Peltonen, Leena

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

The UK PBC Consortium, Mells, G. F., The Wellcome Trust Case Control Consortium 3, Floyd, J. A. B., Morley, K. I., Cordell, H. J., Franklin, C. S., Shin, S.-Y., Heneghan, M. A., Neuberger, J. M., et al. (2011) · Nature Genetics

Liver Diseases and ImmunityGenetic Associations and Epidemiology

Cited by 464

Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts

Paloneva, J., Kestilä, M., Wu, J., Salminen, A., Böhling, T., Ruotsalainen, V., Hakola, P., Bakker, A. B. H., Phillips, J. H., Pekkarinen, P., et al. (2000) · Nature Genetics

Genomics and Rare DiseasesBone Metabolism and Diseases

Cited by 460

Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease

Waterworth, D. M., Ricketts, S. L., Song, K., Chen, L., Zhao, J. H., Ripatti, S., Aulchenko, Y. S., Zhang, W., Yuan, X., Lim, N., et al. (2010) · Arteriosclerosis, Thrombosis, and Vascular Biology

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 405

Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD

Saccone, N. L., Culverhouse, R. C., Schwantes-An, T.-H., Cannon, D. S., Chen, X., Cichon, S., Giegling, I., Han, S., Han, Y., Keskitalo-Vuokko, K., et al. (2010) · PLoS Genetics

Smoking Behavior and CessationGenetic Associations and Epidemiology

Cited by 395

Circadian clock-related polymorphisms in seasonal affective disorder and their relevance to diurnal preference

Johansson, C., Willeit, M., Smedh, C., Ekholm, J., Paunio, T., Kieseppä, T., Lichtermann, D., Praschak-Rieder, N., Neumeister, A., Nilsson, L.-G., et al. (2003) · Neuropsychopharmacology

Circadian rhythm and melatoninGenetic Associations and Epidemiology

Cited by 341

Association of DISC1/TRAX Haplotypes With Schizophrenia, Reduced Prefrontal Gray Matter, and Impaired Short- and Long-term Memory

Cannon, T. D., Hennah, W., van Erp, T. G. M., Thompson, P. M., Lonnqvist, J., Huttunen, M., Gasperoni, T., Tuulio-Henriksson, A., Pirkola, T., Toga, A. W., et al. (2005) · Archives of General Psychiatry

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 337

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Kilpeläinen, T. O., Zillikens, M. C., Stančákova, A., Finucane, F. M., Ried, J. S., Langenberg, C., Zhang, W., Beckmann, J. S., Luan, J., Vandenput, L., et al. (2011) · Nature Genetics

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 335

Alternative splicing of human elastin mRNA indicated by sequence analysis of cloned genomic and complementary DNA.

Indik, Z., Yeh, H., Ornstein-Goldstein, N., Sheppard, P., Anderson, N., Rosenbloom, J. C., Peltonen, L., & Rosenbloom, J. (1987) · Proceedings of the National Academy of Sciences

RNA Research and SplicingConnective tissue disorders research

Cited by 334

Genetic evidence of assortative mating in humans

Robinson, M. R., Kleinman, A., Graff, M., Vinkhuyzen, A. A. E., Couper, D., Miller, M. B., Peyrot, W. J., Abdellaoui, A., Zietsch, B. P., Nolte, I. M., et al. (2017) · Nature Human Behaviour

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 326

DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features

Paloneva, J., Mandelin, J., Kiialainen, A., Böhling, T., Prudlo, J., Hakola, P., Haltia, M., Konttinen, Y. T., & Peltonen, L. (2003) · The Journal of Experimental Medicine

Bone Metabolism and DiseasesImmunodeficiency and Autoimmune Disorders

Cited by 318

Childhood adversities are associated with shorter telomere length at adult age both in individuals with an anxiety disorder and controls

Kananen, L., Surakka, I., Pirkola, S., Suvisaari, J., Lönnqvist, J., Peltonen, L., Ripatti, S., & Hovatta, I. (2010) · PLoS ONE

Telomeres, Telomerase, and SenescenceChild Abuse and Trauma

Cited by 270

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene ( AUTS2 ) in the regulation of alcohol consumption

Schumann, G., Coin, L. J., Lourdusamy, A., Charoen, P., Berger, K. H., Stacey, D., Desrivières, S., Aliev, F. A., Khan, A. A., Amin, N., et al. (2011) · Proceedings of the National Academy of Sciences

