Geiger, Hartmut

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells

Walter, D., Lier, A., Geiselhart, A., Thalheimer, F. B., Huntscha, S., Sobotta, M. C., Moehrle, B., Brocks, D., Bayindir, I., Kaschutnig, P., et al. (2015) · Nature

Hematopoietic Stem Cell TransplantationDNA Repair Mechanisms

Cited by 619

The ageing haematopoietic stem cell compartment

Geiger, H., de Haan, G., & Florian, M. C. (2013) · Nature Reviews Immunology

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 604

Impaired immune surveillance accelerates accumulation of senescent cells and aging

Ovadya, Y., Landsberger, T., Leins, H., Vadai, E., Gal, H., Biran, A., Yosef, R., Sagiv, A., Agrawal, A., Shapira, A., et al. (2018) · Nature Communications

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 578

Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation

Florian, M. C., Dörr, K., Niebel, A., Daria, D., Schrezenmeier, H., Rojewski, M., Filippi, M.-D., Hasenberg, A., Gunzer, M., Scharffetter-Kochanek, K., et al. (2012) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 564

Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors

Haas, S., Hansson, J., Klimmeck, D., Loeffler, D., Velten, L., Uckelmann, H., Wurzer, S., Prendergast, Á. M., Schnell, A., Hexel, K., et al. (2015) · Cell Stem Cell

Platelet Disorders and TreatmentsHematopoietic Stem Cell Transplantation

Cited by 471

Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy

Cabezas-Wallscheid, N., Buettner, F., Sommerkamp, P., Klimmeck, D., Ladel, L., Thalheimer, F. B., Pastor-Flores, D., Roma, L. P., Renders, S., Zeisberger, P., et al. (2017) · Cell

Hematopoietic Stem Cell TransplantationRetinoids in leukemia and cellular processes

Cited by 454

A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing

Florian, M. C., Nattamai, K. J., Dörr, K., Marka, G., Überle, B., Vas, V., Eckl, C., Andrä, I., Schiemann, M., Oostendorp, R. A. J., et al. (2013) · Nature

Hematopoietic Stem Cell TransplantationWnt/β-catenin signaling in development and cancer

Cited by 303

Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells

Nalapareddy, K., Nattamai, K. J., Kumar, R. S., Karns, R., Wikenheiser-Brokamp, K. A., Sampson, L. L., Mahe, M. M., Sundaram, N., Yacyshyn, M.-B., Yacyshyn, B., et al. (2017) · Cell Reports

Wnt/β-catenin signaling in development and cancerGenetics, Aging, and Longevity in Model Organisms

Cited by 280

The aging of lympho-hematopoietic stem cells

Geiger, H., & Van Zant, G. (2002) · Nature Immunology

Hematopoietic Stem Cell TransplantationGenetics, Aging, and Longevity in Model Organisms

Cited by 233

Haematopoietic stem cells in perisinusoidal niches are protected from ageing

Saçma, M., Pospiech, J., Bogeska, R., de Back, W., Mallm, J.-P., Sakk, V., Soller, K., Marka, G., Vollmer, A., Karns, R., et al. (2019) · Nature Cell Biology

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 133

Immunoaging induced by hematopoietic stem cell aging

Wang, J., Geiger, H., & Rudolph, K. L. (2011) · Current Opinion in Immunology

Hematopoietic Stem Cell TransplantationTelomeres, Telomerase, and Senescence

Cited by 107

Aged murine hematopoietic stem cells drive aging-associated immune remodeling

Leins, H., Mulaw, M., Eiwen, K., Sakk, V., Liang, Y., Denkinger, M., Geiger, H., & Schirmbeck, R. (2018) · Blood

Hematopoietic Stem Cell TransplantationT-cell and B-cell Immunology

Cited by 95

Aging of the microenvironment influences clonality in hematopoiesis

Vas, V., Senger, K., Dörr, K., Niebel, A., & Geiger, H. (2012) · PLoS ONE

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 83

Persistent JunB activation in fibroblasts disrupts stem cell niche interactions enforcing skin aging

Maity, P., Singh, K., Krug, L., Koroma, A., Hainzl, A., Bloch, W., Kochanek, S., Wlaschek, M., Schorpp-Kistner, M., Angel, P., et al. (2021) · Cell Reports

Telomeres, Telomerase, and SenescenceSkin Protection and Aging

Cited by 56

The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress

Daria, D., Filippi, M.-D., Knudsen, E. S., Faccio, R., Li, Z., Kalfa, T., & Geiger, H. (2008) · Blood

Hematopoietic Stem Cell TransplantationBlood disorders and treatments

Cited by 46

Quantitative determination of changes in the spatial distribution of components in single cells with CellDetail

Geiger, H., Schuster, T., Amoah, A., Marka, G., Niemann, J., Sacma, M., Sakk, V., Soller, K., Vogel, M., & Vollmer, A. (2024) · Nature Communications

Cell Image Analysis TechniquesAdvanced Fluorescence Microscopy Techniques

Cited by 7

Quantitative determination of the spatial distribution of components in single cells with CellDetail

Schuster, T., Amoah, A., Vollmer, A., Marka, G., Niemann, J., Saçma, M., Sakk, V., Soller, K., Vogel, M., Grigoryan, A., et al. (2024) · Nature Communications

Cell Image Analysis TechniquesAdvanced Fluorescence Microscopy Techniques

Cited by 7