Chiral Drugs. An Overview

Role of Pharmacokinetics and Metabolism in Drug Discovery and Development

Lin, J. H., & Lu, A. Y. H. (1997) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01340-1 · Cited by 713

The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias

Barrett, A. M., & Cullum, V. A. (1968) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1968.tb07949.x · Cited by 583

Enantioselective Aspects of Drug Action and Disposition: Therapeutic Pitfalls

Jamali, F., Mehvar, R., & Pasutto, F. M. (1989) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600780902 · Cited by 395

Pharmacodynamic and pharmacokinetic differences between drug enantiomers in humans: An overview

Drayer, D. (1986) · Clinical pharmacology and therapy · doi:10.1038/clpt.1986.150 · Cited by 299

Stereochemistry in Drug Action

McConathy, J., & Owens, M. J. (2003) · The Primary Care Companion For CNS Disorders · doi:10.4088/pcc.v05n0202 · Cited by 297

The importance of stereoselective determination of drugs in the clinical laboratory

Rentsch, K. (2002) · Journal of Biochemical and Biophysical Methods · doi:10.1016/s0165-022x(02)00124-0 · Cited by 233

Bioanalysis of drugs by liquid-phase microextraction coupled to separation techniques

Pedersen‐Bjergaard, S., & Rasmussen, K. E. (2004) · Journal of Chromatography B · doi:10.1016/j.jchromb.2004.08.034 · Cited by 215

Mechanism of action of barbiturates.

Ho, I., & Harris, R. (1981) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.21.040181.000503 · Cited by 197

The specification of asymmetric configuration in organic chemistry

Cahn, R., Ingold, C., & Prelog, V. (1956) · Experientia · doi:10.1007/bf02157171 · Cited by 190

Chiral Separations By Liquid Chromatography And Related Technologies

Aboul-Enein, H., & Ali, I. (2003) · doi:10.1201/9780203911112 · Cited by 140

A biomimetic metal–organic framework with cuboid inner cavities for enantioselective separation

Zhu, C., Zhang, A., Li, Y., et al. (2022) · Inorganic Chemistry Frontiers · doi:10.1039/d2qi00152g · Cited by 14

An Examination of the Phase Transition Thermodynamics of ( S )- and ( RS )-Naproxen as a Basis for the Design of Enantioselective Crystallization Processes

Buchholz, H. K., Emel′yanenko, V. N., Lorenz, H., et al. (2016) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2016.02.032 · Cited by 14

Combined docking and molecular dynamics study of lipase catalyzed kinetic resolution of 1-phenylethanol in organic solvents

Mathpati, A. C., & Bhanage, B. M. (2016) · Journal of Molecular Catalysis B Enzymatic · doi:10.1016/j.molcatb.2016.12.005 · Cited by 14

Syntheses, Characterization, Resolution, and Biological Studies of Coordination Compounds of Aspartic Acid and Glycine

Aiyelabola, T. O., Akinkunmi, E. O., Ojo, I. A. O., et al. (2017) · Bioinorganic Chemistry and Applications · doi:10.1155/2017/2956145 · Cited by 14

Sodium deoxycholate/TRIS-based hydrogels for multipurpose solute delivery vehicles: Ambient release, drug release, and enantiopreferential release

McNeel, K. E., Siraj, N., Negulescu, I. I., et al. (2017) · Talanta · doi:10.1016/j.talanta.2017.09.025 · Cited by 14

Catalytic Asymmetric Synthesis of Cyclopentene-spirooxindoles Bearing Vinylsilanes Capable of Further Transformations

Cobo, A. A., Armstrong, B. M., Fettinger, J. C., et al. (2019) · Organic Letters · doi:10.1021/acs.orglett.9b02852 · Cited by 14

Molecular dynamics simulation study of the effect of single-walled carbon nanotube on the enantioseparation ability of a chiral ionic liquid

Sedghamiz, T., & Bahrami, M. (2020) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2020.112769 · Cited by 14

Natural deep eutectic solvents are viable solvents for plant cell culture-assisted stereoselective biocatalysis

