Moon, Randall T.

WNT and β-catenin signalling: diseases and therapies

Moon, R. T., Kohn, A. D., Ferrari, G. V. D., & Kaykas, A. (2004) · Nature Reviews Genetics

Wnt/β-catenin signaling in development and cancerHedgehog Signaling Pathway Studies

Cited by 1,763

A Second Canon

Veeman, M. T., Axelrod, J. D., & Moon, R. T. (2003) · Developmental Cell

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 1,359

Zebrafish Prickle, a Modulator of Noncanonical Wnt/Fz Signaling, Regulates Gastrulation Movements

Veeman, M. T., Slusarski, D. C., Kaykas, A., Louie, S. H., & Moon, R. T. (2003) · Current Biology

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 945

Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development

Bernier, R., Golzio, C., Xiong, B., Stessman, H. A., Coe, B. P., Penn, O., Witherspoon, K., Gerdts, J., Baker, C., Vulto-van Silfhout, A. T., et al. (2014) · Cell

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 798

Wnt and calcium signaling: β-Catenin-independent pathways

Kohn, A. D., & Moon, R. T. (2005) · Cell Calcium

Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease

Cited by 730

Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling

Slusarski, D. C., Corces, V. G., & Moon, R. T. (1997) · Nature

Wnt/β-catenin signaling in development and cancerReceptor Mechanisms and Signaling

Cited by 680

Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery

Angers, S., Li, T., Yi, X., MacCoss, M. J., Moon, R. T., & Zheng, N. (2006) · Nature

Ubiquitin and proteasome pathwaysEnzyme Structure and Function

Cited by 674

Signal transduction through beta-catenin and specification of cell fate during embryogenesis.

Miller, J. R., & Moon, R. T. (1996) · Genes & Development

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 656

Ca2+/Calmodulin-dependent Protein Kinase II Is Stimulated by Wnt and Frizzled Homologs and Promotes Ventral Cell Fates in Xenopus

Kühl, M., Sheldahl, L. C., Malbon, C. C., & Moon, R. T. (2000) · Journal of Biological Chemistry

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 517

High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping

Czerniecki, S. M., Cruz, N. M., Harder, J. L., Menon, R., Annis, J., Otto, E. A., Gulieva, R. E., Islas, L. V., Kim, Y. K., Tran, L. M., et al. (2018) · Cell Stem Cell

Pluripotent Stem Cells ResearchRenal and related cancers

Cited by 465

Porous Implants Modulate Healing and Induce Shifts in Local Macrophage Polarization in the Foreign Body Reaction

Sussman, E. M., Halpin, M. C., Muster, J., Moon, R. T., & Ratner, B. D. (2014) · Annals of Biomedical Engineering

Tissue Engineering and Regenerative MedicineBone Tissue Engineering Materials

Cited by 416

Modulation of Embryonic Intracellular Ca2+Signaling byWnt-5A

Slusarski, D. C., Yang-Snyder, J., Busa, W. B., & Moon, R. T. (1997) · Developmental Biology

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 404

The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos

Park, M., & Moon, R. T. (2002) · Nature Cell Biology

Developmental Biology and Gene RegulationWnt/β-catenin signaling in development and cancer

Cited by 381

Macrophages modulate adult zebrafish tail fin regeneration

Petrie, T. A., Strand, N. S., Tsung-Yang, C., Rabinowitz, J. S., & Moon, R. T. (2014) · Development

Zebrafish Biomedical Research ApplicationsWound Healing and Treatments

Cited by 365

The KLHL12–Cullin-3 ubiquitin ligase negatively regulates the Wnt–β-catenin pathway by targeting Dishevelled for degradation

Angers, S., Thorpe, C. J., Biechele, T. L., Goldenberg, S. J., Zheng, N., MacCoss, M. J., & Moon, R. T. (2006) · Nature Cell Biology

Wnt/β-catenin signaling in development and cancerUbiquitin and proteasome pathways

Cited by 364

Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos

Sheldahl, L. C., Slusarski, D. C., Pandur, P., Miller, J. R., Kühl, M., & Moon, R. T. (2003) · The Journal of Cell Biology

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 350

A Transgenic Lef1/β-Catenin-Dependent Reporter Is Expressed in Spatially Restricted Domains throughout Zebrafish Development

Dorsky, R. I., Sheldahl, L. C., & Moon, R. T. (2002) · Developmental Biology

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 287

Direct regulation of nacre , a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway

Dorsky, R. I., Raible, D. W., & Moon, R. T. (2000) · Genes & Development

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 279

Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS)

Korvatska, O., Strand, N. S., Berndt, J. D., Strovas, T., Chen, D.-H., Leverenz, J. B., Kiianitsa, K., Mata, I. F., Karakoc, E., Greenup, J. L., et al. (2013) · Human Molecular Genetics

Parkinson's Disease Mechanisms and TreatmentsRNA Research and Splicing

Cited by 140

nemo-like kinase is an essential co-activator of Wnt signaling during early zebrafish development

Thorpe, C. J., & Moon, R. T. (2004) · Development

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 84