Sancar, Aziz

Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints

Sancar, A., Lindsey-Boltz, L. A., Ünsal-Kaçmaz, K., & Linn, S. (2004) · Annual Review of Biochemistry

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 3,317

DNA excision repair

Sancar, A. (1996) · Annual Review of Biochemistry

DNA Repair MechanismsGenetic factors in colorectal cancer

Cited by 1,131

Differential regulation of mammalian Period genes and circadian rhythmicity by cryptochromes 1 and 2

Vitaterna, M. H., Selby, C. P., Todo, T., Niwa, H., Thompson, C., Fruechte, E. M., Hitomi, K., Thresher, R. J., Ishikawa, T., Miyazaki, J., et al. (1999) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninLight effects on plants

Cited by 690

Reconstitution of Human DNA Repair Excision Nuclease in a Highly Defined System

Mu, D., Park, C.-H., Matsunaga, T., Hsu, D. S., Reardon, J. T., & Sancar, A. (1995) · Journal of Biological Chemistry

DNA Repair MechanismsNuclear Structure and Function

Cited by 476

In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients

Reardon, J. T., Bessho, T., Kung, H. C., Bolton, P. H., & Sancar, A. (1997) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsCarcinogens and Genotoxicity Assessment

Cited by 366

Nucleotide Excision Repair

Reardon, J. T., & Sancar, A. (2005) · Progress in Nucleic Acid Research and Molecular Biology

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 350

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

Bermudez, V. P., Lindsey-Boltz, L. A., Cesare, A. J., Maniwa, Y., Griffith, J. D., Hurwitz, J., & Sancar, A. (2003) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 324

Coupling of Human Circadian and Cell Cycles by the Timeless Protein

Ünsal-Kaçmaz, K., Mullen, T. E., Kaufmann, W. K., & Sancar, A. (2005) · Molecular and Cellular Biology

Circadian rhythm and melatoninDNA Repair Mechanisms

Cited by 310

Putative Human Blue-Light Photoreceptors hCRY1 and hCRY2 Are Flavoproteins

Hsu, D. S., Zhao, X., Zhao, S., Kazantsev, A., Wang, R.-P., Todo, T., Wei, Y.-F., & Sancar, A. (1996) · Biochemistry

Light effects on plantsCircadian rhythm and melatonin

Cited by 291

Human Transcription-Repair Coupling Factor CSB/ERCC6 Is a DNA-stimulated ATPase but Is Not a Helicase and Does Not Disrupt the Ternary Transcription Complex of Stalled RNA Polymerase II

Selby, C. P., & Sancar, A. (1997) · Journal of Biological Chemistry

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 267

Direct observation of thymine dimer repair in DNA by photolyase

Kao, Y.-T., Saxena, C., Wang, L., Sancar, A., & Zhong, D. (2005) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsPhotochemistry and Electron Transfer Studies

Cited by 259

Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase

Kang, T.-H., Lindsey-Boltz, L. A., Reardon, J. T., & Sancar, A. (2010) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninDNA Repair Mechanisms

Cited by 250

The Human Tim/Tipin Complex Coordinates an Intra-S Checkpoint Response to UV That Slows Replication Fork Displacement

Ünsal-Kaçmaz, K., Chastain, P. D., Qu, P.-P., Minoo, P., Cordeiro-Stone, M., Sancar, A., & Kaufmann, W. K. (2007) · Molecular and Cellular Biology

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 240

DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair

Wakasugi, M., Kawashima, A., Morioka, H., Linn, S., Sancar, A., Mori, T., Nikaido, O., & Matsunaga, T. (2002) · Journal of Biological Chemistry

DNA Repair MechanismsNuclear Structure and Function

Cited by 227

Escherichia coli mfd mutant deficient in "mutation frequency decline" lacks strand-specific repair: in vitro complementation with purified coupling factor.

Selby, C. P., Witkin, E. M., & Sancar, A. (1991) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsBacterial Genetics and Biotechnology

Cited by 215

Structure and Function of Photolyase and in Vivo Enzymology: 50th Anniversary

Sancar, A. (2008) · Journal of Biological Chemistry

DNA Repair MechanismsEnzyme Structure and Function

Cited by 204

Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins

Park, C. H., & Sancar, A. (1994) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsGenetic factors in colorectal cancer

Cited by 189

Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice.

Selby, C. P., Thompson, C., Schmitz, T. M., Van Gelder, R. N., & Sancar, A. (2000) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninRetinal Development and Disorders

Cited by 184

Identification of the second chromophore of Escherichia coli and yeast DNA photolyases as 5,10-methenyltetrahydrofolate.

Johnson, J. L., Hamm-Alvarez, S., Payne, G., Sancar, G. B., Rajagopalan, K. V., & Sancar, A. (1988) · Proceedings of the National Academy of Sciences

Folate and B Vitamins ResearchPorphyrin Metabolism and Disorders

Cited by 179

Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease

Reardon, J. T., & Sancar, A. (2003) · Genes & Development

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 179

Preferential binding of ATR protein to UV-damaged DNA

Ünsal-Kaçmaz, K., Makhov, A. M., Griffith, J. D., & Sancar, A. (2002) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 176

Circadian Clock, Cancer, and Chemotherapy

Sancar, A., Lindsey-Boltz, L. A., Gaddameedhi, S., Selby, C. P., Ye, R., Chiou, Y.-Y., Kemp, M. G., Hu, J., Lee, J. H., & Ozturk, N. (2015) · Biochemistry

Circadian rhythm and melatoninCancer-related Molecular Pathways

Cited by 170

Overproduction, Purification, and Characterization of the XPC Subunit of the Human DNA Repair Excision Nuclease

Reardon, J. T., Mu, D., & Sancar, A. (1996) · Journal of Biological Chemistry

DNA Repair MechanismsNuclear Structure and Function

Cited by 161

Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21

Pan, Z.-Q., Reardon, J. T., Li, L., Flores-Rozas, H., Legerski, R., Sancar, A., & Hurwitz, J. (1995) · Journal of Biological Chemistry

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 151