Ingber, Donald E.

Matched-comparative modeling of normal and diseased human airway responses using a microengineered breathing lung chip

Benam, K. H., Novak, R., Nawroth, J., Hirano-Kobayashi, M., Ferrante, T. C., Choe, Y., Prantil-Baun, R., Weaver, J. C., Bahinski, A., Parker, K. K., et al. (2016) · Cell Systems

Chronic Obstructive Pulmonary Disease (COPD) Research3D Printing in Biomedical Research

Cited by 309

Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities

Maoz, B. M., Herland, A., Henry, O. Y. F., Leineweber, W. D., Yadid, M., Doyle, J., Mannix, R., Kujala, V. J., FitzGerald, E. A., Parker, K. K., et al. (2017) · Lab on a Chip

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 266

Mechanotransduction of fluid stresses governs 3D cell migration

Polacheck, W. J., German, A. E., Mammoto, A., Ingber, D. E., & Kamm, R. D. (2014) · Proceedings of the National Academy of Sciences

Cellular Mechanics and InteractionsCell Adhesion Molecules Research

Cited by 265

Human Colon-on-a-Chip Enables Continuous In Vitro Analysis of Colon Mucus Layer Accumulation and Physiology

Sontheimer-Phelps, A., Chou, D. B., Tovaglieri, A., Ferrante, T. C., Duckworth, T., Fadel, C., Frismantas, V., Sutherland, A. D., Jalili-Firoozinezhad, S., Kasendra, M., et al. (2020) · Cellular and Molecular Gastroenterology and Hepatology

3D Printing in Biomedical ResearchInflammatory Bowel Disease

Cited by 239

Analysis of Cell Mechanics in Single Vinculin-Deficient Cells Using a Magnetic Tweezer

Alenghat, F. J., Fabry, B., Tsai, K. Y., Goldmann, W. H., & Ingber, D. E. (2000) · Biochemical and Biophysical Research Communications

Cellular Mechanics and InteractionsForce Microscopy Techniques and Applications

Cited by 216

Reverse engineering human pathophysiology with organs-on-chips

Ingber, D. E. (2016) · Cell

3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Cited by 212

Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip

Jalili-Firoozinezhad, S., Prantil-Baun, R., Jiang, A., Potla, R., Mammoto, T., Weaver, J. C., Ferrante, T. C., Kim, H. J., Cabral, J. M. S., Levy, O., et al. (2018) · Cell Death & Disease

Effects of Radiation Exposure3D Printing in Biomedical Research

Cited by 209

Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems

Odijk, M., van der Meer, A. D., Levner, D., Kim, H. J., van der Helm, M. W., Segerink, L. I., Frimat, J.-P., Hamilton, G. A., Ingber, D. E., & van den Berg, A. (2015) · Lab on a Chip

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 209

Human Intestinal Morphogenesis Controlled by Transepithelial Morphogen Gradient and Flow-Dependent Physical Cues in a Microengineered Gut-on-a-Chip

Shin, W., Hinojosa, C. D., Ingber, D. E., & Kim, H. J. (2019) · iScience

3D Printing in Biomedical ResearchCellular Mechanics and Interactions

Cited by 186

A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function

Jain, A., Graveline, A., Waterhouse, A., Vernet, A., Flaumenhaft, R., & Ingber, D. E. (2016) · Nature Communications

Blood properties and coagulationBlood Coagulation and Thrombosis Mechanisms

Cited by 182

Physiologically based pharmacokinetic and pharmacodynamic analysis enabled by microfluidically linked organs-on-chips

Prantil-Baun, R., Novak, R., Das, D., Somayaji, M. R., Przekwas, A., & Ingber, D. E. (2018) · Annual Review of Pharmacology and Toxicology

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 176

Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip

Bai, H., Si, L., Jiang, A., Belgur, C., Zhai, Y., Plebani, R., Oh, C. Y., Rodas, M., Patil, A., Nurani, A., et al. (2022) · Nature Communications

Respiratory Support and MechanismsInfluenza Virus Research Studies

Cited by 171

Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy

Adapala, R. K., Thoppil, R. J., Ghosh, K., Cappelli, H. C., Dudley, A. C., Paruchuri, S., Keshamouni, V, Klagsbrun, M., Meszaros, J. G., Chilian, W. M., et al. (2016) · Oncogene

Angiogenesis and VEGF in CancerIon Channels and Receptors

Cited by 153

Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium

Jain, A., van der Meer, A. D., Papa, A.-L., Barrile, R., Lai, A., Schlechter, B. L., Otieno, M. A., Louden, C. S., Hamilton, G. A., Michelson, A. D., et al. (2016) · Biomedical Microdevices

Platelet Disorders and TreatmentsBlood properties and coagulation

Cited by 148

Organ‐on‐Chip recapitulates thrombosis induced by an anti‐CD154 monoclonal antibody: translational potential of advanced microengineered systems

Barrile, R., van der Meer, A. D., Park, H., Fraser, J. P., Simic, D., Teng, F., Conegliano, D., Nguyen, J., Jain, A., Zhou, M., et al. (2018) · Clinical Pharmacology & Therapeutics

3D Printing in Biomedical ResearchBlood Coagulation and Thrombosis Mechanisms

Cited by 138

Simulating drug concentrations in PDMS microfluidic organ chips

Grant, J., Özkan, A., Oh, C., Mahajan, G., Prantil-Baun, R., & Ingber, D. E. (2021) · Lab on a Chip

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 133

Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip

Bein, A., Kim, S., Goyal, G., Cao, W., Fadel, C., Naziripour, A., Sharma, S., Swenor, B., LoGrande, N., Nurani, A., et al. (2021) · Frontiers in Pharmacology

3D Printing in Biomedical ResearchSARS-CoV-2 and COVID-19 Research

Cited by 83

Extracellular matrix controls tubulin monomer levels in hepatocytes by regulating protein turnover.

Mooney, D. J., Hansen, L. K., Langer, R., Vacanti, J. P., & Ingber, D. E. (1994) · Molecular Biology of the Cell

Microtubule and mitosis dynamicsCellular Mechanics and Interactions

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Synaptic reorganization in scaled networks of controlled size.

Wilson, N. R., Ty, M. T., Ingber, D. E., Sur, M., & Liu, G. (2007) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

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Application of a Halbach magnetic array for long-range cell and particle separations in biological samples

Kang, J. H., Driscoll, H., Super, M., & Ingber, D. E. (2016) · Applied Physics Letters

Microfluidic and Bio-sensing TechnologiesCharacterization and Applications of Magnetic Nanoparticles

Cited by 21