Roelfsema, Ferdinand

An amplitude-specific divergence in the pulsatile mode of growth hormone (GH) secretion underlies the gender difference in mean GH concentrations in men and premenopausal women.

van den Berg, G., Veldhuis, J. D., Frölich, M., & Roelfsema, F. (1996) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 293

Obesity due to Melanocortin 4 Receptor (MC4R) Deficiency Is Associated with Increased Linear Growth and Final Height, Fasting Hyperinsulinemia, and Incompletely Suppressed Growth Hormone Secretion

Martinelli, C. E., Keogh, J. M., Greenfield, J. R., Henning, E., van der Klaauw, A. A., Blackwood, A., O'Rahilly, S., Roelfsema, F., Camacho-Hübner, C., Pijl, H., et al. (2011) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsRegulation of Appetite and Obesity

Cited by 153

High prevalence of vertebral fractures despite normal bone mineral density in patients with long-term controlled acromegaly

Wassenaar, M. J. E., Biermasz, N. R., Hamdy, N. A. T., Zillikens, M. C., van Meurs, J. B. J., Rivadeneira, F., Hofman, A., Uitterlinden, A. G., Stokkel, M. P. M., Roelfsema, F., et al. (2011) · European Journal of Endocrinology

Pituitary Gland Disorders and TreatmentsBone health and osteoporosis research

Cited by 144

High Circulating Thyrotropin Levels in Obese Women Are Reduced after Body Weight Loss Induced by Caloric Restriction

Kok, P., Roelfsema, F., Langendonk, J. G., Frölich, M., Burggraaf, J., Meinders, A. E., & Pijl, H. (2005) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsRegulation of Appetite and Obesity

Cited by 132

Hypopituitarism following traumatic brain injury: prevalence is affected by the use of different dynamic tests and different normal values

Kokshoorn, N. E., Wassenaar, M. J. E., Biermasz, N. R., Roelfsema, F., Smit, J. W. A., Romijn, J. A., & Pereira, A. M. (2010) · European Journal of Endocrinology

Pituitary Gland Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 129

Thyrotropin secretion patterns in health and disease

Roelfsema, F., & Veldhuis, J. D. (2013) · Endocrine Reviews

Thyroid Disorders and TreatmentsCircadian rhythm and melatonin

Cited by 113

Age-Dependent and Gender-Dependent Regulation of Hypothalamic-Adrenocorticotropic-Adrenal Axis

Veldhuis, J. D., Sharma, A., & Roelfsema, F. (2013) · Endocrinology and Metabolism Clinics of North America

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 110

Growth hormone (GH) secretion in patients with an inactivating defect of the GH-releasing hormone (GHRH) receptor is pulsatile: evidence for a role for non-GHRH inputs into the generation of GH pulses.

Roelfsema, F., Biermasz, N. R., Veldman, R. G., Veldhuis, J. D., Frölich, M., Stokvis-Brantsma, W. H., & Wit, J.-M. (2001) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 106

Impact of age, sex and body mass index on cortisol secretion in 143 healthy adults

Roelfsema, F., van Heemst, D., Iranmanesh, A., Takahashi, P., Yang, R., & Veldhuis, J. D. (2017) · Endocrine Connections

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 100

Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism

Jansen, S. W., Akintola, A. A., Roelfsema, F., van der Spoel, E., Cobbaert, C. M., Ballieux, B. E., Egri, P., Kvarta-Papp, Z., Gereben, B., Fekete, C., et al. (2015) · Scientific Reports

Thyroid Disorders and TreatmentsGenetics, Aging, and Longevity in Model Organisms

Cited by 82

Effects of dehydroepiandrostenedione, superimposed on growth hormone substitution, on quality of life and insulin-like growth factor I in patients with secondary adrenal insufficiency: a randomized, placebo-controlled, cross-over trial.

van Thiel, S. W., Romijn, J. A., Pereira, A. M., Biermasz, N. R., Roelfsema, F., van Hemert, A., Ballieux, B., & Smit, J. W. A. (2005) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersHormonal and reproductive studies

Cited by 66

Low prevalence of hypopituitarism after traumatic brain injury: a multicenter study

Kokshoorn, N. E., Smit, J. W. A., Nieuwlaat, W. A., Tiemensma, J., Bisschop, P. H., Groote Veldman, R., Roelfsema, F., Franken, A. A. M., Wassenaar, M. J. E., Biermasz, N. R., et al. (2011) · European Journal of Endocrinology

