The Human Tim/Tipin Complex Coordinates an Intra-S Checkpoint Response to UV That Slows Replication Fork Displacement

Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints

Sancar, A., Lindsey-Boltz, L. A., Ünsal-Kaçmaz, K., & Linn, S. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.073723 · Cited by 3,317 · see citing works

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η

Masutani, C., Kusumoto, R., Yamada, A., Dohmae, N., Yokoi, M., Yuasa, M., Araki, M., Iwai, S., Takio, K., & Hanaoka, F. (1999) · Nature · doi:10.1038/21447 · Cited by 1,292 · see citing works

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Falck, J., Mailand, N., Syljuåsen, R. G., Bartek, J., & Lukas, J. (2001) · Nature · doi:10.1038/35071124 · Cited by 1,085 · see citing works

Replicon Clusters Are Stable Units of Chromosome Structure: Evidence That Nuclear Organization Contributes to the Efficient Activation and Propagation of S Phase in Human Cells

Jackson, D., & Pombo, A. (1998) · Journal of Cell Biology · doi:10.1083/jcb.140.6.1285 · Cited by 881 · see citing works

Radiosensitivity in ataxia-telangiectasia: a new explanation.

Painter, R. B., & Young, B. R. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.12.7315 · Cited by 794 · see citing works

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint

Byun, T. S., Pacek, M., Yee, M.-C., Walter, J. C., & Cimprich, K. A. (2005) · Genes & Development · doi:10.1101/gad.1301205 · Cited by 767 · see citing works

The DNA replication checkpoint response stabilizes stalled replication forks

Lopes, M., Cotta‐Ramusino, C., Pellicioli, A., Liberi, G., Plevani, P., Muzi-Falconi, M., Newlon, C. S., & Foiani, M. (2001) · Nature · doi:10.1038/35087613 · Cited by 749 · see citing works

TopBP1 Activates the ATR-ATRIP Complex

Kumagai, A., Lee, J., Yoo, H. Y., & Dunphy, W. G. (2006) · Cell · doi:10.1016/j.cell.2005.12.041 · Cited by 743 · see citing works

<i>hRAD30</i> Mutations in the Variant Form of Xeroderma Pigmentosum

Johnson, R. E., Kondratick, C. M., Prakash, S., & Prakash, L. (1999) · Science · doi:10.1126/science.285.5425.263 · Cited by 732 · see citing works

Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint

Tercero, J. A., & Diffley, J. F. X. (2001) · Nature · doi:10.1038/35087607 · Cited by 667 · see citing works

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

Bekker‐Jensen, S., Lukas, C., Kitagawa, R., Melander, F., Kastan, M. B., Bártek, J., & Lukas, J. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200510130 · Cited by 621 · see citing works

The role of sunlight and DNA repair in melanoma and nonmelanoma skin cancer. The xeroderma pigmentosum paradigm

Kraemer, K. H. (1994) · Archives of Dermatology · doi:10.1001/archderm.130.8.1018 · Cited by 571 · see citing works

Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions

Lopes, M., Foiani, M., & Sogo, J. M. (2006) · Molecular Cell · doi:10.1016/j.molcel.2005.11.015 · Cited by 563 · see citing works

The DNA damage-dependent intra–S phase checkpoint is regulated by parallel pathways

Falck, J., Petrini, J. H. J., Williams, B. R., Lukas, J., & Bartek, J. (2002) · Nature Genetics · doi:10.1038/ng845 · Cited by 392 · see citing works

RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

He, Z., Henricksen, L. A., Wold, M. S., & Ingles, C. J. (1995) · Nature · doi:10.1038/374566a0 · Cited by 389 · see citing works

An ATR- and Cdc7-Dependent DNA Damage Checkpoint that Inhibits Initiation of DNA Replication

Costanzo, V., Shechter, D., Lupardus, P. J., Cimprich, K. A., Gottesman, M. E., & Gautier, J. (2003) · Molecular Cell · doi:10.1016/s1097-2765(02)00799-2 · Cited by 355 · see citing works

DNA damage and cell cycle checkpoints

Kaufmann, W. K., & Paules, R. S. (1996) · The FASEB Journal · doi:10.1096/fasebj.10.2.8641557 · Cited by 315 · see citing works

Cyclobutane Pyrimidine Dimers Are Responsible for the Vast Majority of Mutations Induced by UVB Irradiation in Mammalian Cells

You, Y.-H., Lee, D.-H., Yoon, J.-H., Nakajima, S., Yasui, A., & Pfeifer, G. P. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m107696200 · Cited by 314 · see citing works

Coupling of Human Circadian and Cell Cycles by the Timeless Protein

Ünsal-Kaçmaz, K., Mullen, T. E., Kaufmann, W. K., & Sancar, A. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.8.3109-3116.2005 · Cited by 310 · see citing works

Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication forkPreprint

Calzada, A., Hodgson, B., Kanemaki, M. T., Bueno, A., & Labib, K. P. M. (2005) · Genes & Development · doi:10.1101/gad.337205 · Cited by 280 · see citing works

Mrc1 and Tof1 Promote Replication Fork Progression and Recovery Independently of Rad53

Tourrière, H., Versini, G., Cordón-Preciado, V., Alabert, C., & Pasero, P. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.07.028 · Cited by 265 · see citing works

Structural Basis for the Recognition of DNA Repair Proteins UNG2, XPA, and RAD52 by Replication Factor RPA

