Role of TERRA in the regulation of telomere length

Shelterin: the protein complex that shapes and safeguards human telomeres

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Mammalian Telomeres End in a Large Duplex Loop

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How Shelterin Protects Mammalian Telomeres

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Origin of Concatemeric T7DNA

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Telomeric Repeat–Containing RNA and RNA Surveillance Factors at Mammalian Chromosome Ends

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Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

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Alternative lengthening of telomeres: models, mechanisms and implications

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Telomeres: protecting chromosomes against genome instability

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How Telomeres Solve the End-Protection Problem

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Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II

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Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body.

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The epigenetic regulation of mammalian telomeres

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Purification of Proteins Associated with Specific Genomic Loci

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TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres

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Telomere Length Homeostasis Is Achieved via a Switch between Telomerase- Extendible and -Nonextendible States

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Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells

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Homologous Recombination Generates T-Loop-Sized Deletions at Human Telomeres

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Replication and protection of telomeres

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Telomerase and DNA End Replication: No Longer a Lagging Strand Problem?

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The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase

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Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres

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TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA

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The Rat1p 5′ to 3′ Exonuclease Degrades Telomeric Repeat-Containing RNA and Promotes Telomere Elongation in Saccharomyces cerevisiae

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Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence

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Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase

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Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α

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A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex

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Telomeric Noncoding RNA TERRA Is Induced by Telomere Shortening to Nucleate Telomerase Molecules at Short Telomeres

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Molecular Dissection of Telomeric Repeat-Containing RNA Biogenesis Unveils the Presence of Distinct and Multiple Regulatory Pathways

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Cell cycle-dependent modulation of telomerase activity in tumor cells.

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Hypomethylation of subtelomeric regions in ICF syndrome is associated with abnormally short telomeres and enhanced transcription from telomeric regions

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The role of senescence and immortalization in carcinogenesis

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Telomeric repeat-containing RNA structure in living cells

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Regulation of Telomere Length by G-Quadruplex Telomere DNA- and TERRA-Binding Protein TLS/FUS

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An Intramolecular G-Quadruplex Structure Is Required for Binding of Telomeric Repeat-Containing RNA to the Telomeric Protein TRF2

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A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection

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Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome

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hnRNP A1 associates with telomere ends and stimulates telomerase activity

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Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription

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TERRA biogenesis, turnover and implications for function

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The THO complex component Thp2 counteracts telomeric R‐loops and telomere shortening

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TERRA transcripts are bound by a complex array of RNA-binding proteins

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Structural Basis of Telomeric RNA Quadruplex−Acridine Ligand Recognition

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TERRA Promotes Telomere Shortening through Exonuclease 1–Mediated Resection of Chromosome Ends

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MLL Associates with Telomeres and Regulates Telomeric Repeat-Containing RNA Transcription

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TERRA-Reinforced Association of LSD1 with MRE11 Promotes Processing of Uncapped Telomeres

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Telomeres: The silence is broken

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Telomeric transcripts stimulate telomere recombination to suppress senescence in cells lacking telomerase

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A three-state model for the regulation of telomerase by TERRA and hnRNPA1

Redon, S., Zemp, I., & Lingner, J. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt695 · Cited by 111 · see citing works

Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast

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Deregulated telomere transcription causes replication-dependent telomere shortening and promotes cellular senescence

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TERRA, CpG methylation, and telomere heterochromatin: Lessons from ICF syndrome cells

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Telomerase efficiently elongates highly transcribing telomeres in human cancer cells

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The interface between transcription and mRNP export: From THO to THSC/TREX-2

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Expression of Telomeres in Astrocytoma WHO Grade 2 to 4: TERRA Level Correlates with Telomere Length, Telomerase Activity, and Advanced Clinical Grade

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Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulatorsPreprint

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Structure of Long Human Telomeric RNA (TERRA): G-Quadruplexes Formed by Four and Eight UUAGGG Repeats Are Stable Building Blocks

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Specific Binding of Modified RGG Domain in TLS/FUS to G-Quadruplex RNA: Tyrosines in RGG Domain Recognize 2′-OH of the Riboses of Loops in G-Quadruplex

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The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA

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Post-translational modifications of TRF1 and TRF2 and their roles in telomere maintenance

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The human telomerase RNA component, hTR, activates the DNA-dependent protein kinase to phosphorylate heterogeneous nuclear ribonucleoprotein A1

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Human telomere RNA and DNA form an intermolecular G-quadruplex

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Telomeric RNAs Mark Sex Chromosomes in Stem Cells

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Telomeric Repeat-Containing RNA (TERRA) and Telomerase Are Components of Telomeres During Mammalian Gametogenesis1

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The differential processing of telomeres in response to increased telomeric transcription and RNA–DNA hybrid accumulation

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Structure, function and targeting of human telomere RNA

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TERRA, hnRNP A1, and DNA-PKcs Interactions at Human Telomeres

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Induced pluripotent stem cells as a model for telomeric abnormalities in ICF type I syndrome

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Telomere recombination and alternative telomere lengthening mechanisms

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RPA and POT1

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Telomeric repeat-containing RNA and telomerase in human fetal oocytes

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Telomerase recruitment to telomeres

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The end protection problem—an unexpected twist in the tail

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Long-term Persistent Organic Pollutants Exposure Induced Telomere Dysfunction and Senescence-Associated Secretary Phenotype

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Current and Future Trends of Colorectal Cancer Treatment: Exploring Advances in Immunotherapy

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Telomeres and telomerase in the clinical management of colorectal cancer

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