Streit, Wolfgang J.

Microglia states and nomenclature: A field at its crossroads

Paolicelli, R. C., Sierra, A., Stevens, B., Tremblay, M.-E., Aguzzi, A., Ajami, B., Amit, I., Audinat, E., Bechmann, I., Bennett, M., et al. (2022) · Neuron

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 1,973

Reactive microgliosis

Streit, W. J., Walter, S. A., & Pennell, N. A. (1999) · Progress in Neurobiology

Neuroinflammation and Neurodegeneration MechanismsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 1,096

Down-Regulation of the Macrophage Lineage Through Interaction with OX2 (CD200)

Hoek, R. M., Ruuls, S. R., Murphy, C. A., Wright, G. J., Goddard, R., Zurawski, S. M., Blom, B., Homola, M. E., Streit, W. J., Brown, M. H., et al. (2000) · Science

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 1,022

Microglia as neuroprotective, immunocompetent cells of the CNS

Streit, W. J. (2002) · Glia

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 919

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease

Streit, W. J., Braak, H., Xue, Q.-S., & Bechmann, I. (2009) · Acta Neuropathologica

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 727

Dystrophic microglia in the aging human brain

Streit, W. J., Sammons, N. W., Kuhns, A. J., & Sparks, D. L. (2004) · Glia

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 705

Microglial senescence: does the brain's immune system have an expiration date?

Streit, W. J. (2006) · Trends in Neurosciences

Neuroinflammation and Neurodegeneration MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 397

Microglia in the Aging Brain

Conde, J. R., & Streit, W. J. (2006) · Journal of Neuropathology and Experimental Neurology

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 344

Microglia and Alzheimer's disease pathogenesis

Streit, W. J. (2004) · Journal of Neuroscience Research

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 335

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function

Njie, E. G., Boelen, E., Stassen, F. R., Steinbusch, H. W. M., Borchelt, D. R., & Streit, W. J. (2012) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 335

Microglial pathology

Streit, W. J., Xue, Q.-S., Tischer, J., & Bechmann, I. (2014) · Acta Neuropathologica Communications

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 317

Comprehensive characterization and failure modes of tungsten microwire arrays in chronic neural implants

Prasad, A., Xue, Q.-S., Sankar, V., Nishida, T., Shaw, G., Streit, W. J., & Sanchez, J. C. (2012) · Journal of Neural Engineering

Neuroscience and Neural EngineeringAnalog and Mixed-Signal Circuit Design

Cited by 298

Beyond Activation: Characterizing Microglial Functional Phenotypes

Lier, J., Streit, W. J., & Bechmann, I. (2021) · Cells

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 274

Evidence That Aging And Amyloid Promote Microglial Cell Senescence

Flanary, B. E., Sammons, N. W., Nguyen, C., Walker, D., & Streit, W. J. (2007) · Rejuvenation Research

Neuroinflammation and Neurodegeneration MechanismsTelomeres, Telomerase, and Senescence

Cited by 272

Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity

Lopes, K. O., Sparks, D. L., & Streit, W. J. (2008) · Glia

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 262

TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice

Frank, S., Burbach, G. J., Bonin, M., Walter, M., Streit, W., Bechmann, I., & Deller, T. (2008) · Glia

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 247

Life and Death of Microglia

Streit, W. J., & Xue, Q.-S. (2009) · Journal of Neuroimmune Pharmacology

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 205

Abiotic-biotic characterization of Pt/Ir microelectrode arrays in chronic implants

Prasad, A., Xue, Q.-S., Dieme, R., Sankar, V., Mayrand, R. C., Nishida, T., Streit, W. J., & Sanchez, J. C. (2014) · Frontiers in Neuroengineering

Neuroscience and Neural EngineeringAnalog and Mixed-Signal Circuit Design

Cited by 178

Progressive telomere shortening occurs in cultured rat microglia, but not astrocytes

Flanary, B. E., & Streit, W. J. (2004) · Glia

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 167

Dystrophic microglia in late‐onset Alzheimer's disease

Streit, W. J., Khoshbouei, H., & Bechmann, I. (2020) · Glia

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 152

The effects of aging, injury and disease on microglial function: a case for cellular senescence

Miller, K. R., & Streit, W. J. (2007) · Neuron Glia Biology

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 134

Microglial activation occurs late during preclinical Alzheimer's disease

Streit, W. J., Braak, H., Del Tredici, K., Leyh, J., Lier, J., Khoshbouei, H., Eisenlöffel, C., Müller, W., & Bechmann, I. (2018) · Glia

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 98

Effect of aging on the microglial response to peripheral nerve injury

Conde, J. R., & Streit, W. J. (2006) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 86

Human CNS immune senescence and neurodegeneration

Streit, W. J., & Xue, Q.-S. (2014) · Current Opinion in Immunology

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 86