Mer, G., Bochkarev, A. V., Gupta, R., Bochkareva, E. S., Frappier, L., Ingles, C. J., Edwards, A. M., & Chazin, W. (2000) · Cell · doi:10.1016/s0092-8674(00)00136-7 · Cited by 254 · see citing works

An ATR- and Chk1-Dependent S Checkpoint Inhibits Replicon Initiation following UVC-Induced DNA Damage

Heffernan, T. P., Simpson, D. A., Frank, A. R., Heinloth, A. N., Paules, R. S., Cordeiro-Stone, M., & Kaufmann, W. K. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.24.8552-8561.2002 · Cited by 251 · see citing works

Human Claspin Is Required for Replication Checkpoint Control

Chini, C. C. S., & Chen, J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301136200 · Cited by 244 · see citing works

Identification of Protein Complexes Required for Efficient Sister Chromatid Cohesion

Mayer, M. L., Pot, I., Chang, M., Xu, H., Aneliunas, V., Kwok, T., Newitt, R., Aebersold, R. H., Boone, C. M., Brown, G. W., et al. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-08-0619 · Cited by 235 · see citing works

Visualization of Altered Replication Dynamics after DNA Damage in Human Cells

Merrick, C. J., Jackson, D. A., & Diffley, J. F. X. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400022200 · Cited by 228 · see citing works

Swi1 and Swi3 Are Components of a Replication Fork Protection Complex in Fission Yeast

Noguchi, E., Noguchi, C., McDonald, W. H., Yates, J. R., & Russell, P. R. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.19.8342-8355.2004 · Cited by 205 · see citing works

Claspin Operates Downstream of TopBP1 To Direct ATR Signaling towards Chk1 Activation

Liu, S., Bekker‐Jensen, S., Mailand, N., Lukas, C., Bártek, J., & Lukas, J. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00492-06 · Cited by 184 · see citing works

Chk1 Requirement for High Global Rates of Replication Fork Progression during Normal Vertebrate S Phase

Petermann, E., Maya‐Mendoza, A., Zachos, G., Gillespie, D. A., Jackson, D. A., & Caldecott, K. W. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.8.3319-3326.2006 · Cited by 183 · see citing works

Reconstitution of an ATM-Dependent Checkpoint that Inhibits Chromosomal DNA Replication following DNA Damage

Costanzo, V., Robertson, K. M.-P., Ying, C. Y., Kim, E., Avvedimento, E. V., Gottesman, M. E., Grieco, D., & Gautier, J. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00063-0 · Cited by 176 · see citing works

Requirement of RAD5 and MMS2 for Postreplication Repair of UV-Damaged DNA in Saccharomyces cerevisiae

Torres‐Ramos, C. A., Prakash, S., & Prakash, L. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.7.2419-2426.2002 · Cited by 170 · see citing works

Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function

Chou, D. M., & Elledge, S. J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0609251103 · Cited by 166 · see citing works

Swi1 Prevents Replication Fork Collapse and Controls Checkpoint Kinase Cds1

Noguchi, E., Noguchi, C., Du, L., & Russell, P. R. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.21.7861-7874.2003 · Cited by 163 · see citing works

Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation

Lin, S.-Y., Li, K., Stewart, G. S., & Elledge, S. J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0401847101 · Cited by 156 · see citing works

Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis

Haracska, L., Unk, I., Prakash, L., & Prakash, S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510924103 · Cited by 136 · see citing works

Mammalian TIMELESS and Tipin are Evolutionarily Conserved Replication Fork-associated Factors

Gotter, A. L., Suppa, C., & Emanuel, B. S. (2006) · Journal of Molecular Biology · doi:10.1016/j.jmb.2006.10.097 · Cited by 135 · see citing works

Uncoupling of Unwinding from DNA Synthesis Implies Regulation of MCM Helicase by Tof1/Mrc1/Csm3 Checkpoint Complex

Nedelcheva, M. N., Roguev, A., Dolapchiev, L. B., Shevchenko, A., Taskov, H. B., Shevchenko, A., Stewart, A. F., & Stoynov, S. (2005) · Journal of Molecular Biology · doi:10.1016/j.jmb.2005.01.041 · Cited by 135 · see citing works

The Tof1p–Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae

Mohanty, B. K., Bairwa, N. K., & Bastia, D. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506540103 · Cited by 134 · see citing works

Human Tim/Timeless-interacting Protein, Tipin, Is Required for Efficient Progression of S Phase and DNA Replication Checkpoint

Yoshizawa-Sugata, N., & Masai, H. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m605596200 · Cited by 127 · see citing works

Tof1p Regulates DNA Damage Responses During S Phase in Saccharomyces cerevisiae

Foss, E. J. (2001) · Genetics · doi:10.1093/genetics/157.2.567 · Cited by 126 · see citing works

Mechanisms of inhibition of DNA replication by ultraviolet light in normal human and xeroderma pigmentosum fibroblasts

Kaufmann, W. K., & Cleaver, J. E. (1981) · Journal of Molecular Biology · doi:10.1016/0022-2836(81)90297-7 · Cited by 121 · see citing works

DNA double labelling with IdUrd and CldUrd for spatial and temporal analysis of cell proliferation and DNA replication

Aten, J. A., Bakker, P. J. M., Stap, J., Boschman, G. A., & Veenhof, C. H. N. (1992) · The Histochemical Journal · doi:10.1007/bf01046839 · Cited by 118 · see citing works

Differential replication of a single, UV-induced lesion in the leading or lagging strand by a human cell extract: fork uncoupling or gap formation.

