Lukiw, Walter J.

Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression

Marcheselli, V. L., Hong, S., Lukiw, W. J., Tian, X. H., Gronert, K., Musto, A., Hardy, M., Gimenez, J. M., Chiang, N., Serhan, C. N., et al. (2003) · Journal of Biological Chemistry

Fatty Acid Research and HealthNeuroprotection in Cerebral Ischemia

Cited by 802

Circular RNA (circRNA) in Alzheimer’s disease (AD)

Lukiw, W. J. (2013) · Frontiers in Genetics

Circular RNAs in diseasesAlzheimer's disease research and treatments

Cited by 636

Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling

Colangelo, V., Schurr, J., Ball, M. J., Pelaez, R. P., Bazan, N. G., & Lukiw, W. J. (2002) · Journal of Neuroscience Research

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 517

An NF-κB-sensitive Micro RNA-146a-mediated Inflammatory Circuit in Alzheimer Disease and in Stressed Human Brain Cells

Lukiw, W. J., Zhao, Y., & Cui, J. G. (2008) · Journal of Biological Chemistry

Neuroinflammation and Neurodegeneration MechanismsMicroRNA in disease regulation

Cited by 441

Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer's disease temporal lobe neocortex

Sethi, P., & Lukiw, W. J. (2009) · Neuroscience Letters

MicroRNA in disease regulationNeuroinflammation and Neurodegeneration Mechanisms

Cited by 409

Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus

Zhao, Y., Jaber, V., & Lukiw, W. J. (2017) · Frontiers in Cellular and Infection Microbiology

Alzheimer's disease research and treatmentsGut microbiota and health

Cited by 379

Differential Regulation of Interleukin-1 Receptor-associated Kinase-1 (IRAK-1) and IRAK-2 by MicroRNA-146a and NF-κB in Stressed Human Astroglial Cells and in Alzheimer Disease

Cui, J. G., Li, Y. Y., Zhao, Y., Bhattacharjee, S., & Lukiw, W. J. (2010) · Journal of Biological Chemistry

Neuroinflammation and Neurodegeneration MechanismsMicroRNA in disease regulation

Cited by 274

Docosahexaenoic Acid-Derived Neuroprotectin D1 Induces Neuronal Survival via Secretase- and PPARγ-Mediated Mechanisms in Alzheimer's Disease Models

Zhao, Y., Calon, F., Julien, C., Winkler, J. W., Petasis, N. A., Lukiw, W. J., & Bazan, N. G. (2011) · PLoS ONE

Alzheimer's disease research and treatmentsFatty Acid Research and Health

Cited by 243

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration

Bhattacharjee, S., Zhao, Y., Dua, P., Rogaev, E. I., & Lukiw, W. J. (2016) · PLOS ONE

Retinal Diseases and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 147

Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture

Lukiw, W. J., Percy, M. E., & Kruck, T. P. (2005) · Journal of Inorganic Biochemistry

Aluminum toxicity and tolerance in plants and animalsHeavy Metal Exposure and Toxicity

Cited by 140

Increased expression of miRNA-146a in Alzheimer's disease transgenic mouse models

Li, Y. Y., Cui, J. G., Hill, J. M., Bhattacharjee, S., Zhao, Y., & Lukiw, W. J. (2011) · Neuroscience Letters

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 135

Characterization of an NF-κB-regulated, miRNA-146a-mediated down-regulation of complement factor H (CFH) in metal-sulfate-stressed human brain cells

Pogue, A. I., Li, Y. Y., Cui, J.-G., Zhao, Y., Kruck, T. P. A., Percy, M. E., Tarr, M. A., & Lukiw, W. J. (2009) · Journal of Inorganic Biochemistry

Aluminum toxicity and tolerance in plants and animalsMicroRNA in disease regulation

Cited by 133

HSV-1 infection of human brain cells induces miRNA-146a and alzheimer-type inflammatory signaling.

Hill, J. M., Zhao, Y., Clement, C., Neumann, D. M., & Lukiw, W. J. (2009) · NeuroReport

Neuroinflammation and Neurodegeneration MechanismsHerpesvirus Infections and Treatments

Cited by 130

Retinal amyloid peptides and complement factor H in transgenic models of Alzheimer's disease

Alexandrov, P. N., Pogue, A., Bhattacharjee, S., & Lukiw, W. J. (2011) · Neuroreport

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 128

Up-regulated Pro-inflammatory MicroRNAs (miRNAs) in Alzheimer’s disease (AD) and Age-Related Macular Degeneration (AMD)

Pogue, A. I., & Lukiw, W. J. (2018) · Cellular and Molecular Neurobiology

MicroRNA in disease regulationNeuroinflammation and Neurodegeneration Mechanisms

Cited by 105

The Gastrointestinal Tract Microbiome and Potential Link to Alzheimer’s Disease

Hill, J. M., Bhattacharjee, S., Pogue, A. I., & Lukiw, W. J. (2014) · Frontiers in Neurology

Gut microbiota and healthAlzheimer's disease research and treatments

Cited by 98

Spreading of Alzheimer’s disease inflammatory signaling through soluble micro-RNA

Lukiw, W. J., Alexandrov, P. N., Zhao, Y., Hill, J. M., & Bhattacharjee, S. (2012) · NeuroReport

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 90

Intracerebral propagation of Alzheimer’s disease: strengthening evidence of a herpes simplex virus etiology

Ball, M. J., Lukiw, W. J., Kammerman, E. M., & Hill, J. M. (2013) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsHerpesvirus Infections and Treatments

Cited by 89

Changes in Chromatin Structure Associated with Alzheimer’s Disease

Lewis, P. N., Lukiw, W. J., De Boni, U., & Crapper McLachlan, D. R. (1981) · Journal of Neurochemistry

Genomics and Chromatin DynamicsAlzheimer's disease research and treatments

Cited by 78

Alzheimer's disease--a dysfunction in cholesterol and lipid metabolism

Lukiw, W. J., Pappolla, M., Pelaez, R. P., & Bazan, N. G. (2005) · Cellular and Molecular Neurobiology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 59

Chromosome 21-Encoded microRNAs (mRNAs): Impact on Down’s Syndrome and Trisomy-21 Linked Disease

Alexandrov, P. N., Percy, M. E., & Lukiw, W. J. (2018) · Cellular and Molecular Neurobiology

Down syndrome and intellectual disability researchMicroRNA in disease regulation

Cited by 44

Deficits in the miRNA-34a-regulated endogenous TREM2 phagocytosis sensor-receptor in Alzheimer’s disease (AD); an update

Bhattacharjee, S., Zhao, Y., & Lukiw, W. J. (2014) · Frontiers in Aging Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 34