Bennett, David A.

Shared mechanisms across the major psychiatric and neurodegenerative diseases

Wingo, T. S., Liu, Y., Gerasimov, E. S., Vattathil, S. M., Wynne, M. E., Liu, J., Lori, A., Faundez, V., Bennett, D. A., Seyfried, N. T., et al. (2022) · Nature Communications

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 190

Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer’s disease

Zalocusky, K. A., Najm, R., Taubes, A. L., Hao, Y., Yoon, S. Y., Koutsodendris, N., Nelson, M. R., Rao, A., Bennett, D. A., Bant, J., et al. (2021) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 189

Purpose in life is associated with a reduced risk of incident disability among community-dwelling older persons

Boyle, P. A., Buchman, A. S., & Bennett, D. A. (2010) · The American Journal of Geriatric Psychiatry

Aging, Health, and DisabilityAging and Gerontology Research

Cited by 185

Elevated DNA methylation across a 48‐kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

Smith, R. G., Hannon, E., De Jager, P. L., Chibnik, L., Lott, S. J., Condliffe, D., Smith, A. R., Haroutunian, V., Troakes, C., Al‐Sarraj, S., et al. (2018) · Alzheimer's & Dementia

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 184

Personality and Mortality in Old Age

Wilson, R. S., Mendes de Leon, C. F., Bienias, J. L., Evans, D. A., & Bennett, D. A. (2004) · The Journals of Gerontology: Series B

Personality Traits and PsychologyAging and Gerontology Research

Cited by 182

Genome-wide association study of the rate of cognitive decline in Alzheimer’s disease

Sherva, R., Tripodis, Y., Bennett, D. A., Chibnik, L. B., Crane, P. K., de Jager, P. L., Farrer, L. A., Saykin, A. J., Shulman, J. M., Naj, A., et al. (2014) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 180

Life Space and Risk of Alzheimer Disease, Mild Cognitive Impairment, and Cognitive Decline in Old Age

James, B. D., Boyle, P. A., Buchman, A. S., Barnes, L. L., & Bennett, D. A. (2011) · The American Journal of Geriatric Psychiatry

Dementia and Cognitive Impairment ResearchAging, Health, and Disability

Cited by 177

A second X chromosome contributes to resilience in a mouse model of Alzheimer’s disease

Davis, E. J., Broestl, L., Abdulai-Saiku, S., Worden, K., Bonham, L. W., Miñones-Moyano, E., Moreno, A. J., Wang, D., Chang, K., Williams, G., et al. (2020) · Science Translational Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 176

Integrative metabolomics‐genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease

Horgusluoglu, E., Neff, R., Song, W., Wang, M., Wang, Q., Arnold, M., Krumsiek, J., Galindo‐Prieto, B., Ming, C., Nho, K., et al. (2022) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 175

Gender, cognitive decline, and risk of AD in older persons

Barnes, L. L., Wilson, R. S., Schneider, J. A., Bienias, J. L., Evans, D. A., & Bennett, D. A. (2003) · Neurology

Dementia and Cognitive Impairment ResearchMenopause: Health Impacts and Treatments

Cited by 173

Association of Mediterranean-DASH intervention for neurodegenerative delay and mediterranean diets with Alzheimer disease pathology

Agarwal, P., Leurgans, S. E., Agrawal, S., Aggarwal, N. T., Cherian, L. J., James, B. D., Dhana, K., Barnes, L. L., Bennett, D. A., & Schneider, J. A. (2023) · Neurology

Dementia and Cognitive Impairment ResearchNutritional Studies and Diet

Cited by 170

Neuropathological correlates and genetic architecture of microglial activation in elderly human brain

Felsky, D., Roostaei, T., Nho, K., Risacher, S. L., Bradshaw, E. M., Petyuk, V., Schneider, J. A., Saykin, A., Bennett, D. A., & De Jager, P. L. (2019) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 169