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 264

Copy number variations of chromosome 16p13.1 region associated with schizophrenia

Ingason, A., Rujescu, D., Cichon, S., Sigurdsson, E., Sigmundsson, T., Pietiläinen, O. P. H., Buizer-Voskamp, J. E., Strengman, E., Francks, C., Muglia, P., et al. (2011) · Molecular Psychiatry

Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment

Cited by 258

The genetic causes of basal ganglia calcification, dementia, and bone cysts: DAP12 and TREM2

Klünemann, H. H., Ridha, B. H., Magy, L., Wherrett, J. R., Hemelsoet, D. M., Keen, R. W., De Bleecker, J. L., Rossor, M. N., Marienhagen, J., Klein, H. E., et al. (2005) · Neurology

Neurological diseases and metabolismNeuroinflammation and Neurodegeneration Mechanisms

Cited by 254

Genome-wide Association Study in a High-Risk Isolate for Multiple Sclerosis Reveals Associated Variants in STAT3 Gene

Jakkula, E., Leppä, V., Sulonen, A.-M., Varilo, T., Kallio, S., Kemppinen, A., Purcell, S., Koivisto, K., Tienari, P., Sumelahti, M.-L., et al. (2010) · The American Journal of Human Genetics

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 245

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

the CARDIoGRAM Consortium, Bis, J. C., Kavousi, M., Franceschini, N., Isaacs, A., Abecasis, G. R., Schminke, U., Post, W. S., Smith, A. V., Cupples, L. A., et al. (2011) · Nature Genetics

Genetic Associations and EpidemiologyCardiovascular Health and Disease Prevention

Cited by 212

Sweet taste preferences are partly genetically determined: Identification of a trait locus on chromosome 16

Keskitalo, K., Knaapila, A., Kallela, M., Palotie, A., Wessman, M., Sammalisto, S., Peltonen, L., Tuorila, H., & Perola, M. (2007) · The American Journal of Clinical Nutrition

Biochemical Analysis and Sensing TechniquesGenetic Associations and Epidemiology

Cited by 195

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Voight, B. F., Peloso, G. M., Orho-Melander, M., Frikke-Schmidt, R., Barbalic, M., Jensen, M. K., Hindy, G., Hólm, H., Ding, E. L., Johnson, T., et al. (2012) · The Lancet

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 148

Dap12 and Trem2, molecules involved in innate immunity and neurodegeneration, are co-expressed in the CNS

Kiialainen, A., Hovanes, K., Paloneva, J., Kopra, O., & Peltonen, L. (2005) · Neurobiology of Disease

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 114

Maternally Derived Microduplications at 15q11-q13: Implication of Imprinted Genes in Psychotic Illness

Ingason, A., Kirov, G., Giegling, I., Hansen, T., Isles, A. R., Jakobsen, K. D., Kristinsson, K. T., le Roux, L., Gustafsson, O., Craddock, N., et al. (2011) · American Journal of Psychiatry

Genomic variations and chromosomal abnormalitiesGenetic Syndromes and Imprinting

Cited by 114

Lessons from studying monogenic disease for common disease

Peltonen, L., Perola, M., Naukkarinen, J., & Palotie, A. (2006) · Human Molecular Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 105

Brief report: validity of Finnish registry‐based diagnoses of autism with the ADI‐R

Lampi, K., Sourander, A., Gissler, M., Niemelä, S., Rehnström, K., Pulkkinen, E., Peltonen, L., & Von Wendt, L. (2010) · Acta Paediatrica

Autism Spectrum Disorder ResearchChild Nutrition and Feeding Issues

Cited by 91

Distinct Variants at LIN28B Influence Growth in Height from Birth to Adulthood

Widén, E., Ripatti, S., Cousminer, D. L., Surakka, I., Lappalainen, T., Järvelin, M.-R., Eriksson, J. G., Raitakari, O., Salomaa, V., Sovio, U., et al. (2010) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyHypothalamic control of reproductive hormones

Cited by 88

Acquired obesity and poor physical fitness impair expression of genes of mitochondrial oxidative phosphorylation in monozygotic twins discordant for obesity

Mustelin, L., Pietiläinen, K. H., Rissanen, A., Sovijärvi, A. R., Piirilä, P., Naukkarinen, J., Peltonen, L., Kaprio, J., & Yki-Järvinen, H. (2008) · American Journal of Physiology-Endocrinology and Metabolism

Adipose Tissue and MetabolismGenetics and Physical Performance

Cited by 85