Ferrucci, Luigi

Plasma BDNF concentration, Val66Met genetic variant and depression- related personality traits

Terracciano, A., Martin, B., Ansari, D., Tanaka, T., Ferrucci, L., Maudsley, S., Mattson, M. P., & Costa, P. T. (2010) · Genes, Brain and Behavior

Neurotransmitter Receptor Influence on BehaviorNerve injury and regeneration

Cited by 63

The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis

Xu, Y., Derakhshan, A., Hysaj, O., Wildisen, L., Ittermann, T., Pingitore, A., Abolhassani, N., Medici, M., Kiemeney, L. A. L. M., Riksen, N. P., et al. (2023) · The Lancet Diabetes & Endocrinology

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 61

Upregulated ex vivo expression of stress-responsive inflammatory pathway genes by LPS-challenged CD14(+) monocytes in frail older adults

Qu, T., Walston, J. D., Yang, H., Fedarko, N. S., Xue, Q.-L., Beamer, B. A., Ferrucci, L., Rose, N. R., & Leng, S. X. (2009) · Mechanisms of Ageing and Development

Frailty in Older AdultsGenetics, Aging, and Longevity in Model Organisms

Cited by 61

Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity

Lee-Chang, C., Bodogai, M., Moritoh, K., Olkhanud, P. B., Chan, A. C., Croft, M., Mattison, J. A., Holst, P. J., Gress, R. E., Ferrucci, L., et al. (2014) · Blood

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 58

Plaque composition in the proximal superficial femoral artery and peripheral artery disease events

McDermott, M. M., Kramer, C. M., Tian, L., Carr, J., Guralnik, J. M., Polonsky, T., Carroll, T., Kibbe, M., Criqui, M. H., Ferrucci, L., et al. (2017) · JACC: Cardiovascular Imaging

Peripheral Artery Disease ManagementAtherosclerosis and Cardiovascular Diseases

Cited by 55

A Research Agenda: The Changing Relationship Between Body Weight and Health in Aging

Alley, D. E., Ferrucci, L., Barbagallo, M., Studenski, S. A., & Harris, T. B. (2008) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Nutrition and Health in AgingBody Composition Measurement Techniques

Cited by 55

Impaired glucose tolerance in midlife and longitudinal changes in brain function during aging

Thambisetty, M., Beason-Held, L. L., An, Y., Kraut, M., Metter, J., Egan, J., Ferrucci, L., O'Brien, R., & Resnick, S. M. (2013) · Neurobiology of Aging

Dementia and Cognitive Impairment ResearchAdvanced MRI Techniques and Applications

Cited by 54

A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin

Levine, M., McDevitt, R. A., Meer, M., Perdue, K., Di Francesco, A., Meade, T., Farrell, C., Thrush, K., Wang, M., Dunn, C., et al. (2020) · eLife

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 52

DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice

Herman, A. B., Tsitsipatis, D., Anerillas, C., Mazan-Mamczarz, K., Carr, A. E., Gregg, J. M., Wang, M., Zhang, J., Michel, M., Henry-Smith, C. A., et al. (2023) · Journal of Clinical Investigation

Telomeres, Telomerase, and SenescenceAtherosclerosis and Cardiovascular Diseases

Cited by 50

A brain proteomic signature of incipient Alzheimer’s disease in young APOE ε4 carriers identifies novel drug targets

Roberts, J. A., Varma, V. R., An, Y., Varma, S., Candia, J., Fantoni, G., Tiwari, V., Anerillas, C., Williamson, A., Saito, A., et al. (2021) · Science Advances

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 49

DHEAS levels and mortality in disabled older women: the Women's Health and Aging Study I

Cappola, A. R., Xue, Q.-L., Walston, J. D., Leng, S. X., Ferrucci, L., Guralnik, J., & Fried, L. P. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Hormonal and reproductive studiesMenopause: Health Impacts and Treatments

Cited by 49

Inflammation and Trajectory of Renal Function in Community‐Dwelling Older Adults

Salimi, S., Shardell, M. D., Seliger, S. L., Bandinelli, S., Guralnik, J. M., & Ferrucci, L. (2018) · Journal of the American Geriatrics Society

Chronic Kidney Disease and DiabetesDialysis and Renal Disease Management

Cited by 48

Assessment of NAD(+)metabolism in human cell cultures, erythrocytes, cerebrospinal fluid and primate skeletal muscle