Pavoković, D., Košpić, K., Panić, M., Redovniković, I. R., & Bubalo, M. C. (2020) · Process Biochemistry · doi:10.1016/j.procbio.2020.03.020 · Cited by 14

Alkaloids isolated from Tropaeolum tuberosum with cytotoxic activity and apoptotic capacity in tumour cell lines

Ticona, L. A., Sebastián, J. A., Șerban, A. M., et al. (2020) · Phytochemistry · doi:10.1016/j.phytochem.2020.112435 · Cited by 14

Kinetic Resolution of Racemic Mixtures via Enantioselective Photocatalysis

Arbell, N., Bauer, K., & Paz, Y. (2021) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.1c12216 · Cited by 14

Learning 3D Representations of Molecular Chirality with Invariance to Bond RotationsPreprint

Adams, K., Pattanaik, L., & Coley, C. W. (2021) · arXiv (Cornell University) · doi:10.48550/arxiv.2110.04383 · Cited by 43

Hydrogen Bonding Interaction Enabled Asymmetric C─H Acylation of Trifluoroethanol by Dual Nickel/Photoredox Catalysis

Li, Y., Hu, D., Ren, W., et al. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202424324 · Cited by 13

Emerging optical techniques for sorting and detection of chiral particles

Shi, Y., Li, C., Lin, X., Xue, W., Lai, C., He, T., Song, Q., Wang, Z., Wang, Y., Tsai, D. P., et al. (2026) · Opto-Electronic Advances · doi:10.29026/oea.2026.250255 · Cited by 17

A Systematic Review on Distribution and Ecological Risk Assessment for Chiral Pharmaceuticals in Environmental Compartments

Mejías, C., Arenas, M., Martı́n, J., et al. (2022) · Reviews of Environmental Contamination and Toxicology · doi:10.1007/s44169-021-00003-5 · Cited by 13

The association of chiral characteristic with drug withdrawal due to safety: A comparative analysis

Aydın, V., Bahar, A., Vızdıklar, C., & Akıcı, A. (2022) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.15486 · Cited by 14

Unusual enantioselective cytoplasm-to-nucleus translocation and photosensitization of the chiral Ru(II) cationic complex via simple ion-pairing with lipophilic weak acid counter-anions

Chao, X., Huang, C., Tang, M., et al. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad155 · Cited by 13

Direct Enantiomer Differentiation of Drugs and Drug-Like Compounds via Noncovalent Copper–Amino Acid Complexation and Ion Mobility-Mass Spectrometry

Blakley, B. K., Zlibut, E., Gupta, R., et al. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.4c02710 · Cited by 13

Direct Chiral Discrimination with NMR

Wadhwa, S., Buyens, D. M. S., & Korvink, J. G. (2024) · Advanced Materials · doi:10.1002/adma.202408547 · Cited by 14

Portable, Battery Operated Capillary Electrophoresis with Optical Isomer Resolution Integrated with Ionization Source for Mass Spectrometry

Moini, M., & Rollman, C. M. (2015) · Journal of the American Society for Mass Spectrometry · doi:10.1007/s13361-015-1314-8 · Cited by 13

Analysis and magnetic modulation of chiro-optical properties in anisotropic chiral and magneto-chiral plasmonic systems

Feng, H. Y., de Dios, C., Garcı́a, F., et al. (2017) · Optics Express · doi:10.1364/oe.25.031045 · Cited by 13

Kinetic and mechanistic insight into the formation of amphetamine using the Leuckart–Wallach reaction and interaction of the drug with GpC·CpG base-pair step of DNA: a DFT study

Ostovari, H., Zahedi, E., Sarvi, I., & Shiroudi, A. (2018) · Monatshefte für Chemie - Chemical Monthly · doi:10.1007/s00706-018-2145-7 · Cited by 13

Sulfide‐Catalyzed Trifluoromethylthiolation‐Cyclization of Tryptamine Derivatives

Guo, R. X., Cai, B., Jin, M. Y., et al. (2019) · Asian Journal of Organic Chemistry · doi:10.1002/ajoc.201900068 · Cited by 13

Development of an effective novel validated stability‐indicating HPLC method for the resolution of brivaracetam stereoisomeric impurities

