Lefer, David J.

Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver

Duranski, M. R., Greer, J. J. M., Dejam, A., Jaganmohan, S., Hogg, N., Langston, W., Patel, R. P., Yet, S.-F., Wang, X., Kevil, C. G., et al. (2005) · Journal of Clinical Investigation

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Nitrate and nitrite in biology, nutrition and therapeutics

Lundberg, J. O., Gladwin, M. T., Ahluwalia, A., Benjamin, N., Bryan, N. S., Butler, A., Cabrales, P., Fago, A., Feelisch, M., Ford, P. C., et al. (2009) · Nature Chemical Biology

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Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

Shiva, S., Sack, M. N., Greer, J. J., Duranski, M., Ringwood, L. A., Burwell, L., Wang, X., MacArthur, P. H., Shoja, A., Raghavachari, N., et al. (2007) · The Journal of Experimental Medicine

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Guidelines for experimental models of myocardial ischemia and infarction

Lindsey, M. L., Bolli, R., Canty, J. M., Du, X.-J., Frangogiannis, N. G., Frantz, S., Gourdie, R. G., Holmes, J. W., Jones, S. P., Kloner, R. A., et al. (2018) · American Journal of Physiology-Heart and Circulatory Physiology

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Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling

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Choline Diet and Its Gut Microbe–Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload–Induced Heart Failure

Organ, C. L., Otsuka, H., Bhushan, S., Wang, Z., Bradley, J., Trivedi, R., Polhemus, D. J., Tang, W. H. W., Wu, Y., Hazen, S. L., et al. (2016) · Circulation: Heart Failure

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Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury

Bryan, N. S., Calvert, J. W., Elrod, J. W., Gundewar, S., Ji, S. Y., & Lefer, D. J. (2007) · Proceedings of the National Academy of Sciences

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A Proliferative Burst during Preadolescence Establishes the Final Cardiomyocyte Number

Naqvi, N., Li, M., Calvert, J. W., Tejada, T., Lambert, J. P., Wu, J., Kesteven, S. H., Holman, S. R., Matsuda, T., Lovelock, J. D., et al. (2014) · Cell

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Modulation of leukocyte–endothelial interactions by reactive metabolites of oxygen and nitrogen: relevance to ischemic heart disease

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Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging: Sodium nitrite and vascular dysfunction with aging

Sindler, A. L., Fleenor, B. S., Calvert, J. W., Marshall, K. D., Zigler, M. L., Lefer, D. J., & Seals, D. R. (2011) · Aging Cell

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Endothelial nitric oxide synthase overexpression attenuates myocardial reperfusion injury

Jones, S. P., Greer, J. J. M., Kakkar, A. K., Ware, P. D., Turnage, R. H., Hicks, M., van Haperen, R., de Crom, R., Kawashima, S., Yokoyama, M., et al. (2004) · American Journal of Physiology-Heart and Circulatory Physiology

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Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis

Kumar, D., Branch, B. G., Pattillo, C. B., Hood, J., Thoma, S., Simpson, S., Illum, S., Arora, N., Chidlow, J. H., Langston, W., et al. (2008) · Proceedings of the National Academy of Sciences

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Dietary nitrite restores NO homeostasis and is cardioprotective in endothelial nitric oxide synthase-deficient mice

Bryan, N. S., Calvert, J. W., Gundewar, S., & Lefer, D. J. (2008) · Free Radical Biology and Medicine

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Nitric oxide promotes distant organ protection: evidence for an endocrine role of nitric oxide

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Myocardial infarction and heart failure in the db/db diabetic mouse

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Dietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop

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Reperfusion injury is not affected by blockade of P-selectin in the diabetic mouse heart

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Increased disease activity in eNOS-deficient mice in experimental colitis

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Nitrite therapy improves left ventricular function during heart failure via restoration of nitric oxide-mediated cytoprotective signaling

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Single-Dose Pharmacokinetics of Different Oral Sodium Nitrite Formulations in Diabetes Patients

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