Bennett, David A.

The epigenome in Alzheimer’s disease: current state and approaches for a new path to gene discovery and understanding disease mechanism

Klein, H.-U., Bennett, D. A., & De Jager, P. L. (2016) · Acta Neuropathologica

Epigenetics and DNA MethylationAlzheimer's disease research and treatments

Cited by 49

Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology

Yang, H.-S., White, C. C., Klein, H.-U., Yu, L., Gaiteri, C., Ma, Y., Felsky, D., Mostafavi, S., Petyuk, V. A., Sperling, R. A., et al. (2020) · Neuron

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 47

Cerebrospinal Fluid Tau Cleaved by Caspase-6 Reflects Brain Levels and Cognition in Aging and Alzheimer Disease

Ramcharitar, J., Albrecht, S., Afonso, V. M., Kaushal, V., Bennett, D. A., & LeBlanc, A. C. (2013) · Journal of Neuropathology & Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 47

Neuronal C/EBPβ/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression

Xia, Y., Qadota, H., Wang, Z.-H., Liu, P., Liu, X., Ye, K. X., Matheny, C. J., Berglund, K., Yu, S. P., Drake, D., et al. (2022) · Science Advances

Genetics, Aging, and Longevity in Model OrganismsAlzheimer's disease research and treatments

Cited by 46

Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in A β and TAU proteostasis

Sullivan, S. E., Liao, M., Smith, R. V., White, C., Lagomarsino, V. N., Xu, J., Taga, M., Bennett, D. A., De Jager, P. L., & Young-Pearse, T. L. (2019) · Human Molecular Genetics

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 44

Bulk and Single-Nucleus Transcriptomics Highlight Intra-Telencephalic and Somatostatin Neurons in Alzheimer’s Disease

Consens, M. E., Chen, Y., Menon, V., Wang, Y., Schneider, J. A., De Jager, P. L., Bennett, D. A., Tripathy, S. J., & Felsky, D. (2022) · Frontiers in Molecular Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 44

Alzheimer's disease can spare local metacognition despite global anosognosia: Revisiting the confidence–accuracy relationship in episodic memory

Gallo, D. A., Cramer, S. J., Wong, J. T., & Bennett, D. A. (2012) · Neuropsychologia

Memory Processes and InfluencesDementia and Cognitive Impairment Research

Cited by 43

cindr, the Drosophila Homolog of the CD2AP Alzheimer’s Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis

Ojelade, S. A., Lee, T. V., Giagtzoglou, N., Yu, L., Ugur, B., Li, Y., Duraine, L., Zuo, Z., Petyuk, V., De Jager, P. L., et al. (2019) · Cell Reports

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 42

Grey matter correlates of susceptibility to scams in community-dwelling older adults

Duke Han, S., Boyle, P. A., Yu, L., Arfanakis, K., James, B. D., Fleischman, D. A., & Bennett, D. A. (2016) · Brain Imaging and Behavior

Elder Abuse and NeglectDementia and Cognitive Impairment Research

Cited by 42

Trends in postmortem neurodegenerative and cerebrovascular neuropathologies over 25 years

Grodstein, F., Leurgans, S. E., Capuano, A. W., Schneider, J. A., & Bennett, D. A. (2023) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 41

Brain autopsies of critically ill COVID-19 patients demonstrate heterogeneous profile of acute vascular injury, inflammation and age-linked chronic brain diseases

Agrawal, S., Farfel, J. M., Arfanakis, K., Al-Harthi, L., Shull, T., Teppen, T. L., Evia, A. M., Patel, M. B., Ely, E. W., Leurgans, S. E., et al. (2022) · Acta Neuropathologica Communications

Long-Term Effects of COVID-19Infectious Encephalopathies and Encephalitis

Cited by 40

A cortical immune network map identifies a subset of human microglia involved in Tau pathology