Svoboda, D. L., & Vos, J. M. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.26.11975 · Cited by 111 · see citing works

Mrc1 Is Required for Sister Chromatid Cohesion To Aid in Recombination Repair of Spontaneous Damage

Xu, H., Boone, C. M., & Klein, H. L. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.16.7082-7090.2004 · Cited by 108 · see citing works

The Role of DNA Polymerase η in Translesion Synthesis Past Platinum–DNA Adducts in Human Fibroblasts

Bassett, E., King, N. M., Bryant, M. F., Hector, S., Pendyala, L., Chaney, S. G., & Cordeiro‐Stone, M. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-1328 · Cited by 107 · see citing works

swi1 - and swi3 -dependent and independent replication fork arrest at the ribosomal DNA of Schizosaccharomyces pombe

Krings, G., & Bastia, D. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406037101 · Cited by 106 · see citing works

Analysis of DNA replication forks encountering a pyrimidine dimer in the template to the leading strand 1 1Edited by M. Yaniv

Cordeiro‐Stone, M., Makhov, A. M., Zaritskaya, L., & Griffith, J. D. (1999) · Journal of Molecular Biology · doi:10.1006/jmbi.1999.2847 · Cited by 102 · see citing works

The Chk1-mediated S-phase Checkpoint Targets Initiation Factor Cdc45 via a Cdc25A/Cdk2-independent Mechanism

Liu, P., Barkley, L. R., Day, T. A., Bi, X., Slater, D., Alexandrow, M. G., Nasheuer, H., & Vaziri, C. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602982200 · Cited by 97 · see citing works

Cell cycle control, DNA repair and initiation of carcinogenesis

Kaufmann, W. K., & Kaufman, D. G. (1993) · The FASEB Journal · doi:10.1096/fasebj.7.12.8375618 · Cited by 81 · see citing works

Cdc7-Dbf4 and the Human S Checkpoint Response to UVC

Heffernan, T. P., Ünsal-Kaçmaz, K., Heinloth, A. N., Simpson, D. A., Paules, R. S., Sancar, A., Cordeiro‐Stone, M., & Kaufmann, W. K. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m611292200 · Cited by 78 · see citing works

Spatial Distributions of Early and Late Replicating Chromatin in Interphase Chromosome Territories

Visser, A. E., Eils, R., Jauch, A. T., Little, G., Bakker, P. J. M., Cremer, T. J., & Aten, J. A. (1998) · Experimental Cell Research · doi:10.1006/excr.1998.4144 · Cited by 72 · see citing works

Critical Role for Mouse Hus1 in an S-Phase DNA Damage Cell Cycle Checkpoint

Weiss, R. S., Leder, P., & Vaziri, C. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.3.791-803.2003 · Cited by 70 · see citing works

Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences

Jiang, G., & Sancar, A. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.1.39-49.2006 · Cited by 70 · see citing works

Xeroderma Pigmentosum Complementation Group E Protein (XPE/DDB2): Purification of Various Complexes of XPE and Analyses of Their Damaged DNA Binding and Putative DNA Repair Properties

Kulaksiz-Erkmen, G., Reardon, J. T., & Sancar, A. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.22.9784-9792.2005 · Cited by 65 · see citing works

Tipin, a Novel Timeless-Interacting Protein, is Developmentally Co-expressed with Timeless and Disrupts its Self-association

Gotter, A. L. (2003) · Journal of Molecular Biology · doi:10.1016/s0022-2836(03)00633-8 · Cited by 64 · see citing works

Regulation of Cellular and SV40 Virus Origins of Replication by Chk1-dependent Intrinsic and UVC Radiation-induced Checkpoints

Miao, H., Seiler, J. A., & Burhans, W. C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m204264200 · Cited by 62 · see citing works

Hsk1-Dfp1/Him1, the Cdc7-Dbf4 Kinase in Schizosaccharomyces pombe, Associates with Swi1, a Component of the Replication Fork Protection Complex

Matsumoto, S., Ogino, K., Noguchi, E., Russell, P. R., & Masai, H. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m510575200 · Cited by 61 · see citing works

G1 arrest cell-cycle-dependent clastogenesis in UV-irradiated human fibroblasts

Kaufmann, W. K., & Wilson, S. J. (1994) · Mutation Research/DNA Repair · doi:10.1016/0921-8777(94)90062-0 · Cited by 56 · see citing works

Checkpoint Regulation of Replication Dynamics in UV-Irradiated Human Cells

Chastain, P. D., Heffernan, T. P., Nevis, K. R., Li, L., Kaufmann, W. K., Kaufman, D. G., & Cordeiro‐Stone, M. (2006) · Cell Cycle · doi:10.4161/cc.5.18.3236 · Cited by 52 · see citing works

Excision repair of UV- or benzo[a]pyrene diol epoxide-induced lesions in xeroderma pigmentosum variant cells is ‘error free’

Watanabe, M., Maher, V. M., & McCormick, J. J. (1985) · Mutation Research/DNA Repair Reports · doi:10.1016/0167-8817(85)90070-7 · Cited by 48 · see citing works

Spatio‐temporal organization of DNA replication in murine embryonic stem, primary, and immortalized cells

Panning, M. M., & Gilbert, D. M. (2005) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20395 · Cited by 48 · see citing works

Structure of the replication fork in ultraviolet light-irradiated human cells

Cordeiro‐Stone, M., Schumacher, R. I., & Meneghini, R. (1979) · Biophysical Journal · doi:10.1016/s0006-3495(79)85218-2 · Cited by 48 · see citing works

