Broad functional profiling of fission yeast proteins using phenomics and machine learning

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Functional Genomics of Adhesion, Invasion, and Mycelial Formation in Schizosaccharomyces pombe

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The contribution of non-essentialSchizosaccharomyces pombegenes to fitness in response to altered nutrient supply and target of rapamycin activity

Lie, S., Banks, P., Lawless, C., Lydall, D. A., & Petersen, J. (2018) · Open Biology · doi:10.1098/rsob.180015 · Cited by 26 · see citing works

The CCR4-NOT Complex Is Implicated in the Viability of Aneuploid Yeasts

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CREB1 acts via the miR‑922/ARID2 axis to enhance malignant behavior of liver cancer cells

Liu, X., Zhang, H., Zhou, P., Yu, Y., Zhang, H., Chen, L., Gong, J., & Liu, Z. (2021) · Oncology Reports · doi:10.3892/or.2021.8030 · Cited by 25 · see citing works

Identification of New Players in Cell Division, DNA Damage Response, and Morphogenesis Through Construction of Schizosaccharomyces pombe Deletion Strains

Chen, J., Beckley, J. R., McDonald, N. A., Ren, L., Mangione, M. C., Jang, S. J., Elmore, Z. C., Rachfall, N., Feoktistova, A., Jones, C. M., et al. (2015) · G3 Genes Genomes Genetics · doi:10.1534/g3.114.015701 · Cited by 24 · see citing works

High-Throughput Flow Cytometry Combined with Genetic Analysis Brings New Insights into the Understanding of Chromatin Regulation of Cellular Quiescence

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Cell-based screens and phenomics with fission yeast

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Functional profiling of long intergenic non-coding RNAs in fission yeast

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Genome-wide Screening of Regulators of Catalase Expression

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KinFams: De-Novo Classification of Protein Kinases Using CATH Functional Units

Adeyelu, T. T., Bordin, N., Waman, V., Sadlej, M., Sillitoe, I., Moya‐García, A. A., & Orengo, C. A. (2023) · Biomolecules · doi:10.3390/biom13020277 · Cited by 14 · see citing works

High-Throughput, High-Precision Colony Phenotyping with Pyphe

Kamrad, S., Bähler, J., & Ralser, M. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2257-5_21 · Cited by 9 · see citing works

Crystal structure and functional analysis of human C1ORF123

Rahaman, S. N. A., Yusop, J. M., Mohamed‐Hussein, Z., Aizat, W. M., Ho, K. L., Teh, A.-H., Waterman, J., Tan, B. K., Tan, H. L., Li, A. Y., et al. (2018) · PeerJ · doi:10.7717/peerj.5377 · Cited by 7 · see citing works

PomBase: a Global Core Biodata Resource—growth, collaboration, and sustainability

Rutherford, K., Lera-Ramírez, M., & Wood, V. (2024) · Genetics · doi:10.1093/genetics/iyae007 · Cited by 101 · see citing works

Targeted regulation of sterol biosynthesis genes according to perturbations in ergosterol biosynthesis in fungi

Yu, P., Zhou, M., Yu, D., Zhang, Z., Ye, S., Yu, Y., Sun, X., Li, S., & Hu, C. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.01.046 · Cited by 20 · see citing works

Integrating Large-Scale Protein Structure Prediction into Human Genetics Research

Marrero, M. C., Jänes, J., Baptista, D., & Beltrão, P. (2024) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-120622-020615 · Cited by 13 · see citing works

Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast

Bérard, M., Merlini, L., & Martin, S. G. (2024) · PLoS Biology · doi:10.1371/journal.pbio.3002963 · Cited by 13 · see citing works

Integrating yeast biodiversity and machine learning for predictive metabolic engineering

Watcharawipas, A., Runguphan, W., Khamwachirapithak, P., & Laothanachareon, T. (2025) · FEMS Yeast Research · doi:10.1093/femsyr/foaf072 · Cited by 9 · see citing works

Hypoxia-driven lncRNA CTD-2510F5.4: a potential player in hepatocellular carcinoma’s prognostic stratification, cellular behavior, tumor microenvironment, and therapeutic response