Demarest, T. G., Truong, G. T. D., Lovett, J., Mohanty, J. G., Mattison, J. A., Mattson, M. P., Ferrucci, L., Bohr, V. A., & Moaddel, R. (2019) · Analytical Biochemistry

Sirtuins and Resveratrol in MedicineMetabolomics and Mass Spectrometry Studies

Cited by 48

Searching for a mitochondrial root to the decline in muscle function with ageing

Gonzalez‐Freire, M., Adelnia, F., Moaddel, R., & Ferrucci, L. (2018) · Journal of Cachexia, Sarcopenia and Muscle

Nutrition and Health in AgingMitochondrial Function and Pathology

Cited by 48

Omega-3 blood levels and stroke risk: a pooled and harmonized analysis of 183 291 participants from 29 prospective studies

O’Keefe, J. H., Tintle, N. L., Harris, W. S., O’Keefe, E. L., Sala-Vila, A., Attia, J., Garg, G. M., Hure, A., Bork, C. S., Schmidt, E. B., et al. (2024) · Stroke

Fatty Acid Research and HealthNutritional Studies and Diet

Cited by 46

Distinct senotypes in p16- and p21-positive cells across human and mouse aging tissues

Saul, D., Jurk, D., Doolittle, M. L., Kosinsky, R. L., Han, Y., Zhang, X., Franco, A. C., Kim, S. Y., Wyles, S. P., Prakash, Y. S., et al. (2025) · The EMBO Journal

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 45

Nonsteroidal Anti‐Inflammatory Drugs, Aspirin, and Cognitive Function in the Baltimore Longitudinal Study of Aging

Waldstein, S. R., Wendell, C. R., Seliger, S. L., Ferrucci, L., Metter, E. J., & Zonderman, A. B. (2010) · Journal of the American Geriatrics Society

Dementia and Cognitive Impairment ResearchPharmaceutical Practices and Patient Outcomes

Cited by 44

Poor mitochondrial health and systemic inflammation? Test of a classic hypothesis in the Baltimore Longitudinal Study of Aging

Zampino, M., Brennan, N. A., Kuo, P.-L., Spencer, R. G., Fishbein, K. W., Simonsick, E. M., & Ferrucci, L. (2020) · GeroScience

Mitochondrial Function and PathologyExercise and Physiological Responses

Cited by 43

Mild thyroid hormone excess is associated with a decreased physical function in elderly men

Ceresini, G., Ceda, G. P., Lauretani, F., Maggio, M., Bandinelli, S., Guralnik, J. M., Cappola, A. R., Usberti, E., Morganti, S., Valenti, G., et al. (2011) · The Aging Male

Thyroid Disorders and TreatmentsHormonal and reproductive studies

Cited by 41

Free Thyroxine and Functional Mobility, Fitness, and Fatigue in Euthyroid Older Men and Women in the Baltimore Longitudinal Study of Aging

Simonsick, E. M., Chia, C. W., Mammen, J. S., Egan, J. M., & Ferrucci, L. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Thyroid Disorders and TreatmentsHormonal and reproductive studies

Cited by 38

Gonadal status and physical performance in older men

Maggio, M., Ceda, G. P., Lauretani, F., Bandinelli, S., Metter, E. J., Guralnik, J. M., Basaria, S., Cattabiani, C., Luci, M., Dall'Aglio, E., et al. (2011) · The Aging Male

Hormonal and reproductive studiesNutrition and Health in Aging

Cited by 38

Changes in anthropometric measures in men and women across the life-span: findings from the InCHIANTI study.

Bartali, B., Benvenuti, E., Corsi, A. M., Bandinelli, S., Russo, C. R., Di Iorio, A., Lauretani, F., & Ferrucci, L. (2002) · Sozial- und Präventivmedizin¶Social and Preventive Medicine¶Médecine social et préventive

Body Composition Measurement TechniquesNutrition and Health in Aging

Cited by 37

Is taurine an aging biomarker?

Fernandez, M. E., Bernier, M., Price, N. L., Camandola, S., Aon, M. A., Vaughan, K., Mattison, J. A., Preston, J. D., Jones, D. P., Tanaka, T., et al. (2025) · Science

Aldose Reductase and TaurineGenetics, Aging, and Longevity in Model Organisms

Cited by 33

Age-associated alterations in inducible gene transcription in human CD4+ T lymphocytes

Bektas, A., Zhang, Y., Wood, W. H., Becker, K. G., Madara, K., Ferrucci, L., & Sen, R. (2013) · Aging

T-cell and B-cell ImmunologyNF-κB Signaling Pathways

Cited by 31