk, Sherin Farouk Hammad, Aya A. Abdella · 2024 · Chromatographia
47. Chirality-driven strong thioredoxin reductase inhibition
    Mingkai Chen, Junping Wang, Fei Cai · 2024 · Biomaterials
48. Halogen bond-modulated solid-state reordering and symmetry breaking of azahelicenes
    Juncong Liang, Fuwei Gan, Guoli Zhang · 2025 · Nature Communications
49. Mind the gap: From resolving theoretical foundations of chiral(ity)-induced spin selectivity to pioneering implementations in quantum sensing
    Yan Xi Foo, Aisha Kermiche, Farhan T. Chowdhury, Clarice D. Aiello, Luke D. Smith · 2025 · Chemical Physics Reviews
50. Chiral Symmetry Breaking of Sodium Chlorate in a Taylor Vortex Flow
    Bowen Zhang, Gérard Coquerel, Bum Jun Park, Woo‐Sik Kim · 2024 · Crystal Growth & Design
51. Enantioselective control in chiral crystallization of ethylenediamine sulfate using optical trapping with circularly polarized laser beams.
    Teruki Sugiyama, Tung-Ming Lin, Hao-Tse Su · 2024 · Journal of Chemical Physics
52. The activity of pyrazolo[4,3- e ][1,2,4]triazine and pyrazolo[4,3- e ]tetrazolo[1,5- b ][1,2,4]triazine sulphonamide derivatives in monolayer and spheroid breast cancer cell cultures
    Anna Szymanowska, Dominika Radomska, Robert Czarnomysy, Mariusz Mojzych, Katarzyna Kotwica-Mojzych, Krzysztof Bielawski, Anna Bielawska · 2024 · Journal of Enzyme Inhibition and Medicinal Chemistry
53. Chiral Light–Matter Interactions with Thermal Magnetoplasmons in Graphene Nanodisks
    Mikkel Have Eriksen, Juan R. Deop‐Ruano, Joel D. Cox · 2024 · Nano Letters
54. Principles for Stereoselective Separation of Chiral Drug Compounds Enantiomers and Diastereomers in Pharmaceuticals and Biopharmaceuticals Using Liquid Chromatography
    Niroja Vadagam, Sharath Babu Haridasyam, Narasimha Swamy Lakka · 2025 · Chirality
55. Bioanalysis of antihistamines for clinical or forensic purposes
    Maria G. Katselou, Ioannis I. Papoutsis, Panagiota D. Nikolaou · 2016 · Biomedical Chromatography
56. Mechanical activation effect on structure, physicochemical, and biological properties of potassium/magnesium orotates
    О. М. Канунникова, В. В. Аксенова, O V Karban · 2017 · IOP Conference Series Materials Science and Engineering
57. Isomeric and Conformational Analysis of Small Drug and Drug-Like Molecules by Ion Mobility-Mass Spectrometry (IM-MS)
    Shawn T. Phillips, James N. Dodds, Jody C. May, JOHN A. JUN. MCLEAN · 2019 · Methods in molecular biology
58. Pyridino-18-crown-6 ether type chemosensors containing a benzothiazole fluorophore unit: Synthesis and enantiomeric recognition studies
    Dávid Pál, Ildikó Móczár, Balázs Szemenyei · 2019 · Tetrahedron
59. Theoretical studies of infrared signatures of proton‐bound amino acid dimers with homochiral and heterochiral moieties
    Mathias Poline, Oleksii Rebrov, Mats Larsson, Vitali Zhaunerchyk · 2020 · Chirality
60. Diastereomeric stilbenoid glucoside dimers from the rhizomes of Gnetum africanum
    Julien Gabaston, Thierry Buffeteau, Thierry Brotin · 2020 · Phytochemistry Letters
61. Strong superchiral fields and an ultrasensitive chiral sensor of biomolecules based on a dielectric photonic crystal slab with air holes
    Tong Wu, Saisai Hou, Weixuan Zhang · 2020 · Physical Review A
62. Advances on Greener Asymmetric Synthesis of Antiviral Drugs via Organocatalysis
    Arlene Gonçalves Corrêa, Everton Machado da Silva, Hérika Danielle Almeida Vidal · 2021 · Pharmaceuticals
63. On chip chiral and plasmonic hybrid dimer or tetramer: Generic way to reverse longitudinal and lateral optical binding forces
    Sudipta Biswas, Roksana Khanam Rumi, Tasnia Rahman Raima · 2021 · Chinese Physics B
