Young, Lawrence H.

Pioglitazone after Ischemic Stroke or Transient Ischemic Attack

Kernan, W. N., Viscoli, C. M., Furie, K. L., Young, L. H., Inzucchi, S. E., Gorman, M., Guarino, P. D., Lovejoy, A. M., Peduzzi, P. N., Conwit, R., et al. (2016) · New England Journal of Medicine

Acute Ischemic Stroke ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 1,124

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

Zong, H., Ren, J. M., Young, L. H., Pypaert, M., Mu, J., Birnbaum, M. J., & Shulman, G. I. (2002) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 1,036

Cardiac Outcomes After Screening for Asymptomatic Coronary Artery Disease in Patients With Type 2 Diabetes: The DIAD Study: A Randomized Controlled Trial

Young, L. H., Wackers, F. J. T., Chyun, D. A., Davey, J. A., Barrett, E. J., Taillefer, R., Heller, G. V., Iskandrian, A. E., Wittlin, S. D., Filipchuk, N., et al. (2009) · JAMA

Cardiac Imaging and DiagnosticsDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 809

AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury

Russell, R. R., Li, J., Coven, D. L., Pypaert, M., Zechner, C., Palmeri, M., Giordano, F. J., Mu, J., Birnbaum, M. J., & Young, L. H. (2004) · Journal of Clinical Investigation

Cardiac Ischemia and ReperfusionMetabolism, Diabetes, and Cancer

Cited by 738

Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis

Bergeron, R., Ren, J. M., Cadman, K. S., Moore, I. K., Perret, P., Pypaert, M., Young, L. H., Semenkovich, C. F., & Shulman, G. I. (2001) · American Journal of Physiology-Endocrinology and Metabolism

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 561

Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis

Reznick, R. M., Zong, H., Li, J., Morino, K., Moore, I. K., Yu, H. J., Liu, Z.-X., Dong, J., Mustard, K. J., Hawley, S. A., et al. (2007) · Cell Metabolism

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 555

GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance

Luan, H. H., Wang, A., Hilliard, B. K., Carvalho, F., Rosen, C. E., Ahasic, A. M., Herzog, E. L., Kang, I., Pisani, M. A., Yu, S., et al. (2019) · Cell

GDF15 and Related BiomarkersSepsis Diagnosis and Treatment

Cited by 527

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart

Miller, E. J., Li, J., Leng, L., McDonald, C., Atsumi, T., Bucala, R., & Young, L. H. (2008) · Nature

Macrophage Migration Inhibitory FactorCardiac Ischemia and Reperfusion

Cited by 429

AMP-activated protein kinase regulation and biological actions in the heart

Zaha, V. G., & Young, L. H. (2012) · Circulation Research

Metabolism, Diabetes, and CancerCardiovascular Function and Risk Factors

Cited by 279

Screening for coronary artery disease in patients with diabetes

Bax, J. J., Young, L. H., Frye, R. L., Bonow, R. O., Steinberg, H. O., & Barrett, E. J. (2007) · Diabetes Care

Cardiac Imaging and DiagnosticsDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 251

Resolution of Asymptomatic Myocardial Ischemia in Patients With Type 2 Diabetes in the Detection of Ischemia in Asymptomatic Diabetics (DIAD) Study

Wackers, F. J. T., Chyun, D. A., Young, L. H., Heller, G. V., Iskandrian, A. E., Davey, J. A., Barrett, E. J., Taillefer, R., Wittlin, S. D., Filipchuk, N., et al. (2007) · Diabetes Care

Cardiac Imaging and DiagnosticsCardiovascular Function and Risk Factors

Cited by 137

Pioglitazone and Risk for Bone Fracture: Safety Data from a Randomized Clinical Trial

Viscoli, C. M., Inzucchi, S. E., Young, L. H., Insogna, K. L., Conwit, R., Furie, K. L., Gorman, M., Kelly, M. A., Lovejoy, A. M., Kernan, W. N., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism

Bone health and osteoporosis researchDiabetes Treatment and Management

Cited by 124

Pioglitazone Therapy in Patients With Stroke and Prediabetes: A Post Hoc Analysis of the IRIS Randomized Clinical Trial

Spence, J. D., Viscoli, C. M., Inzucchi, S. E., Dearborn-Tomazos, J., Ford, G. A., Gorman, M., Furie, K. L., Lovejoy, A. M., Young, L. H., Kernan, W. N., et al. (2019) · JAMA Neurology

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 109

AMP-activated protein kinase conducts the ischemic stress response orchestra

Young, L. H. (2008) · Circulation

Metabolism, Diabetes, and CancerCardiac Ischemia and Reperfusion

Cited by 82

Cardiac Outcomes After Ischemic Stroke or Transient Ischemic Attack: Effects of Pioglitazone in Patients With Insulin Resistance Without Diabetes Mellitus

Young, L. H., Viscoli, C. M., Curtis, J. P., Inzucchi, S. E., Schwartz, G. G., Lovejoy, A. M., Furie, K. L., Gorman, M. J., Conwit, R., Abbott, J. D., et al. (2017) · Circulation

Diabetes, Cardiovascular Risks, and LipoproteinsAcute Ischemic Stroke Management

Cited by 66

Pioglitazone for secondary prevention after ischemic stroke and transient ischemic attack: Rationale and design of the Insulin Resistance Intervention after Stroke Trial

Viscoli, C. M., Brass, L. M., Carolei, A., Conwit, R., Ford, G. A., Furie, K. L., Gorman, M., Guarino, P. D., Inzucchi, S. E., Lovejoy, A. M., et al. (2014) · American Heart Journal

Diabetes, Cardiovascular Risks, and LipoproteinsAcute Ischemic Stroke Management

Cited by 50