Abulihaiti, Z., Li, W., Yang, L., Zhang, H., Du, A., Tang, N., Lu, Y., & Zeng, J. (2024) · Molecular Biology Reports · doi:10.1007/s11033-024-09826-6 · Cited by 5 · see citing works

Dissecting the cell cycle regulation, DNA damage sensitivity and lifespan effects of caffeine in fission yeast

Alao, J. P., Kumar, J., Stamataki, D., & Rallis, C. (2025) · Microbial Cell · doi:10.15698/mic2025.06.852 · Cited by 5 · see citing works

Loss of Gst1 enhances resistance to MMS by reprogramming the transcription of DNA damage response genes in a Rad53-dependent manner in Candida albicans

Cai, H., Feng, Y., Wang, J., Cao, Z., Lv, R., & Feng, J. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01865-7 · Cited by 5 · see citing works

Understanding the molecular mechanisms of human diseases: the benefits of fission yeasts

Ács-Szabó, L., Papp, L. A., & Miklós, I. G. (2024) · Microbial Cell · doi:10.15698/mic2024.08.833 · Cited by 4 · see citing works

The 1-acylglycerol-3-phosphate acyltransferase Slc1 is required to regulate mitochondria and lipid droplets

Zhao, C., Liu, P., Wu, Y., Yan, S., He, J., & Fu, C. (2025) · Microbiological Research · doi:10.1016/j.micres.2025.128080 · Cited by 4 · see citing works

The missing link in FAIR data policy: biodata resources in life sciences

Poveda, L., Farrell, G., Tosatto, S. C. E., Zahn‐Zabal, M., Ruch, P., Gobeill, J., Waterhouse, R. M., & Dessimoz, C. (2026) · Scientific Data · doi:10.1038/s41597-026-06690-w · Cited by 4 · see citing works

Rapalink-1 reveals TOR-dependent genes and an agmatinergic axis-based metabolic feedback regulating TOR activity and lifespan in fission yeast

Kumar, J., Ng, K., & Rallis, C. (2025) · Communications Biology · doi:10.1038/s42003-025-08731-3 · Cited by 3 · see citing works

Characterization of oncohistone H2B variants in Schizosaccharomyces pombe reveals a key role of H2B monoubiquitination deficiency in genomic instability by altering gene expression

Lu, G., Liu, L., Opoku, M., Zhu, R., Wang, H., & Feng, G. (2025) · FEMS Yeast Research · doi:10.1093/femsyr/foaf027 · Cited by 2 · see citing works

Identification of an ERGIC ‐Like Compartment in Fission Yeast: Emp43 Functions as a Lectin‐Like Cargo Receptor for Glycosylated Proteins

Imamura, I., Kawaguchi, S., Suzuki, S., Kamiya, Y., Ohnishi, Y., Ueda, J., Nashiki, K., Takegawa, K., Tabuchi, M., & Tanaka, N. (2025) · Molecular Microbiology · doi:10.1111/mmi.70033 · Cited by 1 · see citing works

A comprehensive review of artificial intelligence as a catalyst in aging research: insights, gaps and future perspectives

Mahbub, T. B., Safaeian, P., & Sohrabi, S. (2026) · Frontiers in Aging · doi:10.3389/fragi.2026.1644669 · Cited by 1 · see citing works

Parallel but distinct adaptive routes in the budding and fission yeasts after 10,000 generations of experimental evolution

N’Guessan, A., Wang, V., Bakerlee, C. W., Belousova, J., Brenna, G., Dillingham, M. E., Dupic, T., Gopalakrishnan, S., Goyal, J., Gupta, M., et al. (2026) · Nature Ecology & Evolution · doi:10.1038/s41559-026-03017-1 · Cited by 1 · see citing works

A time-resolved high-throughput screening of fission yeast deletion mutants for oxidative stress resistance

Pirsalehi, M., Islam, R. A., Ng, K., Xintarakou, O., Thorpe, P. H., & Rallis, C. (2026) · Microbial Cell · doi:10.15698/mic2026.07.884 · Cited by 1 · see citing works

Golgi_traff phylogeny reveals ancient eukaryotic genes with recent surprises: replication and diversification of HID1 domain-containing protein unique to Schizosaccharomyces