64. Dimethylcysteine (DiCys)/o-Phthalaldehyde Derivatization for Chiral Metabolite Analyses: Cross-Comparison of Six Chiral Thiols
    Ankhbayar Lkhagva, Hwan‐Ching Tai · 2021 · Molecules
65. Conformational adaptability determining antibody recognition to distomer: structure analysis of enantioselective antibody against chiral drug gatifloxacin
    Lanteng Wang, Wei Xie, Wenyang Jiao · 2021 · RSC Advances
66. Pharmaceutical excipients: special focus on adverse interactions
    Suryanarayana Polaka, Shyam Sudhakar Gomte, Vikas Pandey · 2022 · Elsevier eBooks
67. Assignment-free chirality detection in unknown samples via microwave three-wave mixing
    Greta Koumarianou, Zhong Irene Wang, Lincoln Satterthwaite · 2022 · Communications Chemistry
68. Bioinspired Nitroalkylation for Selective Protein Modification and Peptide Stapling
    Sriram Mahesh, Victor Adebomi, Zilma Pereira Muneeswaran, Monika Raj · 2019 · Angewandte Chemie
69. Population Balance Modeling of Diastereomeric Salt Resolution
    Miklós H. Bosits, Álmos Orosz, Zsófia Szalay · 2023 · Crystal Growth & Design
70. Chiral separation of racemic closantel and ultratrace detection of its enantiomers in bacteria by enhanced liquid chromatography-tandem mass spectrometry combined with postcolumn infusion of ammonia
    Tongyan Ding, Longyun Liu, Yilei Liu · 2023 · Journal of Chromatography A
71. Generation of optical chirality by the tightly focused higher-order Poincaré sphere vector vortex beams
    Mengjiao Zhu, Zhongsheng Man, Liping Zhang · 2023 · Optics Communications
72. Chirality Determination of Nanocrystals by Electron Crystallography
    Lijin Wang, Yao Wang, Chaoyang Chu · 2024 · The Journal of Physical Chemistry Letters
73. Gastrointestinal Tolerability and Absorption ofR‐VersusR,S‐Lipoic Acid in Progressive Multiple Sclerosis: A Randomized Crossover Trial
    Michelle H. Cameron, Cassidy Taylor, Jodi Lapidus · 2020 · The Journal of Clinical Pharmacology
74. Stereoselective synthesis of allele-specific BET inhibitors
    Adam G. Bond, Andrea Testa, Alessio Ciulli · 2020 · Organic & Biomolecular Chemistry
75. Cu( ii )-induced twisting of the biphenyl core: exploring the effect of structure and coordination environment of biphenyl-based chiral copper( ii ) complexes on interaction with calf-thymus DNA
    Soumen Ghosh, Mehebub Ali Khan, Arghyadeep Bhattacharyya, Md. Akhtarul Alam, Ennio Zangrando, Nikhil Guchhait · 2020 · New Journal of Chemistry
76. Synthesis of α-Heteroaryl Propionic Esters by Palladium-Catalyzed α-Heteroarylation of Silyl Ketene Acetals
    Bowen Li, Bangke Luo, Caroline A. Blakemore · 2021 · Organic Letters
77. Enantioselective separation under humid conditions by chiral Hofmann clathrates: new opportunities for vintage materials
    Ekaterina Mamontova, Philippe Trens, Fabrice Salles · 2019 · Inorganic Chemistry Frontiers
78. Pharmacology of Chiral Drugs
    Yongge Liu, Xiaohui Gu · 2011
79. Functional analysis of recombinant menthone menthol reductase by chiral GC and GC-MS
    Faezeh Jame-Chenarboo, Atousa Aliahmadi, Saba Khavari · 2022 · Industrial Crops and Products
80. Molecular Chiral Response Enhanced by Crosstalking Quasi-Bound States in the Continuum
    Diana Shakirova, Adrià Canós Valero, Daniil Riabov, Hatice Altug, Andrey Bogdanov, Thomas Weiss · 2025 · ACS Photonics
81. Heterogeneous Photocatalysis for Late‐Stage Functionalization: A Sustainable Frontier for Complex Molecule Synthesis
    Prakash Kumar Sahoo, Shoubhik Das · 2026 · ChemSusChem
82. Structure, binding energy and chiral discrimination in oxathiirane homodimers
    Goar Sánchez‐Sanz, Cristina Trujillo, Ibón Alkorta · 2016 · Computational and Theoretical Chemistry
83. Moiré Metasurface with Triple-Band Near-Perfect Chirality