The Cell Cycle and Chemical Carcinogenesis

Grisham, J. W., Kaufmann, W. K., & Kaufman, D. G. (1983) · Pathology and Immunopathology Research · doi:10.1159/000154949 · Cited by 46 · see citing works

Timeless in lung morphogenesis

Xiao, J., Li, C., Zhu, N., Borok, Z., & Minoo, P. (2003) · Developmental Dynamics · doi:10.1002/dvdy.10346 · Cited by 31 · see citing works

Overexpression and Purification of Human XPA Using a Baculovirus Expression System

Hermanson, I. L., & Turchi, J. J. (2000) · Protein Expression and Purification · doi:10.1006/prep.2000.1224 · Cited by 25 · see citing works

Enhanced expression of X-ray- and UV-induced chromosome aberrations by cytosine arabinoside in ataxia telangiectasia cells

Ejima, Y., & Sasaki, M. S. (1986) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(86)90120-x · Cited by 24 · see citing works

ATR: an essential regulator of genome integrity

Cimprich, K. A., & Cortez, D. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2450 · Cited by 1,798 · see citing works

Eukaryotic Chromosome DNA Replication: Where, When, and How?

Masai, H., Matsumoto, S., You, Z., Yoshizawa-Sugata, N., & Oda, M. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.052308.103205 · Cited by 494 · see citing works

RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response

Maréchal, A., & Zou, L. (2015) · Cell Research · doi:10.1038/cr.2014.147 · Cited by 465 · see citing works

Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling

Hardeland, R., Madrid, J. A., Tan, D. X., & Reiter, R. J. (2011) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2011.00934.x · Cited by 449 · see citing works

Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: the molecular choreography

Thompson, L. H. (2012) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2012.06.002 · Cited by 357 · see citing works

Disrupting Circadian Homeostasis of Sympathetic Signaling Promotes Tumor Development in Mice

Lee, S., Donehower, L. A., Herron, A. J., Moore, D. D., & Fu, L. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010995 · Cited by 286 · see citing works

DNA Damage Response: Three Levels of DNA Repair Regulation

Sirbu, B. M., & Cortez, D. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a012724 · Cited by 272 · see citing works

Activation of the ATR kinase by the RPA-binding protein ETAA1

Haahr, P., Hoffmann, S., Tollenaere, M. A. X., Ho, T., Toledo, L. I., Mann, M., Bekker‐Jensen, S., Räschle, M., & Mailand, N. (2016) · Nature Cell Biology · doi:10.1038/ncb3422 · Cited by 255 · see citing works

The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forksPreprint

Bansbach, C. E., Betous, R., Lovejoy, C. A., Glick, G. G., & Cortez, D. (2009) · Genes & Development · doi:10.1101/gad.1839909 · Cited by 252 · see citing works

Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress

Yan, S., Sorrell, M., & Berman, Z. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1666-4 · Cited by 247 · see citing works

The Implications of Multiple Circadian Clock Origins

Rosbash, M. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000062 · Cited by 239 · see citing works

The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restartPreprint

Ciccia, A., Bredemeyer, A. L., Sowa, M. E., Terret, M., Jallepalli, P. V., Harper, J. W., & Elledge, S. J. (2009) · Genes & Development · doi:10.1101/gad.1832309 · Cited by 217 · see citing works

DNA damage tolerance: a double-edged sword guarding the genome.

Ghosal, G., & Chen, J. (2013) · PubMed · doi:10.3978/j.issn.2218-676x.2013.04.01 · Cited by 204 · see citing works

CRY2 and FBXL3 Cooperatively Degrade c-MYC

Huber, A., Papp, S. J., Chan, A. B., Henriksson, E., Jordan, S. D., Kriebs, A., Nguyen, M., Wallace, M., Li, Z., Metallo, C. M., et al. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.10.012 · Cited by 197 · see citing works

Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress

Vassin, V. M., Anantha, R. W., Sokolova, E., Kanner, S., & Borowiec, J. A. (2009) · Journal of Cell Science · doi:10.1242/jcs.053702 · Cited by 188 · see citing works

Replication protein A: directing traffic at the intersection of replication and repair

Oakley, G. G. (2010) · Frontiers in bioscience · doi:10.2741/3652 · Cited by 180 · see citing works

Circadian Clock, Cancer, and Chemotherapy

Sancar, A., Lindsey-Boltz, L. A., Gaddameedhi, S., Selby, C. P., Ye, R., Chiou, Y.-Y., Kemp, M. G., Hu, J., Lee, J. H., & Ozturk, N. (2015) · Biochemistry · doi:10.1021/bi5007354 · Cited by 170 · see citing works

RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination

Inano, S., Sato, K., Katsuki, Y., Kobayashi, W., Tanaka, H., Nakajima, K., Nakada, S., Miyoshi, H., Knies, K., Takaori‐Kondo, A., et al. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.04.022 · Cited by 171 · see citing works

Mechanisms of replication fork protection: a safeguard for genome stability

Errico, A., & Costanzo, V. (2012) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2012.655374 · Cited by 159 · see citing works

An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication

Moiseeva, T. N., Yin, Y., Calderon, M. J., Qian, C., Schamus-Haynes, S., Sugitani, N., Osmanbeyoglu, H. U., Rothenberg, E., Watkins, S. C., & Bakkenist, C. J. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1903418116 · Cited by 149 · see citing works

The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination

O'Donnell, L., Panier, S., Wildenhain, J., Tkach, J. M., Al-Hakim, A., Landry, M.-C., Escribano-Diaz, C., Szilard, R. K., Young, J. T. F., Munro, M., et al. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.10.024 · Cited by 149 · see citing works

Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner

Bianco, J. N., Bergoglio, V., Lin, Y., Pillaire, M., Schmitz, A.-L., Gilhodes, J., Lusque, A., Mazières, J., Lacroix‐Triki, M., Roumeliotis, T. I., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-08886-8 · Cited by 146 · see citing works

Mrc1 and Tof1 Regulate DNA Replication Forks in Different Ways during Normal S Phase

Hodgson, B., Calzada, A., & Labib, K. P. M. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-05-0500 · Cited by 146 · see citing works

The annealing helicase HARP protects stalled replication forksPreprint

Yuan, J., Ghosal, G., & Chen, J. (2009) · Genes & Development · doi:10.1101/gad.1836409 · Cited by 141 · see citing works

Replication protein A: a multifunctional protein with roles in DNA replication, repair and beyond

Dueva, R., & Iliakis, G. E. (2020) · NAR Cancer · doi:10.1093/narcan/zcaa022 · Cited by 130 · see citing works

Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion

Leman, A. R., Noguchi, C., Lee, C. Y., & Noguchi, E. (2010) · Journal of Cell Science · doi:10.1242/jcs.057984 · Cited by 130 · see citing works

Clock Gene Expression Levels and Relationship With Clinical and Pathological Features in Colorectal Cancer Patients

Mazzoccoli, G., Panza, A., Valvano, M. R., Palumbo, O., Carella, M., Pazienza, V., Biscaglia, G., Tavano, F., Sebastiano, P. D., Andriulli, A., et al. (2011) · Chronobiology International · doi:10.3109/07420528.2011.615182 · Cited by 132 · see citing works

Phase Resetting of the Mammalian Circadian Clock by DNA Damage

Oklejewicz, M., Destici, E., Tamanini, F., Hut, R. A., Janssens, R. C., & van der Horst, G. T. J. (2008) · Current Biology · doi:10.1016/j.cub.2008.01.047 · Cited by 132 · see citing works

The FANCM/FAAP24 Complex Is Required for the DNA Interstrand Crosslink-Induced Checkpoint Response

Huang, M., ‍Kim, J. M., Shiotani, B., Yang, K., Zou, L., & D’Andrea, A. D. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.07.005 · Cited by 134 · see citing works

Replication fork dynamics and the DNA damage response

Jones, R. M., & Petermann, E. (2012) · Biochemical Journal · doi:10.1042/bj20112100 · Cited by 127 · see citing works

Single- and double-stranded DNA: building a trigger of ATR-mediated DNA damage response: Figure 1.Preprint

Zou, L. (2007) · Genes & Development · doi:10.1101/gad.1550307 · Cited by 128 · see citing works

Eukaryotic DNA damage checkpoint activation in response to double-strand breaks

Finn, K., Lowndes, N. F., & Grenon, M. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0875-3 · Cited by 127 · see citing works

Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair

Xie, S., Mortusewicz, O., Ma, H. T., Herr, P., Poon, R. Y. C., Helleday, T., & Qian, C. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.07.031 · Cited by 127 · see citing works

Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor

Wang, Z., McGlynn, K. A., Meyts, E. R., Bishop, D. T., Chung, C. C., Dalgaard, M., Greene, M. H., Gupta, R., Grotmol, T., Haugen, T. B., et al. (2017) · Nature Genetics · doi:10.1038/ng.3879 · Cited by 124 · see citing works

Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress

Kemp, M. G., Akan, Z., Yilmaz, S., Grillo, M., Smith‐Roe, S. L., Kang, T., Cordeiro‐Stone, M., Kaufmann, W. K., Abraham, R. T., Sancar, A., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.110304 · Cited by 120 · see citing works

Mechanisms of Dealing with DNA Damage-Induced Replication Problems

Budzowska, M., & Kanaar, R. (2008) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-008-9039-y · Cited by 118 · see citing works

The Intra-S Checkpoint Responses to DNA Damage

Iyer, D., & Rhind, N. (2017) · Genes · doi:10.3390/genes8020074 · Cited by 113 · see citing works

Identification of SMARCAL1 as a Component of the DNA Damage Response

Postow, L., Woo, E. M., Chait, B. T., & Funabiki, H. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.048330 · Cited by 112 · see citing works

Human single-stranded DNA binding proteins are essential for maintaining genomic stability

Ashton, N. W., Bolderson, E., Cubeddu, L., O'Byrne, K. J., & Richard, D. J. (2013) · BMC Molecular Biology · doi:10.1186/1471-2199-14-9 · Cited by 113 · see citing works

Chk1 and Claspin potentiate PCNA ubiquitination

Yang, X. H., Shiotani, B., Classon, M., & Zou, L. (2008) · Genes &amp; Development · doi:10.1101/gad.1632808 · Cited by 111 · see citing works

Dynamic elements of replication protein A at the crossroads of DNA replication, recombination, and repair

Caldwell, C. C., & Spies, M. (2020) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409238.2020.1813070 · Cited by 100 · see citing works

Circadian proteins in the regulation of cell cycle and genotoxic stress responses

Kondratov, R. V., & Antoch, M. P. (2007) · Trends in Cell Biology · doi:10.1016/j.tcb.2007.07.001 · Cited by 103 · see citing works

The Replication Fork: Understanding the Eukaryotic Replication Machinery and the Challenges to Genome Duplication

Leman, A. R., & Noguchi, E. (2013) · Genes · doi:10.3390/genes4010001 · Cited by 102 · see citing works

