Walker, Lary C.

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

Jucker, M., & Walker, L. C. (2013) · Nature

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 1,663

Exogenous Induction of Cerebral ß-Amyloidogenesis Is Governed by Agent and Host

Meyer-Luehmann, M., Coomaraswamy, J., Bolmont, T., Kaeser, S., Schaefer, C., Kilger, E., Neuenschwander, A., Abramowski, D., Frey, P., Jaton, A. L., et al. (2006) · Science

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 971

Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders

Jucker, M., & Walker, L. C. (2011) · Annals of Neurology

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 622

Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis

Eisele, Y. S., Obermüller, U., Heilbronner, G., Baumann, F., Kaeser, S. A., Wolburg, H., Walker, L. C., Staufenbiel, M., Heikenwalder, M., & Jucker, M. (2010) · Science

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 568

Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases

Jucker, M., & Walker, L. C. (2018) · Nature Neuroscience

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 450

Evidence for Seeding of β-Amyloid by Intracerebral Infusion of Alzheimer Brain Extracts in β-Amyloid Precursor Protein-Transgenic Mice

Kane, M. D., Lipinski, W. J., Callahan, M. J., Bian, F., Durham, R. A., Schwarz, R. D., Roher, A. E., & Walker, L. C. (2000) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 394

Neurodegenerative Diseases: Expanding the Prion Concept

Walker, L. C., & Jucker, M. (2015) · Annual Review of Neuroscience

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 361

Alzheimer's disease: From immunotherapy to immunoprevention

Jucker, M., & Walker, L. C. (2023) · Cell

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 353

Induction of cerebral β-amyloidosis: Intracerebral versus systemic Aβ inoculation

Eisele, Y. S., Bolmont, T., Heikenwalder, M., Langer, F., Jacobson, L. H., Yan, Z.-X., Roth, K., Aguzzi, A., Staufenbiel, M., Walker, L. C., et al. (2009) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 279

Augmented Senile Plaque Load in Aged Female β-Amyloid Precursor Protein-Transgenic Mice

Callahan, M. J., Lipinski, W. J., Bian, F., Durham, R. A., Pack, A., & Walker, L. C. (2001) · The American Journal of Pathology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 274

Soluble Aβ Seeds Are Potent Inducers of Cerebral β-Amyloid Deposition

Langer, F., Eisele, Y. S., Fritschi, S. K., Staufenbiel, M., Walker, L. C., & Jucker, M. (2011) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 237

Mechanisms of Protein Seeding in Neurodegenerative Diseases

Walker, L. C., Diamond, M. I., Duff, K. E., & Hyman, B. T. (2013) · JAMA Neurology

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 226

Amyloid-Associated Neuron Loss and Gliogenesis in the Neocortex of Amyloid Precursor Protein Transgenic Mice

Bondolfi, L., Calhoun, M., Ermini, F., Kuhn, H. G., Wiederhold, K.-H., Walker, L., Staufenbiel, M., & Jucker, M. (2002) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeurogenesis and neuroplasticity mechanisms

Cited by 213

Tauopathy with paired helical filaments in an aged chimpanzee

Rosen, R. F., Farberg, A. S., Gearing, M., Dooyema, J., M. Long, P., Anderson, D. C., Davis‐Turak, J., Coppola, G., Geschwind, D. H., Paré, J., et al. (2008) · Journal of Comparative Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 153

Amyloid in the brains of aged squirrel monkeys

Walker, L. C., Masters, C., Beyreuther, K., & Price, D. L. (1990) · Acta Neuropathologica

Intracerebral and Subarachnoid Hemorrhage ResearchAlzheimer's disease research and treatments

Cited by 119

Aged Non‐Human Primates: An Animal Model of Age‐Associated Neurodegenerative Disease

Price, D. L., Martin, L. J., Sisodia, S. S., Wagster, M. V., Koo, E. H., Walker, L. C., Koliatsos, V. E., & Cork, L. C. (1991) · Brain Pathology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 100

Exogenous induction of cerebral β-amyloidosis in βAPP-transgenic mice

Walker, L. C., Callahan, M. J., Bian, F., Durham, R. A., Roher, A. E., & Lipinski, W. J. (2002) · Peptides

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 96

Senile plaques in aged squirrel monkeys

Walker, L. C., Kitt, C. A., Schwam, E., Buckwald, B., Garcia, F., Sepinwall, J., & Price, D. L. (1987) · Neurobiology of Aging

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 94

Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life

Uhlmann, R. E., Rother, C., Rasmussen, J., Schelle, J., Bergmann, C., Ullrich Gavilanes, E. M., Fritschi, S. K., Buehler, A., Baumann, F., Skodras, A., et al. (2020) · Nature Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 87

The Age of Biosenescence and the Incidence of Cerebral β‐Amyloidosis in Aged Captive Rhesus Monkeys a

UNO, H., & WALKER, L. C. (1993) · Annals of the New York Academy of Sciences

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 57

Comparative pathobiology of β-amyloid and the unique susceptibility of humans to Alzheimer's disease

Rosen, R. F., Tomidokoro, Y., Farberg, A. S., Dooyema, J., Ciliax, B., Preuss, T. M., Neubert, T. A., Ghiso, J. A., LeVine, H., & Walker, L. C. (2016) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 46

Vasopressin and oxytocin gene expression in the human hypothalamus

Sukhov, R. R., Walker, L. C., Rance, N. E., Price, D. L., & Young, W. S. (1993) · Journal of Comparative Neurology

Neuroendocrine regulation and behaviorNeuropeptides and Animal Physiology

Cited by 39

Experimental evidence for temporal uncoupling of brain Aβ deposition and neurodegenerative sequelae

Rother, C., Uhlmann, R. E., Müller, S. A., Schelle, J., Skodras, A., Obermüller, U., Häsler, L. M., Lambert, M., Baumann, F., Xu, Y., et al. (2022) · Nature Communications

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 28