Baksam, V. K., Nimmakayala, S., Pocha, V. R., et al. (2020) · Chirality · doi:10.1002/chir.23269 · Cited by 13

Orientation averaging of optical chirality near nanoparticles and aggregates

Fazel-Najafabadi, A., Schuster, S., & Auguié, B. (2021) · Physical review. B./Physical review. B · doi:10.1103/physrevb.103.115405 · Cited by 13

Molecular dynamics simulations of chiral recognition of drugs by amylose polymers coated on amorphous silica

Wang, X., Jameson, C. J., & Murad, S. (2021) · Molecular Physics · doi:10.1080/00268976.2021.1922772 · Cited by 13

Photoelectron circular dichroism of a model chiral anion

Artemyev, A. N., Kutscher, E., & Demekhin, P. V. (2022) · The Journal of Chemical Physics · doi:10.1063/5.0079723 · Cited by 13

Stereoselectivity of Interaction of Nonsteroidal Anti-Inflammatory Drug S-Ketoprofen with L/D-Tryptophan in Phospholipid Membranes

Mastova, A. V., Selyutina, O. Y., & Polyakov, N. E. (2022) · Membranes · doi:10.3390/membranes12050460 · Cited by 14

Collective lattice and plasmonic resonances in the enhancement of circular dichroism in disk–rod metasurface

Romashkina, A., Novikov, V. B., & Murzina, T. V. (2023) · Journal of Applied Physics · doi:10.1063/5.0124798 · Cited by 13

Liquid chromatographic resolution of racemic rasagiline and its analogues on a chiral stationary phase based on (+)‐(18‐crown‐6)‐2,3,11,12‐tetracarboxylic acid

Tak, K. M., Park, E. J., & Hyun, M. H. (2013) · Journal of Separation Science · doi:10.1002/jssc.201300819 · Cited by 13

A thalidomide templated molecularly imprinted polymer that promotes a biologically active chiral entity tagged in colon carcinoma cells and protein-related immune activation

Jaiswal, L., Rakkit, S., Pochin, K., et al. (2015) · Process Biochemistry · doi:10.1016/j.procbio.2015.09.016 · Cited by 13

Functional Characterization of a Marine Bacillus Esterase and its Utilization in the Stereo-Selective Production of D-Methyl Lactate

Huang, J., Zhang, Y., & Hu, Y. (2016) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-016-2180-y · Cited by 13

Chirality and neuropsychiatric drugs: an update on stereoselective disposition and clinical pharmacokinetics of bupropion

Dash, R. P., Rais, R., & Srinivas, N. R. (2017) · Xenobiotica · doi:10.1080/00498254.2017.1376765 · Cited by 13

Simultaneous determination of guaifenesin enantiomers and ambroxol HCl using 50‐mm chiral column for a negligible environmental impact

Tantawy, M. A., Yehia, A. M., & Aboul-Enein, H. Y. (2019) · Chirality · doi:10.1002/chir.23116 · Cited by 13

NPC1161B, an 8-Aminoquinoline Analog, Is Metabolized in the Mosquito and Inhibits Plasmodium falciparum Oocyst Maturation

Hamerly, T., Tweedell, R. E., Hritzo, B. A., et al. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01265 · Cited by 13

Efficient Resolution of Racemic Guaifenesin via Batch-Preferential Crystallization Processes

Cascella, F., Temmel, E., Seidel‐Morgenstern, A., et al. (2019) · Organic Process Research & Development · doi:10.1021/acs.oprd.9b00413 · Cited by 13

Chirality and stereoisomerism of organic multicomponent crystals in the CSD

Grothe, E., Meekes, H., & Gelder, R. D. (2020) · CrystEngComm · doi:10.1039/d0ce00403k · Cited by 13

Chiral liquid chromatography-tandem mass spectrometry analysis of superwarfarin rodenticide stereoisomers – Bromadiolone, difenacoum and brodifacoum – In human plasma

Nosal, D. G., Feinstein, D. L., & van Breemen, R. B. (2021) · Journal of Chromatography B · doi:10.1016/j.jchromb.2021.122529 · Cited by 13

Molecular basis for stereoselective transport of fenoterol by the organic cation transporters 1 and 2