Hypomorphic PCNA mutation underlies a human DNA repair disorder

Baple, E. L., Chambers, H., Cross, H. E., Fawcett, H., Nakazawa, Y., Chioza, B. A., Harlalka, G. V., Mansour, S., Sreekantan-Nair, A., Patton, M. A., et al. (2014) · Journal of Clinical Investigation · doi:10.1172/jci74593 · Cited by 94 · see citing works

DNA polymerase ε and its roles in genome stability

Henninger, E. E., & Pursell, Z. F. (2014) · IUBMB Life · doi:10.1002/iub.1276 · Cited by 97 · see citing works

Mammalian TIMELESS Is Required for ATM-dependent CHK2 Activation and G2/M Checkpoint Control

Yang, X., Wood, P. A., & Hrushesky, W. J. M. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.050237 · Cited by 94 · see citing works

Tim–Tipin dysfunction creates an indispensible reliance on the ATR–Chk1 pathway for continued DNA synthesis

Smith, K. D., Fu, M. A., & Brown, E. J. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200905006 · Cited by 92 · see citing works

Regulation of DNA replication by the S-phase DNA damage checkpoint

Willis, N. A., & Rhind, N. (2009) · Cell Division · doi:10.1186/1747-1028-4-13 · Cited by 93 · see citing works

Local and global functions of Timeless and Tipin in replication fork protection

Leman, A. R., & Noguchi, E. (2012) · Cell Cycle · doi:10.4161/cc.21989 · Cited by 92 · see citing works

Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in <i>Xenopus</i> egg extracts

Errico, A., Costanzo, V., & Hunt, T. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706347104 · Cited by 92 · see citing works

The Human RNA Polymerase I Transcription Terminator Complex Acts as a Replication Fork Barrier That Coordinates the Progress of Replication with rRNA Transcription Activity

Akamatsu, Y., & Kobayashi, T. (2015) · Molecular and Cellular Biology · doi:10.1128/mcb.01521-14 · Cited by 89 · see citing works

Human CST facilitates genome-wide RAD51 recruitment to GC-rich repetitive sequences in response to replication stress

Chastain, M., Zhou, Q., Shiva, O., Fadri-Moskwik, M., Whitmore, L. S., Jia, P., Dai, X., Huang, C.-H., Ye, P., & Chai, W.-H. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.06.077 · Cited by 79 · see citing works

Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiaePreprint

Szyjka, S. J., Aparicio, J. G., Viggiani, C. J., Knott, S., Xu, W., Tavaré, S., & Aparicio, O. M. (2008) · Genes & Development · doi:10.1101/gad.1660408 · Cited by 89 · see citing works

Replication protein A, the laxative that keeps DNA regular: The importance of RPA phosphorylation in maintaining genome stability

Byrne, B. M., & Oakley, G. G. (2018) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2018.04.005 · Cited by 86 · see citing works

Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1

Kang, T., & Leem, S.-H. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku094 · Cited by 86 · see citing works

Human Immunodeficiency Virus Type 1 Vpr-Binding Protein VprBP, a WD40 Protein Associated with the DDB1-CUL4 E3 Ubiquitin Ligase, Is Essential for DNA Replication and Embryonic Development

McCall, C. M., Miliani de Marval, P. L., Chastain, P. D., Jackson, S. C., He, Y. J., Kotake, Y., Cook, J. G., & Xiong, Y. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00232-08 · Cited by 83 · see citing works

ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells

Despras, E., Daboussi, F., Hyrien, O., Marheineke, K., & Kannouche, P. L. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq046 · Cited by 80 · see citing works

Timeless preserves telomere length by promoting efficient DNA replication through human telomeres

Leman, A. R., Dheekollu, J., Deng, Z., Lee, S. W., Das, M. M., Lieberman, P. M., & Noguchi, E. (2012) · Cell Cycle · doi:10.4161/cc.20810 · Cited by 76 · see citing works

Tipin/Tim1/And1 protein complex promotes Polα chromatin binding and sister chromatid cohesion

Errico, A., Cosentino, C., Rivera, T., Losada, A., Schwob, É., Hunt, T., & Costanzo, V. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.304 · Cited by 78 · see citing works

ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization

Qin, T., Mullan, B. P., Ravindran, R., Messinger, D., Siada, R. G., Cummings, J. R., Harris, M. K., Muruganand, A., Pyaram, K., Miklja, Z., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2021.110216 · Cited by 77 · see citing works

The Role of Circadian Regulation in CancerPreprint

Gery, S., & Koeffler, H. P. (2007) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2007.72.004 · Cited by 76 · see citing works

The role of circadian clock genes in tumors

Li, H.-X. (2019) · OncoTargets and Therapy · doi:10.2147/ott.s203144 · Cited by 77 · see citing works

Timeless couples G‐quadruplex detection with processing by DDX11 helicase during DNA replication

Lerner, L. K., Holzer, S., Kilkenny, M. L., Šviković, S., Murat, P., Schiavone, D., Eldridge, C. B., Bittleston, A., Maman, J. D., Branzei, D., et al. (2020) · The EMBO Journal · doi:10.15252/embj.2019104185 · Cited by 71 · see citing works

Mammalian TIMELESS Is Involved in Period Determination and DNA Damage-Dependent Phase Advancing of the Circadian Clock

Engelen, E., Janssens, R. C., Yagita, K., Smits, V. A. J., van der Horst, G. T. J., & Tamanini, F. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056623 · Cited by 71 · see citing works

SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathwayPreprint

Wu, C.-S. P., Ouyang, J., Mori, E., Nguyen, H. D., Maréchal, A., Hallet, A., Chen, D. J., & Zou, L. (2014) · Genes & Development · doi:10.1101/gad.238535.114 · Cited by 73 · see citing works

A Conserved DNA Damage Response Pathway Responsible for Coupling the Cell Division Cycle to the Circadian and Metabolic Cycles

Chen, Z., & McKnight, S. L. (2007) · Cell Cycle · doi:10.4161/cc.6.23.5041 · Cited by 71 · see citing works

Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases

Cho, W., Kang, Y., An, Y.-Y., Tappin, I., Hurwitz, J., & Lee, J.-K. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222494110 · Cited by 70 · see citing works

Sister acts: coordinating DNA replication and cohesion establishmentPreprint

Sherwood, R., Takahashi, T. S., & Jallepalli, P. V. (2010) · Genes & Development · doi:10.1101/gad.1976710 · Cited by 66 · see citing works

Tim/Timeless, a member of the replication fork protection complex, operates with the Warsaw breakage syndrome DNA helicase DDX11 in the same fork recovery pathway

Calì, F., Bharti, S. K., Perna, R. D., Brosh, R. M., & Pisani, F. M. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv1112 · Cited by 65 · see citing works

RFCCtf18and the Swi1-Swi3 Complex Function in Separate and Redundant Pathways Required for the Stabilization of Replication Forks to Facilitate Sister Chromatid Cohesion inSchizosaccharomyces pombe

Ansbach, A. B., Noguchi, C., Klansek, I. W., Heidlebaugh, M., Nakamura, T., & Noguchi, E. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-06-0618 · Cited by 63 · see citing works

Impact of Age and Insulin-Like Growth Factor-1 on DNA Damage Responses in UV-Irradiated Human Skin

Kemp, M. G., Spandau, D. F., & Travers, J. B. (2017) · Molecules · doi:10.3390/molecules22030356 · Cited by 62 · see citing works

Systematic analysis of circadian genes using genome-wide cDNA microarrays in the inflammatory bowel disease transcriptome

Palmieri, O., Mazzoccoli, G., Bossa, F., Maglietta, R., Palumbo, O., Ancona, N., Corritore, G., Latiano, T., Martino, G., Rubino, R., et al. (2015) · Chronobiology International · doi:10.3109/07420528.2015.1050726 · Cited by 60 · see citing works

Emerging links between the biological clock and the DNA damage response

Collis, S. J., & Boulton, S. J. (2007) · Chromosoma · doi:10.1007/s00412-007-0108-6 · Cited by 58 · see citing works

Interactions between Swi1‐Swi3, Mrc1 and S phase kinase, Hsk1 may regulate cellular responses to stalled replication forks in fission yeast

Shimmoto, M., Matsumoto, S., Odagiri, Y., Noguchi, E., Russell, P. R., & Masai, H. (2009) · Genes to Cells · doi:10.1111/j.1365-2443.2009.01300.x · Cited by 57 · see citing works

Prospects for the Use of ATR Inhibitors to Treat Cancer

Wagner, J. M., & Kaufmann, S. H. (2010) · Pharmaceuticals · doi:10.3390/ph3051311 · Cited by 57 · see citing works

Effect of circadian clock mutations on DNA damage response in mammalian cells

Gaddameedhi, S., Reardon, J. T., Ye, R., Öztürk, N., & Sancar, A. (2012) · Cell Cycle · doi:10.4161/cc.21771 · Cited by 54 · see citing works

BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression

Cohen, S. M., Chastain, P. D., Rosson, G. B., Groh, B. S., Weissman, B. E., Kaufman, D. G., & Bultman, S. J. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq559 · Cited by 55 · see citing works

Global analysis of the eukaryotic pathways and networks regulated by Salmonella typhimurium in mouse intestinal infection in vivo

Liu, X., Lu, R., Xia, Y., & Sun, J. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-722 · Cited by 54 · see citing works

The multiple facets of the intra-S checkpoint

Grallert, B., & Boye, E. (2008) · Cell Cycle · doi:10.4161/cc.6389 · Cited by 54 · see citing works

A Timeless Link Between Circadian Patterns and Disease

Mazzoccoli, G., Laukkanen, M. O., Vinciguerra, M., Colangelo, T., & Colantuoni, V. (2015) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2015.11.007 · Cited by 54 · see citing works

The human intra-S checkpoint response to UVC-induced DNA damage

Kaufmann, W. K. (2009) · Carcinogenesis · doi:10.1093/carcin/bgp230 · Cited by 52 · see citing works

SIRT1 Deacetylates TopBP1 and Modulates Intra-S-Phase Checkpoint and DNA Replication Origin Firing

Wang, R., Lahusen, T. J., Chen, Q., Xu, X., Jenkins, L. M. M., Leo, E., Fu, H., Aladjem, M. I., Pommier, Y. G., Appella, E., et al. (2014) · International Journal of Biological Sciences · doi:10.7150/ijbs.11066 · Cited by 50 · see citing works

AND-1 fork protection function prevents fork resection and is essential for proliferation

Abe, T., Kawasumi, R., Giannattasio, M., Dusi, S., Yoshimoto, Y., Miyata, K., Umemura, K., Hirota, K., & Branzei, D. (2018) · Nature Communications · doi:10.1038/s41467-018-05586-7 · Cited by 50 · see citing works

SDE2 integrates into the TIMELESS-TIPIN complex to protect stalled replication forks

Rageul, J., Park, J. J., Zeng, P. P., Lee, E., Yang, J., Hwang, S., Lo, N., Weinheimer, A. S., Schärer, O. D., Yeo, J.-E., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-19162-5 · Cited by 47 · see citing works

