Zhao, Chao

Myelin Impairs CNS Remyelination by Inhibiting Oligodendrocyte Precursor Cell Differentiation

Kotter, M. R., Li, W.-W., Zhao, C., & Franklin, R. J. M. (2006) · The Journal of Neuroscience

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 768

CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination

Zawadzka, M., Rivers, L. E., Fancy, S. P. J., Zhao, C., Tripathi, R., Jamen, F., Young, K., Goncharevich, A., Pohl, H., Rizzi, M., et al. (2010) · Cell stem cell

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 650

The Age-Related Decrease in CNS Remyelination Efficiency Is Attributable to an Impairment of Both Oligodendrocyte Progenitor Recruitment and Differentiation

Sim, F. J., Zhao, C., Penderis, J., & Franklin, R. J. M. (2002) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 625

Retinoid X receptor gamma signaling accelerates CNS remyelination

Huang, J. K., Jarjour, A. A., Nait Oumesmar, B., Kerninon, C., Williams, A., Krezel, W., Kagechika, H., Bauer, J., Zhao, C., Evercooren, A. B.-V., et al. (2011) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 547

Regulatory T cells promote myelin regeneration in the central nervous system

Dombrowski, Y., O'Hagan, T., Dittmer, M., Penalva, R., Mayoral, S. R., Bankhead, P., Fleville, S., Eleftheriadis, G., Zhao, C., Naughton, M., et al. (2017) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 533

Niche stiffness underlies the ageing of central nervous system progenitor cells

Segel, M., Neumann, B., Hill, M. F. E., Weber, I. P., Viscomi, C., Zhao, C., Young, A., Agley, C. C., Thompson, A. J., Gonzalez, G. A., et al. (2019) · Nature

Neurogenesis and neuroplasticity mechanismsCellular Mechanics and Interactions

Cited by 532

Metformin restores CNS remyelination capacity by rejuvenating aged stem cells

Neumann, B., Baror, R., Zhao, C., Segel, M., Dietmann, S., Rawji, K. S., Foerster, S., McClain, C. R., Chalut, K., van Wijngaarden, P., et al. (2019) · Cell Stem Cell

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 449

bHLH Transcription Factor Olig1 Is Required to Repair Demyelinated Lesions in the CNS

Arnett, H. A., Fancy, S. P. J., Alberta, J. A., Zhao, C., Plant, S. R., Kaing, S., Raine, C. S., Rowitch, D. H., Franklin, R. J. M., & Stiles, C. D. (2004) · Science

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 416

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

Fancy, S. P. J., Harrington, E. P., Yuen, T. J., Silbereis, J. C., Zhao, C., Baranzini, S. E., Bruce, C. C., Otero, J. J., Huang, E. J., Nusse, R., et al. (2011) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsNeonatal and fetal brain pathology

Cited by 349

Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression

Kotter, M. R., Zhao, C., van Rooijen, N., & Franklin, R. J. M. (2005) · Neurobiology of Disease

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 331

Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination

Chong, S. Y. C., Rosenberg, S. S., Fancy, S. P. J., Zhao, C., Shen, Y.-A. A., Hahn, A. T., McGee, A. W., Xu, X., Zheng, B., Zhang, L. I., et al. (2012) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 232

Differences in the early inflammatory responses to toxin-induced demyelination are associated with the age-related decline in CNS remyelination

Zhao, C., Li, W.-W., & Franklin, R. J. M. (2006) · Neurobiology of Aging

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 142

Inhibition of CNS Remyelination by the Presence of Semaphorin 3A

Syed, Y. A., Hand, E., Möbius, W., Zhao, C., Hofer, M., Nave, K. A., & Kotter, M. R. (2011) · The Journal of Neuroscience

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 134

Tamoxifen accelerates the repair of demyelinated lesions in the central nervous system

Gonzalez, G. A., Hofer, M. P., Syed, Y. A., Amaral, A. I., Rundle, J., Rahman, S., Zhao, C., & Kotter, M. R. N. (2016) · Scientific Reports

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 86

Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination

Yuen, T. J., Johnson, K. R., Miron, V. E., Zhao, C., Quandt, J., Harrisingh, M. C., Swire, M., Williams, A., McFarland, H. F., Franklin, R. J. M., et al. (2013) · Brain

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 80

Stem cells, progenitors and myelin repair

Zhao, C., Fancy, S. P. J., Magy, L., Urwin, J. E., & Franklin, R. J. M. (2005) · Journal of Anatomy

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 61

Inhibition of phosphodiesterase‐4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination

Syed, Y. A., Baer, A., Hofer, M. P., González, G. A., Rundle, J., Myrta, S., Huang, J. K., Zhao, C., Rossner, M. J., Trotter, M. W. B., et al. (2013) · EMBO Molecular Medicine

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 58

Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination

Syed, Y. A., Zhao, C., Mahad, D., Möbius, W., Altmann, F., Foss, F., Sentürk, A., Acker-Palmer, A., Lubec, G., Lilley, K., et al. (2016) · Acta Neuropathologica

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 50

Osteopontin is extensively expressed by macrophages following CNS demyelination but has a redundant role in remyelination

Zhao, C., Fancy, S. P. J., ffrench-Constant, C., & Franklin, R. J. M. (2008) · Neurobiology of Disease

Multiple Sclerosis Research StudiesBone and Dental Protein Studies

Cited by 47

The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination

McMurran, C. E., Guzman de la Fuente, A., Penalva, R., Ben Menachem-Zidon, O., Dombrowski, Y., Falconer, J., Gonzalez, G. A., Zhao, C., Krause, F. N., Young, A. M. H., et al. (2019) · Proceedings of the National Academy of Sciences

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 39

Myt1L Promotes Differentiation of Oligodendrocyte Precursor Cells and is Necessary for Remyelination After Lysolecithin-Induced Demyelination.

Shi, Y., Shao, Q., Li, Z., Gonzalez, G. A., Lu, F., Wang, D., Pu, Y., Huang, A., Zhao, C., He, C., et al. (2018) · Neuroscience Bulletin

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 34

Remyelination of chronic demyelinated lesions with directly induced neural stem cells

Peruzzotti-Jametti, L., Vicario, N., Volpe, G., Rizzi, S., Kwok, C., Lombardi, I., Bergholt, M. S., Barea-Moya, L., D’Angelo, A., Nicaise, A. M., et al. (2025) · Brain

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 8