Gebauer, L., Murugan, N. A., Jensen, O., et al. (2021) · Biochemical Pharmacology · doi:10.1016/j.bcp.2021.114871 · Cited by 13

Discovery of new chiral sulfonamides bearing benzoxadiazole as HIF inhibitors for non-small cell lung cancer therapy: design, microwave-assisted synthesis, binding affinity, in vitro antitumoral activities and in silico studies

Kahraman, D. T., Karaküçük‐İyidoğan, A., Saygıdeğer, Y., Oruç‐Emre, E. E., Taşkın‐Tok, T., Başaran, E., İlhan, S., Demir, B. S., Üren, A., & Bayram, H. (2021) · New Journal of Chemistry · doi:10.1039/d1nj03809e · Cited by 12

Enantioselectivity of Pentedrone and Methylone on Metabolic Profiling in 2D and 3D Human Hepatocyte-like Cells

Silva, B., Rodrigues, J. S., Almeida, A. S., Lima, A. R., Fernandes, C., de Pinho, P. G., Miranda, J. P., & Remião, F. (2022) · Pharmaceuticals · doi:10.3390/ph15030368 · Cited by 12

Enantioseparation of basic drugs by reverse phase high‐performance liquid chromatography system using carboxymethyl‐β‐cyclodextrin as chiral mobile phase additive

Ao, Q., Zhao, H., Tong, T., et al. (2022) · Chirality · doi:10.1002/chir.23470 · Cited by 12

R- Is Superior to S-Form of α-Lipoic Acid in Anti-Inflammatory and Antioxidant Effects in Laying Hens

Liu, Q., Li, W., Huang, S., Zhao, L., Zhang, J., Ji, C., & Ma, Q. (2022) · Antioxidants · doi:10.3390/antiox11081530 · Cited by 13

Multi-enzyme catalysed processes using purified and whole-cell biocatalysts towards a 1,3,4-substituted tetrahydroisoquinoline

Weber, D. L., Bastos, L. D. S., Winkler, M., et al. (2023) · RSC Advances · doi:10.1039/d3ra01210g · Cited by 12

Chiral separation and molecular modeling study of decursinol and its derivatives using polysaccharide-based chiral stationary phases

Nguyen, B. T., Choi, Y. J., Kim, K. H., et al. (2023) · Journal of Chromatography A · doi:10.1016/j.chroma.2023.464165 · Cited by 12

Plasmon-enhanced circular dichroism spectroscopy of chiral drug solutions

Venturi, M., Adhikary, R., Sahoo, A., et al. (2023) · The Journal of Chemical Physics · doi:10.1063/5.0169826 · Cited by 12

On Solute Recovery and Productivity in Chiral Resolution through Solid-State Deracemization by Temperature Cycling

Hosseinalipour, M. S., Deck, L.-T., & Mazzotti, M. (2024) · Crystal Growth & Design · doi:10.1021/acs.cgd.4c00233 · Cited by 14

Synthesis of chiral graphene structures and their comprehensive applications: a critical review

Sinha, A., & So, H. (2024) · Nanoscale Horizons · doi:10.1039/d4nh00021h · Cited by 12

In Depth Analysis of Chiroptical Properties of Enones Derived from Abietic Acid

Masnyk, M., Butkiewicz, A., Górecki, M., et al. (2018) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.7b02911 · Cited by 12

Improved chromatographic diastereoresolution of cyclopropyl dafachronic acid derivatives using chiral anion exchangers

Ianni, F., Pucciarini, L., Carotti, A., et al. (2018) · Journal of Chromatography A · doi:10.1016/j.chroma.2018.04.062 · Cited by 12

Enantioseparation using carboxymethyl-6-(4-methoxybenzylamino)-β-cyclodextrin as a chiral selector by capillary electrophoresis and molecular modeling study of the recognition mechanism

Zhao, Y. Q., Wang, J., Liu, Y., et al. (2019) · New Journal of Chemistry · doi:10.1039/c9nj04771a · Cited by 12

BESTox: A Convolutional Neural Network Regression Model Based on Binary-Encoded SMILES for Acute Oral Toxicity Prediction of Chemical Compounds