Roles of Human AND-1 in Chromosome Transactions in S Phase

Yoshizawa-Sugata, N., & Masai, H. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m806711200 · Cited by 49 · see citing works

Fanconi anemia proteins and endogenous stresses

Pang, Q., & Andreassen, P. R. (2009) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2009.03.013 · Cited by 49 · see citing works

SWI/SNF complexes are required for full activation of the DNA-damage response

Smith‐Roe, S. L., Nakamura, J., Holley, D., Chastain, P. D., Rosson, G. B., Simpson, D. A., Ridpath, J. R., Kaufman, D. G., Kaufmann, W. K., & Bultman, S. J. (2015) · Oncotarget · doi:10.18632/oncotarget.2715 · Cited by 48 · see citing works

Checkpoint responses to unusual structures formed by DNA repeats

Voineagu, I., Freudenreich, C. H., & Mirkin, S. M. (2009) · Molecular Carcinogenesis · doi:10.1002/mc.20512 · Cited by 48 · see citing works

The histone deacetylase inhibitor LBH589 inhibits expression of mitotic genes causing G2/M arrest and cell death in head and neck squamous cell carcinoma cell lines

Prystowsky, M. B., Adomako, A., Smith, R. V., Kawachi, N., McKimpson, W. M., Atadja, P. W., Chen, Q., Schlecht, N. F., Parish, J. L., Childs, G. J., et al. (2009) · The Journal of Pathology · doi:10.1002/path.2554 · Cited by 48 · see citing works

FEN1 Functions in Long Patch Base Excision Repair Under Conditions of Oxidative Stress in Vertebrate Cells

Asagoshi, K., Tano, K., Chastain, P. D., Adachi, N., Sonoda, E., Kikuchi, K., Koyama, H., Nagata, K., Kaufman, D. G., Takeda, S., et al. (2010) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-09-0253 · Cited by 48 · see citing works

Stalled replication forks: Making ends meet for recognition and stabilization

Masai, H., Tanaka, T., & Kohda, D. (2010) · BioEssays · doi:10.1002/bies.200900196 · Cited by 47 · see citing works

Signaling to the p53 Tumor Suppressor through Pathways Activated by Genotoxic and Non-Genotoxic Stresses

Anderson, C. W., & Appella, E. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-374145-5.00264-3 · Cited by 48 · see citing works

The many facets of the Tim-Tipin protein families’ roles in chromosome biology

McFarlane, R. J., Mian, S., & Dalgaard, J. Z. (2010) · Cell Cycle · doi:10.4161/cc.9.4.10676 · Cited by 46 · see citing works

Mechanisms of ATR-mediated checkpoint signalling

Smits, V. A. J. (2010) · Frontiers in bioscience · doi:10.2741/3649 · Cited by 45 · see citing works

Analysis of re-replication from deregulated origin licensing by DNA fiber spreading

Dorn, E. S., Chastain, P. D., Hall, J. R., & Cook, J. G. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn912 · Cited by 45 · see citing works

Efficient expression and purification of human replication fork-stabilizing factor, Claspin, from mammalian cells: DNA-binding activity and novel protein interactions

Uno, S., & Masai, H. (2011) · Genes to Cells · doi:10.1111/j.1365-2443.2011.01535.x · Cited by 44 · see citing works

Protumorigenic role of Timeless in hepatocellular carcinoma

Elgohary, N., Pellegrino, R., NEUMAN, O., El‐Zawahry, H. M., Saber, M. M., Zeeneldin, A. A., GEFERS, R., EHEMAN, V., Schemmer, P., Schirmacher, P., et al. (2014) · International Journal of Oncology · doi:10.3892/ijo.2014.2751 · Cited by 44 · see citing works

Efficient Herpes Simplex Virus 1 Replication Requires Cellular ATR Pathway Proteins

Mohni, K. N., Dee, A. R., Smith, S., Schumacher, A. J., & Weller, S. K. (2012) · Journal of Virology · doi:10.1128/jvi.02504-12 · Cited by 43 · see citing works

Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns

Errico, A., & Costanzo, V. (2010) · EMBO Reports · doi:10.1038/embor.2010.27 · Cited by 43 · see citing works

89 3 The Tim/Tipin Complex Participates in the DNA Replication Checkpoint and is a Target of Multiple

Kinases, C. (2014)

Checkpoint Regulation of Replication Dynamics in UV-Irradiated Human Cells

Chastain, P. D., Heffernan, T. P., Nevis, K. R., Li, L., Kaufmann, W. K., Kaufman, D. G., & Cordeiro‐Stone, M. (2006) · Cell Cycle · doi:10.4161/cc.5.18.3236 · Cited by 52 · see citing works

Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in <i>Xenopus</i> egg extracts

Errico, A., Costanzo, V., & Hunt, T. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706347104 · Cited by 92 · see citing works

Tim–Tipin dysfunction creates an indispensible reliance on the ATR–Chk1 pathway for continued DNA synthesis

Smith, K. D., Fu, M. A., & Brown, E. J. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200905006 · Cited by 92 · see citing works

Photochemistry and Photobiology, 2015, 91: 109–116 DNA Damage Checkpoint Responses in the S Phase of Synchronized

Fibroblasts, D. H., Chastain, P. D., II, Brylawski, B. P., Zhou, Y. C., Rao, S., Chu, H., Ibrahim, J. G., Kaufmann, W. K., & Cordeiro‐Stone, M. (2014)