Genetics of the human microglia regulome refines Alzheimer’s disease risk loci

Kosoy, R., Fullard, J. F., Zeng, B., Bendl, J., Dong, P., Rahman, S., Kleopoulos, S. P., Shao, Z., Girdhar, K., Humphrey, J., et al. (2022) · Nature Genetics

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 168

Clinical-pathologic study of depressive symptoms and cognitive decline in old age

Wilson, R. S., Capuano, A. W., Boyle, P. A., Hoganson, G. M., Hizel, L. P., Shah, R. C., Nag, S., Schneider, J. A., Arnold, S. E., & Bennett, D. A. (2014) · Neurology

Dementia and Cognitive Impairment ResearchCancer-related cognitive impairment studies

Cited by 165

CD33 modulates TREM2: convergence of Alzheimer loci

Chan, G., White, C. C., Winn, P. A., Cimpean, M., Replogle, J. M., Glick, L. R., Cuerdon, N. E., Ryan, K. J., Johnson, K. A., Schneider, J. A., et al. (2015) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 162

Shared proteomic effects of cerebral atherosclerosis and Alzheimer’s disease on the human brain

Wingo, A. P., Fan, W., Duong, D. M., Gerasimov, E. S., Dammer, E. B., Liu, Y., Harerimana, N. V., White, B., Thambisetty, M., Troncoso, J. C., et al. (2020) · Nature Neuroscience

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 161

Virological and immunological characteristics of human cytomegalovirus infection associated with Alzheimer disease

Lurain, N. S., Hanson, B. A., Martinson, J., Leurgans, S. E., Landay, A. L., Bennett, D. A., & Schneider, J. A. (2013) · The Journal of Infectious Diseases

Cytomegalovirus and herpesvirus researchAlzheimer's disease research and treatments

Cited by 159

Change in risk of Alzheimer disease over time

Hebert, L. E., Bienias, J. L., Aggarwal, N. T., Wilson, R. S., Bennett, D. A., Shah, R. C., & Evans, D. A. (2010) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 158

Abnormal brain cholesterol homeostasis in Alzheimer’s disease-a targeted metabolomic and transcriptomic study

Varma, V. R., Büşra Lüleci, H., Oommen, A. M., Varma, S., Blackshear, C. T., Griswold, M. E., An, Y., Roberts, J. A., O’Brien, R., Pletnikova, O., et al. (2021) · npj Aging and Mechanisms of Disease

Alzheimer's disease research and treatmentsCholesterol and Lipid Metabolism

Cited by 153

Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors

Lagomarsino, V. N., Pearse, R. V., Liu, L., Hsieh, Y.-C., Fernandez, M. A., Vinton, E. A., Paull, D., Felsky, D., Tasaki, S., Gaiteri, C., et al. (2021) · Neuron

Alzheimer's disease research and treatmentsPluripotent Stem Cells Research

Cited by 151

Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer’s disease

Mahoney, E. R., Dumitrescu, L., Moore, A. M., Cambronero, F. E., De Jager, P. L., Koran, M. E. I., Petyuk, V. A., Robinson, R. A. S., Goyal, S., Schneider, J. A., et al. (2021) · Molecular Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 150

CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer’s disease susceptibility

Raj, T., Ryan, K. J., Replogle, J. M., Chibnik, L. B., Rosenkrantz, L., Tang, A., Rothamel, K., Stranger, B. E., Bennett, D. A., Evans, D. A., et al. (2014) · Human Molecular Genetics

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 144

Multi-cellular communities are perturbed in the aging human brain and Alzheimer’s disease

Cain, A., Taga, M., McCabe, C., Green, G., Hekselman, I., White, C. C., Lee, D. I., Gaur, P., Rozenblatt-Rosen, O., Zhang, F., et al. (2020) · Nature Neuroscience

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 143

Multicellular communities are perturbed in the aging human brain and Alzheimer’s disease

Cain, A., Taga, M., McCabe, C., Green, G. S., Hekselman, I., White, C. C., Lee, D. I., Gaur, P., Rozenblatt-Rosen, O., Zhang, F., et al. (2023) · Nature Neuroscience

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 142