Chen, J., Cheong, H.-H., & Siu, S. W. I. (2020) · Lecture notes in computer science · doi:10.1007/978-3-030-42266-0_12 · Cited by 13

A novel pyrazolo [3,4-d] pyrimidine, KKC080106, activates the Nrf2 pathway and protects nigral dopaminergic neurons

Lee, J. A., Kim, H. R., Son, H. J., Shin, N., Han, S. H., Cheong, C. S., Kim, D. J., & Hwang, O. (2020) · Experimental Neurology · doi:10.1016/j.expneurol.2020.113387 · Cited by 12

First principle calculation of nonlinear optical response of (D/L)-Alanine in chiral carbon nanotube

Zhang, F., Xu, H., & Su, Z. (2021) · Carbon · doi:10.1016/j.carbon.2021.07.047 · Cited by 12

Enantioselective Lactonization by π‐Acid‐Catalyzed Allylic Substitution: A Complement to π‐Allylmetal Chemistry

Mangadan, A. R. K., Liu, J., & Aponick, A. (2021) · Angewandte Chemie International Edition · doi:10.1002/anie.202108336 · Cited by 12

An Optical Cluster: Near‐Field Optical Sorting and Separation of Plasmonic, Dielectric, and Chiral Nanoparticle

Das, S. C., Mahdy, M. R. C., Islam, M. S., et al. (2021) · Annalen der Physik · doi:10.1002/andp.202100299 · Cited by 12

An efficient process for recycle S-valsartan from the racemic coproduct via diastereomeric crystallization by using natural dehydroabietylamine as the enantioselective recognition media

Zhu, Y., Ge, L., Chen, L., et al. (2021) · Separation and Purification Technology · doi:10.1016/j.seppur.2021.120056 · Cited by 12

Huiles essentielles et chiralité moléculaire

Aribi‐Zouioueche, L., & Couic-Marinier, F. (2021) · Comptes Rendus Chimie · doi:10.5802/crchim.130 · Cited by 12

Enantioselective chiral sorption of 1-phenylethanol by homochiral 1D coordination polymers

Cao, W., Missen, O. P., & Turner, D. R. (2021) · Inorganic Chemistry Frontiers · doi:10.1039/d1qi01457a · Cited by 12

Potential Stereoselective Binding of Trans-(±)-Kusunokinin and Cis-(±)-Kusunokinin Isomers to CSF1R

Ayudhya, C. C. N., Graidist, P., & Tipmanee, V. (2022) · Molecules · doi:10.3390/molecules27134194 · Cited by 13

Development and validation of a UFLC-MS/MS method for determination of 7′(Z)-(8″S, 8‴S)-epi-salvianolic acid E, (7′R, 8′R, 8″S, 8‴S)-epi-salvianolic acid B and salvianolic acid B in rat plasma and its application to pharmacokinetic studies

Xie, X., Sun, W., Miao, J., Huang, J., Xu, J., Liu, X., Sun, H., Tong, L., & Sun, G. (2016) · Journal of Chromatography B · doi:10.1016/j.jchromb.2016.03.042 · Cited by 12

Characterisation of 6-DMATS Mo from Micromonospora olivasterospora leading to identification of the divergence in enantioselectivity, regioselectivity and multiple prenylation of tryptophan prenyltransferases

Winkelblech, J., Xie, X., & Li, S. (2016) · Organic & Biomolecular Chemistry · doi:10.1039/c6ob01803c · Cited by 12

Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A

Horton, J. R., Liu, X., Wu, L., Zhang, K., Shanks, J. R., Zhang, X., Rai, G., Mott, B. T., Jansen, D. J., Kales, S. C., et al. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.8b00261 · Cited by 13

On the Enantioselective HPLC Separation Ability of Sub-2 µm Columns: Chiralpak® IG-U and ID-U

Ibrahim, D., & Ghanem, A. (2019) · Molecules · doi:10.3390/molecules24071287 · Cited by 12

Delving noble metal and semiconductor nanomaterials into enantioselective analysis

Wen, Y., Li, Z., & Jiang, J. (2019) · Chinese Chemical Letters · doi:10.1016/j.cclet.2019.05.036 · Cited by 12