Pituitary Gland Disorders and TreatmentsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 65

Proinflammatory Cytokine Infusion Attenuates LH's Feedforward on Testosterone Secretion: Modulation by Age

Veldhuis, J., Yang, R., Roelfsema, F., & Takahashi, P. (2016) · The Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesHormonal and reproductive studies

Cited by 65

Long‐term skeletal effects of recombinant human growth hormone (rhGH) alone and rhGH combined with alendronate in GH‐deficient adults: a seven‐year follow‐up study

Biermasz, N. R., Hamdy, N. A. T., Pereira, A. M., Romijn, J. A., & Roelfsema, F. (2004) · Clinical Endocrinology

Growth Hormone and Insulin-like Growth FactorsBone health and osteoporosis research

Cited by 54

Gender, age, body mass index, and IGF-I individually and jointly determine distinct GH dynamics: analyses in one hundred healthy adults

Veldhuis, J. D., Roelfsema, F., Keenan, D. M., & Pincus, S. (2011) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsPituitary Gland Disorders and Treatments

Cited by 53

Growth hormone dynamics in healthy adults are related to age and sex and strongly dependent on body mass index

Roelfsema, F., & Veldhuis, J. D. (2016) · Neuroendocrinology

Growth Hormone and Insulin-like Growth FactorsPituitary Gland Disorders and Treatments

Cited by 53

Basal, Pulsatile, Entropic (Patterned), and Spiky (Staccato-like) Properties of ACTH Secretion: Impact of Age, Gender, and Body Mass Index

Veldhuis, J. D., Roelfsema, F., Iranmanesh, A., Carroll, B. J., Keenan, D. M., & Pincus, S. M. (2009) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 51

Retention of Estradiol Negative Feedback Relationship to LH Predicts Ovulation in Response to Caloric Restriction and Weight Loss in Obese Patients with Polycystic Ovary Syndrome

van Dam, E. W. C. M., Roelfsema, F., Veldhuis, J. D., Hogendoorn, S., Westenberg, J., Helmerhorst, F. M., Frölich, M., Krans, H. M. J., Meinders, A. E., & Pijl, H. (2004) · American Journal of Physiology-Endocrinology and Metabolism

Ovarian function and disordersHypothalamic control of reproductive hormones

Cited by 51

Contribution from local conversion of thyroxine to 3,5,3'-triiodothyronine to intracellular 3,5,3'-triiodothyronine in several organs in hypothyroid rats at isotope equilibrium

van Doom, J., Roelfsema, F., & van der Heide, D. (1982) · Acta Endocrinologica

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 50

Thyrotropin secretion in mild and severe primary hypothyroidism is distinguished by amplified burst mass and basal secretion with increased spikiness and approximate entropy

Roelfsema, F., Pereira, A. M., Adriaanse, R., Endert, E., Fliers, E., Romijn, J. A., & Veldhuis, J. D. (2010) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 45

Familial longevity is associated with higher tsh secretion and strong TSH-fT3 relationship

Jansen, S. W., Roelfsema, F., van der Spoel, E., Akintola, A. A., Postmus, I., Ballieux, B. E., Slagboom, P. E., Cobbaert, C. M., van der Grond, J., Westendorp, R. G., et al. (2015) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 41

Sex defines the age dependence of endogenous ACTH-cortisol dose responsiveness

Keenan, D. M., Roelfsema, F., Carroll, B. J., Iranmanesh, A., & Veldhuis, J. D. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 41

Mutations in IRS4 are associated with central hypothyroidism

Heinen, C. A., de Vries, E. M., Alders, M., Bikker, H., Zwaveling-Soonawala, N., van den Akker, E. L. T., Bakker, B., Hoorweg-Nijman, G., Roelfsema, F., Hennekam, R. C., et al. (2018) · Journal of Medical Genetics

Thyroid Disorders and TreatmentsHypothalamic control of reproductive hormones

Cited by 38

Irregular and frequent cortisol secretory episodes with preserved diurnal rhythmicity in primary adrenal Cushing's syndrome

van Aken, M. O., Pereira, A. M., van Thiel, S. W., van den Berg, G., Frölich, M., Veldhuis, J. D., Romijn, J. A., & Roelfsema, F. (2005) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersAdrenal and Paraganglionic Tumors

Cited by 31