Fuchs, Elaine

Asymmetric cell divisions promote Notch-dependent epidermal differentiation

Williams, S. E., Beronja, S., Pasolli, H. A., & Fuchs, E. (2011) · Nature

Developmental Biology and Gene RegulationMicrotubule and mitosis dynamics

Cited by 406

The tortoise and the hair: slow-cycling cells in the stem cell race

Fuchs, E. (2009) · Cell

Developmental Biology and Gene RegulationHematopoietic Stem Cell Transplantation

Cited by 371

EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair

Ezhkova, E., Lien, W.-H., Stokes, N., Pasolli, H. A., Silva, J. M., & Fuchs, E. (2011) · Genes & Development

Hair Growth and DisordersEpigenetics and DNA Methylation

Cited by 357

Actin Cable Dynamics and Rho/Rock Orchestrate a Polarized Cytoskeletal Architecture in the Early Steps of Assembling a Stratified Epithelium

Vaezi, A., Bauer, C., Vasioukhin, V., & Fuchs, E. (2002) · Developmental Cell

Skin and Cellular Biology ResearchCellular Mechanics and Interactions

Cited by 349

Tissue Stem Cells: Architects of Their Niches

Fuchs, E., & Blau, H. M. (2020) · Cell Stem Cell

Mesenchymal stem cell researchHair Growth and Disorders

Cited by 332

Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair

Lu, C. P., Polak, L., Rocha, A. S., Pasolli, H. A., Chen, S.-C., Sharma, N., Blanpain, C., & Fuchs, E. (2012) · Cell

Hair Growth and DisordersMesenchymal stem cell research

Cited by 301

Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells

Miao, Y., Yang, H., Levorse, J., Yuan, S., Polak, L., Sribour, M., Singh, B., Rosenblum, M. D., & Fuchs, E. (2019) · Cell

Cancer Immunotherapy and BiomarkersCancer Cells and Metastasis

Cited by 299

Interferon-γ links ultraviolet radiation to melanomagenesis in mice

Zaidi, M. R., Davis, S., Noonan, F. P., Graff-Cherry, C., Hawley, T. S., Walker, R. L., Feigenbaum, L., Fuchs, E., Lyakh, L., Young, H. A., et al. (2011) · Nature

Cutaneous Melanoma Detection and ManagementMelanoma and MAPK Pathways

Cited by 293

Impaired Epidermal to Dendritic T Cell Signaling Slows Wound Repair in Aged Skin

Keyes, B. E., Liu, S., Asare, A., Naik, S., Levorse, J., Polak, L., Lu, C. P., Nikolova, M., Pasolli, H. A., & Fuchs, E. (2016) · Cell

Wound Healing and TreatmentsCytokine Signaling Pathways and Interactions

Cited by 266

UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling

Moore, C., Cevikbas, F., Pasolli, H. A., Chen, Y., Kong, W., Kempkes, C., Parekh, P., Lee, S. H., Kontchou, N.-A., Yeh, I., et al. (2013) · Proceedings of the National Academy of Sciences

Ion Channels and ReceptorsPain Mechanisms and Treatments

Cited by 259

DGCR8-dependent microRNA biogenesis is essential for skin development

Yi, R., Pasolli, H. A., Landthaler, M., Hafner, M., Ojo, T., Sheridan, R., Sander, C., O'Carroll, D., Stoffel, M., Tuschl, T., et al. (2009) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationDevelopmental Biology and Gene Regulation

Cited by 232

More than one way to skin . . .

Fuchs, E., & Horsley, V. (2008) · Genes & Development

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 224

Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage

Lien, W.-H., Guo, X., Polak, L., Lawton, L. N., Young, R. A., Zheng, D., & Fuchs, E. (2011) · Cell Stem Cell

Hair Growth and DisordersEpigenetics and DNA Methylation

Cited by 199

Conditional targeting of E-cadherin in skin: Insights into hyperproliferative and degenerative responses

Tinkle, C. L., Lechler, T., Pasolli, H. A., & Fuchs, E. (2004) · Proceedings of the National Academy of Sciences

Skin and Cellular Biology ResearchCell Adhesion Molecules Research

Cited by 193

The aging skin microenvironment dictates stem cell behavior

Ge, Y., Miao, Y., Gur-Cohen, S., Gomez, N., Yang, H., Nikolova, M., Polak, L., Hu, Y., Verma, A., Elemento, O., et al. (2020) · Proceedings of the National Academy of Sciences

Hair Growth and DisordersHematopoietic Stem Cell Transplantation

Cited by 190

β1-Integrins Are Required for Hippocampal AMPA Receptor-Dependent Synaptic Transmission, Synaptic Plasticity, and Working Memory

Chan, C.-S., Weeber, E. J., Zong, L., Fuchs, E., Sweatt, J. D., & Davis, R. L. (2006) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchCell Adhesion Molecules Research

Cited by 165

Spatiotemporal antagonism in mesenchymal-epithelial signaling in sweat versus hair fate decision

Lu, C. P., Polak, L., Keyes, B. E., & Fuchs, E. (2016) · Science

Hair Growth and DisordersDevelopmental Biology and Gene Regulation

Cited by 149

Universal recording of immune cell interactions in vivo

Nakandakari-Higa, S., Walker, S., Canesso, M. C. C., van der Heide, V., Chudnovskiy, A., Kim, D.-Y., Jacobsen, J. T., Parsa, R., Bilanovic, J., Parigi, S. M., et al. (2024) · Nature

T-cell and B-cell ImmunologyBiotin and Related Studies

Cited by 136

Universal recording of cell-cell contacts in vivo for interaction-based transcriptomics

Nakandakari-Higa, S., Canesso, M. C. C., Walker, S., Chudnovskiy, A., Jacobsen, J. T., Bilanovic, J., Parigi, S. M., Fiedorczuk, K., Fuchs, E., Bilate, A. M., et al. (2023) · Nature

T-cell and B-cell ImmunologyBiotin and Related Studies

Cited by 134

Extracellular serine controls epidermal stem cell fate and tumour initiation

Baksh, S. C., Todorova, P. K., Gur-Cohen, S., Hurwitz, B., Ge, Y., Novak, J. S. S., Tierney, M. T., dela Cruz-Racelis, J., Fuchs, E., & Finley, L. W. S. (2020) · Nature Cell Biology

Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis

Cited by 128

A tissue injury sensing and repair pathway distinct from host pathogen defense

Liu, S., Hur, Y. H., Cai, X., Cong, Q., Yang, Y., Xu, C., Bilate, A. M., Gonzales, K. A. U., Parigi, S. M., Cowley, C. J., et al. (2023) · Cell

Wound Healing and TreatmentsCytokine Signaling Pathways and Interactions

Cited by 108

Cyfip1 is a putative invasion suppressor in epithelial cancers

Silva, J. M., Ezhkova, E., Silva, J., Heart, S., Castillo, M., Campos, Y., Castro, V., Bonilla, F., Cordon-Cardo, C., Muthuswamy, S. K., et al. (2009) · Cell

Mechanisms of cancer metastasisCellular Mechanics and Interactions

Cited by 87

BMP signaling: at the gate between activated melanocyte stem cells and differentiation

Infarinato, N. R., Stewart, K. S., Yang, Y., Gomez, N. C., Pasolli, H. A., Hidalgo, L., Polak, L., Carroll, T. S., & Fuchs, E. (2020) · Genes & Development

melanin and skin pigmentationHair Growth and Disorders

Cited by 62