Chiral Differentiation of Non-Covalent Diastereomers Based on Multichannel Dissociation Induced by 213-nm Ultraviolet Photodissociation

Shi, Y., Zhou, M., Zhang, K., Ma, L., & Kong, X. (2019) · Journal of the American Society for Mass Spectrometry · doi:10.1007/s13361-019-02302-7 · Cited by 12

Selective Homodecoupled 1D-1H NMR Experiment for Unravelling Enantiomers

Naresh, K. S., Kumar, T. N., Singam, S. S. R., et al. (2022) · Analytical Chemistry · doi:10.1021/acs.analchem.2c01020 · Cited by 12

Toroidal dipole Fabry–Perot bound states in the continuum metasurfaces for ultrasensitive chiral detection

Li, C., He, T., Rao, X., Feng, C., Zhu, J., Dong, S., Wei, Z., Jiao, H., Shi, Y., Wang, Z., et al. (2025) · Photonics Research · doi:10.1364/prj.559587 · Cited by 11

Synthesis and Investigation of Chiral Poly(2,4-disubstituted-2-oxazoline)-Based Triblock Copolymers, Their Self-Assembly, and Formulation with Chiral and Achiral Drugs

Yang, M., Haider, M. S., Forster, S., Hu, C., & Luxenhofer, R. (2022) · Macromolecules · doi:10.1021/acs.macromol.2c00229 · Cited by 12

Design and development of efficient synthetic strategies for the chiral synthesis of novel ketolide antibiotic, nafithromycin (WCK 4873)

Bhavsar, S., Tadiparthi, R., Gupta, S. V., et al. (2023) · Chemical Papers · doi:10.1007/s11696-023-02725-3 · Cited by 11

Online preconcentration and chiral separation of ofloxacin in exhaled breath condensate by capillary electrophoresis

Javan, M., Seyfinejad, B., Rahimpour, E., et al. (2023) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2023.115641 · Cited by 11

Negative Nonlinear CD–ee Dependence in Polycrystalline BINOL Thin Films

Liang, K., Ristow, F., Li, K., et al. (2023) · Journal of the American Chemical Society · doi:10.1021/jacs.3c12253 · Cited by 11

Ni/Cu Dual‐Catalyzed Propargylation for the Stereodivergent Synthesis of Methohexital

Chang, X., Zhang, J., Cheng, X., et al. (2024) · Advanced Science · doi:10.1002/advs.202406764 · Cited by 11

From barbiturates to ganaxolone: The importance of chirality in drug development and in understanding the actions of old and new antiseizure medications

Bialer, M., & Perucca, E. (2025) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2025.108808 · Cited by 13

Enantioselective determination of econazole in rat plasma and its application to a pharmacokinetic study

Zhang, J., Liu, B., Jiang, Z., et al. (2020) · Analytical Biochemistry · doi:10.1016/j.ab.2020.113791 · Cited by 11

A multi-residue chiral liquid chromatography coupled with tandem mass spectrometry method for analysis of antifungal agents and their metabolites in aqueous environmental matrices

Wattanayon, R., & Kasprzyk‐Hordern, B. (2021) · Analytical Methods · doi:10.1039/d1ay00556a · Cited by 13

Selective transport of chiral particles by optical pulling forces

Zheng, H., Li, X., Chen, H., et al. (2021) · Optics Express · doi:10.1364/oe.444627 · Cited by 11

Structural Elucidation of the Mechanism of Molecular Recognition in Chiral Crystalline Sponges

Zhang, S., Fairen‐Jiménez, D., & Zaworotko, M. J. (2020) · Angewandte Chemie · doi:10.1002/ange.202006438 · Cited by 11

Ferrorotational Selectivity in Ilmenites

Fang, X., De, C., Huang, F., Xu, X., Du, K., Wang, K., Li, B., & Cheong, S. (2023) · Journal of the American Chemical Society · doi:10.1021/jacs.3c08635 · Cited by 11

Fast and Sensitive Chiral Analysis of Amphetamines and Cathinones in Equine Urine and Plasma Using Liquid Chromatography Tandem Mass Spectrometry

