Slominski, Andrzej T.

20 S-Hydroxyvitamin D3, Noncalcemic Product of CYP11A1 Action on Vitamin D3, Exhibits Potent Antifibrogenic Activity in Vivo

Slominski, A., Janjetovic, Z., Tuckey, R. C., Nguyen, M. N., Bhattacharya, K. G., Wang, J., Li, W., Jiao, Y., Gu, W., Brown, M., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism

Systemic Sclerosis and Related DiseasesVitamin D Research Studies

Cited by 89

Production of 22-hydroxy metabolites of vitamin D3 by cytochrome p450scc (CYP11A1) and analysis of their biological activities on skin cells

Tuckey, R. C., Li, W., Shehabi, H. Z., Janjetovic, Z., Nguyen, M. N., Kim, T.-K., Chen, J., Howell, D. E., Benson, H. A. E., Sweatman, T., et al. (2011) · Drug Metabolism and Disposition

Vitamin D Research StudiesSteroid Chemistry and Biochemistry

Cited by 88

Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterols

Slominski, A. T., Kim, T.-K., Hobrath, J. V., Janjetovic, Z., Oak, A. S. W., Postlethwaite, A., Lin, Z., Li, W., Takeda, Y., Jetten, A. M., et al. (2017) · Scientific Reports

Cholesterol and Lipid MetabolismPsoriasis: Treatment and Pathogenesis

Cited by 82

Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes

Slominski, A. T., Kim, T.-K., Chen, J., Nguyen, M. N., Li, W., Yates, C. R., Sweatman, T., Janjetovic, Z., & Tuckey, R. C. (2012) · The International Journal of Biochemistry & Cell Biology

Steroid Chemistry and BiochemistryCholesterol and Lipid Metabolism

Cited by 81

Cutaneous glucocorticosteroidogenesis: securing local homeostasis and the skin integrity

Slominski, A. T., Manna, P. R., & Tuckey, R. C. (2014) · Experimental Dermatology

Dermatology and Skin DiseasesAdrenal Hormones and Disorders

Cited by 79

Nrf2 in keratinocytes modulates UVB-induced DNA damage and apoptosis in melanocytes through MAPK signaling

Jeayeng, S., Wongkajornsilp, A., Slominski, A. T., Jirawatnotai, S., Sampattavanich, S., & Panich, U. (2017) · Free Radical Biology and Medicine

melanin and skin pigmentationSkin Protection and Aging

Cited by 78

Ultraviolet B stimulates production of corticotropin releasing factor (CRF) by human melanocytes

Slominski, A., Baker, J., Ermak, G., Chakraborty, A., & Pawelek, J. (1996) · FEBS Letters

melanin and skin pigmentationNeuropeptides and Animal Physiology

Cited by 78

Novel non-calcemic secosteroids that are produced by human epidermal keratinocytes protect against solar radiation

Slominski, A. T., Janjetovic, Z., Kim, T.-K., Wasilewski, P., Rosas, S., Hanna, S., Sayre, R. M., Dowdy, J. C., Li, W., & Tuckey, R. C. (2015) · The Journal of Steroid Biochemistry and Molecular Biology

Skin Protection and AgingVitamin D Research Studies

Cited by 77

Novel vitamin D photoproducts and their precursors in the skin

Slominski, A., Kim, T.-K., Zmijewski, M. A., Janjetovic, Z., Li, W., Chen, J., Kusniatsova, E. I., Semak, I., Postlethwaite, A., Miller, D. D., et al. (2013) · Dermato-Endocrinology

Vitamin D Research StudiesSteroid Chemistry and Biochemistry

Cited by 76

On the role of the corticotropin-releasing hormone signalling system in the aetiology of inflammatory skin disorders

Slominski, A. (2009) · British Journal of Dermatology

Stress Responses and CortisolDermatology and Skin Diseases

Cited by 74

Expression of the vitamin D–activating enzyme 1α-hydroxylase (CYP27B1) decreases during melanoma progression

Brożyna, A. A., Jóźwicki, W., Janjetovic, Z., & Slominski, A. T. (2013) · Human Pathology

Cutaneous Melanoma Detection and ManagementVitamin D Research Studies

Cited by 70

Enzymatic Metabolism of Ergosterol by Cytochrome P450scc to Biologically Active 17α,24-Dihydroxyergosterol

Slominski, A., Semak, I., Zjawiony, J., Wortsman, J., Gandy, M. N., Li, J., Zbytek, B., Li, W., & Tuckey, R. C. (2005) · Chemistry & Biology