    Bokun Lyu, Haojie Li, Qianwen Jia · 2023 · Chinese Physics Letters
84. ChiENN: Embracing Molecular Chirality with Graph Neural Networks
    Piotr Gaiński, Michał Koziarski, Jacek Tabor · 2023 · Lecture notes in computer science
85. Development of a Practical and Scalable Process for Lifitegrast
    Mahender Madaraboina, Bhimavarapu Srinivasa Reddy, Venkata Siva Kumar Boddupalli, Pavani Sankar Reddy, Jaya Shree Anireddy, Rajeev Rehani Budhdev, Rakeshwar Bandichhor, Srinivas Achanta · 2023 · Organic Process Research & Development
86. Simultaneously resolving BINOL and proline using a stoichiometric cocrystal switch
    Sarita Songsermsawad, Oleksii Shemchuk, Koen Robeyns · 2024 · Chemical Communications
87. Elucidating Chiral Resolution of Aromatic Amino Acids Using Glycopeptide Selectors: A Combined Molecular Docking and Chromatographic Study
    Dehbiya Gherdaoui, Madiha Melha Yahoum, Selma Toumi et al. · 2024 · International Journal of Molecular Sciences
88. Amorphous Solid Dispersion Formation for Enhanced Release Performance of Racemic and Enantiopure Praziquantel
    Hector Polyzois, Hanh Thuy Nguyen, Benedito Roberto de Alvarenga · 2024 · Molecular Pharmaceutics
89. Enhanced Circular Dichroism via Symmetry Breaking in a Chiral Plasmonic Nanoparticle Oligomer
    Khai Quang Le · 2018 · Journal of Electronic Materials
90. Synthesis and biological evaluation of 12-, 13-, 14-membered macrolides and open chain 2,6-trans-disubstituted dihydropyran analogues for aspergillides
    Srihari Pabbaraja, Naresh Gantasala, Y. Sridhar, Hari Krishna Namballa, Subhashini Gundeboina, Mallikharjuna Rao Lambu, Sanjeev Meena, Dipak B. Datta · 2018 · Tetrahedron Letters
91. Novel enantioselective synthesis of (S)-ketamine using chiral auxiliary and precursor Mannich base
    Seyed Gohari, Abdollah Javidan, Ali Moghimi · 2019 · Canadian Journal of Chemistry
92. Sonochemically modified ovalbumin enhances enantioenrichment of some amino acids
    Amruta Mutalikdesai, Molhm Nassir, Abed Saady · 2019 · Ultrasonics Sonochemistry
93. Identification of Two Hetero-Substituent-Aromatic Isomers of - 4- and 7-Hydroxy Coumarin with the Belousov-Zhabotinsky Oscillator
    Muhammad Yasir Nawabi, Waqar Uddin, Guang Hu · 2019 · International Journal of Electrochemical Science
94. Kinetic model of resolution of 4-methoxymandelic acid enantiomers by lipase-catalyzed transesterification reaction
    Xin Mei Yuan, Panliang Zhang, Weifeng Xu · 2019 · Applied Catalysis A General
95. High-pressure melting equilibrium of chiral compounds: A practical study on chlorinated mandelic acids under carbon dioxide atmosphere
    Márton Kőrösi, János Béri, Alina Hanu, Sabine Kareth, Edit Székely · 2019 · Journal of CO2 Utilization
96. Development of a millimeter-period rf undulator
    Filippos Toufexis, Sami G. Tantawi · 2019 · Physical Review Accelerators and Beams
97. “Atropisomeric” Drugs: Basic Concept and Example of Application to Drug Development
    Robert B. Raffa, Joseph V. Pergolizzi, Robert J. Taylor · 2020 · Pharmacology &amp Pharmacy
98. Chiral separation of beta-blockers by high-performance liquid chromatography and determination of bisoprolol enantiomers in surface waters
    Marijana Pocrnić, Martin Ansorge, Magda Dovhunová · 2020 · Archives of Industrial Hygiene and Toxicology
99. One-pot method for the synthesis of 1-aryl-2-aminoalkanol derivatives from the corresponding amides or nitriles
    Jan Otevřel, David Svestka, Pavel Bobáľ · 2020 · RSC Advances
100. Chiral discrimination in a mutated IDH enzymatic reaction in cancer: a computational perspective
     Masthan Thamim, Krishnan Thirumoorthy · 2020 · European Biophysics Journal