Spanos, Christos

DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network

Carraro, M., Hendriks, I. A., Hammond, C. M., Solis, V., Völker-Albert, M., Elsborg, J. D., Weisser, M. B., Spanos, C., Montoya, G., Rappsilber, J., et al. (2022) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 62

PLK1-mediated phosphorylation cascade activates Mis18 complex to ensure centromere inheritance

Parashara, P., Medina-Pritchard, B., Abad, M. A., Sotelo-Parrilla, P., Thamkachy, R., Grundei, D., Zou, J., Spanos, C., Kumar, C. N., Basquin, C., et al. (2024) · Science

Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics

Cited by 36

Substrate specificity of the TRAMP nuclear surveillance complexes

Delan-Forino, C., Spanos, C., Rappsilber, J., & Tollervey, D. (2020) · Nature Communications

RNA Research and SplicingNuclear Structure and Function

Cited by 36

RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit

Milligan, L., Sayou, C., Tuck, A., Auchynnikava, T., Reid, J. E., Alexander, R., Alves, F. D. L., Allshire, R., Spanos, C., Rappsilber, J., et al. (2017) · eLife

RNA Research and SplicingGenomics and Chromatin Dynamics

Cited by 23

Mapping the invisible chromatin transactions of prophase chromosome remodeling

Samejima, I., Spanos, C., Samejima, K., Rappsilber, J., Kustatscher, G., & Earnshaw, W. C. (2022) · Molecular Cell

Genomics and Chromatin DynamicsMicrotubule and mitosis dynamics

Cited by 21

Mapping the invisible chromatin transactions of prophase chromosome remodelling

Samejima, I., Spanos, C., Samejima, K., Rappsilber, J., Kustatscher, G., & Earnshaw, W. C. (2021) · Molecular Cell

Genomics and Chromatin DynamicsMicrotubule and mitosis dynamics

Cited by 21

Proteasome-dependent truncation of the negative heterochromatin regulator Epe1 mediates antifungal resistance

Yaseen, I., White, S. A., Torres-Garcia, S., Spanos, C., Lafos, M., Gaberdiel, E., Yeboah, R., El Karoui, M., Rappsilber, J., Pidoux, A. L., et al. (2022) · Nature Structural & Molecular Biology

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 20

Nucleosomal asymmetry shapes histone mark binding and promotes poising at bivalent domains

Bryan, E., Valsakumar, D., Idigo, N. J., Warburton, M., Webb, K. M., McLaughlin, K. A., Spanos, C., Lenci, S., Major, V., Ambrosi, C., et al. (2025) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 16

The SPARC complex defines RNAPII promoters in Trypanosoma brucei

Staneva, D. P., Bresson, S., Auchynnikava, T., Spanos, C., Rappsilber, J., Jeyaprakash, A. A., Tollervey, D., Matthews, K. R., & Allshire, R. C. (2022) · eLife

Genomics and Chromatin DynamicsTrypanosoma species research and implications

Cited by 13

The SPARC complex defines RNAPII promoters in Trypanosoma brucei

Staneva, D. P., Bresson, S., Auchynnikava, T., Spanos, C., Rappsilber, J., Jeyaprakash, A. A., Tollervey, D., Matthews, K. R., & Allshire, R. C. (2022) · eLife

Genomics and Chromatin DynamicsTrypanosoma species research and implications

Cited by 13

Molecular basis for condensin enrichment at pericentromeres

Wang, M., Zou, J., Spanos, C., Rappsilber, J., & Marston, A. L. (2024) · The EMBO Journal

Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics

Cited by 10

The kinetoplastid kinetochore protein KKT23 acetyltransferase is a structural homolog of GCN5 that acetylates the histone H2A C-terminal tail

Ludzia, P., Ishii, M., Deák, G., Spanos, C., Wilson, M. D., Redfield, C., & Akiyoshi, B. (2025) · Structure

Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics

Cited by 6

Differentiation granules, a dynamic regulator of T. brucei development

Cayla, M., Spanos, C., McWilliam, K., Waskett, E., Rappsilber, J., & Matthews, K. R. (2024) · Nature Communications

Trypanosoma species research and implicationsRNA Research and Splicing

Cited by 5

Differentiation granules, a dynamic regulator of T. brucei development.

Cayla, M., Spanos, C., Waskett, E., Rappsilber, J., & Matthews, K. (2023) · Nature Communications

Trypanosoma species research and implicationsRNA Research and Splicing

Cited by 5

Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins

Carloni, R., Devlin, T., Tong, P., Spanos, C., Auchynnikava, T., Rappsilber, J., Matthews, K. R., & Allshire, R. C. (2026) · eLife

Trypanosoma species research and implicationsGenomics and Chromatin Dynamics

Cited by 1

Fission yeast Caprin protein is required for efficient heterochromatin establishment

Zhang, H., Kapitonova, E., Orrego, A., Spanos, C., Strachan, J., & Bayne, E. H. (2025) · PLOS Genetics

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 1

Dysfunction of a SET3-like complex underlies a family of related neurological disorders

Paton, K. M., Alexander-Howden, B., Hare, J. I., Guy, J., Chhatbar, K., Yudina, M., Morris, S. T., Walls, R., Mathieson, T., Spanos, C., et al. (2026) · Nature Communications

Genetics and Neurodevelopmental DisordersGenomics and Rare Diseases

Cited by 0

Hap2-Ino80 facilitated transcription promotes de novo establishment of CENP-A chromatin

Singh, P. P., Shukla, M., White, S. A., Tong, P., Auchynnikava, T., Spanos, C., Rappsilber, J., Pidoux, A. L., & Allshire, R. C. (2019) · bioRxiv (Cold Spring Harbor Laboratory)

Genomics and Chromatin DynamicsMicrotubule and mitosis dynamics

Cited by 0

Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins

Carloni, R., Devlin, T., Tong, P., Spanos, C., Auchynnikava, T., Rappsilber, J., Matthews, K. R., & Allshire, R. C. (2026) · eLife

Trypanosoma species research and implicationsChromosomal and Genetic Variations

Cited by 0

Tetramerisation governs SALL transcription factor function in development and disease

Giuliani, S., Chhatbar, K., Wear, M., Guy, J., Mathieson, T., Burdett, H., George, L., Alston, G., Spanos, C., McHugh, T., et al. (2025) · bioRxiv

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 0