Wang, C. C., Hartmann‐Fischbach, P., Krueger, T. R., et al. (2015) · American Journal of Analytical Chemistry · doi:10.4236/ajac.2015.613094 · Cited by 11

A New and Enantioselective Chromatographic Method for Linagliptin on Amylose Coated Chiral Stationary Phase

Kumar, C. V., Aparna, P., Vasa, P. K., et al. (2016) · American Journal of Analytical Chemistry · doi:10.4236/ajac.2016.77051 · Cited by 11

A Quantum-Chemical DFT Approach to Elucidation of the Chirality Transfer Mechanism of the Enantioselective Suzuki–Miyaura Cross-Coupling Reaction

Jasiński, R., Demchuk, O. M., & Babyuk, D. (2017) · Journal of Chemistry · doi:10.1155/2017/3617527 · Cited by 11

Separation and quantitation of eight isomers in a molecule with three stereogenic centers by normal phase liquid chromatography

Joshi, N., Dhamarlapati, B., Pillai, A., Paulose, J., Tan, J., Blue, L. E., Tedrow, J. S., & Farrell, B. (2018) · Journal of Chromatography A · doi:10.1016/j.chroma.2018.01.035 · Cited by 11

Co-assembly of exfoliated Mg/Al layered double hydroxides nanosheets with sulfobutyl ether-β-cyclodextrin for enantioseparation of racemic propranolol

Zhu, F., Wang, L., Liao, S., et al. (2018) · Applied Clay Science · doi:10.1016/j.clay.2018.05.031 · Cited by 11

DoE Approach: A validated Stability Indicating RP-HPLC Method Development for the Separation of Diasteromeric Analogs and Process Impurities of Carfilzomib

Gopireddy, R. R., Maruthapillai, A., Devikala, S., et al. (2019) · Materials Today Proceedings · doi:10.1016/j.matpr.2019.04.174 · Cited by 11

Application of chiral chromatography in radiopharmaceutical fields: A review

Moein, M. M., & Tran, T. A. (2020) · Journal of Chromatography A · doi:10.1016/j.chroma.2020.461611 · Cited by 11

Peptoids as a Chiral Stationary Phase for Liquid Chromatography: Insights from Molecular Dynamics Simulations

Hoyas, S., Roscioni, O. M., Tonneaux, C., et al. (2021) · Biomacromolecules · doi:10.1021/acs.biomac.1c00302 · Cited by 11

X-ray structures and spectroscopic properties of chiral thiosemicarbazides as studied by computational calculations

Kanmazalp, S. D., Başaran, E., Karaküçük‐İyidoğan, A., et al. (2017) · Phosphorus, sulfur, and silicon and the related elements · doi:10.1080/10426507.2017.1289380 · Cited by 11

Enantioselective electrophilic fluorination of α-aryl-tetralones using a preparation of N-fluoroammonium salts of cinchonine

de Souza, L. G., Domingos, J. L. O., Fernandes, T. D. A., et al. (2018) · Journal of Fluorine Chemistry · doi:10.1016/j.jfluchem.2018.11.007 · Cited by 11

Message Passing Networks for Molecules with Tetrahedral ChiralityPreprint

Pattanaik, L., Ganea, O.-E., Coley, I., Jensen, K. F., Green, W. H., & Coley, C. W. (2020) · arXiv (Cornell University) · doi:10.48550/arxiv.2012.00094 · Cited by 33

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Gerard, C. J. J., Pinètre, C., Cercel, H., et al. (2024) · Crystal Growth & Design · doi:10.1021/acs.cgd.4c00114 · Cited by 10

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Yi, W., Huang, H., Lai, C., et al. (2024) · Micromachines · doi:10.3390/mi15101267 · Cited by 10

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Raza, F., Chen, R., & Ma, Y. (2024) · Journal of Applied Physics · doi:10.1063/5.0242714 · Cited by 10

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Yu, J., Sui, Y.-F., Chen, Z., et al. (1996) · Europe PMC (PubMed Central) · Cited by 3

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Qian, M. X., Finco, T. S., Swagler, A. R., et al. (1991) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.35.6.1247 · Cited by 20

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