Milaneschi, Yuri

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

eQTLGen, Wray, N. R., 23andMe, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 3,005

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Program, T. M. V., Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., Ntritsos, G., Dimou, N., Cabrera, C. P., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 1,381

Depression and obesity: evidence of shared biological mechanisms

Milaneschi, Y., Simmons, W. K., van Rossum, E. F. C., & Penninx, B. W. (2019) · Molecular Psychiatry

Regulation of Appetite and ObesityEating Disorders and Behaviors

Cited by 1,073

The genetic architecture of the human cerebral cortex

Grasby, K. L., Jahanshad, N., Painter, J. N., Colodro-Conde, L., Bralten, J., Hibar, D. P., Lind, P. A., Pizzagalli, F., Ching, C. R. K., McMahon, M. A. B., et al. (2020) · Science

Genetic Associations and EpidemiologyCognitive Abilities and Testing

Cited by 876

Common genetic variants influence human subcortical brain structures

Initiative, T. A. D. N., Hibar, D. P., The CHARGE Consortium, EPIGEN, IMAGEN, SYS, Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., et al. (2015) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 858

Understanding the somatic consequences of depression: biological mechanisms and the role of depression symptom profile

Penninx, B. W., Milaneschi, Y., Lamers, F., & Vogelzangs, N. (2013) · BMC Medicine

Stress Responses and CortisolTryptophan and brain disorders

Cited by 839

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

the Alzheimer’s Disease Neuroimaging Initiative, E. C., Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., et al. (2014) · Brain Imaging and Behavior

Genetic Associations and EpidemiologyFunctional Brain Connectivity Studies

Cited by 838

A saturated map of common genetic variants associated with human height

Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., et al. (2022) · Nature

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 825

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23andMe Research Team, Walters, R. K., Polimanti, R., Johnson, E. C., McClintick, J. N., Adams, M. J., Adkins, A. E., Aliev, F., Bacanu, S.-A., Batzler, A., et al. (2018) · Nature Neuroscience

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 632

Meta-analysis of genome-wide association studies for neuroticism, and the polygenic association with major depressive disorder

de Moor, M. H. M., van den Berg, S. M., Verweij, K. J. H., Krueger, R. F., Luciano, M., Arias Vasquez, A., Matteson, L. K., Derringer, J., Esko, T., Amin, N., et al. (2015) · JAMA Psychiatry

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 345

Minimal phenotyping yields genome-wide association signals of low specificity for major depression

MDD Working Group of the Psychiatric Genomics Consortium, Cai, N., Revez, J. A., Adams, M. J., Andlauer, T. F. M., Breen, G., Byrne, E. M., Clarke, T.-K., Forstner, A. J., Grabe, H. J., et al. (2020) · Nature Genetics

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 344

Novel genetic loci associated with hippocampal volume

Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., et al. (2017) · Nature Communications

Genetic Associations and EpidemiologyMemory and Neural Mechanisms

Cited by 299

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., Power, R. A., Ripke, S., Stahl, E. A., Starnawska, A., et al. (2019) · American Journal of Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 270

A Higher Adherence to a Mediterranean-Style Diet Is Inversely Associated with the Development of Frailty in Community-Dwelling Elderly Men and Women,

Talegawkar, S. A., Bandinelli, S., Bandeen-Roche, K., Chen, P., Milaneschi, Y., Tanaka, T., Semba, R. D., Guralnik, J. M., & Ferrucci, L. (2012) · The Journal of Nutrition

Nutritional Studies and DietFrailty in Older Adults

Cited by 265

Epigenetic aging in major depressive disorder

Han, L. K. M., Aghajani, M., Clark, S. L., Chan, R. F., Hattab, M. W., Shabalin, A. A., Zhao, M., Kumar, G., Xie, L. Y., Jansen, R., et al. (2018) · American Journal of Psychiatry

Epigenetics and DNA MethylationTreatment of Major Depression

Cited by 260

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

Schumann, G., Liu, C., O’Reilly, P., Gao, H., Song, P., Xu, B., Ruggeri, B., Amin, N., Jia, T., Preis, S., et al. (2016) · Proceedings of the National Academy of Sciences

Fibroblast Growth Factor ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 241

Genetic association of major depression with atypical features and obesity-related immunometabolic dysregulations

Milaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., Dehghan, A., Forstner, A. J., Grabe, H. J., Homuth, G., Kan, C., et al. (2017) · JAMA Psychiatry

Genetic Associations and EpidemiologyTryptophan and brain disorders

Cited by 233

Gene expression in major depressive disorder

Jansen, R., Penninx, B. W. J. H., Madar, V, Xia, K., Milaneschi, Y., Hottenga, J. J., Hammerschlag, A. R., Beekman, A., van der Wee, N., Smit, J. H., et al. (2016) · Molecular Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 224

Effect of polygenic risk scores on depression in childhood trauma

Peyrot, W. J., Milaneschi, Y., Abdellaoui, A., Sullivan, P. F., Hottenga, J. J., Boomsma, D. I., & Penninx, B. W. J. H. (2014) · British Journal of Psychiatry

Genetic Associations and EpidemiologyChild Abuse and Trauma

Cited by 209

Leptin dysregulation is specifically associated with major depression with atypical features: evidence for a mechanism connecting obesity and depression

Milaneschi, Y., Lamers, F., Bot, M., Drent, M. L., & Penninx, B. W. J. H. (2017) · Biological Psychiatry

Regulation of Appetite and ObesityTreatment of Major Depression

Cited by 209

Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it?

Levinson, D. F., Mostafavi, S., Milaneschi, Y., Rivera, M., Ripke, S., Wray, N. R., & Sullivan, P. F. (2014) · Biological Psychiatry

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 159

Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric disorders: Evidence through univariate and multivariate mega-analysis including 6420 participants from the ENIGMA MDD working group

Opel, N., Thalamuthu, A., Milaneschi, Y., Grotegerd, D., Flint, C., Leenings, R., Goltermann, J., Richter, M., Hahn, T., Woditsch, G., et al. (2021) · Molecular Psychiatry

Neural and Behavioral Psychology StudiesGenetic Associations and Epidemiology

Cited by 148

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., et al. (2019) · Nature Communications

Epigenetics and DNA MethylationBirth, Development, and Health

Cited by 143

An integrative study of five biological clocks in somatic and mental health

Jansen, R., Han, L. K., Verhoeven, J. E., Aberg, K. A., van den Oord, E. C., Milaneschi, Y., & Penninx, B. W. (2021) · eLife

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 127