Mantzoros, Christos S.

Role of leptin in the neuroendocrine response to fasting

Ahima, R. S., Prabakaran, D., Mantzoros, C., Qu, D., Lowell, B., Maratos-Flier, E., & Flier, J. S. (1996) · Nature

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 3,117

Adverse metabolic and cardiovascular consequences of circadian misalignment

Scheer, F. A. J. L., Hilton, M. F., Mantzoros, C. S., & Shea, S. A. (2009) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninSleep and Work-Related Fatigue

Cited by 2,351

Obesity and cancer risk: Emerging biological mechanisms and perspectives

Avgerinos, K. I., Spyrou, N., Mantzoros, C. S., & Dalamaga, M. (2019) · Metabolism

Cancer Risks and FactorsAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,567

A 2022 update on the epidemiology of obesity and a call to action: As its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on

Boutari, C., & Mantzoros, C. S. (2022) · Metabolism

Obesity, Physical Activity, DietObesity and Health Practices

Cited by 1,068

FNDC5 and Irisin in Humans: I. Predictors of Circulating Concentrations in Serum and Plasma and II. mRNA Expression and Circulating Concentrations in Response to Weight Loss and Exercise

Huh, J. Y., Panagiotou, G., Mougios, V., Brinkoetter, M., Vamvini, M. T., Schneider, B. E., & Mantzoros, C. S. (2012) · Metabolism

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,040

Mediterranean diet and incidence of and mortality from coronary heart disease and stroke in women

Fung, T. T., Rexrode, K. M., Mantzoros, C. S., Manson, J. E., Willett, W. C., & Hu, F. B. (2009) · Circulation

Nutritional Studies and DietCardiovascular Health and Risk Factors

Cited by 916

Recombinant human leptin in women with hypothalamic amenorrhea

Welt, C. K., Chan, J. L., Bullen, J., Murphy, R., Smith, P., DePaoli, A. M., Karalis, A., & Mantzoros, C. S. (2004) · New England Journal of Medicine

Hypothalamic control of reproductive hormonesRegulation of Appetite and Obesity

Cited by 908

The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men

Chan, J. L., Heist, K., DePaoli, A. M., Veldhuis, J. D., & Mantzoros, C. S. (2003) · Journal of Clinical Investigation

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 697

Human Leptin Levels Are Pulsatile and Inversely Related to Pituitary–Ardenal Function

Licinio, J., Mantzoros, C., Negrão, A. B., Cizza, G., Wong, M.-L., Bongiorno, P. B., Chrousos, G. P., Karp, B., Allen, C., Flier, J. S., et al. (1997) · Nature Medicine

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 632

Physiology and role of irisin in glucose homeostasis

Perakakis, N., Triantafyllou, G. A., Fernández-Real, J. M., Huh, J. Y., Park, K. H., Seufert, J., & Mantzoros, C. S. (2017) · Nature Reviews Endocrinology

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 621

Clinical care pathway for the risk stratification and management of patients with nonalcoholic fatty liver disease

Kanwal, F., Shubrook, J. H., Adams, L. A., Pfotenhauer, K., Wai-Sun Wong, V., Wright, E., Abdelmalek, M. F., Harrison, S. A., Loomba, R., Mantzoros, C. S., et al. (2021) · Gastroenterology

Liver Disease Diagnosis and TreatmentLiver Diseases and Immunity

Cited by 618

Leptin in Human Physiology and Pathophysiology

Mantzoros, C. S., Magkos, F., Brinkoetter, M., Sienkiewicz, E., Dardeno, T. A., Kim, S.-Y., Hamnvik, O.-P. R., & Koniaris, A. (2011) · American Journal of Physiology-Endocrinology and Metabolism

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 593

Non-alcoholic fatty liver disease and dyslipidemia: An update

Katsiki, N., Mikhailidis, D. P., & Mantzoros, C. S. (2016) · Metabolism

Liver Disease Diagnosis and TreatmentDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 564

Leptin and reproduction: a review

Moschos, S., Chan, J. L., & Mantzoros, C. S. (2002) · Fertility and Sterility

Hypothalamic control of reproductive hormonesRegulation of Appetite and Obesity

Cited by 557

Pharmacotherapy of obesity: an update on the available medications and drugs under investigation

Chakhtoura, M., Haber, R., Ghezzawi, M., Rhayem, C., Tcheroyan, R., & Mantzoros, C. S. (2023) · eClinicalMedicine

Pharmacology and Obesity TreatmentRegulation of Appetite and Obesity

Cited by 462

Role of leptin in energy-deprivation states: normal human physiology and clinical implications for hypothalamic amenorrhoea and anorexia nervosa.

Chan, J. L., & Mantzoros, C. S. (2005) · The Lancet

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 382

Drug Insight: the role of leptin in human physiology and pathophysiology—emerging clinical applications

Brennan, A. M., & Mantzoros, C. S. (2006) · Nature Clinical Practice Endocrinology & Metabolism

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 374

Exercise-induced irisin secretion is independent of age or fitness level and increased irisin may directly modulate muscle metabolism through AMPK activation

Huh, J. Y., Mougios, V., Kabasakalis, A., Fatouros, I., Siopi, A., Douroudos, I. I., Filippaios, A., Panagiotou, G., Park, K. H., & Mantzoros, C. S. (2014) · The Journal of Clinical Endocrinology & Metabolism

Adipose Tissue and MetabolismExercise and Physiological Responses

Cited by 363

Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans

Huh, J. Y., Dincer, F., Mesfum, E., & Mantzoros, C. S. (2014) · International Journal of Obesity

Adipose Tissue and MetabolismMuscle Physiology and Disorders

Cited by 309

A Longitudinal Assessment of Hormonal and Physical Alterations during Normal Puberty in Boys. V. Rising Leptin Levels May Signal the Onset of Puberty

Mantzoros, C. S. (1997) · Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesHormonal and reproductive studies

Cited by 300

Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: Associations with metabolic parameters and insulin resistance and regulation by physical training

Blüher, M., Bullen, J. W., Lee, J. H., Kralisch, S., Fasshauer, M., Klöting, N., Niebauer, J., Schön, M. R., Williams, C. J., & Mantzoros, C. S. (2006) · The Journal of Clinical Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 293

GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue liraglutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-controlled trial

Farr, O. M., Sofopoulos, M., Tsoukas, M. A., Dincer, F., Thakkar, B., Sahin-Efe, A., Filippaios, A., Bowers, J., Srnka, A., Gavrieli, A., et al. (2016) · Diabetologia

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 287

Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women

Licinio, J., Negrão, A. B., Mantzoros, C., Kaklamani, V., Wong, M.-L., Bongiorno, P. B., Mulla, A., Cearnal, L., Veldhuis, J. D., Flier, J. S., et al. (1998) · Proceedings of the National Academy of Sciences

Hypothalamic control of reproductive hormonesOvarian function and disorders

Cited by 287

Leptin is an effective treatment for hypothalamic amenorrhea

Chou, S. H., Chamberland, J. P., Liu, X., Matarese, G., Gao, C., Stefanakis, R., Brinkoetter, M. T., Gong, H., Arampatzi, K., & Mantzoros, C. S. (2011) · Proceedings of the National Academy of Sciences

Hypothalamic control of reproductive hormonesRegulation of Appetite and Obesity

Cited by 287