Steroid Chemistry and BiochemistryCholesterol and Lipid Metabolism

Cited by 69

Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activity

Li, W., Chen, J., Janjetovic, Z., Kim, T.-K., Sweatman, T., Lu, Y., Zjawiony, J., Tuckey, R. C., Miller, D., & Slominski, A. (2010) · Steroids

Vitamin D Research StudiesSteroid Chemistry and Biochemistry

Cited by 68

Correlation between secosteroid-induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strength

Kim, T.-K., Wang, J., Janjetovic, Z., Chen, J., Tuckey, R. C., Nguyen, M. N., Tang, E. K. Y., Miller, D., Li, W., & Slominski, A. T. (2012) · Molecular and Cellular Endocrinology

Vitamin D Research StudiesRetinoids in leukemia and cellular processes

Cited by 67

Cultured human dermal fibroblasts do produce cortisol

Slominski, A., Zbytek, B., Szczesniewski, A., & Wortsman, J. (2006) · Journal of Investigative Dermatology

Adrenal Hormones and DisordersHair Growth and Disorders

Cited by 66

Photo-conversion of two epimers (20R and 20S) of pregna-5,7-diene-3β, 17α, 20-triol and their bioactivity in melanoma cells

Zmijewski, M. A., Li, W., Zjawiony, J. K., Sweatman, T. W., Chen, J., Miller, D. D., & Slominski, A. T. (2009) · Steroids

Vitamin D Research StudiesSteroid Chemistry and Biochemistry

Cited by 62

Metabolism of progesterone to DOC, corticosterone and 18OHDOC in cultured human melanoma cells

Slominski, A., Gomez-Sanchez, C. E., Foecking, M. F., & Wortsman, J. (1999) · FEBS Letters

Adrenal Hormones and DisordersSteroid Chemistry and Biochemistry

Cited by 60

Characterization of a ultraviolet B-induced corticotropin-releasing hormone-proopiomelanocortin system in human melanocytes

Zbytek, B., Wortsman, J., & Slominski, A. (2006) · Molecular Endocrinology

Neuropeptides and Animal Physiologymelanin and skin pigmentation

Cited by 60

Metabolism of cholesterol, vitamin D3 and 20-hydroxyvitamin D3 incorporated into phospholipid vesicles by human CYP27A1

Tieu, E. W., Li, W., Chen, J., Baldisseri, D. M., Slominski, A. T., & Tuckey, R. C. (2012) · The Journal of Steroid Biochemistry and Molecular Biology

Vitamin D Research StudiesSteroid Chemistry and Biochemistry

Cited by 56

Melatonin and Its Metabolites Ameliorate UVR-Induced Mitochondrial Oxidative Stress in Human MNT-1 Melanoma Cells

Kleszczyński, K., Bilska, B., Stegemann, A., Flis, D. J., Ziolkowski, W., Pyza, E., Luger, T. A., Reiter, R. J., Böhm, M., & Slominski, A. T. (2018) · International Journal of Molecular Sciences

Circadian rhythm and melatoninmelanin and skin pigmentation

Cited by 54

Vitamin D analogs 17, 20S(OH)2pD and 17,20R(OH)2pD are noncalcemic and exhibit antifibrotic activity

Slominski, A. T., Li, W., Bhattacharya, S. K., Smith, R. A., Johnson, P. L., Chen, J., Nelson, K. E., Tuckey, R. C., Miller, D., Jiao, Y., et al. (2011) · Journal of Investigative Dermatology

Vitamin D Research StudiesParathyroid Disorders and Treatments

Cited by 51

Synthesis and photochemical transformation of 3β,21-dihydroxypregna-5,7-dien-20-one to novel secosteroids that show anti-melanoma activity

Zmijewski, M. A., Li, W., Chen, J., Kim, T.-K., Zjawiony, J. K., Sweatman, T. W., Miller, D. D., & Slominski, A. T. (2011) · Steroids

Vitamin D Research StudiesSteroid Chemistry and Biochemistry

Cited by 51

Vitamin D derivatives enhance cytotoxic effects of H2O2 or cisplatin on human keratinocytes

Piotrowska, A., Wierzbicka, J., Ślebioda, T., Woźniak, M., Tuckey, R. C., Slominski, A. T., & Żmijewski, M. A. (2016) · Steroids

Vitamin D Research StudiesPhotodynamic Therapy Research Studies

Cited by 48

Metabolism of vitamin D2 to 17, 20,24-trihydroxyvitamin D2 by cytochrome p450scc (CYP11A1)

Nguyen, M. N., Slominski, A., Li, W., Ng, Y. R., & Tuckey, R. C. (2009) · Drug Metabolism and Disposition

Vitamin D Research StudiesSteroid Chemistry and Biochemistry

Cited by 48