Patrick, E., Olah, M., Taga, M., Klein, H.-U., Xu, J., White, C. C., Felsky, D., Gaiteri, C., Chibnik, L. B., Mostafavi, S., et al. (2017) · Translational Psychiatry

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 39

APOE genotype determines cell-type-specific pathological landscape of Alzheimer’s disease

Li, Z., Martens, Y. A., Ren, Y., Jin, Y., Sekiya, H., Doss, S. V., Kouri, N., Castanedes-Casey, M., Christensen, T. A., Miller Nevalainen, L. B., et al. (2025) · Neuron

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 39

Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

Sekiya, M., Wang, M., Fujisaki, N., Sakakibara, Y., Quan, X., Ehrlich, M. E., De Jager, P. L., Bennett, D. A., Schadt, E. E., Gandy, S., et al. (2018) · Genome Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 38

Cell-subtype specific effects of genetic variation in the aging and Alzheimer cortex

Fujita, M., Gao, Z., Zeng, L., McCabe, C., White, C. C., Ng, B., Green, G. S., Rozenblatt-Rosen, O., Phillips, D., Amir-Zilberstein, L., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Genetic Associations and EpidemiologySingle-cell and spatial transcriptomics

Cited by 36

Cognitive decline after elective and nonelective hospitalizations in older adults

James, B. D., Wilson, R. S., Capuano, A. W., Boyle, P. A., Shah, R. C., Lamar, M., Ely, E. W., Bennett, D. A., & Schneider, J. A. (2019) · Neurology

Dementia and Cognitive Impairment ResearchIntensive Care Unit Cognitive Disorders

Cited by 36

Multi-omic integration via similarity network fusion to detect molecular subtypes of ageing

Yang, M., Matan-Lithwick, S., Wang, Y., De Jager, P. L., Bennett, D. A., & Felsky, D. (2023) · Brain Communications

Bioinformatics and Genomic NetworksDementia and Cognitive Impairment Research

Cited by 35

Poor pulmonary function is associated with mild cognitive impairment, its progression to dementia, and brain pathologies: A community‐based cohort study

Wang, J., Dove, A., Song, R., Qi, X., Ma, J., Bennett, D. A., & Xu, W. (2022) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

Cited by 34

Cerebral Infarctions and the Relationship of Depression Symptoms to Level of Cognitive Functioning in Older Persons

Bennett, D. A., Wilson, R. S., Schneider, J. A., Bienias, J. L., & Arnold, S. E. (2004) · The American Journal of Geriatric Psychiatry

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

Cited by 33

Blood pressure variability, dementia, and role of antihypertensive medications in older adults

Mahinrad, S., Bennett, D. A., Sorond, F. A., & Gorelick, P. B. (2023) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchBlood Pressure and Hypertension Studies

Cited by 32

A new role for matrix metalloproteinase-3 in the NGF metabolic pathway: Proteolysis of mature NGF and sex-specific differences in the continuum of Alzheimer's pathology

Pentz, R., Iulita, M. F., Mikutra-Cencora, M., Ducatenzeiler, A., Bennett, D. A., & Cuello, A. C. (2021) · Neurobiology of Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 31

A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies

Patrick, E., Olah, M., Taga, M., Klein, H.-U., Xu, J., White, C. C., Felsky, D., Agrawal, S., Gaiteri, C., Chibnik, L. B., et al. (2021) · Translational Psychiatry

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 31

Bridging the gap: Multi‐omics profiling of brain tissue in Alzheimer's disease and older controls in multi‐ethnic populations

Reddy, J. S., Heath, L., Linden, A. V., Allen, M., Lopes, K. D. P., Seifar, F., Wang, E., Ma, Y., Poehlman, W. L., Quicksall, Z. S., et al. (2024) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 29

A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores

Kang, M., Ang, T. F. A., Devine, S. A., Sherva, R., Mukherjee, S., Trittschuh, E. H., Gibbons, L. E., Scollard, P., Lee, M., Choi, S.-E., et al. (2023) · Molecular Neurodegeneration

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 29