Hooks, M. A., Alasmari, A., Alshehri, M., Brocard, L., Hooks, K. B., Julien, M., & McFarlane, R. J. (2025) · FEMS Microbiology Letters · doi:10.1093/femsle/fnaf088 · Cited by 1 · see citing works

Effects of rpl1001 Gene Deletion on Cell Division of Fission Yeast and Its Molecular Mechanism

Yu, W., Yuan, R., Liu, M., Liu, K., Ding, X., & Hou, Y. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46030164 · Cited by 1 · see citing works

Bro1-Mediated Trafficking Couples TOR Signalling to Cellular Metabolism and LongevityPreprint

Ng, K., Kumar, J., Dabrowska, A. F., Clemente-Ramos, J., Islam, R. A., Xintarakou, O., Freiwald, A., Bartel, N., Ludwig, D., Stamataki, D., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.12.698986 · Cited by 1 · see citing works

A systematic screen identifies Saf5 as a link between splicing and transcription in fission yeast

Borao, S., Vega, M., Boronat, S., Hidalgo, E., Hümmer, S., & Ayté, J. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011316

Mitochondrial dysfunction underlies cardiac contractility and growth defects in a zebrafish model of NAA15 -related heart diseasePreprint

Piedade, W. P., Weeks, O., Moran, H. R., Akerberg, A. A., Molnar, M. M., Galdieri, J., Buick, A., Zheng, R., Chen, K., Keshishian, H., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.04.668548

The BUD31 Homologous Gene in Schizosaccharomyces pombe Is Evolutionarily Conserved and Can Be Linked to Cellular Processes Regulated by the TOR Pathway

Vig, I., Ács-Szabó, L., Benkő, Z., Poláková, S., Papp, L. A., Gregáň, J., & Miklós, I. G. (2025) · Cells · doi:10.3390/cells14211736

Electron transport chain disruption leads to failure of glucose derepression via the Snf1/AMPK pathwayPreprint

Lewis, A. G., Smith, J. R., Smardz, M., Sandoval, C. M., Suzuki, S. W., Bennett, B. D., & Gibney, P. A. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.11.06.687039

HID1 domain-containing protein 1 is required for normal cell proliferation in Schizosaccharomyces pombePreprint

Fritsche, A.-P., Alasmari, A., Alshehri, M., Claverol, S., Fuller, H. R., McFarlane, R. J., & Hooks, M. A. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.02.691498

Compromised ESCRT signalling is sufficient for resistance to the Target of Rapamycin Complex inhibitor Torin1 in fission yeastPreprint

Alao, J. P., Islam, R. A., Toyoda, Y., Saitoh, S., & Rallis, C. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.23.696270

Genetic and environmental determinants of multicellular-like phenotypes in fission yeast

Kövér, B., Cohen, C. E., Seres, L., Raut, S., Ralser, M., Heineike, B. M., & Bähler, J. (2026) · Genetics · doi:10.1093/genetics/iyag064

Mixing Is Dispensable for Optical Density-Based High-Throughput Growth Screening Assay in Fission Yeast

Lim, K. K., Chung, J. J., Ma, S., Yen, C.-C., Zhang, L., & Chen, E. S. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27083410

Bridging Manual and Computational Approaches: The Pseudophosphatase Scanner for Genome-Wide Fungal Pseudophosphatome Analysis

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Pangenome and genome-scale essentiality in the emerging fungal pathogen Candidozyma aurisPreprint

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Humanization of the rpb9 Locus in Fission Yeast Reveals Conserved and Divergent Roles of rpb9 and Human POLR2I

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Glutathione acts as an exometabolite that promotes growth recovery in fission yeast with defects in amino acid metabolism and cell polarity

Yoshizumi, R., Miura, S., Matoba, H., Hirai, G., Asamizu, S., Onaka, H., Yashiroda, Y., Matsuyama, A., Yoshida, M., & Nishimura, S. (2026) · mSystems · doi:10.1128/msystems.00123-26

Mining Phenotypes for Protein Function Prediction

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Broad network-based predictability of Saccharomyces cerevisiaegene loss-of-function phenotypes

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Genome-Scale Gene Function Prediction Using Multiple Sources of High-Throughput Data in Yeast Saccharomyces cerevisiae

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Combining views for newly sequenced organisms

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FunPred 3.0: improved protein function prediction using protein interaction network

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