Fuchs, Elaine

Defining trained immunity and its role in health and disease

Netea, M. G., Domínguez-Andrés, J., Barreiro, L. B., Chavakis, T., Divangahi, M., Fuchs, E., Joosten, L. A. B., van der Meer, J. W. M., Mhlanga, M. M., Mulder, W. J. M., et al. (2020) · Nature Reviews Immunology

Immune responses and vaccinationsImmune Response and Inflammation

Cited by 2,690

Defining the Epithelial Stem Cell Niche in Skin

Tumbar, T., Guasch, G., Greco, V., Blanpain, C., Lowry, W. E., Rendl, M., & Fuchs, E. (2004) · Science

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 2,031

Self-Renewal, Multipotency, and the Existence of Two Cell Populations within an Epithelial Stem Cell Niche

Blanpain, C., Lowry, W. E., Geoghegan, A., Polak, L., & Fuchs, E. (2004) · Cell

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 1,428

Epidermal homeostasis: a balancing act of stem cells in the skin

Blanpain, C., & Fuchs, E. (2009) · Nature Reviews Molecular Cell Biology

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 1,270

Directed Actin Polymerization Is the Driving Force for Epithelial Cell–Cell Adhesion

Vasioukhin, V., Bauer, C., Yin, M., & Fuchs, E. (2000) · Cell

Cellular Mechanics and InteractionsCell Adhesion Molecules Research

Cited by 1,205

De Novo Hair Follicle Morphogenesis and Hair Tumors in Mice Expressing a Truncated β-Catenin in Skin

Gat, U., DasGupta, R., Degenstein, L., & Fuchs, E. (1998) · Cell

Hair Growth and DisordersWnt/β-catenin signaling in development and cancer

Cited by 1,089

Asymmetric cell divisions promote stratification and differentiation of mammalian skin

Lechler, T., & Fuchs, E. (2005) · Nature

Skin and Cellular Biology ResearchHair Growth and Disorders

Cited by 998

Scratching the surface of skin development

Fuchs, E. (2007) · Nature

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 930

A Two-Step Mechanism for Stem Cell Activation during Hair Regeneration

Greco, V., Chen, T., Rendl, M., Schober, M., Pasolli, H. A., Stokes, N., dela Cruz-Racelis, J., & Fuchs, E. (2009) · Cell Stem Cell

Hair Growth and Disordersdental development and anomalies

Cited by 800

A skin microRNA promotes differentiation by repressing ‘stemness’

Yi, R., Poy, M. N., Stoffel, M., & Fuchs, E. (2008) · Nature

MicroRNA in disease regulationHair Growth and Disorders

Cited by 790

Getting under the skin of epidermal morphogenesis

Fuchs, E., & Raghavan, S. (2002) · Nature Reviews Genetics

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 753

Regulation of terminal differentiation of cultured human keratinocytes by vitamin A

Fuchs, E., & Green, H. (1981) · Cell

Skin and Cellular Biology ResearchRetinoids in leukemia and cellular processes

Cited by 750

Inflammatory memory sensitizes skin epithelial stem cells to tissue damage

Naik, S., Larsen, S. B., Gomez, N. C., Alaverdyan, K., Sendoel, A., Yuan, S., Polak, L., Kulukian, A., Chai, S., & Fuchs, E. (2017) · Nature

Inflammasome and immune disordersHair Growth and Disorders

Cited by 745

A common human skin tumour is caused by activating mutations in β-catenin

Chan, E., Gat, U., McNiff, J. M., & Fuchs, E. (1999) · Nature Genetics

Wnt/β-catenin signaling in development and cancerCancer and Skin Lesions

Cited by 612

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

Kaneko, H., Dridi, S., Tarallo, V., Gelfand, B. D., Fowler, B. J., Cho, W. G., Kleinman, M. E., Ponicsan, S. L., Hauswirth, W. W., Chiodo, V. A., et al. (2011) · Nature

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 601

Plasticity of epithelial stem cells in tissue regeneration

Blanpain, C., & Fuchs, E. (2014) · Science

Mesenchymal stem cell researchCancer Cells and Metastasis

Cited by 589

Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs

Yi, R., O'Carroll, D., Pasolli, H. A., Zhang, Z., Dietrich, F. S., Tarakhovsky, A., & Fuchs, E. (2006) · Nature Genetics

Hair Growth and DisordersMicroRNA in disease regulation

Cited by 555

Hair follicle stem cells are specified and function in early skin morphogenesis

Nowak, J. A., Polak, L., Pasolli, H. A., & Fuchs, E. (2008) · Cell Stem Cell

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 554

TGF-β Promotes Heterogeneity and Drug Resistance in Squamous Cell Carcinoma

Oshimori, N., Oristian, D., & Fuchs, E. (2015) · Cell

TGF-β signaling in diseasesCancer Cells and Metastasis

Cited by 471

Hyperproliferation and Defects in Epithelial Polarity upon Conditional Ablation of α-Catenin in Skin

Vasioukhin, V., Bauer, C., Degenstein, L., Wise, B., & Fuchs, E. (2001) · Cell

Wnt/β-catenin signaling in development and cancerSkin and Cellular Biology Research

Cited by 435

Blimp1 Defines a Progenitor Population that Governs Cellular Input to the Sebaceous Gland

Horsley, V., O'Carroll, D., Tooze, R., Ohinata, Y., Saitou, M., Obukhanych, T., Nussenzweig, M., Tarakhovsky, A., & Fuchs, E. (2006) · Cell

Hair Growth and DisordersGenetic and rare skin diseases.

Cited by 426

NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells

Horsley, V., Aliprantis, A. O., Polak, L., Glimcher, L. H., & Fuchs, E. (2008) · Cell

Hair Growth and DisordersSignaling Pathways in Disease

Cited by 424

Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin

Zhang, H., Pasolli, H. A., & Fuchs, E. (2011) · Proceedings of the National Academy of Sciences

Hippo pathway signaling and YAP/TAZHair Growth and Disorders

Cited by 419

Skin and Its Regenerative Powers: An Alliance between Stem Cells and Their Niche

Gonzales, K. A. U., & Fuchs, E. (2017) · Developmental Cell

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 414